Blar i Bergen Open Research Archive på forfatter "Leversen, Nils Anders"
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Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway
De Souza, Gustavo Antonio; Leversen, Nils Anders; Målen, Hiwa; Wiker, Harald G (Peer reviewed; Journal article, 2011-12-21)Correct protein compartmentalization is a key step for molecular function and cell viability, and this is especially true for membrane and externalized proteins of bacteria. Recent proteomic reports of Bacillus subtilis ... -
Counting Mycobacteria in Infected Human Cells and Mouse Tissue: A Comparison between qPCR and CFU
Pathak, Sharad; Awuh, Jane A.; Leversen, Nils Anders; Flo, Trude H.; Åsjø, Birgitta (Peer reviewed; Journal article, 2012-04-19)Due to the slow growth rate and pathogenicity of mycobacteria, enumeration by traditional reference methods like colony counting is notoriously time-consuming, inconvenient and biohazardous. Thus, novel methods that rapidly ... -
Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosis infected lungs and lymph node tissues
Mustafa, Tehmina; Leversen, Nils Anders; Sviland, Lisbet; Wiker, Harald G. (Peer reviewed; Journal article, 2014-10-03)Background: The clinical course of tuberculosis (TB) infection, bacterial load and the morphology of lesions vary between pulmonary and extrapulmonary TB. Antigens expressed in abundance during infection could represent ... -
Secreted proteins of mycobacteria and their role during infection
Leversen, Nils Anders (Doctoral thesis, 2012-03-23)One-third of the world’s population is infected with the causative agent of tuberculosis, Mycobacterium tuberculosis. A fraction of infected individuals have an active form of the disease, while the remainder is able to ...