Blar i Bergen Open Research Archive på forfatter "Bolstad, Anne Isine"
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Angiogenic and Immunomodulatory Properties of Endothelial and Mesenchymal Stem Cells
Bartaula-Brevik, Sushma; Pedersen, Torbjørn O.; Finne-Wistrand, Anna; Bolstad, Anne Isine; Mustafa, Kamal (Journal article, 2016)It has been suggested that the effect of implanted cells on the local environment is important when selecting the appropriate cell type for tissue regeneration. Our aim was to compare the local tissue response to implanted ... -
Angiogenic and Immunomodulatory Properties of Endothelial and Mesenchymal Stem Cells
Bartaula, Sushma; Pedersen, Torbjørn Østvik; Finne-Wistrand, Anna; Bolstad, Anne Isine; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2016-02)It has been suggested that the effect of implanted cells on the local environment is important when selecting the appropriate cell type for tissue regeneration. Our aim was to compare the local tissue response to implanted ... -
Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjogren's syndrome in salivary glands of non-obese diabetic mice
Gatumu, Margaret Karimi; Skarstein, Kathrine; Papandile, Adrian; Browning, Jeffrey L.; Fava, Roy A.; Bolstad, Anne Isine (Peer reviewed; Journal article, 2009-02-18)Introduction The lymphotoxin-beta receptor (LTβR) pathway is important in the development and maintenance of lymphoid structures. Blocking this pathway has proven beneficial in murine models of autoimmune diseases such as ... -
Bone regeneration in rat calvarial defects using dissociated or spheroid mesenchymal stromal cells in scaffold-hydrogel constructs
Shanbhag, Siddharth; Suliman, Salwa; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Kampleitner, Carina; Hassan, Mohamed Nageeb; Heimel, Patrick; Dobsak, Toni; Tangl, Stefan; Bolstad, Anne Isine; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021)Background Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation of bone marrow mesenchymal stromal cells (BMSC). 3D printing offers the possibility to produce customized scaffolds for complex ... -
Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs
Shanbhag, Siddharth; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Yassin, Mohammed Ahmed Alamin Yousif; Dongre, Harsh Nitin; Costea, Daniela Elena; Tangl, Stefan; Stavropoulos, Andreas; Bolstad, Anne Isine; Suliman, Salwa; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021-11-30)Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation and bone regeneration capacity of mesenchymal stromal cells (MSC). Gingiva-derived progenitor cells (GPC) represent a less invasive alternative ... -
Epidemiology of Sjögrens syndrome-from an oral perspective
Bolstad, Anne Isine; Skarstein, Kathrine (Peer reviewed; Journal article, 2016)Oral symptoms are among the most distressing manifestations for patients with Sjögren’s syndrome (SS). The feeling of dry mouth is unpleasant, and hyposalivation may contribute to difficulty in speaking, chewing and ... -
A five-year prospective study of fatigue in primary Sjögren’s syndrome
Haldorsen, Karstein; Bjelland, Ingvar; Bolstad, Anne Isine; Jonsson, Roland; Brun, Johan Gorgas (Peer reviewed; Journal article, 2011-10-13)Introduction: Fatigue is prevalent in primary Sjögren’s syndrome (pSS), and contributes to the considerably reduced health related quality of life in this disease. The symptom is included in proposed disease activity and ... -
Influence of platelet storage time on human platelet lysates and platelet lysate-expanded mesenchymal stromal cells for bone tissue engineering
Shanbhag, Siddharth; Mohamed Ahmed, Samih; Lunde, Turid Helen Felli; Suliman, Salwa; Bolstad, Anne Isine; Hervig, Tor; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2020)Background Human platelet lysate (HPL) is emerging as the preferred xeno-free supplement for the expansion of mesenchymal stromal cells (MSCs) for bone tissue engineering (BTE) applications. Due to a growing demand, the ... -
The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice
Hjelmervik, Trond Ove R.; Linqvist, Anne-Karin; Petersen, Kjell; Johannesson, Martina; Stavrum, Anne-Kristin; Johansson, Åsa; Jonsson, Roland; Holmdahl, Rikard; Bolstad, Anne Isine (Peer reviewed; Journal article, 2007-09-27)The nonobese diabetic (NOD) Nss1 and Idd5 loci have been associated with sialadenitis development in mice. In this study the NOD Nss1 and Idd5 loci were backcrossed onto the healthy control strain B10.Q by using the speed ... -
Leukocyte transmigration into tissue-engineered constructs is influenced by endothelial cells through Toll-like receptor signaling
Bartaula-Brevik, Sushma; Pedersen, Torbjorn Østvik; Blois, Anna L; Papadakou, Panagiota; Finne-Wistrand, Anna; Xue, Ying; Bolstad, Anne Isine; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2014-12-20)Introduction Inflammation plays a crucial role in tissue regeneration, wound healing, and the success of tissue-engineered constructs. The aim of this study was to investigate the influence of human umbilical vein endothelial ... -
Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation
Beyer, Kathrin; Lie, Stein Atle; Bjørndal, Bodil; Berge, Rolf K.; Svardal, Asbjørn M.; Brun, Johan G.; Bolstad, Anne Isine (Journal article; Peer reviewed, 2021)Rheumatoid arthritis (RA) and periodontitis are chronic inflammatory diseases with several pathogenic pathways in common. Evidence supports an association between the diseases, but the exact underlying mechanisms behind ... -
Lymphotoxin-beta Receptor blockade reduces CXCL13 in Lacrimal Glands and improves Corneal integrity in the NOD Model of Sjögren's Syndrome
Fava, Roy A.; Kennedy, Susan M.; Wood, Sheryl G.; Bolstad, Anne Isine; Bienkowska, Jadwiga; Papandile, Adrian; Kelly, John A.; Mavragani, Clio P.; Gatumu, Margaret Karimi; Skarstein, Kathrine; Browning, Jeffrey L. (Peer reviewed; Journal article, 2011-11-01)Introduction: In Sjögren’s syndrome, keratoconjunctivitis sicca (dry eye) is associated with infiltration of lacrimal glands by leukocytes and consequent losses of tear-fluid production and the integrity of the ocular ... -
Marine ω-3, vitamin D levels, disease outcome and periodontal status in rheumatoid arthritis outpatients
Beyer, Kathrin; Lie, Stein Atle; Kjellevold, Marian; Dahl, Lisbeth; Brun, Johan G; Bolstad, Anne Isine (Peer reviewed; Journal article, 2018-11)Objectives: Marine ω-3 fatty acids (FAs) and Vitamin D (VitD) are reportedly capable of down-regulating inflammation in rheumatoid arthritis (RA) and periodontal disease. This study was undertaken to relate marine FA and ... -
Periodontitis in patients with systemic lupus erythematosus: A nation-wide study of 1990 patients
Bolstad, Anne Isine; Sehjpal, Pria; Lie, Stein Atle; Fevang, Bjørg Tilde Svanes (Journal article; Peer reviewed, 2022)Background The aim of this study was to examine the association between systemic lupus erythematosus (SLE) and periodontitis in Norway during a 10-year period from 2008 through 2017. Methods In this population-based ... -
Spheroid Coculture of Human Gingiva-Derived Progenitor Cells With Endothelial Cells in Modified Platelet Lysate Hydrogels
Shanbhag, Siddharth; Elsebahy, Ahmad Rashad; Helgeland Nymark, Ellen; Suliman, Salwa; Davies, Catharina de Lange; Stavropoulos, Andreas; Bolstad, Anne Isine; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021-08-26)Cell coculture strategies can promote angiogenesis within tissue engineering constructs. This study aimed to test the angiogenic potential of human umbilical vein endothelial cells (HUVEC) cocultured with gingiva-derived ... -
Subgingival microbial profiles of Sudanese patients with aggressive periodontitis
Elabdeen, Hager Z.R.; Mustafa, Manal; Hasturk, Hatice; Klepac-Ceraj, Vanja; Ali, Raouf W.; Paster, Bruce J.; van Dyke, Thomas; Bolstad, Anne Isine (Peer reviewed; Journal article, 2014-12-09)Background and Objective: Aggressive periodontitis (AgP) is prevalent and shows a rapid course in African individuals. Although a strong focus has been placed on Aggregatibacter actinomycetemcomitans, new methods support ... -
Xeno-free spheroids of human gingiva-derived progenitor cells for bone tissue engineering
Shanbhag, Siddharth; Suliman, Salwa; Bolstad, Anne Isine; Stavropoulos, Andreas; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2020)Gingiva has been identified as a minimally invasive source of multipotent progenitor cells (GPCs) for use in bone tissue engineering (BTE). To facilitate clinical translation, it is important to characterize GPCs in xeno-free ...