• Brain reactivity during aggressive response in women with premenstrual dysphoric disorder treated with a selective progesterone receptor modulator 

      Kaltsouni, Elisavet; Fisher, Patrick M.; Dubol, Manon; Hustad, Steinar; Lanzenberger, Rupert; Frokjaer, Vibe G.; Wikström, Johan; Comasco, Erika; Sundström-Poromaa, Inger (Journal article; Peer reviewed, 2021)
      Premenstrual dysphoric disorder (PMDD) is a psychiatric condition characterized by late luteal phase affective, cognitive, and physical impairment. The disorder causes significant suffering in about 5% of women in their ...
    • Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels 

      Triebner, Kai; Johannessen, Ane; Svanes, Cecilie; Leynaert, Bénédicte; Benediktsdóttir, Bryndís; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Lindberg, Eva; Moratalla, Jesús Martínez; Agirre, Nerea Muniozguren; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Hustad, Steinar; Rodríguez, Francisco J.; Gomez Real, Francisco (Journal article; Peer reviewed, 2020)
      Objective Most women live to experience menopause and will spend 4–8 years transitioning from fertile age to full menstrual stop. Biologically, reproductive ageing is a continuous process, but by convention, it is defined ...
    • Low serum DHEA-S is associated with impaired lung function in women 

      Triebner, Kai; Pesce, Giancarlo; van der Plaat, Diana A.; Courbon, Dominique; Hustad, Steinar; Sigsgaard, Torben; Nowak, Dennis; Heinrich, Joachim; Antó, Jósep Maria; Dorado-Arenas, Sandra; Martínez-Moratalla, Jesús; Gullon-Blanco, Jose A.; Sánchez-Ramos, José L.; Rahérison, Chantal; Pin, Isabelle; Demoly, Pascal; Toren, Kjell; Forsberg, Bertil; Lindberg, Eva; Zemp, Elisabeth; Jogi, Rain; Probst-Hensch, Nicole; Dharmage, Shyamali C.; Jarvis, Debbie; Garcia-Aymerich, Judith; Marcon, Alessandro; Gómez-Real, Francisco; Leynaert, Bénédicte; Gislason, Thorarinn (Journal article; Peer reviewed, 2020)
      Background Emerging evidence suggests that androgens and estrogens have a role in respiratory health, but it is largely unknown whether levels of these hormones can affect lung function in adults from the general population. ...
    • Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen 

      Helland, Thomas; Naume, Bjørn; Hustad, Steinar; Bifulco, Ersilia; Kvaløy, Jan Terje; Sætersdal, Anna Barbro; Synnestvedt, Marit; Lende, Tone Hoel; Gilje, Bjørnar; Mjaaland, Ingvil; Weyde, Kjetil; Blix, Egil Støre; Wiedswang, Gro; Borgen, Elin; Hertz, Daniel Louis; Janssen, Emiel; Mellgren, Gunnar; Søiland, Håvard (Journal article; Peer reviewed, 2021)
      Low steady‐state levels of active tamoxifen metabolites have been associated with inferior treatment outcomes. In this retrospective analysis of 406 estrogen receptor‐positive breast cancer (BC) patients receiving adjuvant ...
    • Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells 

      Sepponen, Kirsi; Lundin, Karolina; Yohannes, Dawit A.; Vuoristo, Sanna; Balboa, Diego; Poutanen, Matti; Ohlsson, Claes; Hustad, Steinar; Bifulco, Ersilia; Paloviita, Pauliina; Otonkoski, Timo; Ritvos, Olli; Sainio, Kirsi; Tapanainen, Juha S.; Tuuri, Timo (Journal article; Peer reviewed, 2022)
      Nuclear receptor subfamily 5 group A member 1 (NR5A1) encodes steroidogenic factor 1 (SF1), a key regulatory factor that determines gonadal development and coordinates endocrine functions. Here, we have established a stem ...
    • Ultraviolet radiation as a predictor of sex hormone levels in postmenopausal women: A European multi-center study (ECRHS) 

      Triebner, Kai; Bifulco, Ersilia; Barrera-Gómez, Jose; Basagaña, Xavier; Benediktsdóttir, Bryndís; Forsberg, Bertil; Franklin, Karl A.; Garcia-Larsen, Vanessa; Leynaert, Bénédicte; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren-Agirre, Nerea; Pin, Isabelle; Raherison, Chantal; Pereira-Vega, Antonio; Schlünssen, Vivi; Valentin, Antonia; Hustad, Steinar; Real, Francisco Gomez; Dadvand, Payam (Journal article; Peer reviewed, 2021)
      Background Solar ultraviolet radiation (UVR) affects the body through pathways that exhibit positive as well as negative health effects such as immunoregulation and vitamin D production. Different vitamin D metabolites ...