Faculty of Medicine
Nye registreringer
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Challenges and Prospects for Designer T and NK Cells in Glioblastoma Immunotherapy
(Journal article; Peer reviewed, 2021)Glioblastoma (GBM) is the most prevalent, aggressive primary brain tumour with a dismal prognosis. Treatment at diagnosis has limited efficacy and there is no standardised treatment at recurrence. New, personalised treatment ... -
Circadian typology and implications for adolescent sleep health. Results from a large, cross-sectional, school-based study
(Journal article; Peer reviewed, 2021)Study objectives To investigate circadian typology in a large, representative sample of Norwegian adolescents, and its implications for sleep health. Methods The sample included 3920 1st year high school students aged ... -
The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1
(Journal article; Peer reviewed, 2021)Increasing evidence suggests that neurodevelopmental alterations might contribute to increase the susceptibility to develop neurodegenerative diseases. We investigate the occurrence of developmental abnormalities in ... -
Increased risk of hospitalisation and intensive care admission associated with reported cases of SARS-CoV-2 variants B.1.1.7 and B.1.351 in Norway, December 2020-May 2021
(Journal article; Peer reviewed, 2021)Introduction Since their emergence, SARS-CoV-2 variants of concern (VOC) B.1.1.7 and B.1.351 have spread worldwide. We estimated the risk of hospitalisation and admission to an intensive care unit (ICU) for infections ... -
The Inverse Association of Body Mass Index with Lung Cancer: Exploring Residual Confounding, Metabolic Aberrations and Within-Person Variability in Smoking
(Journal article; Peer reviewed, 2021)Background: The inverse observational association between body mass index (BMI) and lung cancer risk remains unclear. We assessed whether the association is explained by metabolic aberrations, residual confounding, and ... -
Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison's Disease
(Journal article; Peer reviewed, 2021)Background No reliable biomarkers exist to guide glucocorticoid (GC) replacement treatment in autoimmune Addison’s disease (AAD), leading to overtreatment with alarming and persistent side effects or undertreatment, which ... -
Sex-Specific Limitations in Physical Health in Primary Adrenal Insufficiency
(Journal article; Peer reviewed, 2021)Background: Patients with primary adrenal insufficiency (PAI) suffer reduced quality of life (QoL), but comparisons with large-scale normative data are scarce. The clinical characteristics associated with reduced QoL are ... -
Sleep and physical activity from before conception to the end of pregnancy in healthy women: a longitudinal actigraphy study
(Journal article; Peer reviewed, 2021)Background Sleep and physical activity changes are common in pregnancy, but longitudinal data starting before conception are scarce. Our aim was to determine the changes of the daily total sleep time (TST) and physical ... -
Health and Healthcare Access and Utilization Among Syrian Refugees Migrating to Norway : A Longitudinal Study
(Doctoral thesis, 2022-01-26)Background: An unprecedented number of people are on the move today and the health of refugees has become a vital global public health concern. During the migration process, refugees move from one environment to another ... -
In vitro kvalitet og hemostatisk funksjon i kaldlagret CPDA-1 fullblod etter gjentatte temperatursvingninger til 28 °C
(Master thesis, 2021-11-15)Bakgrunn: Blodprodukter blir ofte utsatt for romtemperatur eller høyere i lengre perioder enn tillatt av retningslinjer. Jeg undersøkte om dette førte til målbar effekt på mye brukte kvalitetsparametere og viskoelastisk ... -
Etiske utfordringer i sykehjem under Covid-19 pandemien -pleiepersonells erfaringer
(Master thesis, 2021-11-15)Covid-19 pandemien fikk store konsekvenser for pasienter og ansatte i sykehjem. Hensikten med denne studien er å etablere kunnskap om de etiske utfordringene ansatte i sykehjem erfarte under Covid-19 pandemien i 2020/21 ... -
Role of Adipocyte SLC7A10 and Amino Acid Metabolism in Obesity and Insulin Resistance
(Doctoral thesis, 2020-12-18)Obesity is a rising global concern, associated with increased risk of developing metabolic syndrome, insulin resistance and type 2 diabetes. Chronic availability of excess nutrients may promote adipocyte dysfunction, ... -
Use of quantitative pathology to improve grading and predict prognosis in tumours of the gastrointestinal tract
(Doctoral thesis, 2022-01-14)Cancer represents a formidable health burden and was the second leading cause of death globally in 2018. In Norway, almost 35000 new cancer cases were reported in 2019. For colon cancer, the incidence and mortality rates ... -
Work and health in the coir industry in Sri Lanka: a descriptive study with a specific focus on risk factors for injuries and incidence of injuries at these workplaces
(Master thesis, 2021-11-23)Abstract Introduction The coir industry processes fibres from coconuts. This industry plays an important role in sustaining the livelihood of a large number of people in Sri Lanka. Coir-related exports account for 6% of ... -
Phosphatidylserine receptors enhance SARS-CoV-2 infection
(Journal article; Peer reviewed, 2021)Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through virion-associated PS binding that is termed apoptotic mimicry. Here we show that this broadly shared uptake mechanism is utilized by ... -
Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry
(Journal article; Peer reviewed, 2021)H-1 parvovirus (H-1PV) is a promising anticancer therapy. However, in-depth understanding of its life cycle, including the host cell factors needed for infectivity and oncolysis, is lacking. This understanding may guide ... -
Current status of thulium fibre laser lithotripsy: an up-to-date review
(Journal article; Peer reviewed, 2021)Objective To perform an up-to-date review to scope the current status of the thulium fibre laser (TFL) in the setting of stone lithotripsy and provide a guide for the clinical urologist. Methods A review of world ... -
How Does Implant Survivorship Vary with Different Corail Femoral Stem Variants? Results of 51,212 Cases with Up to 30 Years Of Follow-up from the Norwegian Arthroplasty Register
(Journal article; Peer reviewed, 2021)Background: The Corail® cementless stem (DePuy Synthes) has been used in Norway since 1987 and is one of the most frequently used stems in THA worldwide. Although the published survival results of the standard Corail stem ... -
The effect of Zhang’s guideline versus the WHO partograph on childbirth experience measured by the Childbirth Experience Questionnaire in the Labor Progression Study (LaPS): A cluster randomized trial
(Journal article; Peer reviewed, 2021)Introduction Childbirth experience is an increasingly recognized and important measure of quality of obstetric care. Previous research has shown that it can be affected by intrapartum care and how labor is followed. A ... -
Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs
(Journal article; Peer reviewed, 2021-11-30)Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation and bone regeneration capacity of mesenchymal stromal cells (MSC). Gingiva-derived progenitor cells (GPC) represent a less invasive alternative ...
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