Faculty of Medicine
Recent Submissions
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Primary health care delivery in a Sidama community undergoing demographic transition
(Doctoral thesis, 2022-12-14)Lav bruk av helsetjenester på den etiopiske landsbygd. Rundt halvparten av verdens befolkning har liten tilgang på livsviktige helsetjenester. Og, spesielt ilavinntektsland,er registreringen av sykelighets, fødsels og ... -
Births and deaths in Sidama in southern Ethiopia: findings from the 2018 Dale-Wonsho Health and Demographic Surveillance System (HDSS)
(Journal article; Peer reviewed, 2020)Background: Sidama is one of the most densely populated areas in Ethiopia. Information about the demographic characteristics is scarce, and most studies were census based on interviews. Earlier population studies from ... -
“Death audit is a fight” – provider perspectives on the ethics of the Maternal and Perinatal Death Surveillance and Response (MPDSR) system in Ethiopia
(Journal article; Peer reviewed, 2022)Background Maternal and neonatal health are regarded as important indicators of health in most countries. Death auditing through, for example, the Maternal and Perinatal Death Surveillance and Response (MPDSR) is viewed ... -
Brain plasticity after cognitive intervention in patients with mild cognitive impairment (MCI) evaluated by multimodal MR imaging in a randomized, controlled trial.
(Doctoral thesis, 2022-12-16)Hjerneplasitisitet undersøkt hos individer med mild kognitiv svikt etter PC-administrert arbeidsminnetrening, evaluert med multimodal MRI teknikk, en randomisert kontroll studie. Formål: Hovedmålet med studien var å ... -
"It's all in my head now" Readiness for return to sport after anterior cruciate ligament reconstruction
(Doctoral thesis, 2022-12-16)Bakgrunn: Det er utfordrende for klinikere å avgjøre om pasienter er klare for å returnere til idrett etter en korsbåndsoperasjon. Grunnen til dette er uklarhet knyttet til hvilke tester og kriterier som bør utgjøre ... -
Differences in lung function, bronchial hyperresponsiveness and respiratory health between elite athletes competing in different sports
(Journal article; Peer reviewed, 2022)The aim of this study was to examine lung function, bronchial hyperresponsiveness (BHR) and exercise-induced respiratory symptoms in elite athletes performing different sports. Norwegian national-team athletes (30 swimmers, ... -
Hot towels: The bedrock of Meibomian gland dysfunction treatment – A review
(Journal article; Peer reviewed, 2022)Background Meibomian gland dysfunction (MGD) reduces quality-of-life and hinders work productivity of millions of patients, with high direct and indirect societal costs. Thickened meibum obstructs the glands and disrupts ... -
Association of oral bacteria with oral hygiene habits and self-reported gingival bleeding
(Journal article; Peer reviewed, 2022)Aim To describe associations of gingival bacterial composition and diversity with self-reported gingival bleeding and oral hygiene habits in a Norwegian regional-based population. Materials and Methods We examined the ... -
VACCELERATE Volunteer Registry: A European study participant database to facilitate clinical trial enrolment
(Journal article; Peer reviewed, 2022)Introduction: The coronavirus disease 2019 (COVID-19) pandemic has evidenced the key role of vaccine design, obtention, production and administration to successfully fight against infectious diseases and to provide efficient ... -
Host Transcriptional Signatures Predict Etiology in Community-Acquired Pneumonia: Potential Antibiotic Stewardship Tools
(Journal article; Peer reviewed, 2022)Background: Current approaches for pathogen identification in community-acquired pneumonia (CAP) remain suboptimal, leaving most patients without a microbiological diagnosis. If better diagnostic tools were available for ... -
Shared genetic loci between depression and cardiometabolic traits
(Journal article; Peer reviewed, 2022-05-13)Epidemiological and clinical studies have found associations between depression and cardiovascular disease risk factors, and coronary artery disease patients with depression have worse prognosis. The genetic relationship ... -
Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1
(Journal article; Peer reviewed, 2022-06-02)Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. In different conditions, macrophage polarization can be induced by high-mobility group ... -
Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections
(Journal article; Peer reviewed, 2022)Background: Necrotising soft tissue infections (NSTIs) are rapidly progressing bacterial infections usually caused by either several pathogens in unison (polymicrobial infections) or Streptococcus pyogenes (mono-microbial ... -
Antiemetic treatment of hyperemesis gravidarum in 1,064 Norwegian women and the impact of European warning on metoclopramide: a retrospective cohort study 2002–2019
(Journal article; Peer reviewed, 2022-06-02)Background: Women suffering from severe nausea and vomiting during pregnancy, hyperemesis gravidarum, have poor quality of life and increased risk of potentially fatal maternal and fetal complications. There is increasing ... -
Radiation induced brain necrosis after proton therapy for head and neck cancer
(Doctoral thesis, 2022-12-09)Protonterapi gir reduksjon i normalvevsdoser sammenlignet med strålebehandling med fotoner, og det er antatt at dette vil resultere i en lavere forekomst av stråleinduserte seinskader. For å kompensere for en økt biologisk ... -
Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes
(Journal article; Peer reviewed, 2022-05-05)Persons with type 2 diabetes born in the regions of famine exposures have disproportionally elevated risk of vision-threatening proliferative diabetic retinopathy (PDR) in adulthood. However, the underlying mechanisms are ... -
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
(Journal article; Peer reviewed, 2022)We investigated genomic and transcriptomic changes in paired tumor samples of 29 in-house multiple myeloma (MM) patients and 28 patients from the MMRF CoMMpass study before and after treatment. A change in clonal composition ... -
Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function
(Journal article; Peer reviewed, 2022)Objective: Neonatal lupus erythematosus (NLE) may develop after transplacental transfer of maternal autoantibodies with cardiac manifestations (congenital heart block, CHB) including atrioventricular block, atrial and ... -
The value of histological examination in the diagnosis of tuberculous lymphadenitis in the era of rapid molecular diagnosis
(Journal article; Peer reviewed, 2022)Extrapulmonary tuberculosis often poses a diagnostic challenge. This study aimed to assess the value of histological examination in diagnosing tuberculous lymphadenitis (LNTB) when performed simultaneously with rapid ... -
Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes
(Journal article; Peer reviewed, 2022)Improved models of experimental diabetes are needed to develop cell therapies for diabetes. Here, we introduce the B6 RIP-DTR mouse, a model of experimental diabetes in fully immunocompetent animals. These inbred mice ...
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