• AIDS-related primary central nervous system lymphoma: a Norwegian national survey 1989–2003 

      Haldorsen, Ingfrid S.; Kråkenes, Jostein; Goplen, Anne Kristin; Dunlop, Oona; Mella, Olav; Espeland, Ansgar (Peer reviewed; Journal article, 2008-08-06)
      Background: Primary central nervous system lymphoma (PCNSL) is a frequent complication in acquired immunodeficiency syndrome (AIDS). The objective of this survey was to investigate incidence, clinical features, radiological ...
    • Blood Metabolites Associate with Prognosis in Endometrial Cancer 

      Strand, Elin; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik; Jacob, Havjin; Halle, Mari Kyllesø; Hoivik, Erling A; Delvoux, Bert; Trovik, Jone; Haldorsen, Ingfrid S.; Romano, Andrea; Krakstad, Camilla (Peer reviewed; Journal article, 2019-12-14)
      Endometrial cancer has a high prevalence among post-menopausal women in developed countries. We aimed to explore whether certain metabolic patterns could be related to the characteristics of aggressive disease and poorer ...
    • Blood steroid levels predict survival in endometrial cancer and reflect tumor estrogen signaling 

      Forsse, David Erik; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik; Halle, Mari Kyllesø; Viste, Kristin; Almås, Bjørg; Bertelsen, Bjørn-Erik; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Peer reviewed; Journal article, 2020-02)
      Objective Blood-based biomarkers are attractive due to ease of sampling and standardized measurement technology, reducing obstacles to clinical implementation. The objective of this study was to evaluate a clinically ...
    • Cancer awareness in the general population varies with sex, age and media coverage: A population-based survey with focus on gynecologic cancers 

      Fonnes, Tina; Telle, Ingrid Ovidia Moe; Forsse, David Erik; Falck, Runa; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)
      Objectives There is a need for more knowledge about the public awareness and attitudes towards gynecologic cancers. We employed a research-purpose population-based citizen panel to assess how often people recall gynecologic ...
    • Comparing screening outcomes for digital breast tomosynthesis and digital mammography by automated breast density in a randomized controlled trial: Results from the to-be trial 

      Moshina, Nataliia; Aase, Hildegunn Siv; Danielsen, Anders Skyrud; Haldorsen, Ingfrid S.; Lee, Christoph I.; Zackrisson, Sophia; Hofvind, Solveig (Journal article; Peer reviewed, 2020)
      Background: Digital breast tomosynthesis (DBT) is considered superior to digital mammography (DM) for women with dense breasts. Purpose: To identify differences in screening outcomes, including rates of recall, ...
    • Development of prediction models for lymph node metastasis in endometrioid endometrial carcinoma 

      Berg, Hege Fredriksen; Ju, Zhenlin; Myrvold, Madeleine; Fasmer, Kristine Eldevik; Halle, Mari Kyllesø; Høivik, Erling Andre; Westin, Shannon; Trovik, Jone; Haldorsen, Ingfrid S.; Mills, Gordon B.; Krakstad, Camilla; Werner, Henrica Maria Johanna (Journal article; Peer reviewed, 2020-02-10)
      Background In endometrioid endometrial cancer (EEC), current clinical algorithms do not accurately predict patients with lymph node metastasis (LNM), leading to both under- and over-treatment. We aimed to develop models ...
    • Diagnostic accuracy of transabdominal ultrasound in chronic pancreatitis 

      Engjom, Trond; Sangnes, Dag André; Havre, Roald Flesland; Erchinger, Friedemann Georg; Pham, Khanh Do-Cong; Haldorsen, Ingfrid S.; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2017-04)
      The performance of transabdominal ultrasound (US) in chronic pancreatitis (CP) following the advances in US technology made during recent decades has not been explored. Our aim in this prospective study was to evaluate the ...
    • Endorectal ultrasonography, strain elastography and MRI differentiation of rectal adenomas and adenocarcinomas. 

