Faculty of Medicine
Recent Submissions
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Novel tools to investigate Arc protein molecular function in synaptic plasticity
(Doctoral thesis, 2024-09-11)Synaptisk plastisitet er en korrelasjon for læring og hukommelse i det mammale hjernen, som produserer endringer på et synaptisk nivå i det nevrale nettverket, som kan være av kortvarig eller langvarig art. For langvarige ... -
Endovascular treatment in the elderly
(Doctoral thesis, 2024-09-13)Bakgrunn Nevrologiske lidelser utgjør en stor helsemessig utfordring og hjerneslag er globalt sett den nest hyppigste årsaken til død og den fremste årsaken til uførhet. Iskemisk hjerneslag behandles primært med medisinsk ... -
Mutation Spectrum in Liquid Versus Solid Biopsies From Patients With Advanced astroenteropancreatic Neuroendocrine Carcinoma
(Journal article; Peer reviewed, 2023)Purpose Gastroenteropancreatic neuroendocrine carcinomas (GEP-NEC) are rare and have a poor prognosis. Most GEP-NEC are diagnosed with metastatic disease, with only minor biopsies available for molecular diagnostics. We ... -
Outcomes of Patients With Graves Disease 25 Years After Initiating Antithyroid Drug Therapy
(Journal article; Peer reviewed, 2023)Context Graves disease (GD) is a leading cause of hyperthyroidism. Detailed investigations and predictors of long-term outcomes are missing. Objective This work aimed to investigate the outcomes in GD 25 years after ... -
Streptococcus dysgalactiae Bloodstream Infections, Norway, 1999-2021
(Journal article; Peer reviewed, 2023)Streptococcus dysgalactiae increasingly is recognized as a pathogen of concern for human health. However, longitudinal surveillance data describing temporal trends of S. dysgalactiae are scarce. We retrospectively identified ... -
Imaging tumor lactate is feasible for identifying intermediate-risk prostate cancer patients with postsurgical biochemical recurrence
(Journal article; Peer reviewed, 2023)While radical prostatectomy remains the mainstay of prostate cancer (PCa) treatment, 20 to 40% of patients develop postsurgical biochemical recurrence (BCR). A particularly challenging clinical cohort includes patients ... -
eRegMat – a digital registry for improved quality of antenatal care: a cluster-randomized trial in a rural area in Bangladesh
(Journal article; Peer reviewed, 2024)Introduction Longitudinal client tracking systems with digital health interventions are recommended for implementation in resource-limited settings but lack evidence of benefits, harms, and implementation. In the eRegMat ... -
Longitudinal Relationship Between Reduced Modic Change Edema and Disability and Pain in Patients With Chronic Low Back Pain
(Journal article; Peer reviewed, 2023)Study Design. Secondary analyses of a randomized trial [Antibiotics In Modic changes (MCs) study]. Objective. To assess whether or not reduced MC edema over time is related to reduced disability and pain in patients ... -
The impact of gingivitis reduction on lung function: a randomized trial under intensified oral hygiene
(Journal article; Peer reviewed, 2023)Background Periodontal disease and lung function impairment were found to be associated with low-grade systemic or local inflammation, and it might be that gingival/periodontal inflammation triggers lung function due ... -
Adult presentation of ornithine transcarbamylase deficiency: a possible cause of hyperammonemia after high-dose chemotherapy and stem cell transplantation
(Journal article; Peer reviewed, 2023)Hyperammonemia is a rare and often fatal complication following the conditioning therapy in autologous and allogeneic stem cell transplant recipients. It is characterized by anorexia, vomiting, lethargy and coma without ... -
Targeted client communication to improve timely antenatal care utilization : Assessment, development and evaluation
(Doctoral thesis, 2024-09-09)Bakgrunn Rettidige svangerskapskontroller reduserer sykelighet og dødelighet hos mor og nyfødt ved at gravide med økt risiko for svangerskapsrelaterte komplikasjoner kan identifiseres i tide, sikres adekvat behandling og ... -
Oral bacterial composition associated with lung function and lung inflammation in a community-based Norwegian population
(Journal article; Peer reviewed, 2023)Background The oral cavity is the gateway to the bacteria community in the lung. Disruption of the symbiotic balance of the oral microbiota has been associated with respiratory diseases. However, little is known about ... -
Excess non-COVID-19 mortality in Norway 2020–2022
(Journal article; Peer reviewed, 2024)Background Causes of death other than COVID-19 seem to contribute significantly to the excess mortality observed during the 2020–2022 pandemic. In this study, we explore changes in non-COVID-19 causes of death in Norway ... -
Early suppression policies protected pregnant women from COVID-19 in 2020: A population-based surveillance from the Nordic countries
(Journal article; Peer reviewed, 2024)Introduction The Coronavirus 2019 Disease (COVID-19) pandemic reached the Nordic countries in March 2020. Public health interventions to limit viral transmission varied across different countries both in timing and in ... -
Temporal trends in X-ray exposure during coronary angiography and percutaneous coronary intervention
(Journal article; Peer reviewed, 2020)Background. Percutaneous coronary intervention exposes patient and staff to ionizing radiation. Although staff only receive a small fraction of patient dose through scatter radiation, there are concerns about the potential ... -
Crowd Simulation with Deliberative-Reactive Agents
(Chapter, 2023)Crowd dynamics are emergent processes caused by local pedestrian interactions. In this work, we describe a decentralized crowd simulation model based on deliberative-reactive agents. The model simulates fire evacuation ... -
Roles of extracellular vesicles in glioblastoma: foes, friends and informers
(Journal article; Peer reviewed, 2023)Glioblastoma (GB) tumors are one of the most insidious cancers which take over the brain and defy therapy. Over time and in response to treatment the tumor and the brain cells in the tumor microenvironment (TME) undergo ... -
Linking resting state metabolite concentrations in the dorsal anterior cingulate cortex to response inhibition in OCD, a combined fMRI-MRS study
(Journal article; Peer reviewed, 2023)Introduction Obsessive-compulsive disorder (OCD) has been associated with abnormal brain activation in regions related to response inhibition, such as the dorsal anterior cingulate cortex (dACC), as well as dysregulation ... -
Conformational analysis of membrane-proximal segments of GDAP1 in a lipidic environment using synchrotron radiation suggests a mode of assembly at the mitochondrial outer membrane
(Journal article; Peer reviewed, 2023)The mitochondrial outer membrane creates a diffusion barrier between the cytosol and the mitochondrial intermembrane space, allowing the exchange of metabolic products, important for efficient mitochondrial function in ... -
Forward genetics and functional analysis highlight Itga11 as a modulator of murine psoriasiform dermatitis
(Journal article; Peer reviewed, 2023)Psoriasis is a chronic inflammatory skin condition. Repeated epicutaneous application of Aldara® (imiquimod) cream results in psoriasiform dermatitis in mice. The Aldara®-induced psoriasiform dermatitis (AIPD) mouse model ...
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