Browsing Bergen Open Research Archive by Author "Brønstad, Ingeborg"
Now showing items 1-17 of 17
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Acute effect of a cod protein hydrolysate on postprandial acylated ghrelin concentration and sensations associated with appetite in healthy subjects: a double-blind crossover trial
Dale, Hanna Fjeldheim; Jensen, Caroline; Hausken, Trygve; Lied, Einar; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Hoff, Dag Arne Lihaug; Lied, Gülen Arslan (Peer reviewed; Journal article, 2019-10-22)Background: Fish protein hydrolysates are suggested to contain bioactive sequences capable of affecting metabolic pathways involved in the regulation of glucose metabolism and body weight when consumed in low doses. ... -
Assessment of markers of gut integrity and inflammation in non-celiac gluten sensitivity after a gluten free-diet
Dale, Hanna Fjeldheim; Johannessen, Julianne Cecilie Høibak; Brønstad, Ingeborg; Lied, Gülen Arslan (Journal article; Peer reviewed, 2021)Purpose: Markers for gut integrity and inflammation have received increasing interest as intestinal permeability and innate immune system activation are suggested as possible pathophysiological mechanisms in non-celiac ... -
Comparison of pre-analytical conditions for quantification of serotonin in platelet-poor plasma
Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Fiskerstrand, Torunn; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2019)Background: Reported concentrations of serotonin in platelet-poor plasma (PPP) in healthy subjects vary widely due to different pre-analytical procedures. Aim: To examine how different pre-analytical conditions affect the ... -
Effect of a cod protein hydrolysate on postprandial glucose metabolism in healthy subjects: A double-blind cross-over trial
Dale, Hanna Fjeldheim; Jensen, Caroline; Hausken, Trygve; Lied, Einar; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Hoff, Dag Arne Lihaug; Lied, Gülen Arslan (Peer reviewed; Journal article, 2018)The increased prevalence of lifestyle diseases, such as the metabolic syndrome and type 2 diabetes mellitus (T2DM), calls for more knowledge on dietary treatments targeting the specific metabolic pathways involved in these ... -
The effect of low dose marine protein hydrolysates on short-term recovery after high intensity performance cycling: A double-blinded crossover study
Mjøs, Ingunn; Thorsen, Einar; Hausken, Trygve; Lied, Einar; Nilsen, Roy Miodini; Brønstad, Ingeborg; Edvardsen, Elisabeth; Frisk, Bente (Peer reviewed; Journal article, 2019)Background: Knowledge of the effect of marine protein hydrolysate (MPH) supplementation to promote recovery after high intensity performance training is scarce. The aim of this study was to examine the effect of MPH ... -
The effect of supplementation with low doses of a cod protein hydrolysate on satiety hormones and inflammatory biomarkers in adults with metabolic syndrome: A randomized, double-blind study
Jensen, Caroline; Dale, Hanna Fjeldheim; Hausken, Trygve; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Lied, Gülen Arslan; Hoff, Dag Arne Lihaug (Journal article; Peer reviewed, 2020-11)Metabolic syndrome (MetS) is characterised by metabolic abnormalities that increase the risk of developing type 2 diabetes mellitus and cardiovascular disease. Altered levels of circulating ghrelin, several adipokines and ... -
Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia
Brønstad, Ingeborg; Breivik, Lars Ertesvåg; Methlie, Paal; Wolff, Anette Susanne Bøe; Bratland, Eirik; Nermoen, Ingrid; Løvås, Kristian; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2014)In about 95% of cases, congenital adrenal hyperplasia (CAH) is caused by mutations in CYP21A2 gene encoding steroid 21-hydroxylase (21OH). Recently, we have reported four novel CYP21A2 variants in the Norwegian population ... -
Genome-wide copy number variation (CNV) in patients with autoimmune Addison’s disease
Brønstad, Ingeborg; Wolff, Anette S. B.; Løvås, Kristian; Knappskog, Per; Husebye, Eystein Sverre (Peer reviewed; Journal article, 2011-08-18)Background: Addison’s disease (AD) is caused by an autoimmune destruction of the adrenal cortex. The pathogenesis is multi-factorial, involving genetic components and hitherto unknown environmental factors. The aim of the ... -
Intestinal barrier integrity in anorexia nervosa (a pilot study)
Kleppe, Malin M.; Brønstad, Ingeborg; Lied, Gülen Arslan; Danielsen, Yngvild Sørebø; Rekkedal, Guro Årdal; Kessler, Ute (Journal article; Peer reviewed, 2022)Objective There is no conclusive evidence for involvement of intestinal barrier alteration in the etiology of anorexia nervosa (AN). The aims of this pilot study were to identify serum markers of intestinal barrier integrity ... -
Plasma levels of guanylins are reduced in patients with Crohn’s disease
Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Tronstad, Rune Rose; Dizdar, Vernesa; Nylund, Kim; Hanevik, Kurt; Hausken, Trygve; Gilja, Odd Helge; Fiskerstrand, Torunn (Journal article; Peer reviewed, 2020)Background: Guanylin (GN) and uroguanylin (UGN) are endogenous ligands for the intestinal receptor guanylate cyclase C (GC-C), an important regulator of intestinal fluid homeostasis. Gene expression and protein levels of ... -
Prolonged intestinal transit and diarrhea in patients with an activating GUCY2C mutation
Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Gilja, Odd Helge; Tronstad, Rune Rose; Sangnes, Dag André; Nortvedt, Ragnar; Hausken, Trygve; Dimcevski, Georg Gjorgji; Fiskerstrand, Torunn; Nylund, Kim (Peer reviewed; Journal article, 2017)Introduction: Increased intestinal hydration by activation of the epithelial enzyme linked receptor guanylate cyclase C (GC-C) is a pharmacological principle for treating constipation. Activating mutations in the GUCY2C ... -
A psychological symptom based machine learning model for clinical evaluation of irritable bowel syndrome
Haleem, Noman; Lundervold, Astri J.; Lied, Gülen Arslan; Randulff Hillestad, Eline Margrethe; Bjorkevoll, Maja; Bjørsvik, Ben René; Teige, Erica; Brønstad, Ingeborg; Steinsvik, Elisabeth Kjelsvik; Nagaraja, Bharath Halandur; Hausken, Trygve; Jacobsen, Birgitte Berentsen; Lundervold, Arvid (Journal article; Peer reviewed, 2023)Background: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by recurrent abdominal pain associated with alterations in stool form and/or stool frequency. Co-morbidities such ... -
Reduced Plasma Guanylin Levels Following Enterotoxigenic Escherichia coli-Induced Diarrhea
Brønstad, Ingeborg; Volkmann, Hilde Løland Von; Sakkestad, Sunniva Todnem; Steinsland, Hans; Hanevik, Kurt (Journal article; Peer reviewed, 2023)The intestinal peptide hormones guanylin (GN) and uroguanylin (UGN) interact with the epithelial cell receptor guanylate cyclase C to regulate fluid homeostasis. Some enterotoxigenic Escherichia coli (ETEC) produce heat-stable ... -
Study protocol of the Bergen brain-gut-microbiota-axis study: A prospective case-report characterization and dietary intervention study to evaluate the effects of microbiota alterations on cognition and anatomical and functional brain connectivity in patients with irritable bowel syndrome
Berentsen, Birgitte; Nagaraja, Bharath Halandur; Teige, Erica Persson; Lied, Gülen Arslan; Lundervold, Astri; Lundervold, Katarina; Steinsvik, Elisabeth Kjelsvik; Hillestad, Eline Margrete Randulff; Valeur, Jørgen; Brønstad, Ingeborg; Gilja, Odd Helge; Osnes, Berge; Hatlebakk, Jan Gunnar; Haász, Judit; Labus, Jennifer; Gupta, Arpana; Mayer, Emeran; Benitez-Páez, Alfonso; Sanz, Yolanda; Lundervold, Arvid; Hausken, Trygve (Journal article; Peer reviewed, 2020-09)Introduction: Irritable bowel syndrome (IBS) is a common clinical label for medically unexplained gastrointestinal (GI) symptoms, recently described as a disturbance of the brain-gut-microbiota (BGM) axis. To gain a ... -
Supplementation with cod protein hydrolysate in older adults: A dose range cross-over study
Jensen, Caroline; Dale, Hanna Fjeldheim; Hausken, Trygve; Lied, Einar; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Lied, Gülen Arslan; Hoff, Dag Arne Lihaug (Peer reviewed; Journal article, 2019)A large proportion of older adults are affected by impaired glucose metabolism. Previous studies with fish protein have reported improved glucose regulation in healthy adults, but the evidence in older adults is limited. ... -
Supplementation with Low Doses of a Cod Protein Hydrolysate on Glucose Regulation and Lipid Metabolism in Adults with Metabolic Syndrome: A Randomized, Double-Blind Study
Jensen, Caroline; Dale, Hanna Fjeldheim; Hausken, Trygve; Hatlebakk, Jan Gunnar; Brønstad, Ingeborg; Lied, Gülen Arslan; Hoff, Dag Arne Lihaug (Journal article; Peer reviewed, 2020)The risk of cardiovascular diseases and type 2 diabetes mellitus are increased in subjects with metabolic syndrome (MetS), and hydrolyzed fish protein may have favorable effects on metabolic health. Here, we investigated ... -
UCP1 induction during recruitment of Brown Adipocytes in White Adipose tissue is dependent on Cyclooxygenase activity
Madsen, Lise; Pedersen, Lone M.; Lillefosse, Haldis Haukaas; Fjære, Even; Brønstad, Ingeborg; Hao, Qin; Petersen, Rasmus Koefoed; Hallenborg, Philip; Ma, Tao; De Matteis, Rita; Araujo, Pedro; Mercader, Josep; Bonet, M. Luisa; Hansen, Jacob B.; Cannon, Barbara; Nedergaard, Jan; Wang, Jun; Cinti, Saverio; Voshol, Peter; Døskeland, Stein Ove; Kristiansen, Karsten (Peer reviewed; Journal article, 2010-06-30)Background The uncoupling protein 1 (UCP1) is a hallmark of brown adipocytes and pivotal for cold- and diet-induced thermogenesis. Methodology/Principal Findings Here we report that cyclooxygenase (COX) activity and ...