• 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy 

      Joubert, Bonnie R.; Håberg, Siri Eldevik; Nilsen, Roy Miodini; Wang, Xuting; Vollset, Stein Emil; Murphy, Susan K; Huang, Zhiqing; Hoyo, Cathrine; Midttun, Øivind; Cupul-Uicab, Lea A; Ueland, Per Magne; Wu, Michael C; Nystad, Wenche; Bell, Douglas A; Peddada, Shyamal D; London, Stephanie J (Peer reviewed; Journal article, 2012-10)
      Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple ...
    • Alcohol-attributed disease burden in four Nordic countries: a comparison using the Global Burden of Disease, Injuries and Risk Factors 2013 study 

      Agardh, Emilie Elisabet; Danielsson, Anna-Karin; Ramstedt, Mats; Ledgaard Holm, Astrid; Diderichsen, Finn; Juel, Knud; Vollset, Stein Emil; Knudsen, Ann Kristin; Kinge, Jonas Minet; White, Richard; Skirbekk, Vegard; Mäkelä, Pia; Forouzanfar, Mohammad Hossein; Coates, Matthew M.; Casey, Daniel C.; Naghavi, Mohesen; Allebeck, Peter (Peer reviewed; Journal article, 2016-10)
      Aims: (1) To compare alcohol-attributed disease burden in four Nordic countries 1990–2013, by overall disability-adjusted life years (DALYs) and separated by premature mortality [years of life lost (YLL)] and health loss ...
    • Alcohol‐attributed disease burden in four Nordic countries between 2000 and 2017: Are the gender gap s narrowing? A comparison using the Global Burden of Disease, Injury and Risk Factor 2017 study 

      Agardh, Emilie, E.; Allebeck, Peter; Flodin, Pär; Wenneberg, Peter; Ramstedt, Mats; Knudsen, Ann Kristin; Øverland, Simon Nygaard; Kinge, Jonas Minet; Tollånes, Mette C.; Eikemo, Terje Andreas; Skogen, Jens Christoffer; Mäkelä, Pia; Gissler, Mika; Juel, Knud; Iburg, Kim Moesgaard; McGrath, John J.; Naghavi, Mohsen; Vollset, Stein Emil; Gakidou, Emmanuela; Danielsson, Anna-Karin (Journal article; Peer reviewed, 2020)
      Introduction and Aims The gender difference in alcohol use seems to have narrowed in the Nordic countries, but it is not clear to what extent this may have affected differences in levels of harm. We compared gender ...
    • Are the Norwegian health research investments in line with the disease burden? 

      Kinge, Jonas Minet; Roxrud, Ingrid; Vollset, Stein Emil; Skirbekk, Vegard; Røttingen, John-Arne (Peer reviewed; Journal article, 2014-11-27)
      Background: The relationship between research funding across therapeutic areas and the burden of disease in Norway has not been investigated. Further, few studies have looked at the association between national research ...
    • Association Between Maternal Folic Acid Supplementation and Congenital Heart Defects in Offspring in Birth Cohorts From Denmark and Norway 

      Øyen, Nina; Olsen, Sjurdur Frodi; Basit, Saima; Leirgul, Elisabeth; Strøm, Marin; Carstensen, Lisbeth; Granström, Charlotta; Tell, Grethe S.; Magnus, Per; Vollset, Stein Emil; Wohlfart, Jan; Melbye, Mads (Peer reviewed; Journal article, 2019-03-19)
      Background: Evidence linking individual‐level maternal folic acid supplementation to offspring risk of congenital heart defects is lacking. We investigated whether folic acid supplementation in early pregnancy reduces ...
    • Association of Household Income With Life Expectancy and Cause-Specific Mortality in Norway, 2005-2015 

