Blar i Bergen Open Research Archive på forfatter "Jarvis, Deborah"
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Association of adult lung function with accelerated biological aging
Rezwan, Faizal I; Imboden, Medea; Amaral, André F.S.; Wielscher, Matthias; Jeong, Ayoung; Triebner, Kai; Gomez Real, Francisco; Jarvelin, Marjo-Riitta; Jarvis, Deborah; Probst-Hensch, Nicole M; Holloway, John W (Journal article; Peer reviewed, 2020)Lung function, strongly associated with morbidity and mortality, decreases with age. This study examines whether poor adult lung function is associated with age accelerations (AAs). DNA methylation (DNAm) based AAs, lifespan ... -
Atopy Modifies the Association Between Inhaled Corticosteroid Use and Lung Function Decline in Patients with Asthma
Marcon, Alessandro; Marchetti, P; Anto, J.M.; Cazzoletti, Lucia; Cerveri, Isa; Corsico, Angelo; Ferreira, D.S.; Garcia-Aymerich, Judith; Gislason, David; Heinrich, Joachim; Jögi, Rain; Johannessen, Ane; Leynaert, Benedicte; Malinovschi, Andrei; Pin, Isabelle; Probst-Hensch, Nicole; Weyler, Joost; Janson, Christer; Jarvis, Deborah; Accordini, Simone (Peer reviewed; Journal article, 2020)Background: Inhaled corticosteroids (ICSs) are the mainstay of asthma treatment, but response to medication is variable. Patients with allergic inflammation generally show a better short-term response to ICSs; however, ... -
Being overweight in childhood, puberty, or early adulthood: Changing asthma risk in the next generation?
Johannessen, Ane; Lønnebotn, Marianne; Calciano, Lucia; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali; Franklin, Karl A.; Gíslason, Þórarinn; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Jõgi, Rain; Kim, Jeong-Lim; Kirkeleit, Jorunn; Lodge, Caroline; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Nilsen, Roy Miodini; Pereira-Vega, Antonio; Gomez Real, Francisco; Schlünssen, Vivi; Accordini, Simone; Svanes, Cecilie (Peer reviewed; Journal article, 2020-03)Background Overweight status and asthma have increased during the last decades. Being overweight is a known risk factor for asthma, but it is not known whether it might also increase asthma risk in the next generation. ... -
Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study
Peralta, Gabriela P.; Marcon, Alessandro; Carsin, Anne-Elie; Abramson, Michael J.; Accordini, Simone; Amaral, André F.S.; Antó, Josep Maria; Bowatte, Gayan; Burney, Peter; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali C.; Forsberg, Bertil; Fuertes, Elaine; Garcia-Larsen, Vanessa; Gislason, Thorarinn; Gullón, José-Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Janson, Christer; Jõgi, Rain; Johannessen, Ane; Leynaert, Bénédicte; Rovira, Jesús Martínez-Moratalla; Nowak, Dennis; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Sigsgaard, Torben; Siroux, Valérie; Squillacioti, Giulia; Urrutia, Isabel; Weyler, Joost; Zock, Jan-Paul; Garcia-Aymerich, Judith (Journal article; Peer reviewed, 2020)Background Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function trajectories during adulthood ... -
Body silhouettes as a tool to reflect obesity in the past
