• Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip fracture patients 

      Watne, Leiv Otto; Pollmann, Christian Thomas; Neerland, Bjørn Erik; Quist-Paulsen, Else; Halaas, Nathalie Bodd; Idland, Ane-Victoria; Hassel, Bjørnar; Henjum, Kristi; Knapskog, Anne Brita; Frihagen, Frede; Ræder, Johan; Godø, Aasmund; Ueland, Per Magne; McCann, Adrian; Figved, Paul Wender; Selbæk, Geir; Zetterberg, Henrik; Fei Fang, Evandro; Myrstad, Marius; Giil, Lasse Melvær (Journal article; Peer reviewed, 2022)
      Background: The kynurenine pathway (KP) has been identified as a potential mediator linking acute illness to cognitive dysfunction by generating neuroactive metabolites in response to inflammation. Delirium (acute confusion) ...
    • Fast track hip fracture care and mortality – an observational study of 2230 patients 

      Pollmann, Christian Thomas; Røtterud, Jan H; Gjertsen, Jan-Erik; Dahl, Fredrik Andreas; Lenvik, Olav; Årøen, Asbjørn (Peer reviewed; Journal article, 2019-05-24)
      Background: Hip fracture patients are frail and have a high mortality. We investigated whether the introduction of fast track care reduced the 30-day mortality after hip fractures. Methods: Fast track hip fracture care was ...
    • Impaired glucose utilization in the brain of patients with delirium following hip fracture 

      Titlestad, Irit; Watne, Leiv; Caplan, Gideon A.; McCann, Adrian; Ueland, Per Magne; Neerland, Bjørn Erik; Myrstad, Marius; Halaas, Nathalie Bodd; Pollmann, Christian Thomas; Henjum, Kristi; Ranhoff, Anette Hylen; Solberg, Lene Bergendal; Figved, Wender; Cunningham, Colm; Melvær, Giil Lasse (Journal article; Peer reviewed, 2024)
      Alterations in brain energy metabolism have long been proposed as one of several neurobiological processes contributing to delirium. This is supported by previous findings of altered CSF lactate and neuron-specific enolase ...
    • Surgical site infection after hip fracture – mortality and risk factors: an observational cohort study of 1,709 patients 

      Pollmann, Christian Thomas; Dahl, Fredrik Andreas; Årøen, Asbjørn; Røtterud, Jan Harald M; Gjertsen, Jan-Erik (Journal article; Peer reviewed, 2020)
      Background and purpose — Surgical site infection (SSI) is a devastating complication of hip fracture surgery. We studied the contribution of early deep SSI to mortality after hip fracture surgery and the risk factors for ...