Browsing Bergen Open Research Archive by Author "Noel, Agnes"
Now showing items 1-2 of 2
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Cancer-associated fibroblasts in desmoplastic tumors: emerging role of integrins
Zeltz, Cedric; Primac, Irina; Murugan Erusappan, Pugazendhi; Alam, Jahedul; Noel, Agnes; Gullberg, Donald (Peer reviewed; Journal article, 2019)The tumor microenvironment (TME) is a complex meshwork of extracellular matrix (ECM) macromolecules filled with a collection of cells including cancer-associated fibroblasts (CAFs), blood vessel associated smooth muscle ... -
Stromal integrin α11 regulates PDGFR-β signaling and promotes breast cancer progression
PRIMAC, I; MAQUOI, E; BLACHER, S; HELJASVAARA, R; Van Deun, Jan; Smeland, Hilde Ytre-Hauge; CANALE, A; LOUIS, T; Stuhr, Linda Elin Birkhaug; SOUNNI, NE; CATALDO, D; PIHLAJANEMI, T; PEQUEUX, C; DE WEAVER, O; Gullberg, Donald; Noel, Agnes (Peer reviewed; Journal article, 2019)Cancer-associated fibroblasts (CAFs) are key actors in modulating the progression of many solid tumors, such as breast cancer (BC). Herein, we identify an integrin α11/PDGFRβ–positive CAF subset displaying tumor-promoting ...