Blar i Bergen Open Research Archive på forfatter "Omland, Torbjørn"
-
Adding stress biomarkers to high-sensitivity cardiac troponin for rapid non-ST-elevation myocardial infarction rule-out protocols
Restan, Ingar Ziad; Sanchez, Ana Yufera; Steiro, Ole-Thomas; Lopez-Ayala, Pedro; Tjora, Hilde Lunde; Langørgen, Jørund; Omland, Torbjørn; Boeddinghaus, Jasper; Nestelberger, Thomas; Koechlin, Luca; Collinson, Paul; Bjørneklett, Rune Oskar; Vikenes, Kjell; Strand, Heidi; Skadberg, Øyvind; Mjelva, Øistein; Larsen, Alf Inge; Vernon, Bonarjee; Mueller, Christian; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2022)Aims This study tested the hypothesis that combining stress-induced biomarkers (copeptin or glucose) with high-sensitivity cardiac troponin (hs-cTn) increases diagnostic accuracy for non-ST-elevation myocardial infarction ... -
Aiming toWards Evidence baSed inTerpretation of Cardiac biOmarkers in patients pResenting with chest pain using Point of Care Testing (WESTCOR-POC): study design
Thulin, Ingrid Viola Lavesson; Jordalen, Silje Marie Farestveit; Lekven, Ole Christian; Krishnapillai, Jeyaseelan; Steiro, Ole-Thomas; Collinson, Paul; Apple, Fred; Cullen, Louise; Norekvål, Tone Merete; Wisløff, Torbjørn; Vikenes, Kjell; Omland, Torbjørn; Bjørneklett, Rune Oskar; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2023)Objectives: Patients presenting with symptoms suggestive of acute coronary syndrome (ACS) contribute to a high workload and overcrowding in the Emergency Department (ED). Accelerated diagnostic protocols for non-ST-elevation ... -
Analytical considerations in deriving 99th percentile upper reference limits for high-sensitivity cardiac troponin assays: Educational recommendations from the IFCC committee on clinical application of cardiac bio-markers
Aakre, Kristin Moberg; Saenger, Amy K.; Body, Rick; Collinson, Paul; Hammarsten, Ola; Jaffe, Allan S.; Kavsak, Pete; Omland, Torbjørn; Ordonez-Lianos, Jordi; Apple, Fred S. (Journal article; Peer reviewed, 2022)The International Federation of Clinical Chemistry Committee on Clinical Application of Cardiac Bio-Markers provides evidence-based educational documents to facilitate uniform interpretation and utilization of cardiac ... -
Antibody-mediated interferences affecting cardiac troponin assays: recommendations from the IFCC Committee on Clinical Applications of Cardiac Biomarkers
Hammarsten, Ola; Warner, Janet V.; Lam, Leo; Kavsak, Peter; Lindahl, Bertil; Aakre, Kristin Moberg; Collinson, Paul; Jaffe, Allan S.; Saenger, Amy K.; Body, Richard; Mills, Nicholas L.; Omland, Torbjørn; Ordonez-Llanos, Jordi; Apple, Fred S. (Journal article; Peer reviewed, 2023)The International Federation of Clinical Chemistry Committee on Clinical Applications of Cardiac Biomarkers (IFCC C-CB) provides educational documents to facilitate the interpretation and use of cardiac biomarkers in ... -
Biological variation of cardiac myosin-binding protein C in healthy individuals
Alaour, Bashir; Omland, Torbjørn; Torsvik, Janniche; Kaier, Thomas E.; Sylte, Marit S.; Strand, Heidi; Quraishi, Jasmine; McGrath, Sam; Williams, Luke; Meex, Steven; Redwood, Simon; Marber, Michael; Aakre, Kristin M. (Journal article; Peer reviewed, 2021)Objectives Cardiac myosin-binding protein C (cMyC) is a novel biomarker of myocardial injury, with a promising role in the triage and risk stratification of patients presenting with acute cardiac disease. In this study, ... -
Biological variation of secretoneurin; a novel cardiovascular biomarker implicated in arrhythmogenesis
Aakre, Kristin Moberg; Ottesen, Anett Hellebø; Strand, Heidi; Faaren, Arne L.; Alaour, Bashir; Torsvik, Janniche; Sylte, Marit Sverresdotter; Marber, Michael; Christensen, Geir; Røsjø, Helge Rørvik; Omland, Torbjørn (Journal article, 2021)Background Secretoneurin is a novel prognostic biomarker that may predict mortality in heart failure and the occurrence of ventricular arrhythmias. This study reports the within subject variation (CVI), between subject ... -
Cardiac Troponin Assays With Improved Analytical Quality: A Trade-Off Between Enhanced Diagnostic Performance and Reduced Long-Term Prognostic Value
