Browsing Department of Clinical Dentistry by Author "Mohamed Ahmed, Samih"
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Comparison of bone regenerative capacity of donor-matched human adipose–derived and bone marrow mesenchymal stem cells
Mohamed Ahmed, Samih; Yassin, Mohammed Ahmed; Elsebahy, Ahmad Rashad Saad Mohamed; Espedal, Heidi; Idris, Shaza Bushra M.; Finne-Wistrand, Anna; Vindenes, Hallvard; Mustafa, Kamal Babikeir Eln; Fristad, Inge (Journal article; Peer reviewed, 2020-11)Adipose-derived stem cells (ASC) have been used as an alternative to bone marrow mesenchymal stem cells (BMSC) for bone tissue engineering. However, the efficacy of ASC in bone regeneration in comparison with BMSC remains ... -
Efficacy of copolymer scaffolds delivering human demineralised dentine matrix for bone regeneration
Munir, Arooj; Døskeland, Anne; Avery, Steven J; Fuoco, Tiziana; Mohamed Ahmed, Samih; Lygre, Henning; Finne-Wistrand, Anna; Sloan, Alastair J; Waddington, Rachel J; Mustafa, Kamal Babikeir Eln; Suliman, Salwa (Journal article; Peer reviewed, 2019)Poly(L-lactide-co-ε-caprolactone) scaffolds were functionalised by 10 or 20 µg/mL of human demineralised dentine matrix. Release kinetics up to 21 days and their osteogenic potential on human bone marrow stromal cells after ... -
Engineering 3D degradable, pliable scaffolds toward adipose tissue regeneration; optimized printability, simulations and surface modification
Jain, Shubham; Yassin, Mohammed Ahmed; Fuoco, Tiziana; Liu, Hailong; Mohamed Ahmed, Samih; Mustafa, Kamal Babikeir Eln; Finne-Wistrand, Anna (Journal article; Peer reviewed, 2020)We present a solution to regenerate adipose tissue using degradable, soft, pliable 3D-printed scaffolds made of a medical-grade copolymer coated with polydopamine. The problem today is that while printing, the medical grade ... -
Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells
Suliman, Salwa; Ali, Hassan Mohamed Abdel-Raouf; Karlsen, Tommy Aleksander; Amiaud, Jérôme; Mohamed Ahmed, Samih; Layrolle, Pierre; Costea, Daniela Elena; Brinchmann, Jan E.; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2019-11-05)Therapeutic potential of human bone marrow stromal/stem cells (hBMSC) must be developed using well defined xenogenic-free conditions. hBMSC were isolated from healthy donors (n = 3) using different isolation and expansion ... -
Influence of platelet storage time on human platelet lysates and platelet lysate-expanded mesenchymal stromal cells for bone tissue engineering
Shanbhag, Siddharth; Mohamed Ahmed, Samih; Lunde, Turid Helen Felli; Suliman, Salwa; Bolstad, Anne Isine; Hervig, Tor; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2020)Background Human platelet lysate (HPL) is emerging as the preferred xeno-free supplement for the expansion of mesenchymal stromal cells (MSCs) for bone tissue engineering (BTE) applications. Due to a growing demand, the ...