Browsing Bergen Open Research Archive by Author "Sapkota, Dipak"
Now showing items 1-10 of 10
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Accessing the prior knowledge and teaching a heterogeneous class of dental hygienist
Sapkota, Dipak (UPED-skrift, Working paper, 2017) -
Adenoviral Mediated Expression of BMP2 by Bone Marrow Stromal Cells cultured in 3D Copolymer Scaffolds Enhances Bone Formation
Sharma, Sunita; Sapkota, Dipak; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Bruland, Ove; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2016-01-25)Selection of appropriate osteoinductive growth factors, suitable delivery method and proper supportive scaffold are critical for a successful outcome in bone tissue engineering using bone marrow stromal cells (BMSC). This ... -
Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect
Sharma, Sunita; Xue, Ying; Xing, Zhe; Yassin, Mohammed Ahmed; Sun, Yang; Lorens, James; Finne-Wistrand, Anna; Sapkota, Dipak; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2019-04-11)Apart from osteogenesis, neovascularization of the defect area is an important determinant for successful bone healing. Accordingly, several studies have employed the combined delivery of VEGFA and BMP2 for bone regeneration. ... -
Benefit from B-Lymphocyte Depletion Using the Anti- CD20 Antibody Rituximab in Chronic Fatigue Syndrome. A Double-Blind and Placebo-Controlled Study
Fluge, Øystein; Bruland, Ove; Risa, Kristin; Storstein, Anette; Kristoffersen, Einar K.; Sapkota, Dipak; Næss, Halvor; Dahl, Olav; Nyland, Harald; Mella, Olav (Peer reviewed; Journal article, 2011-10-19)Background: Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS symptom relief during cancer chemotherapy in a patient with synchronous CFS and lymphoma spurred a pilot study of B-lymphocyte depletion ... -
Delivery of VEGFA in bone marrow stromal cells seeded in copolymer scaffold enhances angiogenesis, but is inadequate for osteogenesis as compared with the dual delivery of VEGFA and BMP2 in a subcutaneous mouse model
Sharma, Sunita; Sapkota, Dipak; Xue, Ying; Rajthala, Saroj; Yassin, Mohammed Ahmed Alamin Yousif; Finne-Wistrand, Anna; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2018-01-31)Background: In bone tissue engineering (BTE), extensive research into vascular endothelial growth factor A (VEGFA)-mediated angiogenesis has yielded inconsistent results. The aim of this study was to investigate the influence ... -
The Low Affinity Nerve Growth Factor Receptor p75NTR Identifies a Transient Stem Cell-Like State in Oral Squamous Cell Carcinoma Cells
Osman, Tarig Al-Hadi; Costea, Daniela Elena; Parajuli, Himalaya; Sapkota, Dipak; Johannessen, Anne Christine; Ahmed, Israa A. H. (Peer reviewed; Journal article, 2014-09-12)Background Although several markers have been used for enrichment of cells with stem cell-like properties in oral squamous cell carcinoma (OSCC), isolation of a pure subpopulation is still a challenging task. Normal oral ... -
MicroRNAs as important players and biomarkers in oral carcinogenesis
Min, Anjie; Zhu, Chao; Peng, Shuping; Rajthala, Saroj; Costea, Daniela Elena; Sapkota, Dipak (Peer reviewed; Journal article, 2015)Oral cancer, represented mainly by oral squamous cell carcinoma (OSCC), is the eighth most common type of human cancer worldwide. The number of new OSCC cases is increasing worldwide, especially in the low-income countries, ... -
Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.
Liang, Xiao; Osman, Tarig Al-Hadi; Sapkota, Dipak; Neppelberg, Evelyn; Lybak, Stein; Liavaag, Per Gunnar; Johannessen, Anne Christine; Jacobsen, Hege Karine; Enger, Per Øyvind; Costea, Daniela Elena; Wang, Jian (Peer reviewed; Journal article, 2014-12)Background: Although several approaches for identification and isolation of carcinoma cells with tumour initiating properties have been established, enrichment of a population of pure and viable tumour-initiating cells ... -
S100 gene family members in oral squamous cell carcinomas (OSCCs): Functional characterization of S100A14 in proliferation and invasion of OSCC derived cells
Sapkota, Dipak (Doctoral thesis, 2011-01-21) -
S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma
Sapkota, Dipak; Bruland, Ove; Parajuli, Himalaya; Osman, Tarig Al-Hadi; Teh, Muy-Teck; Johannessen, Anne Christine; Costea, Daniela Elena (Peer reviewed; Journal article, 2015-09-09)Background: Altered expression of S100A16 has been reported in human cancers, but its biological role in tumorigenesis is not fully understood. This study aimed to investigate the clinical significance and functional role ...