Tjora, Hilde Lunde; Steiro, Ole-Thomas; Langørgen, Jørund; Bjørneklett, Rune; Nygård, Ottar; Skadberg, Øyvind; Bonarjee, Vernon; Collinson, Paul; Omland, Torbjørn; Vikenes, Kjell; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2020)Background Cardiac troponin (cTn) permits early rule‐out/rule‐in of patients admitted with possible non–ST‐segment–elevation myocardial infarction. In this study, we developed an admission and a 0/1 hour rule‐out/rule‐in ... -
Cardiac troponin measurement at the point of care: educational recommendations on analytical and clinical aspects by the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (IFCC C-CB)
Collinson, Paul; Aakre, Kristin Moberg; Saenger, Amy; Body, Rick; Hammarsten, Ole; Jaffe, Allan S.; Kavsak, Pete; Omland, Torbjørn; Ordonez-Lianos, Jordi; Karon, Brad; Apple, Fred S. (Journal article; Peer reviewed, 2023)The International Federation of Clinical Chemistry and Laboarator Medicine (IFCC) Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has provided evidence-based educational resources to aid and improve the ... -
Diagnostic Performance of Novel Troponin Algorithms for the Rule-Out of Non-ST-Elevation Acute Coronary Syndrome
Tjora, Hilde Lunde; Steiro, Ole-Thomas; Langørgen, Jørund; Bjørneklett, Rune Oskar; Skadberg, Øyvind; Bonarjee, Vernon V S; Mjelva, Øistein; Collinson, Paul; Omland, Torbjørn; Vikenes, Kjell; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2022)Background The European Society of Cardiology (ESC) rule-out algorithms use cutoffs optimized for exclusion of non-ST elevation myocardial infarction (NSTEMI). We investigated these and several novel algorithms for the ... -
Endurance exercise training volume is not associated with progression of coronary artery calcification
Kleiven, Øyunn; Bjørkavoll-Bergseth, Magnus; Omland, Torbjørn; Aakre, Kristin Moberg; Frøysa, Vidar; Erevik, Christine B.; Greve, Ole Jacob; Melberg, Tor Harald; Auestad, Bjørn Henrik; Skadberg, Øyvind; Edvardsen, Thor; Ørn, Stein (Journal article; Peer reviewed, 2020)Background Recent cross‐sectional studies have suggested a dose‐dependent relationship between lifelong exposure to physical activity and the burden of calcified coronary artery disease (CAD). No longitudinal studies have ... -
Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction
Koppen, Elias; Omland, Torbjørn; Larsen, Alf Inge; Karlsen, Trine; Linke, Axel; Prescott, Eva Irene Bossano; Halle, Martin; Dalen, Håvard; Delagardelle, Charles; Hole, Torstein; van Craenenbroeck, Emeline M.; Beckers, Paul; Ellingsen, Øyvind; Feiereisen, Patrick; Valborgland, Torstein; Videm, Vibeke (Journal article; Peer reviewed, 2021)Aims Whether an exercise training intervention is associated with reduction in long-term high-sensitivity cardiac troponin T (hs-cTnT) concentration (a biomarker of subclinical myocardial injury) in patients with heart ... -
Exercise training and high-sensitivity cardiac troponin-I in patients with heart failure with reduced ejection fraction
Riveland, Egil Aarstad; Valborgland, Torstein; Ushakova, Anastasia; Skadberg, Øyvind; Karlsen, Trine; Hole, Torstein Laurits; Støylen, Asbjørn; Dalen, Håvard; Videm, Vibeke; Koppen, Elias; Linke, Axel; Delagardelle, Charles; Van Craenenbroeck, Emeline M.; Beckers, Paul; Prescott, Eva; Halle, Martin; Omland, Torbjørn; Ellingsen, Øyvind; Larsen, Alf Inge (Journal article; Peer reviewed, 2024)Aims The aims of this sub-study of the SMARTEX trial were (1) to evaluate the effects of a 12-week exercise training programme on serum levels of high sensitivity cardiac troponin I (hs-cTnI) in patients with moderate ... -
Growth Differentiation Factor 15: A Prognostic Marker in Patients with Acute Chest Pain without Acute Myocardial Infarction
Myrmel, Gard Mikael Saele; Steiro, Ole-Thomas; Tjora, Hilde Lunde; Langørgen, Jørund; Bjørneklett, Rune Oskar; Skadberg, Øyvind; Bonarjee, Vernon V S; Mjelva, Øistein; Pedersen, Eva Ringdal; Vikenes, Kjell; Omland, Torbjørn; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2023)Background Acute chest pain is associated with an increased risk of death and cardiovascular events even when acute myocardial infarction (AMI) has been excluded. Growth differentiation factor-15 (GDF-15) is a strong ... -
