• Age, risk, and life expectancy in Norwegian intensive care: a registry-based population modelling study. 

      Lindemark, Frode; Haaland, Øystein Ariansen; Kvåle, Reidar; Flaatten, Hans; Johansson, Kjell Arne (Peer reviewed; Journal article, 2015-05-26)
      Background: Knowledge about the expected life years gained from intensive care unit (ICU) admission could inform priority-setting decisions across groups of ICU patients and across medical specialties. The aim of this study ...
    • A calibration study of SAPS II with Norwegian intensive care registry data 

      Haaland, Øystein Ariansen; Lindemark, Frode; Flaatten, Hans; Kvåle, Reidar; Johansson, Kjell Arne (Peer reviewed; Journal article, 2014-05-12)
      Background Mortality prediction is important in intensive care. The Simplified Acute Physiology Score (SAPS) II is a tool for predicting such mortality. However, the original SAPS II is poorly calibrated to current intensive ...
    • Characteristics, management and survival of ICU patients with coronavirus disease-19 in Norway, March-June 2020. A prospective observational study 

      Laake, Jon Henrik; Buanes, Eirik A.; Småstuen, Milada C.; Kvåle, Reidar; Olsen, Brita Fosser; Rustøen, Tone; Strand, Kristian; Sørensen, Vibecke; Hofsø, Kristin (Journal article; Peer reviewed, 2021)
      Background: Norwegian hospitals have operated within capacity during the COVID-19 pandemic. We present patient and management characteristics, and outcomes for the entire cohort of adult (>18 years) COVID-19 patients ...
    • Costs and expected gain in lifetime health from intensive care versus general ward care of 30,712 individual patients: A distribution-weighted cost-effectiveness analysis 

      Lindemark, Frode; Haaland, Øystein Ariansen; Kvåle, Reidar; Flaatten, Hans; Norheim, Ole Frithjof; Johansson, Kjell Arne (Peer reviewed; Journal article, 2017-08-21)
      Background: Clinicians, hospital managers, policy makers, and researchers are concerned about high costs, increased demand, and variation in priorities in the intensive care unit (ICU). The objectives of this modelling ...
    • COVID-19 and venous thromboembolism - prophylaxis and treatment 

      Kvåle, Reidar; Azrakhsh, , Nessar Ahmad; Mohn, Kristin Greve-Isdahl; Aanerud, Marianne; Guttormsen, Anne Berit; Reikvam, Håkon (Journal article; Peer reviewed, 2020)
    • External validation of SAPS II score reported to the Norwegian Intensive Care and Pandemic Registry (NIPaR) 

      Buanes, Eirik Alnes; Bruserud, Øyvind; Carracedo Huroz, Sergio; Barratt-Due, Andreas; Flaatten, Hans Kristian; Kvåle, Reidar (Journal article; Peer reviewed, 2023)
      Background: Simplified Acute Physiology Score II (SAPS II) is a mortality prediction model widely used to compensate for differences between intensive care units (ICU) in benchmarking and research. Accuracy of SAPS II is ...
    • A first-level customization study of SAPS II with Norwegian Intensive Care and Pandemic Registry (NIPaR) data 

      Bruserud, Øyvind; Haaland, Øystein Ariansen; Kvåle, Reidar; Buanes, Eirik Alnes (Journal article; Peer reviewed, 2023)
      Background: Severity scores and mortality prediction models (MPMs) are important tools for benchmarking and stratification in the intensive care unit (ICU) and need to be regularly updated using data from a local and ...
    • Increased risk of hospitalisation and intensive care admission associated with reported cases of SARS-CoV-2 variants B.1.1.7 and B.1.351 in Norway, December 2020-May 2021 

