Blar i Bergen Open Research Archive på forfatter "Leiten, Elise Orvedal"

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    • The airway microbiota of stable COPD : Association with exacerbation frequency and the risks associated with bronchoscopic data collection 

      Leiten, Elise Orvedal (Doctoral thesis, 2022-03-25)
      Background: Acute exacerbations of COPD are an important cause of mortality and morbidity in patients with COPD. It is incompletely understood why some COPD patients experience frequent exacerbations, while others rarely ...

    • Complications and discomfort after research bronchoscopy in the MicroCOPD study 

      Leiten, Elise Orvedal; Eagan, Tomas Mikal; Martinsen, Einar Marius Hjellestad; Nordeide, Eli; Husebø, Gunnar; Knudsen, Kristel Svalland; Lehmann, Sverre; Svanes, Øistein; Bakke, Per S.; Nielsen, Rune (Journal article; Peer reviewed, 2020)
      Background: Data on discomfort and complications from research bronchoscopy in chronic obstructive pulmonary disease (COPD) and asthma is limited. We present complications and discomfort occurring within a week after ...

    • Complications and discomfort of bronchoscopy: a systematic review 

      Leiten, Elise Orvedal; Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal; Bakke, Per S.; Grønseth, Rune (Peer reviewed; Journal article, 2016)
      Objective: To identify bronchoscopy-related complications and discomfort, meaningful complication rates, and predictors. Method: We conducted a systematic literature search in PubMed on 8 February 2016, using a search ...

    • A longitudinal study of the pulmonary mycobiome in subjects with and without chronic obstructive pulmonary disease 

      Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal Lind; Wiker, Harald Gotten; Leiten, Elise Orvedal; Husebø, Gunnar Reksten; Knudsen, Kristel Svalland; Tangedal, Solveig; Sanseverino, Walter; Paytuví-Gallart, Andreu; Nielsen, Rune (Journal article; Peer reviewed, 2022-05-12)
      Background: Few studies have examined the stability of the pulmonary mycobiome. We report longitudinal changes in the oral and pulmonary mycobiome of participants with and without COPD in a large-scale bronchoscopy study ...

    • Motivation and response rates in bronchoscopy studies 

      Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal; Leiten, Elise Orvedal; Nordeide, Eli; Bakke, Per S.; Lehmann, Sverre; Nielsen, Rune (Peer reviewed; Journal article, 2019-05-02)
      Background Bronchoscopy is frequently used to sample the lower airways in lung microbiome studies. Despite being a safe procedure, it is associated with discomfort that may result in reservations regarding participation ...

    • Participation in research bronchoscopy: a literature review 

      Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Bakke, Per S.; Eagan, Tomas Mikal; Grønseth, Rune (Peer reviewed; Journal article, 2016-02-03)
      Bronchoscopy is the preferred method for collecting biological samples from the lower airways of subjects in clinical research. However, ensuring participation in clinical research can be challenging when the research ...

    • Protected sampling is preferable in bronchoscopic studies of the airway microbiome 

      Grønseth, Rune; Drengenes, Christine; Wiker, Harald G; Tangedal, Solveig; Xue, Yaxin; Husebø, Gunnar; Svanes, Øistein; Lehmann, Sverre; Aardal, Marit Elisabeth; Hoang, Tuyen; Kalananthan, Tharmini; Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Aanerud, Marianne; Nordeide, Eli; Haaland, Ingvild; Jonassen, Inge; Bakke, Per S.; Eagan, Tomas Mikal (Journal article; Peer reviewed, 2017)
      The aim was to evaluate susceptibility of oropharyngeal contamination with various bronchoscopic sampling techniques. 67 patients with obstructive lung disease and 58 control subjects underwent bronchoscopy with ...

    • The pulmonary mycobiome—A study of subjects with and without chronic obstructive pulmonary disease 

      Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal Lind; Leiten, Elise Orvedal; Haaland, Ingvild; Husebø, Gunnar Reksten; Knudsen, Kristel Svalland; Drengenes, Christine; Sanseverino, Walter; Paytuví-Gallart, Andreu; Nielsen, Rune (Journal article; Peer reviewed, 2021-04-07)
      Background: The fungal part of the pulmonary microbiome (mycobiome) is understudied. We report the composition of the oral and pulmonary mycobiome in participants with COPD compared to controls in a large-scale single-centre ...