• Worldwide trends in the underweight and obesity from 1990 to 2022: a pooled analysis of 3,633 population-representative studies with 222 million school-aged children, adolescents, and adults 

  Ostojic, Sergej; Phelps, Nowell H.; Singleton, Rosie K.; Zhou, Bin; Heap, Rachel; Mishra, Anu; Bennett, James B.; Paciorek, Christopher J; Lhoste, Victor P.F.; Carillo-Larco, Rodrigo; Stevens, Gretchen A.; Rodriguez-Martinez, Andrea; Bixby, Honor; Bentham, James; Danaei, Mariachiara; Rayner, Archie; Barradas-Pires, Ana; Cowan, Melanie J; Savin, Stefan; Riley, Leanne M; Aguilar-Salinas, Carlos; Aryal, Krishna Kumar; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Bere, Elling Tufte; Bergh, Ingunn Holden; Bjertness, Espen; Bjertness, Marius Bergsmark; Ekelund, Ulf; Gerdts, Eva; Grøholt, Else Karin; Haugsgjerd, Teresa Risan; Htet, Aung Soe; Igland, Jannicke; Janszky, Imre; Kjerpeseth, Lars Jøran; Kolle, Elin; Krokstad, Steinar; Madar, Ahmed Ali; Mathiesen, Ellisiv B.; Meisfjord, Jørgen Rajan; Meyer, Haakon Eduard; Sen, Abhijit; Sørgjerd, Elin Pettersen; Sparboe-Nilsen, Bente; Steene-Johannessen, Jostein; Steinsbekk, Silje; Sulo, Gerhard; Tell, Grethe S.; Torheim, Liv Elin; Vik, Frøydis Nordgård; Wichstrøm, Lars; Wilsgaard, Tom (Journal article; Peer reviewed, 2024)

  Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, ...

• Maternal seafood intake, dietary contaminant exposure, and risk of juvenile idiopathic arthritis: exploring gene-environment interactions 

  Dåstøl, Vilde Øverlien; Haftorn, Kristine Løkås; Rudsari, Hamid Khoshfekr; Jaholkowski, Piotr Pawel; Størdal, Ketil; Håberg, Siri Eldevik; Weinberg, Clarice R.; Rider, Lisa G.; Andreassen, Ole; Brantsæter, Anne Lise; Caspersen, Ida Henriette; Sanner, Helga (Journal article; Peer reviewed, 2024)

  Objectives: Juvenile idiopathic arthritis (JIA) originates from a complex interplay between genetic and environmental factors. We investigated the association between seafood intake and dietary contaminant exposure during ...

• Chemokine associations with blood cerebrospinal fluid (CSF) barrier permeability and delirium 

  Denver, Paul; Tortorelli, Lucas; Hov, Karen Roksund; Berg, Jens Petter; Giil, Lasse Melvær; Nazmi, Arshed; Lopez-Rodriguez, Ana; Healy, Dáire; Murray, Carol; Barry, Robyn; Watne, Leiv; Cunningham, Colm (Journal article; Peer reviewed, 2025)

  Delirium is a highly prevalent neuropsychiatric syndrome characterised by acute and fluctuating impairments in attention and cognition. Mechanisms driving delirium are poorly understood but it has been suggested that blood ...

• Streptokinase reduces Streptococcus dysgalactiae subsp. equisimilis biofilm formation 

  Tölken, Lea A.; Neufend, Janine V.; Oppegaard, Oddvar; Methling, Karen; Moll, Kirsten; Redanz, Sylvio; Katsburg, Miriam M D; Ali, Murtadha Q.; Shumba, Patience; Kreikemeyer, Bernd; Skrede, Steinar; Fulde, Marcus; Norrby-Teglund, Anna; Lalk, Michael; Kittang, Bård Reiakvam; Siemens, Nikolai (Journal article; Peer reviewed, 2024)

  Background Streptococcus dysgalactiae subspecies equisimilis (SDSE) is increasingly recognized as an emerging cause of invasive diseases including necrotizing soft tissue infections (NSTIs). In contrast to the closely ...