      Kinge, Jonas Minet; Modalsli, Jørgen Heibø; Øverland, Simon Nygaard; Gjessing, Håkon K.; Tollånes, Mette Christophersen; Knudsen, Ann Kristin; Skirbekk, Vegard Fykse; Strand, Bjørn Heine; Håberg, Siri Eldevik; Vollset, Stein Emil (Peer reviewed; Journal article, 2019-05-13)
      Importance: Examining causes of death and making comparisons across countries may increase understanding of the income-related differences in life expectancy. Objectives: To describe income-related differences in life ...
    • Birth prevalence of congenital heart defects in Norway 1994-2009—A nationwide study 

      Leirgul, Elisabeth; Fomina, Tatiana; Brodwall, Kristoffer; Greve, Gottfried; Holmstrøm, Henrik; Vollset, Stein Emil; Tell, Grethe Seppola; Øyen, Nina (Peer reviewed; Journal article, 2014-08-10)
      Background The reasons for decreasing birth prevalence of congenital heart defects (CHDs) in several European countries and Canada are not fully understood. We present CHD prevalence among live births, stillbirths, and ...
    • Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study 

      Mokdad, Ali H.; Khalil, Ibrahim; El Bcheraoui, Charbel; Charara, Raghid; Moradi-Lakeh, Maziar; Afshin, Ashkan; Kassebaum, Nicholas J.; Collison, Michael; Chew, Adrienne; Krohn, Kristopher J.; Daoud, Farah; Colombara, Danny; Foreman, Kyle J.; Godwin, William W.; Kutz, Michael; Mirarefin, Mojde; Rao, Puja C.; Reiner, Robert; Troeger, Christopher; Wang, Haidong; Niguse Abraha, Haftom; Abu-Elyazeed, Remon; Abu-Raddad, Laith J.; Ahmad Kiadaliri, Aliasghar; Ahmadi, Alireza; Beshir Ahmed, Muktar; Alam, Khurshid; Alizadeh-Navaei, Reza; Al-Raddadi, Rajaa; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Anber, Nahla; Anwari, Palwasha; Mehari Atey, Tesfay; Avokpaho, Euripide Frinel G. Arthur; Bacha, Umar; Bazargan-Hejazi, Shahrzad; Bedi, Neeraj; Bensenor, Isabela M.; Berhane, Adugnaw; Obong Bessong, Pascal; Shunu Beyene, Addisu; Bhutta, Zulfiqar A.; Colin Buckle, Geoffrey; Butt, Zahid A.; Danawi, Hadi; Deribew, Amare; Djalalinia, Shirin; Dubey, Manisha; Endries, Aman Yesuf; Eshrati, Babak; Fereshtehnejad, Seyed-Mohammad; Fischer, Florian; Tewelde Gebrehiwot, Tsegaye; Chander Gugnani, Harish; Ribhi Hamadeh, Randah; Hamidi, Samer; Husseini, Abdullatif; James, Spencer Lewis; Jonas, Jost B.; Kasaeian, Amir; Saleh Khader, Yousef; Ahmad Khan, Ejaz; Khan, Gulfaraz; Khubchandani, Jagdish; Kissoon, Niranjan; Kopec, Jacek A.; Koyanagi, Ai; Kuate Defo, Barthelemy; Larson, Heidi J.; Abdul Latif, Asma; Lunevicius, Raimundas; Abd El Razek, Hassan Magdy; Abd El Razek, Mohammed Magdy; Majdzadeh, Reza; Majeed, Azeem; Malekzadeh, Reza; Memiah, Peter; Memish, Ziad A.; Mendoza, Walter; Tadese Mengistu, Desalegn; Mohammed, Shafiu; Murthy, Srinivas; Wanjiku Ngunjiri, Josephine; Akpojene Ogbo, Felix; Pourmalek, Farshad; Qorbani, Mostafa; Radfar, Amir; Rafay, Anwar; Rahimi-Movaghar, Vafa; Kumar Rai, Rajesh; Ram, Usha; Laith Rawaf, David; Rawaf, Salman; Renzaho, Andre M.N.; Rezaei, Satar; Roshandel, Gholamreza; Safdarian, Mahdi; Ali Sahraian, Mohammad; Salamati, Payman; Samy, Abdallah M.; Ramon Sanabria, Juan; Sartorius, Benn; Sepanlou, Sadaf G.; Ali Shaikh, Masood; Shigematsu, Mika; Sobaih, Badr H.A.; Sreeramareddy, Chandrashekhar T.; Sykes, Bryan L.; Tehrani-Banihashemi, Arash; Temsah, Mohamad-Hani; Sulieman Terkawi, Abdullah; Tiruye, Tenaw Yimer; Topor-Madry, Roman; Nnanna Ukwaja, Kingsley; Vollset, Stein Emil; Wakayo, Tolassa; Werdecker, Andrea; Shey Wiysonge, Charles; Workicho, Abdulhalik; Yaghoubi, Mohsen; Yaseri, Mehdi; Yenesew, Muluken; Yonemoto, Naohiro; Younis, Mustafa Z.; El Sayed Zaki, Maysaa; Zodpey, Sanjay; Zein, Bassel; Jumaan, Aisha O.; Vos, Theo; Hay, Simon I.; Naghavi, Mohsen; Murray, Christopher J.L. (Peer reviewed; Journal article, 2018-05)
      Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children’s potential livelihood through growth faltering, cognitive impairment, ...
    • Can 'early programming' be partly explained by smoking? Results from a prospective, population-based cohort study 

