Blar i Bergen Open Research Archive på forfatter "Trieu, Mai Chi"
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Attack rates amongst household members of outpatients with confirmed COVID-19 in Bergen, Norway: A case-ascertained study
Kuwelker, Kanika; Zhou, Fan; Blomberg, Bjørn; Jalloh, Sarah Larteley Lartey; Brokstad, Karl Albert; Trieu, Mai Chi; Bansal, Amit; Madsen, Anders; Krammer, Florian; Mohn, Kristin Greve-Isdahl; Tøndel, Camilla; Linchausen, Dagrunn Waag; Cox, Rebecca Jane; Langeland, Nina (Journal article; Peer reviewed, 2021)Background Households studies reflect the natural spread of SARS-CoV-2 in immunologically naive populations with limited preventive measures to control transmission. We hypothesise that seropositivity provides more ... -
Augmented CD4+ T-cell and humoral responses after repeated annual influenza vaccination with the same vaccine component A/H1N1pdm09 over 5 years
Trieu, Mai Chi; Zhou, Fan; Jalloh, Sarah Larteley Lartey; Sridhar, Saranya; Mjaaland, Siri; Cox, Rebecca Jane (Peer reviewed; Journal article, 2018-08-14)Annual seasonal influenza vaccination is recommended for high-risk populations and often occupational groups such as healthcare workers (HCWs). Repeated annual vaccination has been reported to either have no impact or ... -
Durable immune responses after BNT162b2 vaccination in home-dwelling old adults
Hansen, Lena; Brokstad, Karl Albert; Bansal, Amit; Zhou, Fan; Bredholt, Geir; Onyango, Therese Bredholt; Sandnes, Helene Heitmann; Elyanow, Rebecca; Madsen, Anders; Trieu, Mai Chi; Sævik, Marianne; Søyland, Hanne; Olofsson, Jan Stefan; Vahokoski, Juha; Ertesvåg, Nina Urke; Fjelltveit, Elisabeth Berg; Shafiani, Shahin; Tøndel, Camilla; Chapman, Heidi; Kaplan, Ian; Mohn, Kristin Greve-Isdahl; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2023)Objectives Elderly are an understudied, high-risk group vulnerable to severe COVID-19. We comprehensively analyzed the durability of humoral and cellular immune responses after BNT162b2 vaccination and SARS-CoV-2 infection ... -
Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014)
Amdam, Håkon; Madsen, Anders; Zhou, Fan; Bansal, Amit; Trieu, Mai Chi; Cox, Rebecca Jane (Journal article; Peer reviewed, 2021)Background: In 2009, a novel influenza A/H1N1pdm09 emerged and caused a pandemic. This strain continued to circulate and was therefore included in the seasonal vaccines up to the 2016/2017-season. This provided a unique ... -
Harmonization and qualification of an IFN-γ Enzyme-Linked ImmunoSpot assay (ELISPOT) to measure influenza-specific cell-mediated immunity within the FLUCOP consortium
Waerlop, Gwenn; Leroux-Roels, Geert; Lambe, Teresa; Bellamy, Duncan; Medaglini, Donata; Pettini, Elena; Cox, Rebecca Jane; Trieu, Mai Chi; Davies, Richard Allan; Bredholt, Geir; Montomoli, Emanuele; Gianchecchi, Elena; Clement, Frédéric (Journal article; Peer reviewed, 2022-09-08)Influenza continues to be the most important cause of viral respiratory disease, despite the availability of vaccines. Today’s evaluation of influenza vaccines mainly focuses on the quantitative and functional analyses of ... -
High prevalence of humoral and cellular immunity to influenza viruses in pre-school children living in Addis Ababa, Ethiopia
Dembinski, Jennifer Lynn; Mihret, Adane; Yimer, Solomon Abebe; Tessema, Bamlak; Trieu, Mai Chi; Tarekegn, Azeb; Getachew, Nahom; Cox, Rebecca Jane; Oftung, Fredrik; Haneberg, Bjørn; Aseffa, Abraham; Mjaaland, Siri (Peer reviewed; Journal article, 2017-01)Background. Influenza in children who reside in tropical and subtropical regions has until recently been regarded as insignificant. However, new evidence suggests that it significantly impacts hospitalization and promotes ... -
