Browsing Bergen Open Research Archive by Author "Rauch, Pia"
Now showing items 1-2 of 2
-
Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly
Votteler, Jörg; Neumann, Liane; Hahn, Sabine; Hahn, Friedrich; Rauch, Pia; Schmidt, Kerstin; Studtrucker, Nicole; Solbak, Sara Marie Øie; Fossen, Torgils; Henklein, Peter; Ott, David E.; Holland, Gudrun; Bannert, Norbert; Schubert, Ulrich (Peer reviewed; Journal article, 2011-02-16)Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ... -
Mutation of the highly conserved ser-40 of the HIV-1 p6 gag protein to phe causes the formation of a hydrophobic patch, enhances membrane association, and polyubiquitination of gag
Hahn, Friedrich; Setz, Christian; Friedrich, Melanie; Rauch, Pia; Solbak, Sara Marie Øie; Frøystein, Nils Åge; Henklein, Petra; Votteler, Jörg; Fossen, Torgils; Schubert, Ulrich (Peer reviewed; Journal article, 2014-10-02)The HIV-1 p6 Gag protein contains two late assembly (l-) domains that recruit proteins of the endosomal sorting complex required for transport (ESCRT) pathway to mediate membrane fission between the nascent virion and the ...