Lønnebotn, Marianne; Svanes, Cecilie; Igland, Jannicke; Franklin, Karl A.; Accordini, Simone; Benediktsdóttir, Bryndís; Bentohuami, Hayat; Blanco, José Antonio Gullón; Bono, Roberto; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali; Dorado Arenas, Sandra; Garcia, Judith; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Leynaert, Bénédicte; Martinez-Moratalla, Jesús; Nowak, Dennis; Pin, Isabelle; Raherison-Semjen, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Dratva, Julia; Gomez Real, Francisco (Peer reviewed; Journal article, 2018-04-25)Life course data on obesity may enrich the quality of epidemiologic studies analysing health consequences of obesity. However, achieving such data may require substantial resources. We investigated the use of body silhouettes ... -
Bronchodilator response and lung function decline: Associations with exhaled nitric oxide with regard to sex and smoking status
Nerpin, Elisabet; Ferreira, Diogenes Seraphim; Weyler, Joost; Schlunnsen, Vivi; Jogi, Rain; Raherison, Chantal; Gislasson, Thorainn; Demoly, Pascal; Heinrich, Joachim; Nowak, Dennis; Corsico, Angelo; Accordini, Simone; Marcon, Alessandro; Squillacioti, Giulia; Olivieri, Mario; Nielsen, Rune; Johannessen, Ane; Real, Francisco Gomez; Garcia-Aymerich, Judith; Urrutia, Isabel; Pereira-Vega, Antonio; Gullón, José-Antonio; Olin, Anna-Carin; Forsberg, Bertil; Emilsson, Össur Ingi; Pin, Isabelle; Jarvis, Deborah; Janson, Christer; Malinovschi, Andrei (Journal article; Peer reviewed, 2021)Background Fractional exhaled nitric oxide (FeNO) is a marker of type-2 inflammation used both to support diagnosis of asthma and follow up asthma patients. The associations of FeNO with lung function decline and ... -
The coexistence of asthma and COPD: risk factors, clinical history and lung function trajectories
Marcon, Alessandro; Locatelli, Francesca; Dharmage, Shyamali C.; Svanes, Cecilie; Heinrich, Joachim; Leynaert, Bénédicte; Burney, Peter; Corsico, Angelo; Caliskan, Gulser; Calciano, Lucia; Gislason, Thorarinn; Janson, Christer; Jarvis, Deborah; Jõgi, Rain; Lytras, Theodore; Malinovschi, Andrei; Probst-Hensch, Nicole; Toren, Kjell; Casas, Lidia; Verlato, Giuseppe; Garcia-Aymerich, Judith; Accordini, Simone (Journal article; Peer reviewed, 2021)Patients with concomitant features of asthma and chronic obstructive pulmonary disease (COPD) have a heavy disease burden. Using data collected prospectively in the European Community Respiratory Health Survey, we ... -
Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels
Triebner, Kai; Johannessen, Ane; Svanes, Cecilie; Leynaert, Bénédicte; Benediktsdóttir, Bryndís; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Lindberg, Eva; Moratalla, Jesús Martínez; Agirre, Nerea Muniozguren; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Hustad, Steinar; Rodríguez, Francisco J.; Gomez Real, Francisco (Journal article; Peer reviewed, 2020)Objective Most women live to experience menopause and will spend 4–8 years transitioning from fertile age to full menstrual stop. Biologically, reproductive ageing is a continuous process, but by convention, it is defined ... -
Determinants of fractional exhaled nitric oxide in healthy men and women from the European Community Respiratory Health Survey III