      Kvalvik, Liv Grimstvedt; Skjaerven, Rolv; Klungsøyr, Kari; Vollset, Stein Emil; Haug, Kjell (Peer reviewed; Journal article, 2015-01)
      Background: Numerous studies have focused the association between low birthweight and later disease. Our objective was to study the association between birthweight and later adult smoking and thereby explore a possible ...
    • Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study 

      Chuang, Shu-Chun; Boeing, Heiner; Vollset, Stein Emil; Midttun, Øivind; Ueland, Per Magne; Bueno-de-Mesquita, Bas; Lajous, Martin; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Kaaks, Rudolf; Küehn, Tilman; Pischon, Tobias; Drogan, Dagmar; Tjønneland, Anne; Overvad, Kim; Quirós, J. Ramón; Agudo, Antonio; Molina-Montes, Esther; Dorronsoro, Miren; Huerta, José María; Barricarte, Aurelio; Khaw, Kay-Tee; Wareham, Nicholas J.; Travis, Ruth C.; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Masala, Giovanna; Agnoli, Claudia; Tumino, Rosario; Mattiello, Amalia; Peeters, Petra H.; Weiderpass, Elisabete; Palmqvist, Richard; Ljuslinder, Ingrid; Gunter, Marc; Lu, Yunxia; Cross, Amanda J.; Riboli, Elio; Vineis, Paolo; Aleksandrova, Krasimira (Peer reviewed; Journal article, 2016-02-25)
      Background: Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). ...
    • Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival 

      Johansson, Mattias; Anouar, Fanidi; Muller, David C.; Bassett, Julie K.; Midttun, Øivind; Vollset, Stein Emil; Travis, Ruth C.; Palli, Domenico; Mattiello, Amalia; Sieri, Sabina; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Ljungberg, Börje; Hallmans, Göran; Weiderpass, Elisabete; Skeie, Guri; Gonzalez, Carlos A.; Dorronsoro, Miren; Peeters, Petra H.; Bueno-de-Mesquita, H. B(as).; Ros, Martine M.; Ruault, Marie-Christine Boutron; Fagherazzi, Guy; Clavel, Françoise; Sanchez, Maria-Jose; Gurrea, Aurelio Barricarte; Navarro, Carmen; Quirós, J. Ramón; Overvad, Kim; Tjønneland, Anne; Aleksandrova, Krassimira; Vineis, Paolo; Gunter, Marc J.; Kaaks, Rudolf; Giles, Graham; Relton, Caroline; Riboli, Elio; Boeing, Heiner; Ueland, Per Magne; Severi, Gianluca; Brennan, Paul (Peer reviewed; Journal article, 2014)
      Background The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival. Methods The ...
    • Circulating Vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort 

      Fanidi, Anouar; Muller, David C.; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Relton, Caroline; Vineis, Paolo; Weiderpass, Elisabete; Skeie, Guri; Brustad, Magritt; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Cadeau, Claire; Huerta, José María; Sánchez, María-José; Agudo, Antonio; Lasheras, Cristina; Quirós, J. Ramón; Chamosa, Saioa; Riboli, Elio; Travis, Ruth C; Ward, Heather; Murphy, Neil; Khaw, Kay-Tee; Trichopoulou, Antonia; Lagiou, Pagona; Papatesta, Eleni-Maria; Boeing, Heiner; Kühn, Tilman; Katzke, Verena; Steffen, Annika; Johansson, Anders; Brennan, Paul; Johansson, Mattias (Peer reviewed; Journal article, 2016-11-04)
      Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective ...
    • Dietary predictors of plasma total homocysteine concentration in the Hordaland Homocysteine Study 

      Konstantinova, Svetlana V.; Vollset, Stein Emil; Berstad, Paula; Ueland, Per Magne; Drevon, Christian A.; Refsum, Helga; Tell, Grethe Seppola (Peer reviewed; Journal article, 2007)
      Established dietary predictors of plasma total homocysteine (tHcy) include folate, riboflavin, and vitamins B6 and B12, while information is scarce regarding other dietary components. The aim of this study was to examine ...
    • Differences in perinatal and infant mortality in high-income countries: Artifacts of birth registration or evidence of true differences? 

      Deb-Rinker, Paromita; León, Juan Andrés; Gilbert, Nicolas L.; Rouleau, Jocelyn; Andersen, Anne-Marie Nybo; Bjarnadóttir, Ragnheiður I.; Gissler, Mika; Mortensen, Laust H.; Skjaerven, Rolv; Vollset, Stein Emil; Zhang, Xun; Shah, Prakesh S.; Sauve, Reg S.; Kramer, Michael S.; Joseph, K.S. (Peer reviewed; Journal article, 2015-09-04)
      Background: Variation in birth registration criteria may compromise international comparisons of fetal and infant mortality. We examined the effect of birth registration practices on fetal and infant mortality rates to ...
    • DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy 

      Reese, Sarah E; Zhao, Shanshan; Wu, Michael C; Joubert, Bonnie R; Parr, Christine Louise; Håberg, Siri Eldevik; Ueland, Per Magne; Nilsen, Roy Miodini; Midttun, Øivind; Vollset, Stein Emil; Peddada, Shyamal D; Nystad, Wenche; London, Stephanie J (Peer reviewed; Journal article, 2017-04)
      Background: Maternal smoking during pregnancy, especially when sustained, leads to numerous adverse health outcomes in offspring. Pregnant women disproportionately underreport smoking and smokers tend to have lower follow-up ...
    • Educational inequalities in acute myocardial infarction incidence in Norway: A nationwide cohort study 

      Igland, Jannicke; Vollset, Stein Emil; Nygård, Ottar; Sulo, Gerhard; Ebbing, Marta; Tell, Grethe Seppola (Peer reviewed; Journal article, 2014-09-04)
      Background Increasing differences in cardiovascular disease (CVD) mortality across levels of education have been reported in Norway. The aim of the study was to investigate educational inequalities in acute myocardial ...
    • Folic acid supplementation, dietary folate intake during pregnancy and risk for spontaneous preterm delivery: a prospective observational cohort study 

      Sengpiel, Verena; Bacelis, Jonas; Myhre, Ronny; Myking, Solveig; Pay, Aase Serine Devold; Haugen, Margaretha; Brantsæter, Anne Lise; Meltzer, Helle Margrethe; Nilsen, Roy Miodini; Magnus, Per; Vollset, Stein Emil; Nilsson, Staffan; Jacobsson, Bo (Peer reviewed; Journal article, 2014-11-02)
      Background: Health authorities in numerous countries recommend periconceptional folic acid supplementation to prevent neural tube defects. The objective of this study was to examine the association of dietary folate intake ...
    • Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016 

      Naghavi, Mohsen; Abajobir, Amanuel Alemu; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abera, Semaw Ferede; Aboyans, Victor; Adetokunboh, Olatunji; Ärnlöv, Johan; Afshin, Ashkan; Agrawal, Anurag; Kiadaliri, Aliasghar Ahmad; Ahmadi, Alireza; Ahmed, Muktar Beshir; Aichour, Amani Nidhal; Aichour, Ibtihel; Aichour, Miloud Taki Eddine; Aiyar, Sneha; Al-Eyadhy, Ayman; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore; Alam, Tahiya; Alene, Kefyalew Addis; Ali, Syed Danish; Alizadeh-Navaei, Reza; Alkaabi, Juma M.; Alkerwi, Ala'a; Alla, Francois; Allebeck, Peter; Allen, Christine; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Amare, Azmeraw T.; Amini, Erfan; Ammar, Walid; Amoako, Yaw Ampem; Anber, Nahla; Andersen, Hjalte H.; Andrei, Catalina Liliana; Androudi, Sofia; Ansari, Hossein; Antonio, Carl Abelardo T.; Anwari, Palwasha; Arora, Megha; Artaman, Al; Aryal, Krishna Kumar; Asayesh, Hamid; Asgedom, Solomon W.; Atey, Tesfay Mehari; Avila-Burgos, Leticia; Avokpaho, Euripide Frinel G. Arthur; Awasthi, Ashish; Ellingsen, Christian Lycke; Hailu, Alemayehu; Knudsen, Ann Kristin; Vollset, Stein Emil; Weiderpass, Elisabete (Peer reviewed; Journal article, 2017-09)
      Background: Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive ...
    • Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015 

      Forouzanfar, Mohammad H.; Afshin, Ashkan; Alexander, Lily T.; Aasvang, Gunn Marit; Bjertness, Espen; Htet, Aung Soe; Savic, Miloje; Vollset, Stein Emil; Norheim, Ole Frithjof; Weiderpass, Elisabete (Peer reviewed; Journal article, 2016-10)
      Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and ...
    • Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 

      Gakidou, Emmanuela; Afshin, Ashkan; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abdulle, Abdishakur M.; Abera, Semaw Ferede; Aboyans, Victor; Abu-Raddad, Laith J.; Abu-Rmeileh, Niveen M. E.; Abyu, Gebre Yitayih; Adedeji, Isaac Akinkunmi; Adetokunboh, Olatunji; Afarideh, Mohsen; Agrawal, Anurag; Agrawal, Sutapa; Kiadaliri, Aliasghar Ahmad; Ahmadieh, Hamid; Ahmed, Muktar Beshir; Aichour, Amani Nidhal; Aichour, Ibtihel; Aichour, Miloud Taki Eddine; Akinyemi, Rufus Olusola; Akseer, Nadia; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore; Alam, Tahiya; Alasfoor, Deena; Alene, Kefyalew Addis; Ali, Komal; Alizadeh-Navaei, Reza; Alkerwi, Ala'a; Alla, Francois; Allebeck, Peter; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Amare, Azmeraw T.; Amini, Erfan; Ammar, Walid; Amoako, Yaw Ampem; Ansari, Hossein; Anto, Josep M.; Antonio, Carl Abelardo T.; Anwari, Palwasha; Arian, Nicholas; Arnlov, Johan; Artaman, A.; Aryal, Krishna Kumar; Kisa, Adnan; Knudsen, Ann Kristin; Vollset, Stein Emil; Norheim, Ole Frithjof; Tollånes, Mette Christophersen; Weiderpass, Elisabete (Peer reviewed; Journal article, 2017-09)
      METHODS: We used the comparative risk assessment framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), ...