Live attenuated influenza vaccine in children induces b-cell responses in tonsils
Mohn, Kristin Greve-Isdahl; Brokstad, Karl Albert; Pathirana, Rishi; Bredholt, Geir; Jul-Larsen, Åsne; Trieu, Mai Chi; Jalloh, Sarah Larteley Lartey; Montemoli, Emanuele; Tøndel, Camilla; Aarstad, Hans Jørgen; Cox, Rebecca Jane (Peer reviewed; Journal article, 2016)Background. Tonsils play a key role in eliciting immune responses against respiratory pathogens. Little is known about how tonsils contribute to the local immune response after intranasal vaccination. Here, we uniquely ... -
The Performances of Three Commercially Available Assays for the Detection of SARS‐CoV‐2 Antibodies at Different Time Points Following SARS‐CoV‐2 Infection
Syre, Heidi; Obreque, Marius Eduardo Brå; Dalen, Ingvild; Riis, Åse Garløv; Berg, Åse; Löhr, Iren Høyland; Sundal, Jon; Kleppe, Lars Kåre Selland; Vadla, May Sissel; Lenning, Ole Bernt; Olofsson, Jan Stefan; Mohn, Kristin Greve-Isdahl; Tøndel, Camilla; Blomberg, Bjørn; Trieu, Mai Chi; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2022)The aim of this study was to evaluate the performances of three commercially available antibody assays for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies at different time points ... -
Persistently high antibody responses after AS03-adjuvanted H1N1pdm09 vaccine: Dissecting the HA specific antibody response
Madsen, Anders; Jul-Larsen, Åsne; Trieu, Mai Chi; Krammer, Florian; Cox, Rebecca Jane (Journal article; Peer reviewed, 2021)Current influenza vaccines have a suboptimal effectiveness. The introduction of a novel A/H1N1 influenza virus in 2009 (H1N1pdm09) provided a unique opportunity to study the humoral response to the AS03-adjuvanted H1N1pdm09 ... -
A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern
Ertesvåg, Nina Urke; Xiao, Julie; Zhou, Fan; Ljostveit, Sonja; Sandnes, Helene Heitmann; Lartey, Sarah; Sævik, Marianne; Hansen, Lena; Madsen, Anders; Mohn, Kristin Greve-Isdahl; Fjelltveit, Elisabeth Berg; Olofsson, Jan Stefan; Tan, Tiong Kit; Rijal, Pramilia; Schimanski, Lisa; Øyen, Siri; Brokstad, Karl Albert; Dunachie, Susanna; Jämsén, Anni; James, William S.; Harding, Adam C.; Harvala, Heli; Nguyen, Dung; Roberts, David; Patel, Monika; Gopal, Robin; Zambon, Maria; Wei, Leiyan; Gilbert-Jaramillo, Javier; Knight, Michael L.; Vaughan-Jackson, Alun; Dupont, Maeva; Lamikanra, Abigail A.; Klennerman, Paul; Townsend, Alain; Tøndel, Camilla; Kuwelker, Kanika; Blomberg, Bjørn; Bredholt, Geir; Onyango, Therese Bredholt; Vahokoski, Juha; Bansal, Amit; Trieu, Mai Chi; Amdam, Håkon; Akselsen, Per Espen; Skorge, Trude Duelien; Okkenhaug, Liv Heiberg; Linchausen, Dagrun Waag; Langeland, Nina; Cox Brokstad, Rebecca Jane (Journal article; Peer reviewed, 2022)Background: Evaluation of susceptibility to emerging SARS-CoV-2 variants of concern (VOC) requires rapid screening tests for neutralising antibodies which provide protection. Methods: Firstly, we developed a receptor-binding ... -
Repeated Influenza Vaccination Boosts and Maintains H1N1pdm09 Neuraminidase Antibody Titers
Hansen, Lena; Zhou, Fan; Amdam, Håkon; Trieu, Mai Chi; Cox, Rebecca Jane (Journal article; Peer reviewed, 2021)Antibodies to influenza surface protein neuraminidase (NA) have been found to reduce disease severity and may be an independent correlate of protection. Despite this, current influenza vaccines have no regulatory requirements ... -