Nerpin, Elisabet; Olivieri, Mario; Gislason, Thorainn; Olin, Anna C.; Nielsen, Rune; Johannessen, Ane; Ferreira, Diogenes S.; Marcon, Alessandro; Cazzoletti, Lucia; Accordini, Simone; Pin, Isabelle; Corsico, Angelo; Demoly, Pascal; Weyler, Joost; Nowak, Dennis; Jõgi, Rain; Forsberg, Bertil; Zock, Jan P.; Sigsgaard, Torben; Heinric, Joachim; Bono, Roberto; Leynaert, Bénédicte; Jarvis, Deborah; Janson, Christer; Malinovschi, Anderi (Peer reviewed; Journal article, 2019)Introduction: The fractional exhaled nitric oxide (FENO ) is a marker for type 2 inflammation used in diagnostics and management of asthma. In order to use FENO as a reliable biomarker, it is important to investigate factors ... -
Early life exposures contributing to accelerated lung function decline in adulthood – a follow-up study of 11,000 adults from the general population
Kirkeleit, Jorunn; Riise, Trond; Wielscher, Mathias; Accordini, Simone; Carsin, Anne-Elie; Dratva, Julie; Franklin, Karl A.; Garcia-Aymerich, Judith; Jarvis, Deborah; Leynaert, Benedicte; Lodge, Caroline J.; Gomez Real, Francisco; Schlünssen, Vivi; Corsico, Angelo Guido; Heinrich, Joachim; Holm, Matthias; Janson, Christer; Benediktsdóttir, Bryndís; Jogi, Rain; Dharmage, Shyamali C.; Jarvelin, Marjo-Riitta; Svanes, Cecilie (Journal article; Peer reviewed, 2023)Background We aimed to assess whether exposure to risk factors in early life from conception to puberty continue to contribute to lung function decline later in life by using a pooled cohort comprising approx. 11,000 adults ... -
Epigenome-wide association of father's smoking with offspring DNA methylation: a hypothesis-generating study
Knudsen, Gerd Toril Mørkve; Rezwan, FI; Johannessen, Ane; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Gomez Real, Francisco; Krauss-Etschmann, Susanne; Patil, Viswanath; Jarvis, Deborah; Arshad, SH; Holloway, John W; Svanes, Cecilie (Peer reviewed; Journal article, 2019)Epidemiological studies suggest that father’s smoking might influence their future children’s health, but few studies have addressed whether paternal line effects might be related to altered DNA methylation patterns in the ... -
European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
Budu-Aggrey, Ashley; Kilanowski, Anna; Sobczyk, Maria K.; Shringarpure, Suyash S.; Mitchell, Ruth; Reis, Kadri; Reigo, Anu; Mägi, Reedik; Nelis, Mari; Tanaka, Nao; Brumpton, Ben Michael; Thomas, Laurent Francois; Sole-Navais, Pol; Flatley, Christopher; Espuela-Ortiz, Antonio; Herrera-Luis, Esther; Lominchar, Jesus V. T.; Bork-Jensen, Jette; Marenholz, Ingo; Arnau-Soler, Aleix; Jeong, Ayoung; Fawcett, Katherine A.; Baurecht, Hansjorg; Rodriguez, Elke; Alves, Alexessander Couto; Kumar, Ashish; Sleiman, Patrick M.; Chang, Xiao; Medina-Gomez, Carolina; Hu, Chen; Xu, Cheng-jian; Qi, Cancan; El-Heis, Sarah; Titcombe, Philip; Antoun, Elie; Fadista, João; Wang, Carol A.; Thiering, Elisabeth; Wu, Baojun; Kress, Sara; Kothalawala, Dilini M.; Kadalayil, Latha; Duan, Jiasong; Zhang, Hongmei; Hadebe, Sabelo; Hoffmann, Thomas; Jorgenson, Eric; Choquet, Hélène; Risch, Neil; Njølstad, Pål Rasmus; Andreassen, Ole; Johansson, Stefan; Almqvist, Catarina; Gong, Tong; Ullemar, Vilhelmina; Karlsson, Robert; Magnusson, Patrik K. E.; Szwajda, Agnieszka; Burchard, Esteban G.; Thyssen, Jacob P.; Hansen, Torben; Kårhus, Line L.; Dantoft, Thomas M.; Jeanrenaud, Alexander C.S.N.; Ghauri, Ahla; Arnold, Andreas; Homuth, Georg; Lau, Susanne; Nöthen, Markus M.; Hübner, Norbert; Imboden, Medea; Visconti, Alessia; Falchi, Mario; Bataille, Veronique; Hysi, Pirro; Ballardini, Natalia; Boomsma, Dorret I.; Hottenga, Jouke