      Waage, Jo Erling Riise; Leh, Sabine Maria; Røsler, Cornelia; Pfeffer, Frank; Bach, Simon; Havre, Roald Flesland; Haldorsen, Ingfrid S.; Ødegaard, Svein; Baatrup, Gunnar (Peer reviewed; Journal article, 2015-02)
      Aim Strain elastography is a method for recording tissue hardness. Strain in different areas may be compared using strain ratio (SR). The aims of this study were to validate a previously proposed SR cut-off value of 1.25 ...
    • Feasibility and utility of MRI and dynamic 18F-FDG-PET in an orthotopic organoid-based patient-derived mouse model of endometrial cancer 

      Espedal, Heidi; Berg, Hege Fredriksen; Fonnes, Tina; Fasmer, Kristine Eldevik; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021)
      Background: Pelvic magnetic resonance imaging (MRI) and whole-body positron emission tomography-computed tomography (PET-CT) play an important role at primary diagnostic work-up and in detecting recurrent disease in ...
    • HER2 expression patterns in paired primary and metastatic endometrial cancer lesions 

      Halle, Mari Kyllesø; Tangen, Ingvild Løberg; Berg, Hege Fredriksen; Hoivik, Erling A; Mauland, Karen Klepsland; Kusonmano, Kanthida; Berg, Anna; Hurtado, Antoni; Kalland, Karl-Henning; Øyan, Anne Margrete; Stefansson, Ingunn; Vintermyr, Olav Karsten; Werner, Henrica Maria Johanna; Haldorsen, Ingfrid S.; Trovik, Jone; Salvesen, Helga Birgitte; Krakstad, Camilla (Peer reviewed; Journal article, 2017-11-23)
      Background: Despite successful implementation of drugs targeting the human epidermal growth factor receptor 2 (HER2) receptor in breast and gastric cancers, the potential of HER2 as a therapeutic target in other cancers ...
    • High degree of heterogeneity of PD-L1 and PD-1 from primary to metastatic endometrial cancer 

      Engerud, Hilde Renate; Berg, Hege Fredriksen; Myrvold, Madeleine; Halle, Mari Kyllesø; Bjørge, Line; Haldorsen, Ingfrid S.; Høivik, Erling Andre; Trovik, Jone; Krakstad, Camilla (Journal article; Peer reviewed, 2020)
      Objective PD-L1 and PD-1 are predictive markers for immunotherapy and increasingly relevant in endometrial cancer. The reported fraction of positive primary tumors has been inconsistent. We investigated the expression of ...
    • High visceral fat percentage is associated with poor outcome in endometrial cancer 

      Mauland, Karen Klepsland; Eng, Øyvin Andre Solberg; Ytre-Hauge, Sigmund; Tangen, Ingvild Løberg; Berg, Anna; Salvesen, Helga; Salvesen, Øyvind; Krakstad, Camilla; Trovik, Jone; Høivik, Erling Andre; Werner, Henrica Maria Johanna; Mellgren, Gunnar; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2017-10-19)
      Despite evidence of increased endometrial cancer (EC) risk in obese women, the impact of obesity on clinical and histological phenotype is poorly understood. This study explored abdominal fat volumes and fat distribution ...
    • Imaging of preclinical endometrial cancer models for monitoring tumor progression and response to targeted therapy 

      Espedal, Heidi; Fonnes, Tina; Fasmer, Kristine Eldevik; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2019-11-27)
      Endometrial cancer is the most common gynecologic malignancy in industrialized countries. Most patients are cured by surgery; however, about 15% of the patients develop recurrence with limited treatment options. Patient-derived ...
    • Impact of body mass index and fat distribution on sex steroid levels in endometrial carcinoma: A retrospective study 

      van Weelden, Willem Jan; Fasmer, Kristine Eldevik; Tangen, Ingvild Løberg; IntHout, Joanna; Abbink, Karin; van Herwaarden, Antonius E.; Krakstad, Camilla; Massuger, Leon F.A.G.; Haldorsen, Ingfrid S.; Pijnenborg, Johanna M.A. (Peer reviewed; Journal article, 2019-06-07)
      Background Obesity is an important cause of multiple cancer types, amongst which endometrial cancer (EC). The relation between obesity and cancer is complicated and involves alterations in insulin metabolism, response to ...
    • Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas 

