Blar i Bergen Open Research Archive på forfatter "Fronton, Ludivine"
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Interstitial IgG antibody pharmacokinetics assessed by combined in vivo- and physiologically-based pharmacokinetic modelling approaches
Eigenmann, Miro Julian; Karlsen, Tine Veronica; Krippendorff, Ben-Fillippo; Tenstad, Olav; Fronton, Ludivine; Otteneder, Michael B.; Wiig, Helge (Peer reviewed; Journal article, 2017-12)For most therapeutic antibodies, the interstitium is the target space. Although experimental methods for measuring antibody pharmacokinetics (PK) in this space are not well established, thus making quantitative assessment ...