Browsing Bergen Open Research Archive by Author "Grong, Ketil"
Now showing items 1-10 of 10
-
Carvedilol-enriched cold oxygenated blood cardioplegia improves left ventricular diastolic function after weaning from cardiopulmonary bypass
Dahle, Geir Olav; Salminen, Pirjo-Riitta; Moen, Christian Arvei; Eliassen, Finn; Nygreen, Else Loholdt; Kytö, Ville; Saukko, Pekka; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2016-08)Objectives: To investigate whether adding carvedilol, a nonselective β- and selective α1-receptor blocking agent with antioxidant properties, to oxygenated blood cardioplegia improves myocardial function after weaning from ... -
Esmolol added in repeated, cold, oxygenated blood cardioplegia improves myocardial function after cardiopulmonary bypass
Dahle, Geir Olav; Salminen, Pirjo-Riitta; Moen, Christian Arvei; Eliassen, Finn; Jonassen, Anne K.; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2015-06)Objective: This study investigated if the β-receptor blocking agent esmolol, added to standard oxygenated blood cardioplegia, improved myocardial function after weaning from bypass. Design: A block-randomized, blinded ... -
The influence of acute unloading on left ventricular strain and strain rate by speckle tracking echocardiography in a porcine model
Dahle, Geir Olav; Stangeland, Lodve; Moen, Christian Arvei; Salminen, Pirjo-Riitta; Haavestad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2016)Noninvasive measurements of myocardial strain and strain rate by speckle tracking echocardiography correlate to cardiac contractile state but also to load, which may weaken their value as indices of inotropy. In a porcine ... -
Is strain by Speckle Tracking Echocardiography dependent on user controlled spatial and temporal smoothing? An experimental porcine study
Moen, Christian A.; Salminen, Pirjo-Riitta; Dahle, Geir O.; Hjertaas, Johannes J.; Grong, Ketil; Matre, Knut (Peer reviewed; Journal article, 2013-08-22)Background Speckle Tracking Echocardiography (STE) strain analysis relies on both spatial and temporal smoothing. The user is often allowed to adjust these smoothing parameters during analysis. This experimental study ... -
Left ventricular dysfunction after two hours of polarizing or depolarizing cardioplegic arrest in a porcine model
Aass, Terje; Stangeland, Lodve; Moen, Christian Arvei; Solholm, Atle; Dahle, Geir Olav; Chambers, David J.; Urban, Malte; Nesheim, Knut; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2019)Introduction: This experimental study compares myocardial function after prolonged arrest by St. Thomas’ Hospital polarizing cardioplegic solution (esmolol, adenosine, Mg2+) with depolarizing (hyperkalaemic) St. Thomas’ ... -
Long-term follow-up after surgery for atrial fibrillation with concomitant open heart surgery
Andersen, Knut Sverre; Grong, Ketil; Hoff, Per-Ivar; Waba, Alexander (Journal article; Peer reviewed, 2021)BACKGROUND Patients with atrial fibrillation and atrial flutter scheduled to undergo open heart surgery can receive ablation treatment of arrhythmogenic foci during the same intervention. Sinus rhythm is restored in the ... -
Myocardial energy metabolism and ultrastructure with polarizing and depolarizing cardioplegia in a porcine model
Aass, Terje; Stangeland, Lodve; Chambers, David J.; Hallstrõm, Seth; Rossmann, Christine; Podesser, Bruno K.; Urban, Malte; Nesheim, Knut; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2017-03-02)OBJECTIVES: This study investigated whether the novel St. Thomas’ Hospital polarizing cardioplegic solution (STH-POL) with esmolol/adenosine/magnesium offers improved myocardial protection by reducing demands for high-energy ... -
Myocardial function after polarizing versus depolarizing cardiac arrest with blood cardioplegia in a porcine model of cardiopulmonary bypass
Aass, Terje; Stangeland, Lodve; Moen, Christian Arvei; Salminen, Pirjo-Riitta; Dahle, Geir Olav; Chambers, David J.; Markou, Thomais; Eliassen, Finn; Urban, Malte; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2016)OBJECTIVES Potassium-based depolarizing St Thomas' Hospital cardioplegic solution No 2 administered as intermittent, oxygenated blood is considered as a gold standard for myocardial protection during cardiac surgery. ... -
Outcome after rewarming from accidental hypothermia by use of extracorporeal circulation
Svendsen, Øyvind Sverre; Grong, Ketil; Andersen, Knut Sverre; Husby, Paul (Peer reviewed; Journal article, 2017)Background: Accidental hypothermia with arrested circulation remains a condition associated with high mortality. In our institution, extracorporeal circulation (ECC) rewarming has been the cornerstone in treating such ... -
Reperfusion Therapy with Low-Dose Insulin or Insulin-Like Growth Factor 2; Myocardial Function and Infarct Size in a Porcine Model of Ischaemia and Reperfusion
Salminen, Pirjo-Riitta; Dahle, Geir Olav; Moen, Christian Arvei; Wergeland, Anita; Jonassen, Anne Kristin; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2014-05-19)In an open-chest porcine model, we examined whether myocardial pharmacological conditioning at the time of reperfusion with low-dose insulin or insulin-like growth factor 2 (IGF2), not affecting serum glucose levels, could ...