      Veneti, Lamprini; Seppälä, Elina Marjukka; Storm, Margrethe Larsdatter; Valcarcel Salamanca, Beatriz; Buanes, Eirik Alnes; Aasand, Nina Therese; Naseer, Mohammed Umaer; Bragstad, Karoline; Hungnes, Olav; Bøås, Håkon; Kvåle, Reidar; Samareh Golestani, Karan; Feruglio, Siri Laura; Vold, Line; Nygård, Karin Maria; Whittaker, Robert Neil (Journal article; Peer reviewed, 2021)
      Introduction Since their emergence, SARS-CoV-2 variants of concern (VOC) B.1.1.7 and B.1.351 have spread worldwide. We estimated the risk of hospitalisation and admission to an intensive care unit (ICU) for infections ...
    • Length of hospital stay and risk of intensive care admission and in-hospital death among COVID-19 patients in Norway: a register-based cohort study comparing patients fully vaccinated with an mRNA vaccine to unvaccinated patients 

      Whittaker, Robert Neil; Kristoffersen, Anja Bråthen; Valcarcel Salamanca, Beatriz; Seppälä, Elina Marjukka; Samareh Golestani, Karan; Kvåle, Reidar; Watle, Sara Sofie Viksmoen; Buanes, Eirik Alnes (Journal article; Peer reviewed, 2022)
      Objectives We estimated the length of stay (LoS) in hospital and the intensive care unit (ICU) and risk of admission to ICU and in-hospital death among COVID-19 patients ≥18 years in Norway who had been fully vaccinated ...
    • Long-term survival and quality of life after intensive care for patients 80 years of age or older 

      Andersen, Finn H; Flaatten, Hans; Klepstad, Pål; Romild, Ulla Kristina; Kvåle, Reidar (Peer reviewed; Journal article, 2015-06-03)
      Background: Comparison of survival and quality of life in a mixed ICU population of patients 80 years of age or older with a matched segment of the general population. Methods: We retrospectively analyzed survival of ICU ...
    • Multiple organ failure after trauma affects even long- term survival and functional status 

      Ulvik, Atle; Kvåle, Reidar; Wentzel-Larsen, Tore; Flaatten, Hans (Peer reviewed; Journal article, 2007-09-04)
      Background The aim of this study was to assess the incidence of organ failure in trauma patients treated in an intensive care unit (ICU), and to study the relationship between organ failure and long-term survival and ...
    • No difference in risk of hospitalization between reported cases of the SARS-CoV-2 Delta variant and Alpha variant in Norway 

      Veneti, Lamprini; Valcarcel Salamanca, Beatriz; Seppälä, Elina Marjukka; Starrfelt, Jostein; Storm, Margrethe Larsdatter; Bragstad, Karoline; Hungnes, Olav; Bøås, Håkon; Kvåle, Reidar; Vold, Line; Nygård, Karin Maria; Buanes, Eirik Alnes; Whittaker, Robert Neil (Journal article; Peer reviewed, 2022)
      Objectives To estimate the risk of hospitalization among reported cases of the Delta variant of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) compared with the Alpha variant in Norway, and the risk of ...
    • Reduced risk of hospitalisation among reported COVID-19 cases infected with the SARS-CoV-2 Omicron BA.1 variant compared with the Delta variant, Norway, December 2021 to January 2022 

      Veneti, Lamprini; Bøås, Håkon; Kristoffersen, Anja Bråthen; Stålcrantz, Jeanette; Bragstad, Karoline; Hungnes, Olav; Storm, Margrethe Larsdatter; Aasand, Nina Therese; Rø, Gunnar Øyvind Isaksson; Starrfelt, Jostein; Seppälä, Elina Marjukka; Kvåle, Reidar; Vold, Line; Nygård, Karin; Buanes, Eirik Alnes; Whittaker, Robert Neil (Journal article; Peer reviewed, 2022)
      We included 39,524 COVID-19 Omicron and 51,481 Delta cases reported in Norway from December 2021 to January 2022. We estimated a 73% reduced risk of hospitalisation (adjusted hazard ratio: 0.27; 95% confidence interval: ...
    • Thrombocytopaenia in the critically ill 

      Bruserud, Øyvind; Mosevoll, Knut Anders; Kristoffersen, Einar Klæboe; Kvåle, Reidar; Reikvam, Håkon (Journal article; Peer reviewed, 2021)
    • Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU) 

      Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Van De Louw, Andry; Barratt-Due, Andreas; Chawla, Sanjay; Castro, Pedro; Póvoa, Pedro; Coelho, Luis; Metaxa, Victoria; Kochanek, Matthias; Liebregts, Tobias; Kander, Thomas; Hästbacka, Johanna; Andreasen, Jo Bønding; Péju, Edwige; Nielsen, Lene Bjerregaard; Hvas, Christine Lodberg; Dufranc, Etienne; Canet, Emmanuel; Lundqvist, Linda; Wright, Christopher John; Schmidt, Julien; Uhel, Fabrice; Ait-Oufella, Hafid; Krag, Mette; Cos Badia, Elisabet; Díaz-Lagares, Cándido; Menat, Sophie; Voiriot, Guillaume; Clausen, Niels Erikstrup; Lorentzen, Kristian; Kvåle, Reidar; Hildebrandt, Thomas; Holten, Aleksander Rygh; Strand, Kristian; Tzalavras, Asterios; Bestle, Morten Heiberg; Klepstad, Pål; Fernandez, Sara; Vimpere, Damien; Paulino, Carolina; Graça, Carina; Lueck, Catherina; Juhl, Christian Svendsen; Costa, Carolina; Bådstøløkken, Per Martin; Miranda, Teresa; Lêdo, Lia Susana Aires; Sousa Torres, Joao Carlos; Granholm, Anders; Møller, Morten Hylander; Russell, Lene; Khalil, Ahmed; Yehia, Ahmed; Salem, Haney; Farahat, Hesham; Sudevan, Manu; Biggart, Melissa; Fatima, Nirmeen; Elkhonezy, Mohammed; Bunzel, Anne-Marie; Siegumfeldt, Rine M.; Vestergaard, Stine R.; Pelle, Juliette; Lê, Minh-Pierre; Vigneron, Clara; Bertrix, Morgane; Cirera, Paul; Laghlam, Driss; Bredin, Swann; Marin, Nathalie; Toppenberg, Maria; Benelli, Brice; Seguin, Amélie; Garret, Charlotte; Guillotin, Florian; Blonz, Gauthier; Lascarrou, Jean-Baptiste; Lemarie, Jérémie; Desmedt, Luc; Agbakou, Maïté; Carpentier, Mathieu; Martin, Maëlle; Benkalfate, Naïla; Zambon, Olivier; Decamps, Paul; Wilquin, Pauline L.; Benguerfi, Soraya; Gardner, John; Remor, Natalie; Carr, Sheila; Yang, Gloria; Gernez, Coralie; Thiry, Ingrid; Missri, Louai; Denneborg, Moritz K. G.; Brown, Katherine; Casares, Vanessa; Sivula, Mirka; Lappi, Elina; Pettilä, Leena; Heinonen, Jonna; Saario, Minttu; Mecheri, Manal K.; Elabbadi, Alezandre; Desnos, Cyrielle; Lafarge, Antoine; Mghirbi, Olfa; Sjøbø, Brit Ågot; Christoffersen, Cecilie; Bestle, Frederik H.; Lemos, Claudia; Gonçalves, Cristiana V.; Jacinto, Nuno M. B.; Anselmo, Monica P.; Hoeper, Marius M.; Hoff, Marja; Simões Freire, Pedro M. (Journal article; Peer reviewed, 2023)
      Purpose Thrombocytopenia (platelet count < 150 × 109/L) is common in intensive care unit (ICU) patients and is likely associated with worse outcomes. In this study we present international contemporary data on ...
    • Validation of a point-of-care capillary lactate measuring device (Lactate Pro 2) 

      Raa, Anette; Sunde, Geir Arne; Bolann, Bjørn Johan; Kvåle, Reidar; Bjerkvig, Christopher Kalhagen; Eliassen, Håkon Skogrand; Wentzel-Larsen, Tore; Heltne, Jon-Kenneth (Journal article; Peer reviewed, 2020)
      Background The measurement of lactate in emergency medical services has the potential for earlier detection of shock and can be performed with a point-of-care handheld device. Validation of a point-of-care handheld device ...