Blar i Bergen Open Research Archive på forfatter "Sønnesyn, Hogne"
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Benzodiazepines and antidepressants: Effects on cognitive and functional decline in Alzheimer's disease and Lewy body dementia
Borda, Miguel Germán; Jaramillo-Jiménez, Alberto; Oesterhus, Ragnhild; Santacruz, José Manuel; Tovar-Rios, Diego Alejandro; Sønnesyn, Hogne; Cano-Gutierrez, Carlos Alberto; Vik‐Mo, Audun Osland; Aarsland, Dag (Journal article; Peer reviewed, 2021-12-31)Objectives We aim to study the effects of the prescription of benzodiazepines and antidepressants on cognitive and functional decline in older adults living with Alzheimer's disease (AD) and Lewy body dementia (LBD) over ... -
Effects of anthocyanin supplementation on serum lipids, glucose, markers of inflammation and cognition in adults with increased risk of dementia - A pilot study
Bergland, Anne Katrine; Sønnesyn, Hogne; Dalen, Ingvild; Rodriguez-Mateos, Ana; Berge, Rolf Kristian; Melvær, Giil Lasse; Rajendran, Lawrence; Siow, Richard; Tassotti, Michele; Larsen, Alf Inge; Aarsland, Dag (Peer reviewed; Journal article, 2019-06-11)Background: Anthocyanins may protect against cardiovascular related cognitive decline and dementia. Objective: Open-label study to measure changes in serum lipids, glucose, glycosylated hemoglobin (HbA1c), and markers of ... -
Effects of purified anthocyanins in people at risk for dementia: Study protocol for a phase II randomized controlled trial
Khalifa, Khadija; Bergland, Anne Katrine; Sønnesyn, Hogne; Oppedal, Ketil; Oesterhus, Ragnhild; Dalen, Ingvild; Larsen, Alf Inge; Fladby, Tormod; Brooker, Helen; Wesnes, Keith A.; Ballard, Clive; Aarsland, Dag (Journal article; Peer reviewed, 2020)Background: The number of people with dementia is increasing, with huge challenges for society and health-care systems. There are no disease-modifying therapies available. There is, therefore, an urgent need to identify ... -
Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease
Borda, Miguel Germán; Sønnesyn, Hogne; Steves, Claire J.; Vik-Mo, Audun Osland; Perez-Zepeda, Mario Ulises; Årsland, Dag (Peer reviewed; Journal article, 2019)Introduction: The aim of the study is to describe the frequency of frailty in people with a new diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Methods: This is a secondary ... -
Frequency and prognostic implications of orthostatic hypotension and white matter hyperintensities in older people with mild dementia
Sønnesyn, Hogne (Doctoral thesis, 2014-09-19)Background: In addition to cognitive impairments, dementia sufferers may have other problems as well, such as depression and orthostatic hypotension (OH), both of which according to previous studies may be associated with ... -
High prevalence of orthostatic hypotension in mild dementia
Sønnesyn, Hogne; Nilsen, Dennis W. T.; Rongve, Arvid; Nore, Sabine; Ballard, Clive; Tysnes, Ole-Bjørn; Aarsland, Dag (Peer reviewed; Journal article, 2009-11)Background/Aims: Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia. Methods: Patients with mild ... -
Persistence and Prognostic Implications of Orthostatic Hypotension in Older Individuals with Mild-to-Moderate Dementia
Sønnesyn, Hogne; Dalen, Ingvild; Aarsland, Dag (Peer reviewed; Journal article, 2014)Aim: To study the course and prognostic implications of orthostatic hypotension (OH) in older individuals with mild-to-moderate dementia. Methods: Referrals to outpatient clinics specialising in old age psychiatry and ... -
A Randomised Placebo-Controlled Study of Purified Anthocyanins on Cognition in Individuals at Increased Risk for Dementia
Aarsland, Dag; Khalifa, Khadija; Bergland, Anne Katrine; Sønnesyn, Hogne; Oppedal, Ketil; Holteng, Lise Birgitte Austbø; Oesterhus, Ragnhild; Nakling, Arne; Jarholm, Jonas Alexander; de Lucia, Chiara; Fladby, Tormod; Brooker, Helen; Dalen, Ingvild; Ballard, Clive (Journal article; Peer reviewed, 2023)Importance Identifying nutritional compounds which can reduce cognitive decline in older people is a hugely important topic. Objective To study the safety and effect of anthocyanins in maintaining cognitive functioning ... -
Relationship between Orthostatic Hypotension and White Matter Hyperintensity Load in Older Patients with Mild Dementia
Sønnesyn, Hogne; Nilsen, Dennis W. T.; Oppedal, Ketil; Greve, Ole Jacob; Beyer, Mona K.; Aarsland, Dag (Peer reviewed; Journal article, 2012-12-19)Background/Objectives: White matter hyperintensities (WMH) in magnetic resonance imaging (MRI) scans of the brain, and orthostatic hypotension (OH) are both common in older people. We tested the hypothesis that OH is ... -
Specific neuropsychiatric symptoms are associated with functional decline trajectories in Alzheimer’s disease and Lewy body dementia: a five-year follow-up study
Borda, Miguel Germán; Brønnick, Kolbjørn Kallesten; Garcia-Cifuentes, Elkin; Jaramillo-Jiménez, Alberto; Reyes-Ortiz, Carlos; Patricio-Baldera, Jonathan; Sønnesyn, Hogne; Pérez-Zepeda, Mario Ulises; Vik-Mo, Audun Osland; Aarsland, Dag (Journal article; Peer reviewed, 2023-10-17)Background: Neuropsychiatric symptoms (NPS) are often overlooked and under-identified symptoms associated with dementia, despite their significant impact on the prognosis of individuals living with the disease. The specific ... -
White Matter Hyperintensities and the Course of Depressive Symptoms in Elderly People with Mild Dementia
Sønnesyn, Hogne; Oppedal, Ketil; Greve, Ole Jacob; Fritze, Friederike; Auestad, Bjørn Henrik; Nore, Sabine; Beyer, Mona K.; Aarsland, Dag (Peer reviewed; Journal article, 2012)Objectives: To explore the relationship between white matter hyperintensities (WMH) and the prevalence and course of depressive symptoms in mild Alzheimer’s disease (AD) and Lewy body dementia. Design: This is a prospective ...