J.; Müller-Nurasyid, Martina; Ahluwalia, Tarunveer S.; Stokholm, Jakob; Chawes, Bo; Schoos, Ann-Marie M.; Esplugues, Ana; Bustamante, Mariona; Raby, Benjamin; Arshad, Syed; German, Chris; Esko, Tõnu; Milani, Lili A.; Metspalu, Andres; Terao, Chikashi; Abuabara, Katrina; Løset, Mari; Hveem, Kristian; Jacobsson, Bo; Pino-Yanes, Maria; Strachan, David P.; Grarup, Niels; Linneberg, Allan; Lee, Young-Ae; Probst-Hensch, Nicole; Weidinger, Stephan; Jarvelin, Marjo-Riitta; Melén, Erik; Hakonarson, Hakon; Irvine, Alan D.; Jarvis, Deborah; Nijsten, Tamar; Duijts, Liesbeth; Vonk, Judith M.; Koppelmann, Gerard H.; Godfrey, Keith M.; Barton, Sheila J.; Feenstra, Bjarke; Pennell, Craig E.; Sly, Peter D.; Holt, Patrick G.; Williams, L. Keoki; Bisgaard, Hans; Bønnelykke, Klaus; Curtin, John; Simpson, Angela; Murray, Clare; Schikowski, Tamara; Bunyavanich, Supinda; Weiss, Scott T.; Holloway, John W.; Min, Josine L.; Brown, Sara J.; Standl, Marie; Paternoster, Lavinia (Journal article; Peer reviewed, 2023)Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery ... -
Latitude, Birth Date, and Allergy
Wjst, Matthias; Dharmage, Shyamali; André, Elisabeth; Norbäck, Dan; Raherison, Chantal; Villani, Simona; Manfreda, Jure; Sunyer, Jordi; Jarvis, Deborah; Burney, Peter; Svanes, Cecilie (PLoS Medicine 2(10): e294, Peer reviewed; Journal article, 2005-10-04)Background: The space and time distribution of risk factors for allergic diseases may provide insights into disease mechanisms. Allergy is believed to vary by month of birth, but multinational studies taking into account ... -
Menopause as a predictor of new-onset asthma
Triebner, Kai; Johannessen, Ane; Puggini, Luca; Benediktsdottir, Bryndis; Bertelsen, Randi Jacobsen; Bifulco, Ersilia; Dharmage, Shyamali C.; Franklin, Karl A.; Gislason, Þórarinn; Holm, Mathias; Jarvis, Deborah; Leynaert, Bénédicte; Lindberg, Eva; Macsali, Ferenc; Malinovschi, Andrej; Norbäck, Dan; Omenaas, Ernst; Rodriguez, Francisco J; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Wieslander, Gunilla; Zemp, Elisabeth; Svanes, Cecilie; Hustad, Simon Steinar; Gomez Real, Francisco (Peer reviewed; Journal article, 2015-01)Background: There is limited and conflicting evidence on the effect of menopause on asthma. Objectives: We sought to study whether the incidence of asthma and respiratory symptoms differ by menopausal status in a longitudinal ... -
Pharmacological treatment of asthma in a cohort of adults during a 20-year period: results from the European Community Respiratory Health Survey I, II and III
Janson, Christer; Accordini, Simone; Cazzoletti, Lucia; Cerveri, Isa; Chanoine, S; Corsico, Angelo; Ferreira, D.S.; Garcia-Aymerich, Judith; Gislason, Thorarinn; Nielsen, Rune; Johannessen, Ane; Jõgi, Rain; Malinovschi, Andrei; Moratalla, Jesús Martínez; Marcon, Alessandro; Pin, Isabelle; Quint, JK; Siroux, Valerie; Almar, Enrique; Bellisario, Valeria; Franklin, Karl A.; Gullon, JA; Holm, Mathias; Heinrich, Joachim; Nowak, Dennis; Sánchez-Ramos, José Luis; Weyler, Joost; Jarvis, Deborah (Peer reviewed; Journal article, 2019)Asthma often remains uncontrolled, despite the fact that the pharmacological treatment has undergone large changes. We studied changes in the treatment of asthma over a 20-year period and identified factors associated with ... -
Physical activity and lung function—Cause or consequence?