• Clinical characteristics, treatment, and outcomes for elderly patients in a dedicated Covid-19 ward at a primary health care facility in western Norway: a retrospective observational study 

  Kittang, Bård Reiakvam; Øien, Ane Tveiten; Engtrø, Einar; Skjellanger, Marian; Krüger, Kjell (Journal article; Peer reviewed, 2024)

  Background The coronavirus pandemic has hit the oldest and frailest individuals hard, particularly patients and residents in nursing homes. In March 2020, we established a Covid-19 ward at a nursing home in Bergen, ...

• Pregnancy outcomes as related to in utero exposure to air pollution and greenness: The Life-GAP Project 

  Sinsamala, Robin Mzati; Johannessen, Ane; Bertelsen, Randi Jacobsen; Accordini, Simone; Brandt, Jørgen; Frohn, Lise Marie; Geels, Camilla; Thorarinn, Gislason; Holm, Mathias; Janson, Christer; Markevych, Iana; Orru, Hans; Gomez Real, Francisco; Sigsgaard, Torben; Skulstad, Svein Magne; Svanes, Cecilie; Marcon, Alessandro (Journal article; Peer reviewed, 2024)

  Background: Lower birth weight and preterm birth may increase the risk of adverse health outcomes later in life. We examined whether maternal exposure to air pollution and greenness during pregnancy is associated with ...

• Diabetes and Osteoarthritis: Exploring the Interactions and Therapeutic Implications of Insulin, Metformin, and GLP-1-Based Interventions 

  Halabitska, Iryna; Babinets, Liliia; Oksenych, Valentyn; Kamyshnyi, Oleksandr (Journal article; Peer reviewed, 2024-07-23)

  Diabetes mellitus (DM) and osteoarthritis (OA) are prevalent chronic conditions with shared pathophysiological links, including inflammation and metabolic dysregulation. This study investigates the potential impact of ...

• Genomic insight into COVID-19 severity in MAFLD patients: a single-center prospective cohort study 

  Buchynskyi, Mykhailo; Oksenych, Valentyn; Kamyshna, Iryna; Budarna, Olena; Halabitska, Iryna; Petakh, Pavlo; Kamyshnyi, Oleksandr (Journal article; Peer reviewed, 2024-09-04)

  This study investigated the influence of single nucleotide polymorphisms (SNPs) in genes associated with the interferon pathway (IFNAR2 rs2236757), antiviral response (OAS1 rs10774671, OAS3 rs10735079), and viral entry ...

• Beta-Blockers of Different Generations: Features of Influence on the Disturbances of Myocardial Energy Metabolism in Doxorubicin-Induced Chronic Heart Failure in Rats 

  Belenichev, Igor; Goncharov, Olexiy; Bukhtiyarova, Nina; Kuchkovskyi, Oleh; Ryzhenko, Victor; Makyeyeva, Lyudmyla; Oksenych, Valentyn; Kamyshnyi, Oleksandr (Journal article; Peer reviewed, 2024-08-28)

  Beta-blockers are first-line drugs in the treatment of chronic heart failure (CHF). However, there is no consensus on the specific effects of the beta-blockers of the I-III generation on energy metabolism in CHF. The aim ...

• Development and Optimization of Nasal Composition of a Neuroprotective Agent for Use in Neonatology after Prenatal Hypoxia 

  Belenichev, Igor; Aliyeva, Olena; Burlaka, Bogdan; Burlaka, Kristina; Kuchkovskyi, Oleh; Savchenko, Dmytro; Oksenych, Valentyn; Kamyshnyi, Oleksandr (Journal article; Peer reviewed, 2024-07-26)

  The intranasal route of drug administration is characterized by high bioavailability and is considered promising for rapid delivery of drugs with systemic action to the central nervous system (CNS), bypassing the blood-brain ...

