• The FLUKA Monte Carlo code coupled with an OER model for biologically weighted dose calculations in proton therapy of hypoxic tumors 

      Dahle, Tordis Johnsen; Rusten, Espen; Stokkevåg, Camilla Hanquist; Silvoniemi, Antti; Mairani, Andrea; Fjæra, Lars Fredrik; Rørvik, Eivind; Henjum, Helge; Wright, Pauliina; Boer, Camilla Grindeland; Forsback, Sarita; Minn, Heikki; Malinen, Eirik; Ytre-Hauge, Kristian (Journal article; Peer reviewed, 2020)
      Introduction The increased radioresistance of hypoxic cells compared to well-oxygenated cells is quantified by the oxygen enhancement ratio (OER). In this study we created a FLUKA Monte Carlo based tool for inclusion of ...
    • Inter-patient variations in relative biological efectiveness for craniospinal irradiation with protons 

      Ytre-Hauge, Kristian; Fjæra, Lars Fredrik; Rørvik, Eivind; Dahle, Tordis Johnsen; Dale, Jon Espen; Pilskog, Sara; Stokkevåg, Camilla Hanquist (Journal article; Peer reviewed, 2020)
      Cranio-spinal irradiation (CSI) using protons has dosimetric advantages compared to photons and is expected to reduce risk of adverse effects. The proton relative biological effectiveness (RBE) varies with linear energy ...
    • The Organ Sparing Potential of Different Biological Optimization Strategies in Proton Therapy 

      Henjum, Helge; Dahle, Tordis Johnsen; Fjæra, Lars Fredrik; Rørvik, Eivind; Pilskog, Sara Margareta Cecilia; Stokkevåg, Camilla H.; Mairani, Andrea; Ytre-Hauge, Kristian Smeland (Journal article; Peer reviewed, 2021)
      Purpose Variable relative biological effectiveness (RBE) models allow for differences in linear energy transfer (LET), physical dose, and tissue type to be accounted for when quantifying and optimizing the biological ...
    • Performance Evaluation of a Small-Animal PET/CT System 

      Dahle, Tordis Johnsen (Master thesis, 2014-06-02)
      This master project is the first vendor-independent performance evaluation of the new nanoScan PET/CT system at the University of Bergen. A comprehensive performance evaluation of a novel scanner is very important, ...
    • Studies of the Relative Biological Effectiveness and Biological Dose in Proton and Carbon Ion Therapy 

      Dahle, Tordis Johnsen (Doctoral thesis, 2020-04-28)
      Protons and heavier ions have an increased relative biological effectiveness (RBE) compared to photons. While variable RBE models are applied clinically in carbon ion therapy, the RBE in proton therapy is accounted for ...