      Haldorsen, Ingfrid S.; Stefansson, Ingunn; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Trovik, Jone; Taxt, Torfinn; Akslen, Lars A.; Salvesen, Helga Birgitte (Peer reviewed; Journal article, 2014)
      Background: We aimed to study the angiogenic profile based on histomorphological markers in endometrial carcinomas in relation to imaging parameters obtained from preoperative dynamic contrast-enhanced magnetic resonance ...
    • Maintained survival outcome after reducing lymphadenectomy rates and optimizing adjuvant treatment in endometrial cancer 

      Forsse, David Erik; Berg, Hege Fredriksen; Bozickovic, Olivera; Engerud, Hilde Renate; Halle, Mari Kyllesø; Høivik, Erling Andre; Woie, Kathrine; Werner, Henrica Maria Johanna; Haldorsen, Ingfrid S.; Trovik, Jone; Krakstad, Camilla (Journal article; Peer reviewed, 2020)
      Objective: Main controversies in endometrial cancer treatment include the role of lymphadenectomy and optimal adjuvant treatment. We assessed clinical outcome in a population-based endometrial cancer cohort in relation to ...
    • An mri-based radiomic prognostic index predicts poor outcome and specific genetic alterations in endometrial cancer 

      Jacob, Havjin; Dybvik, Julie Andrea; Ytre-Hauge, Sigmund; Fasmer, Kristine E.; Høivik, Erling Andre; Trovik, Jone; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021)
      Integrative tumor characterization linking radiomic profiles to corresponding gene expression profiles has the potential to identify specific genetic alterations based on non-invasive radiomic profiling in cancer. The aim ...
    • Multimodal Imaging of Orthotopic Mouse Model of Endometrial Carcinoma 

      Haldorsen, Ingfrid S.; Popa, Mihaela Lucia; Fonnes, Tina; Brekke, Njål; Kopperud, Reidun Kristin; Visser, Nicole C.; Rygh, Cecilie Brekke; Pavlin, Tina; Salvesen, Helga Birgitte; McCormack, Emmet; Krakstad, Camilla (Peer reviewed; Journal article, 2015-08-07)
      Background: Orthotopic endometrial cancer models provide a unique tool for studies of tumour growth and metastatic spread. Novel preclinical imaging methods also have the potential to quantify functional tumour characteristics ...
    • Plasma growth differentiation factor-15 is an independent marker for aggressive disease in endometrial cancer 

      Engerud, Hilde Renate; Hope, Kirsten Øvergaard; Berg, Hege Fredriksen; Fasmer, Kristine Eldevik; Tangen, Ingvild Løberg; Haldorsen, Ingfrid S.; Trovik, Jone; Krakstad, Camilla (Peer reviewed; Journal article, 2019)
      Objective: Better biomarkers are needed in order to identify patients with endometrial carcinoma at risk of recurrence and who may profit from a more aggressive treatment regimen. Our objective was to explore the applicability ...
    • Poor outcome in hypoxic endometrial carcinoma is related to vascular density 

      Reijnen, Casper; van Weelden, Willem Jan; Arts, Martijn S.J.P.; Peters, Johan P.; Rijken, Paul F.; van de Vijver, Koen; Santacana, Maria; Bronsert, Peter; Bulten, Johan; Hirschfeld, Marc; Colas, Eva; Gil-Moreno, Antonio; Reques, Armando; Mancebo, Gemma; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S.; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Minar, Lubos; Jandakova, Eva; Snijders, Marc P.L.M.; van den Berg-van Erp, Saskia; Küsters-Vandevelde, Heidi V.N.; Matias-Guiu, Xavier; Amant, Frederic; Massuger, Leon F.A.G.; Bussink, Johan; Pijnenborg, Johanna M.A. (Peer reviewed; Journal article, 2019-04-23)
      Background Identification of endometrial carcinoma (EC) patients at high risk of recurrence is lacking. In this study, the prognostic role of hypoxia and angiogenesis was investigated in EC patients. Methods Tumour slides ...