High-Sensitivity Cardiac Troponin I and T Response Following Strenuous Activity is Attenuated by Smokeless Tobacco: NEEDED (North Sea Race Endurance Exercise Study) 2014
Skranes, Julia Brox; Kleiven, Øyunn; Aakre, Kristin Moberg; Skadberg, Øyvind; Melberg, Tor Harald; Omland, Torbjørn; Ørn, Stein (Journal article; Peer reviewed, 2020)Background Use of snus, a smokeless tobacco product, is increasing in Scandinavia. Strenuous physical activity is associated with an acute increase in high‐sensitivity cardiac troponin (swhs‐cTn) concentrations. Current ... -
Implementing screening for myocardial injury in non-cardiac surgery: perspectives of an ad-hoc interdisciplinary expert group
Atar, Dan; Rosseland, Leiv Arne; Jammer, Ib; Aakre, Kristin Moberg; Wiseth, Rune; Molund, Marius; Gualandro, Danielle M; Omland, Torbjørn (Journal article; Peer reviewed, 2023)Objectives. Perioperative myocardial injury (PMI) is increasingly recognised as an important complication of non-cardiac surgery, with often clinically silent presentation, but detrimental prognosis. Active screening for ... -
The liver-heart axis in patients with severe obesity: the association between liver fibrosis and chronic myocardial injury may be explained by shared risk factors of cardiovascular disease
Young, Juliet; Seeberg, Kathrine; Aakre, Kristin Moberg; Borgeraas, Heidi; Nordstrand, Njord; Wisløff, Torbjørn; Hjelmesæth, Jøran Sture; Omland, Torbjørn; Hertel, Jens Kristoffer (Journal article; Peer reviewed, 2024)Background: Severe obesity is associated with increased risk of non-alcoholic fatty liver disease and cardiovascular disease. We hypothesized that liver fibrosis as quantified by the Enhanced Liver Fibrosis (ELF) test would ... -
N-terminal pro-B-type natriuretic peptide as a prognostic indicator for 30-day mortality following out-of-hospital cardiac arrest: A prospective observational study
Aarsetøy, Reidun; Omland, Torbjørn; Røsjø, Helge; Strand, Heidi; Lindner, Thomas Werner; Aarsetøy, Hildegunn; Staines, Harry; Nilsen, Dennis W.T. (Journal article; Peer reviewed, 2020-08-24)Background Early risk stratification applying cardiac biomarkers may prove useful in sudden cardiac arrest patients. We investigated the prognostic utility of early-on levels of high sensitivity cardiac troponin-T (hs-cTnT), ... -
N-terminal pro-B-type natriuretic peptide for prediction of ventricular arrhythmias: Data from the SMASH study
Sourour, Nur; Riveland, Egil Aarstad; Næsgaard, Patrycja; Kjekshus, Harald; Larsen, Alf Inge; Omland, Torbjørn; Røsjø, Helge Rørvik; Myhre, Peder Langeland (Journal article; Peer reviewed, 2023)Background Elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations predict heart failure (HF) and mortality, but whether NT-proBNP predicts ventricular arrhythmias (VA) is not clear. Hypothesis We ... -
Novel oxygen desaturation parameters are associated with cardiac troponin I: Data from the Akershus Sleep Apnea Project
Sigurdardóttir, Fjóla Dögg; Øverby, Tonje Caroline; Nikkonen, Sami; Karhu, Tuomas; Dammen, Toril; Nordhus, Inger Hilde; Thorshov, Thea Christine; Einvik, Gunnar; Kainulainen, Samu; Leppänen, Timo; Arnardottir, Erna Sif; Töyräs, Juha; Omland, Torbjørn; Hrubos-Strøm, Harald (Journal article; Peer reviewed, 2022)Novel diagnostic markers for obstructive sleep apnea beyond the apnea–hypopnea index (AHI) have been introduced. There are no studies on their association with markers of subclinical myocardial injury. We assessed the ... -
Obstructive sleep apnea, verbal memory, and executive function in a community-based high-risk population identified by the Berlin Questionnaire Akershus Sleep Apnea Project
Hrubos-Strøm, Harald; Nordhus, Inger Hilde; Einvik, Gunnar; Randby, Anna; Omland, Torbjørn; Sundet, Kjetil; Moum, Torbjørn; Dammen, Toril (Peer reviewed; Journal article, 2012)Purpose: Cognitive functions in community-dwelling adults at high risk of obstructive sleep apnea have not been described and nor are associations between cognitive functions and obstructive sleep apnea severity fully ...