Bédard, Annabelle; Carsin, Anne-Elie; Fuertes, Elaine; Accordini, Simone; Dharmage, Shyamali C.; Garcia-Larsen, Vanessa; Heinrich, Joachim; Janson, Christer; Johannessen, Ane; Leynaert, Bénédicte; Sánchez-Ramos, José Luis; Peralta, Gabriela P.; Pin, Isabelle; Squillacioti, Giulia; Weyler, Joost; Jarvis, Deborah; Garcia-Aymerich, Judith (Journal article; Peer reviewed, 2020)Concerns exist that the positive association of physical activity with better lung function, which has been suggested in previous longitudinal studies in smokers, is due to reverse causation. To investigate this, we applied ... -
Predictors of microbial agents in dust and respiratory health in the Ecrhs
Tischer, Christina; Zock, Jan-Paul; Valkonen, Maria; Doekes, Gert; Guerra, Stefano; Heederick, Dick; Jarvis, Deborah; Norbäck, Dan; Olivieri, Mario; Sunyer, Jordi; Svanes, Cecilie; Täubel, Martin; Thiering, Elisabeth; Verlato, Guiseppe; Hyvärinen, Anne; Heinrich, Joachim (Peer reviewed; Journal article, 2015-05-02)Background Dampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to assess ... -
Prenatal and prepubertal exposures to tobacco smoke in men may cause lower lung function in future offspring: a three-generation study using a causal modelling approach
Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndis; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali C.; Forsberg, Bertil; Real, Francisco Gomez; Holloway, John W.; Holm, Mathias; Janson, Christer; Jõgi, Nils O.; Jõgi, Rain; Malinovschi, Andrei; Marcon, Alessandro; Martínez-Moratalla Rovira, Jesús; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Torén, Kjell; Jarvis, Deborah; Svanes, Cecilie (Journal article; Peer reviewed, 2021)Mechanistic research suggests that lifestyle and environmental factors impact respiratory health across generations by epigenetic changes transmitted through male germ cells. Evidence from studies on humans is very ... -
Residential greenspace and lung function decline over 20 years in a prospective cohort: The ECRHS study
Markevych, Iana; Zhao, Tianyu; Fuertes, Elaine; Marcon, Alessandro; Dadvand, Payam; Vienneau, Danielle; Garcia Aymerich, Judith; Nowak, Dennis; de Hoogh, Kees; Jarvis, Deborah; Abramson, Michael J.; Accordini, Simone; Amaral, Andre FS; Bentouhami, Hayat; Bertelsen, Randi Jacobsen; Boudier, Anne; Bono, Roberto; Bowatte, Gayan; Casas, Lidia; Dharmage, Shyamali C; Forsberg, Bertil; Gislason, Thorarinn; Gnesi, Marco; Holm, Mathias; Jacquemin, Benedicte; Janson, Christer; Jogi, Rain; Johannessen, Ane; Keidel, Dirk; Leynaert, Benedicte; Maldonado Perez, José Antonio; Marchetti, Pierpaolo; Migliore, Enrica; Martínez-Moratalla, Jesús; Orru, Hans; Pin, Isabelle; Potts, James; Probst-Hensch, Nicole; Ranzi, Andrea; Sánchez-Ramos, José Luis; Siroux, Valerie; Soussan, David; Sunyer, Jordi; Urrutia Landa, Isabel; Villani, Simona; Heinrich, Joachim (Journal article; Peer reviewed, 2023)Background: The few studies that have examined associations between greenspace and lung function in adulthood have yielded conflicting results and none have examined whether the rate of lung function decline is ... -
Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey
Flexeder, Claudia; Zock, Jan-Paul; Jarvis, Deborah; Verlato, Giuseppe; Olivieri, Mario; Benke, Geza; Abramson, Michael J.; Sigsgaard, Torben; Svanes, Cecilie; Torén, Kjell; Nowak, Dennis; Jõgi, Rain; Martínez-Moratalla, Jesús; Demoly, Pascal; Janson, Christer; Gíslason, Þórarinn; Bono, Roberto; Holm, Mathias; Franklin, Karl A.; Garcia-Aymerich, Judith; Siroux, Valérie; Leynaert, Bénédicte; Dorado Arenas, Sandra; Corsico, Angelo Guido; Pereira-Vega, Antonio; Probst-Hensch, Nicole; Urrutia Landa, Isabel; Schulz, Holger; Heinrich, Joachim (Peer reviewed; Journal article, 2019-02-14)Background: Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated ...