Blar i Bergen Open Research Archive på forfatter "Ousdal, Olga Therese"
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The association of PTSD symptom severity with amygdala nuclei volumes in traumatized youths
Ousdal, Olga Therese; Milde, Anne Marita; Hafstad, Gertrud Sofie; Hodneland, Erlend; Dyb, Grete; Craven, Alexander R.; Melinder, Annika Maria D; Endestad, Tor; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)The amygdala is a core component in neurobiological models of stress and stress-related pathologies, including post-traumatic stress disorder (PTSD). While numerous studies have reported increased amygdala activity following ... -
Brain changes induced by electroconvulsive therapy are broadly distributed
Ousdal, Olga Therese; Argyelan, Miklos; Narr, Katherine L.; Abbott, Christopher; Wade, Benjamin; Vandenbulcke, Mathieu; Urretavizcaya, Mikel; Tendolkar, Indira; Takamiya, Akihiro; Stek, Max L.; Soriano-Mas, Carles; Redlich, Ronny; Paulson, Olaf B.; Oudega, Mardien L.; Opel, Nils; Nordanskog, Pia; Kishimoto, Taishiro; Kämpe, Robin; Jørgensen, Anders; Hanson, Lars G.; Hamilton, J. Paul; Espinoza, Randall; Emsell, Louise; van Eijndhoven, Philip; Dols, Annemieke; Dannlowski, Udo; Cardoner, Narcis; Bouckaert, Filip; Anand, Amit; Bartsch, Hauke; Kessler, Ute; Ødegaard, Ketil Joachim; Dale, Anders; Oltedal, Leif (Peer reviewed; Journal article, 2020-03-01)Background Electroconvulsive therapy (ECT) is associated with volumetric enlargements of corticolimbic brain regions. However, the pattern of whole-brain structural alterations following ECT remains unresolved. Here, we ... -
Characterization of gray matter volume changes from one week to 6 months after termination of electroconvulsive therapy in depressed patients
Laroy, Maarten; Bouckaert, Filip; Ousdal, Olga Therese; Dols, Annemieke; Rhebergen, Didi; van Exel, Eric; van Wingen, Guido; van Waarde, Jeroen; Verdijk, Joey; Kessler, Ute; Bartsch, Hauke; Jorgensen, Martin Balslev; Paulson, Olaf B.; Nordanskog, Pia; Prudic, Joan; Sienaert, Pascal; Vandenbulcke, Mathieu; Oltedal, Leif; Emsell, Louise (Journal article; Peer reviewed, 2024)Background Increased gray matter volume (GMV) following electroconvulsive therapy (ECT) has been well-documented, with limited studies reporting a subsequent decrease in GMV afterwards. Objective This study characterized ... -
Diffusion Tensor Imaging Before and 3 Months After Concentrated Exposure Response Prevention in Obsessive-Compulsive Disorder
Brecke, Vilde; Thorsen, Anders Lillevik; Ousdal, Olga Therese; Vriend, Chris; Alnæs, Dag; Hagen, Kristen; Hansen, Bjarne; Kvale, Gerd; van den Heuvel, Odile A (Journal article; Peer reviewed, 2021)Background: Subtle differences in white matter microstructure have been found in obsessive-compulsive disorder (OCD) compared to controls using diffusion tensor imaging (DTI), but it is unclear if and how this change after ... -
Disentangling Within- and Between-Person Effects During Response Inhibition in Obsessive-Compulsive Disorder
Hagland, Pernille; Thorsen, Anders Lillevik; Ousdal, Olga Therese; Gjestad, Rolf; de Wit, Stella J.; Hansen, Bjarne Kristian Aaslie; Hagen, Kristen; Kvale, Gerd; van den Heuvel, Odile A. (Journal article; Peer reviewed, 2021)Background: Obsessive-compulsive disorder (OCD) has been related to worse performance, abnormal brain activity, and functional connectivity during response inhibition. Whether these findings are indications of stable traits ... -
Effects of Bergen 4-Day Treatment on Resting-State Graph Features in Obsessive-Compulsive Disorder
Thorsen, Anders Lillevik; Vriend, Chris; de Wit, Stella J.; Ousdal, Olga Therese; Hagen, Kristen; Hansen, Bjarne; Kvale, Gerd; van den Heuvel, Odile A (Journal article; Peer reviewed, 2020)Background Exposure and response prevention is an effective treatment for obsessive-compulsive disorder (OCD), but it is unclear how symptom reduction is related to changes in the brain. We aimed to determine the effects ... -
Electroconvulsive therapy and cognitive performance from the Global ECT MRI Research Collaboration
Kiebs, Maximilian; Farrar, Danielle C.; Yrondi, Antoine; Cardoner, Narcis; Tuovinen, Noora; Redlich, Ronny; Dannlowski, Udo; Soriano-Mas, Carles; Dols, Annemiek; Takamiya, Akihiro; Tendolkar, Indira; Narr, Katherine L.; Espinoza, Randall; Laroy, Maarten; van Eijndhoven, Philip; Verwijk, Esmée; van Waarde, Jeroen; Verdijk, Joey; Maier, Hannah B.; Nordanskog, Pia; van Wingen, Guido; van Diermen, Linda; Emsell, Louise; Bouckaert, Filip; Repple, Jonathan; Camprodon, Joan A.; Wade, Benjamin S.C.; Donaldson, K. Tristan; Oltedal, Leif; Kessler, Ute; Hammar, Åsa Karin; Sienaert, Pascal; Hebbrecht, Kaat; Urretavizcaya, Mikel; Belge, Jean-Baptiste; Argyelan, Miklos; Baradits, Mate; Obbels, Jasmien; Draganski, Bogdan; Philipsen, Alexandra; Sartorius, Alexander; Rhebergen, Didericke; Ousdal, Olga Therese; Hurlemann, René; McClintock, Shawn; Erhardt, Erik B.; Abbott, Christopher C. (Journal article; Peer reviewed, 2024)The Global ECT MRI Research Collaboration (GEMRIC) has collected clinical and neuroimaging data of patients treated with electroconvulsive therapy (ECT) from around the world. Results to date have focused on neuroimaging ... -
Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Argyelan, Miklos; Deng, Zhi-De; Ousdal, Olga Therese; Oltedal, Leif; Angulo, Brian; Baradits, Mate; Spitzberg, Andrew J.; Kessler, Ute; Sartorius, Alexander; Dols, Annemiek; Narr, Katherine L.; Espinoza, Randall; van Waarde, Jeroen A.; Tendolkar, Indira; van Eijndhoven, Philip; van Wingen, Guido A.; Takamiya, Akihiro; Kishimoto, Taishiro; Jorgensen, Martin B.; Jorgensen, Anders; Paulson, Olaf B.; Yrondi, Antoine; Péran, Patrice; Soriano-Mas, Carles; Cardoner, Narcis; Cano, Marta; van Diermen, Linda; Schrijvers, Didier; Belge, Jean-Baptiste; Emsell, Louise; Bouckaert, Filip; Vandenbulcke, Mathieu; Kiebs, Maximilian; Hurlemann, René; Mulders, Peter Cr.; Redlich, Ronny; Dannlowski, Udo; Erhan, Kavakbasi; Kritzer, Michael D.; Ellard, Kristen K.; Camprodon, Joan A.; Petrides, Georgios; Malhotra, Anil K.; Abbott, Christopher C. (Journal article; Peer reviewed, 2023)Neurostimulation is a mainstream treatment option for major depression. Neuromodulation techniques apply repetitive magnetic or electrical stimulation to some neural target but significantly differ in their invasiveness, ... -
Elevated body weight modulates subcortical volume change and associated clinical response following electroconvulsive therapy
Opel, Nils; Narr, Katherine L; Abbott, Christopher; Argyelan, Miklos; Espinoza, Randall; Emsell, Louise; Bouckaert, Filip; Sienaert, Pascal; Vandenbulcke, Mathieu; Nordanskog, Pia; Repple, Jonathan; Kavakbasi, Erhan; Jorgensen, Martin B.; Paulson, Olaf B.; Hanson, Lars G.; Dols, Annemieke; van Exel, Eric; Oudega, Mardien L.; Takamiya, Akihiro; Kishimoto, Taishiro; Ousdal, Olga Therese; Haavik, Jan; Hammar, Åsa Karin; Ødegaard, Ketil Joachim; Kessler, Ute; Bartsch, Hauke; Dale, Anders M.; Baune, Bernhard T; Dannlowski, Udo; Oltedal, Leif; Redlich, Ronny (Journal article; Peer reviewed, 2021)Background: Obesity is a frequent somatic comorbidity of major depression, and it has been associated with worse clinical outcomes and brain structural abnormalities. Converging evidence suggests that electroconvulsive ... -
The human amygdala encodes value and space during decision making
Ousdal, Olga Therese; Specht, Karsten; Server, Andres; Andreassen, Ole Andreas; Dolan, Ray J.; Jensen, Jimmy Kristian (Peer reviewed; Journal article, 2014-11-01)Valuable stimuli are invariably localized in space. While our knowledge regarding the neural networks supporting value assignment and comparisons is considerable, we lack a basic understanding of how the human brain ... -
Inhibitory control as possible risk and/or resilience factor for the development of trauma related symptoms–a study of the Utøya terror attack survivors
Hammar, Åsa Karin; Schmid, Marit Therese; Petersdotter, Linn; Ousdal, Olga Therese; Milde, Anne Marita (Journal article; Peer reviewed, 2023)PTSD symptomatology is known to be associated with executive dysfunction. Inhibitory control is a core component of executive functioning, and inhibitory skills are essential both for adequate functioning in everyday life ... -
Linking resting state metabolite concentrations in the dorsal anterior cingulate cortex to response inhibition in OCD, a combined fMRI-MRS study
de Joode, Niels T.; Thorsen, Anders Lillevik; Vriend, Chris; Pouwels, Petra J.W.; van Balkom, Anton J.L.M.; Hagen, Kristen; Ousdal, Olga Therese; Hansen, Bjarne Kristian Aaslie; Kvale, Gerd; van den Heuvel, Odile A (Journal article; Peer reviewed, 2023)Introduction Obsessive-compulsive disorder (OCD) has been associated with abnormal brain activation in regions related to response inhibition, such as the dorsal anterior cingulate cortex (dACC), as well as dysregulation ... -
Longitudinal changes in neurometabolite concentrations in the dorsal anterior cingulate cortex after concentrated exposure therapy for obsessive-compulsive disorder
de Joode, Niels T.; Thorsen, Anders Lillevik; Vester, Eline L.; Vriend, Chris; Pouwels, Petra J.W.; Hagen, Kristen; Ousdal, Olga Therese; Hansen, Bjarne Kristian Aaslie; Kvale, Gerd; van den Heuvel, Odile A. (Journal article; Peer reviewed, 2021)Background The dorsal anterior cingulate cortex (dACC) plays an important role in the pathophysiology of obsessive-compulsive disorder (OCD) due to its role in error processing, cognitive control and emotion regulation. ... -
Longitudinal resting-state network connectivity changes in electroconvulsive therapy patients compared to healthy controls
Verdijk, Joey P. A. J.; van de Mortel, Laurens A.; ten Doesschate, Freek; Pottkämper, Julia C.M.; Stuiver, Sven; Bruin, Willem B.; Abbott, Christopher C.; Argyelan, Miklos; Ousdal, Olga Therese; Bartsch, Hauke; Narr, Katherine; Tendolkar, Indira; Calhoun, Vince; Lukemire, Joshua; Guo, Ying; Oltedal, Leif; van Wingen, Guido; van Waarde, Jeroen A. (Journal article; Peer reviewed, 2024)Objective Electroconvulsive therapy (ECT) is effective for major depressive episodes. Understanding of underlying mechanisms has been increased by examining changes of brain connectivity but studies often do not correct ... -
Longitudinal stability of the brain functional connectome is associated with episodic memory performance in aging
Ousdal, Olga Therese; Kaufmann, Tobias; Kolskår, Knut-Kristian; Vik, Alexandra; Wehling, Eike; Lundervold, Astri; Lundervold, Arvid; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2020)The brain functional connectome forms a relatively stable and idiosyncratic backbone that can be used for identification or “fingerprinting” of individuals with a high level of accuracy. While previous cross‐sectional ... -
Neural Substrates of Psychotic Depression: Findings From the Global ECT-MRI Research Collaboration
Takamiya, Akihiro; Dols, Annemiek; Emsell, Louise; Abbott, Christopher; Yrondi, Antoine; Soriano-Mas, Carles; Jørgensen, Martin Balslev; Nordanskog, Pia; Rhebergen, Didi; van Exel, Eric; Oudega, Mardien L.; Bouckaert, Filip; Vandenbulcke, Mathieu; Sienaert, Pascal; Péran, Patrice; Cano, Marta; Cardoner, Narcis; Jørgensen, Anders; Paulson, Olaf B.; Hamilton, Paul; Kampe, Robin; Bruin, Willem; Bartsch, Hauke; Ousdal, Olga Therese; Kessler, Ute; van Wingen, Guido; Oltedal, Leif; Kishimoto, Taishiro (Journal article; Peer reviewed, 2021)Psychotic major depression (PMD) is hypothesized to be a distinct clinical entity from nonpsychotic major depression (NPMD). However, neurobiological evidence supporting this notion is scarce. The aim of this study is to ... -
The Neurobiological Effects of Electroconvulsive Therapy Studied Through Magnetic Resonance: What Have We Learned, and Where Do We Go?
Ousdal, Olga Therese; Brancati, Giulio E.; Kessler, Ute; Erchinger, Vera; Dale, Anders M.; Abbott, Christopher; Oltedal, Leif (Journal article; Peer reviewed, 2021)Electroconvulsive therapy (ECT) is an established treatment choice for severe, treatment-resistant depression, yet its mechanisms of action remain elusive. Magnetic resonance imaging (MRI) of the human brain before and ... -
Neurobiological mechanisms of ECT and TMS treatment in depression: study protocol of a multimodal magnetic resonance investigation
Frid, Leila Marie; Kessler, Ute; Ousdal, Olga Therese; Hammar, Åsa Karin; Haavik, Jan; Riemer, Frank; Hirnstein, Marco; Ersland, Lars; Erchinger, Vera Jane; Ronold, Eivind Haga; Nygaard, Gyrid; Jakobsen, Petter; Craven, Alexander R.; Osnes, Berge; Alisauskiene, Renata; Bartsch, Hauke; Hellard, Stephanie Francoise Claire Le; Stavrum, Anne-Kristin Støbakk; Oedegaard, Ketil J.; Oltedal, Leif (Journal article; Peer reviewed, 2023)Background: Noninvasive neurostimulation treatments are increasingly being used to treat major depression, which is a common cause of disability worldwide. While electroconvulsive therapy (ECT) and transcranial magnetic ... -
Neurobiological mechanisms of electroconvulsive therapy for depression: Insights into hippocampal volumetric increases from clinical and preclinical studies
Abe, Yoshifumi; Erchinger, Vera Jane; Ousdal, Olga Therese; Oltedal, Leif; Tanaka, Kenji F.; Takamiya, Akihiro (Journal article; Peer reviewed, 2024)Depression is a highly prevalent and disabling psychiatric disorder. The hippocampus, which plays a central role in mood regulation and memory, has received considerable attention in depression research. Electroconvulsive ... -
Short and long-term effects of single and multiple sessions of electroconvulsive therapy on brain gray matter volumes
Brancati, Giulio Emilio; Brekke, Njål; Bartsch, Hauke; Sørhaug, Ole Johan Evjenth; Ousdal, Olga Therese; Hammar, Åsa Karin; Schuster, Peter Moritz; Ødegaard, Ketil Joachim; Kessler, Ute; Oltedal, Leif (Journal article; Peer reviewed, 2021)Background: Electroconvulsive therapy (ECT) has been shown to induce broadly distributed cortical and subcortical volume increases, more prominently in the amygdala and the hippocampus. Structural changes after one ECT ...