Risk assessment and antibody responses to SARS-CoV-2 in healthcare workers
Bansal, Amit; Trieu, Mai Chi; Mohn, Kristin Greve-Isdahl; Madsen, Anders; Olofsson, Jan Stefan; Sandnes, Helene Heitmann; Sævik, Marianne; Søyland, Hanne; Hansen, Lena; Onyango, Therese Bredholt; Tøndel, Camilla; Brokstad, Karl Albert; Syre, Heidi; Riis, Åse Garløv; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2023)Background: Preventing infection in healthcare workers (HCWs) is crucial for protecting healthcare systems during the COVID-19 pandemic. Here, we investigated the seroepidemiology of SARS-CoV-2 in HCWs in Norway with ... -
Safety, Immunogenicity, Efficacy and Effectiveness of Inactivated Influenza Vaccines in Healthy Pregnant Women and Children Under 5 Years: An Evidence-Based Clinical Review
Bansal, Amit; Trieu, Mai Chi; Mohn, Kristin Greve-Isdahl; Cox, Rebecca Jane (Journal article; Peer reviewed, 2021)Annual influenza vaccination is often recommended for pregnant women and young children to reduce the risk of severe influenza. However, most studies investigating the safety, immunogenicity, and efficacy or effectiveness ... -
SARS-CoV-2–Specific Neutralizing Antibody Responses in Norwegian Health Care Workers After the First Wave of COVID-19 Pandemic: A Prospective Cohort Study
Trieu, Mai Chi; Bansal, Amit; Madsen, Anders; Zhou, Fan; Sævik, Marianne; Vahokoski, Juha; Brokstad, Karl Albert; Krammer, Florian; Tøndel, Camilla; Mohn, Kristin Greve-Isdahl; Blomberg, Bjørn; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2021)Background During the coronavirus disease 2019 (COVID-19) pandemic, many countries experienced infection in health care workers (HCW) due to overburdened health care systems. Whether infected HCW acquire protective immunity ... -
Seasonal influenza vaccination expands hemagglutinin-specific antibody breadth to older and future A/H3N2 viruses
Ertesvåg, Nina Urke; Cox, Rebecca Jane; Jalloh, Sarah Larteley Lartey; Mohn, Kristin Greve-Isdahl; Brokstad, Karl Albert; Trieu, Mai Chi (Journal article; Peer reviewed, 2022)History of influenza A/H3N2 exposure, especially childhood infection, shape antibody responses after influenza vaccination and infection, but have not been extensively studied. We investigated the breadth and durability ... -
Vaccination prevents severe COVID-19 outcome in patients with neutralizing type 1 interferon autoantibodies
Wolff, Anette Susanne Bøe; Hansen, Lena; Grytaas, Marianne Aardal; Oftedal, Bergithe Eikeland; Breivik, Lars Ertesvåg; Zhou, Fan; Hufthammer, Karl Ove; Sjøgren, Thea; Olofsson, Jan Stefan; Trieu, Mai Chi; Meager, Anthony; Jørgensen, Anders Palmstrøm; Lima, Kari; Mohn, Kristin Greve-Isdahl; Langeland, Nina; Cox Brokstad, Rebecca Jane; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2023)A hallmark of patients with autoimmune polyendocrine syndrome type 1 (APS-1) is serological neutralizing autoantibodies against type 1 interferons (IFN-I). The presence of these antibodies has been associated with severe ... -
Vitamin D Deficiency is Associated with Increased Use of Antimicrobials among Preschool Girls in Ethiopia
Bodin, Johanna Eva; Mihret, Adane; Holm-Hansen, Carol J C; Dembinski, Jennifer Lynn; Trieu, Mai Chi; Tessema, Bamlak; Tarekegne, Azeb; Yimer, Solomon Abebe; Cox, Rebecca Jane; Aseffa, Abraham; Haneberg, Bjørn; Mjaaland, Siri (Peer reviewed; Journal article, 2019-03-07)Preschool children in Addis Ababa, Ethiopia, are highly exposed to influenza viruses. Factors related to infections, nutrition, and environmental conditions that might explain the burden of influenza among these children ...