• Basic mechanisms for control of appetite and feed intake in Atlantic salmon (Salmo salar) 

      Kalananthan, Tharmini (Doctoral thesis, 2022-11-10)
      Atlantisk laks (Salmo salar L.) er en nøkkelart i norsk sjømateksport, og representerer 70 – 80 Mrd NOK i verdi. Den store økningen i produksjon kombinert med overfôring har bidratt til negative effekter på det marine ...
    • Brain Distribution of 10 cart Transcripts and Their Response to 4 Days of Fasting in Atlantic Salmon (Salmo salar L.) 

      Kalananthan, Tharmini; Gomes, Ana S.; Lai, Floriana; Tolås, Ingvill; Jordal, Ann-Elise O.; Norland, Sissel; Murashita, Koji; Rønnestad, Ivar (Journal article; Peer reviewed, 2021-10-25)
      Cocaine- and amphetamine-regulated transcript (CART) has been known to be involved in feeding and energy balance in mammals, acting as an anorexigenic neuropeptide in hypothalamus. In Atlantic salmon, little is known about ...
    • Disintegration stability of extruded fish feed affects gastric functions in Atlantic salmon (Salmo salar) 

      Bogevik, André Sture; Samuelsen, Tor Andreas; Aspevik, Tone; Romarheim, Odd Helge; Aas, Turid Synnøve; Kalananthan, Tharmini; Rønnestad, Ivar (Journal article; Peer reviewed, 2021)
      In the present study, two salmon feeds with different disintegration stabilities were produced by impacting extruder viscous heat dissipation with the use of different lipid levels in the feed mix. The feeds were then dried ...
    • Effects of short term fasting on mRNA expression of ghrelin and the peptide transporters PepT1 and 2 in Atlantic salmon (Salmo salar) 

      Del Vecchio, Gianmarco; Lai, Floriana; Gomes, Ana S.; Verri, Tiziano; Kalananthan, Tharmini; Barca, Amilcare; Handeland, Sigurd Olav; Rønnestad, Ivar (Journal article; Peer reviewed, 2021)
      Food intake is a vital process that supplies necessary energy and essential nutrients to the body. Information regarding luminal composition in the gastrointestinal tract (GIT) collected through mechanical and nutrient ...
    • Hypothalamic agrp and pomc mRNA Responses to Gastrointestinal Fullness and Fasting in Atlantic Salmon (Salmo salar, L.) 

      Kalananthan, Tharmini; Murashita, Koji; Rønnestad, Ivar; Ishigaki, Mitsumasa; Takahashi, Kota; Silva, Marta Sofia; Wakabayashi, Yuki; Lai, Floriana; Shimizu, Munetaka; Nilsen, Tom Ole; Martinez, Enrique Pino; Gomes, Ana S. (Journal article; Peer reviewed, 2020-02-11)
      The orexigenic agouti-related protein (AgRP) and the anorexigenic pro-opiomelanocortin (POMC) are crucial players in the control of feed intake in vertebrates, yet their role in teleosts has not been fully established. ...
    • Impact of long-term fasting on the stomach-hypothalamus appetite regulating genes in Atlantic salmon postsmolts 

      Kalananthan, Tharmini; Folkedal, Ole; Gomes, Ana S.; Lai, Floriana; Handeland, Sigurd Olav; Tolås, Ingvill; Gelebart, Virginie; Rønnestad, Ivar (Journal article; Peer reviewed, 2023)
      Atlantic salmon will experience periods of fasting during its lifecycle. In nature, prolonged fasting periods occur owing to seasonal fluctuations in available feeds, migration or in relation to reproduction. In a culture ...
    • Laboratory contamination in airway microbiome studies 

      Drengenes, Christine; Wiker, Harald G; Kalananthan, Tharmini; Nordeide, Eli; Eagan, Tomas Mikal; Nielsen, Rune (Peer reviewed; Journal article, 2019-08-14)
      Background The low bacterial load in samples acquired from the lungs, have made studies on the airway microbiome vulnerable to contamination from bacterial DNA introduced during sampling and laboratory processing. We have ...
    • The Melanocortin System in Atlantic Salmon (Salmo salar L.) and Its Role in Appetite Control 

      Kalananthan, Tharmini; Lai, Floriana; Gomes, Ana S.; Murashita, Koji; Handeland, Sigurd O; Rønnestad, Ivar (Journal article; Peer reviewed, 2020-08-21)
      The melanocortin system is a key neuroendocrine network involved in the control of food intake and energy homeostasis in vertebrates. Within the hypothalamus, the system comprises two main distinct neuronal cell populations ...
    • Protected sampling is preferable in bronchoscopic studies of the airway microbiome 

      Grønseth, Rune; Drengenes, Christine; Wiker, Harald G; Tangedal, Solveig; Xue, Yaxin; Husebø, Gunnar; Svanes, Øistein; Lehmann, Sverre; Aardal, Marit Elisabeth; Hoang, Tuyen; Kalananthan, Tharmini; Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Aanerud, Marianne; Nordeide, Eli; Haaland, Ingvild; Jonassen, Inge; Bakke, Per S.; Eagan, Tomas Mikal (Journal article; Peer reviewed, 2017)
      The aim was to evaluate susceptibility of oropharyngeal contamination with various bronchoscopic sampling techniques. 67 patients with obstructive lung disease and 58 control subjects underwent bronchoscopy with ...
    • Regional Expression of npy mRNA Paralogs in the Brain of Atlantic Salmon (Salmo salar, L.) and Response to Fasting 

      Tolås, Ingvill; Kalananthan, Tharmini; Gomes, Ana S.; Lai, Floriana; Norland, Sissel; Murashita, Koji; Rønnestad, Ivar (Journal article; Peer reviewed, 2021-08-26)
      Neuropeptide Y (NPY) is known as a potent orexigenic signal in vertebrates, but its role in Atlantic salmon has not yet been fully established. In this study, we identified three npy paralogs, named npya1, npya2, and npyb, ...