• Dysregulation of miR-223, miR-146a, and miR-193a Expression Profile in Acute and Chronic Phases of Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice 

  Gharibi, Saba; Moghimi, Bahram; Mahmoudi, Mohammad Bagher; Shahvazian, Ensieh; Yazd, Ehsan Farashahi; Yadegari, Maryam; Tahoori, Mohammad Taher; Yazdanpanah, Esmaeil; Haghmorad, Dariush; Oksenych, Valentyn (Journal article; Peer reviewed, 2024-09-06)

  Multiple sclerosis (MS) is a chronic autoimmune disease with an unknown etiology. The purpose of this research was to assess miR-223, miR-146a, and miR-193a in acute and chronic phases of experimental autoimmune encephalomyelitis ...

• Identification of Black Cumin (Nigella sativa) MicroRNAs by Next-Generation Sequencing and Their Implications in Secondary Metabolite Biosynthesis 

  Uriostegui-Pena, Andrea G.; Reyes-Calderón, Almendra; Gutiérrez-García, Claudia; Srivastava, Aashish; Sharma, Ashutosh; Paul, Sujay (Journal article; Peer reviewed, 2024-10-08)

  Secondary metabolites are bioactive compounds believed to contribute to the pharmacological properties of plants. MicroRNAs (miRNAs) are small non-coding RNA molecules involved in post-transcriptional regulation and are ...

• The association of premorbid conditions with 6-month mortality in acutely admitted ICU patients over 80 years 

  de Lange, Dylan W.; Soliman, Ivo W.; Leaver, Susannah; Boumendil, Ariane; Haas, Lenneke E. M.; Watson, Ximena; Boulanger, Carol; Szczeklik, Wojciech; Artigas, Antonio; Morandi, Alessandro; Andersen, Finn Husøy; Jung, Christian; Moreno, Rui; Walther, Sten M; Oeyen, Sandra; Schefold, Joerg C.; Cecconi, Maurizio; Marsh, Brian; Joannidis, Michael; Nalapko, Yuriy; Elhadi, Muhammed; Fjølner, Jesper; Guidet, Bertrand; Flaatten, Hans Kristian (Journal article; Peer reviewed, 2024)

  Background Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions ...

• Genetic association of antinuclear antibodies with HLA in JIA patients: a Swedish cohort study 

  Saleh, Raya; Sundberg, Erik; Olsson, Mia; Tengvall, Katarina; Alfredsson, Lars; Kockum, Ingrid; Padyukov, Leonid; Harris, Anna Helena Erlandsson (Journal article; Peer reviewed, 2024)

  Background Juvenile Idiopathic Arthritis (JIA) is a complex autoimmune disease and the most common chronic rheumatological disease affecting children under the age of 16. The etiology of JIA remains poorly understood, ...

• A Cross-Sectional Study of Peri-Implant Diseases in a Random Norwegian Population: Prevalence, Risk Indicators, and Clinical Validation of Patient-Reported Outcomes 

  Mauland, Erik Klepsland; Sørensen, Karoline; Aarbu, Naomi Østergren; Verket, Anders; Ellingsen, Stig Aanerød; Bull, Vibeke Hervik; Gaarden, Roya Torabi; Lie, Stein Atle; Bunæs, Dagmar Fosså (Journal article; Peer reviewed, 2024)

  Objectives The primary aim of this study was to investigate the prevalence of peri-implant diseases in a randomly selected Norwegian population. The secondary aims were to explore risk indicators for peri-implant diseases ...

• Association between heavy alcohol consumption and cryptogenic ischaemic stroke in young adults: A case-control study 

  Martinez-Majander, Nicolas; Kutal, Shakar; Ylikotila, Pauli; Yesilot, Nilufer; Tulkki, Lauri; Zedde, Marialuisa; Sarkanen, Tomi; Junttola, Ulla; Nordanstig, Annika; Fromm, Annette; Ryliskiene, Kristina; Licenik, Radim; Ferdinand, Phillip; Jatuzis, Dalius; Kõrv, Liisa; Kõrv, Janika; Pezzini, Alessandro; Tuohinen, Suvi; Sinisalo, Juha; Lehto, Mika; Gerdts, Eva; Ryödi, Essi; Autere, Jaana; Hedman, Marja; Fonseca, Ana Catarina; Waje-Andreassen, Ulrike; Von Sarnowski, Bettina; Redfors, Petra; Sairanen, Tiina; Tatlisumak, Turgut; Roine, Risto O; Huhtakangas, Juha; Numminen, Heikki; Jäkälä, Pekka; Putaala, Jukka (Journal article; Peer reviewed, 2024)

  Background The underlying risk factors for young-onset cryptogenic ischaemic stroke (CIS) remain unclear. This multicentre study aimed to explore the association between heavy alcohol consumption and CIS with subgroup ...

• Impaired Periodontitis-Induced Cytokine Production by Peripheral Blood Monocytes and Myeloid Dendritic Cells in Patients with Rheumatoid Arthritis: A Case–Control Study 

  Silva, Daniela S.; Laranjeira, Paula; Silva, Ana; Silva, Isabel; Kaminska, Marta; Mydel, Piotr Mateusz; de Vries, Charlotte; Lundberg, Karin; da Silva, José António P.; Baptista, Isabel P.; Paiva, Artur (Journal article; Peer reviewed, 2024)

  Background: Immune cells from rheumatoid arthritis (RA) patients display a reduced in vitro response to Porphyromonas gingivalis (P. gingivalis), which may have functional immune consequences. The aim of this study was to ...

• Heart failure with improved versus persistently reduced left ventricular ejection fraction: A comparison of the BIOSTAT-CHF (European) study with the ASIAN-HF registry 

  Cao, Thong Huy; Tay, Wan Ting; Jones, Donald J.L.; Cleland, John G.F.; Tromp, Jasper; Emmens, Johanna Elisabeth; Teng, Tiew-Hwa Katherine; Chandramouli, Chanchal; Slingsby, Oliver Charles; Anker, Stefan D.; dickstein, kenneth; Filippatos, Gerasimos; Lang, Chim C.; Metra, Marco; Ponikowski, Piotr; Samani, Nilesh J.; Van Veldhuisen, Dirk J.; Zannad, Faiez; Anand, Inder S.; Lam, Carolyn S.P.; Voors, Adriaan A.; Ng, Leong L. (Journal article; Peer reviewed, 2024)

  Aims We investigated the prevalence, clinical characteristics, and prognosis of patients with heart failure (HF) with improved ejection fraction (HFimpEF). Methods and results We used data from BIOSTAT-CHF including ...

• Overall survival in patients with endometrial cancer treated with dostarlimab plus carboplatin–paclitaxel in the randomized ENGOT-EN6/GOG-3031/RUBY trial 

  Powell, M.A.; Bjørge, Line; Willmott, L.; Novák, Z.; Black, D.; Gilbert, L.; Sharma, S.; Valabrega, G.; Landrum, L.M.; Gropp-Meier, M.; Stuckey, A.; Boere, I.; Gold, M.A.; Segev, Y.; Gill, S.E.; Gennigens, C.; Sebastianelli, A.; Shahin, M.S.; Pothuri, B.; Monk, B.J.; Buscema, J.; Coleman, R.L.; Slomovitz, B.M.; Ring, K.L.; Herzog, T.J.; Balas, M.M.; Grimshaw, M.; Stevens, S.; Lai, D.W.; McCourt, C.; Mirza, M.R. (Journal article; Peer reviewed, 2024)

  Background: Part 1 of the RUBY trial (NCT03981796) evaluated dostarlimab plus carboplatin–paclitaxel compared with placebo plus carboplatin–paclitaxel in patients with primary advanced or recurrent endometrial cancer (EC). ...

• A study of microRNAs as new prognostic biomarkers in anal cancer patients 

  Dahl, Olav; Myklebust, Mette Pernille (Journal article; Peer reviewed, 2024)

  Background: MicroRNA (MiR) influences the growth of cancer by regulation of mRNA for 50–60% of all genes. We present as per our knowledge the first global analysis of microRNA expression in anal cancer patients and their ...

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