• EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection 

  Lee, Yunsung; Riskedal, Espen; Kalleberg, Karl Trygve; Istre, Mette Stausland; Lind, Andreas; Lund-Johansen, Fridtjof; Reiakvam, Olaug Marie; Søraas, Arne Vasli; Harris, Jennifer Ruth; Dahl, John Arne; Lund Hadley, Cathrine; Jugessur, Astanand (Journal article; Peer reviewed, 2022)

  Although substantial progress has been made in managing COVID-19, it is still difficult to predict a patient’s prognosis. We explored the epigenetic signatures of COVID-19 in peripheral blood using data from an ongoing ...

• Multimodal multi-center analysis of electroconvulsive therapy effects in depression: Brainwide gray matter increase without functional changes 

  van de Mortel, L.A.; Bruin, W.B.; Thomas, R.M.; Abbott, C.; Argyelan, M.; van Eijndhoven, P.; Mulders, P.; Narr, K.L.; Tendolkar, I.; Verdijk, J.P.A.J.; van Waarde, J.A.; Bartsch, Hauke; Oltedal, Leif; van Wingen, G.A. (Journal article; Peer reviewed, 2022)

  Background: Electroconvulsive therapy (ECT) is an effective treatment for severe depression and induces gray matter (GM) increases in the brain. Small-scale studies suggest that ECT also leads to changes in brain functioning, ...

• Infant iodine status and associations with maternal iodine nutrition, breastfeeding status and thyroid function 

  Næss, Synnøve; Aakre, Inger; Strand, Tor Arne; Dahl, Lisbeth; Kjellevold, Marian; Stokland, Ann-Elin Meling; Nedrebø, Bjørn Gunnar; Markhus, Maria Wik (Journal article; Peer reviewed, 2022)

  Adequate iodine nutrition during infancy is required for normal thyroid function and, subsequently, brain development. However, data on infant iodine status in the first year of life are scarce. This study aimed to describe ...

• Kidney biopsy diagnosis in childhood in the Norwegian Kidney Biopsy Registry and the long-term risk of kidney replacement therapy: a 25-year follow-up 

  Gjerstad, Ann Christin; Skrunes, Rannveig; Tøndel, Camilla; Åsberg, Anders; Leh, Sabine; Klingenberg, Claus Andreas; Døllner, Henrik; Hammarström, Clara Louise; Bjerre, Anna Kristina (Journal article; Peer reviewed, 2022)

  Background: There is scarce information on biopsy-verified kidney disease in childhood and its progression to chronic kidney disease stage 5 (CKD 5). This study aims to review biopsy findings in children, and to investigate ...

• More Than Fish—Framing Aquatic Animals within Sustainable Food Systems 

  Pounds, Alexandra; Kaminski, Alexander M.; Budhathoki, Mausam; Gudbrandsen, Oddrun Anita; Kok, Björn; Horn, Stephanie; Malcorps, Wesley; Mamun, Abdullah-Al; McGoohan, Amy; Newton, Richard; Ozretich, Reed; Little, David C. (Journal article; Peer reviewed, 2022)

  Aquatic animals are diverse in terms of species, but also in terms of production systems, the people involved, and the benefits achieved. In this concept piece, we draw on literature to outline how the diversity of aquatic ...

• Quantitative proteome profiling reveals molecular hallmarks of egg quality in Atlantic halibut: impairments of transcription and protein folding impede protein and energy homeostasis during early development 

  Yilmaz, Ozlem; Mangor-Jensen, Anders; Harboe, Torstein; Drønen, Margareth Møgster; Mangor-Jensen, Ragnfrid; Mjaavatten, Olav; Birkeland, Even; Spriet, Endy; Sandven, Linda; Furmanek, Tomasz; Berven, Frode Steingrimsen; Wargelius, Anna; Norberg, Birgitta (Journal article; Peer reviewed, 2022)

  Background Tandem mass tag spectrometry (TMT labeling-LC-MS/MS) was utilized to examine the global proteomes of Atlantic halibut eggs at the 1-cell-stage post fertilization. Comparisons were made between eggs judged to ...

• Agreement of clinical assessment of burn size and burn depth between referring hospitals and burn centres: A systematic review 

  Brekke, Ragnvald Ljones; Almeland, Stian Kreken; Hufthammer, Karl Ove; Hansson, Emma (Journal article; Peer reviewed, 2022)

  Background: The quality of burn care is highly dependent on the initial assessment and care. The aim of this systematic review was to investigate the agreement of clinical assessment of burn depth and %TBSA between the ...

• Impact of previous disease-modifying treatment on safety and efficacy in patients with MS treated with AHSCT 

  Stokke, Silje Agnethe; Burman, Joachim; Lehmann, Anne Kristine; Tolf, Andreas; Zjukovskaja, Christina; Melve, Guro Kristin; Bø, Lars; Torkildsen, Øivind (Journal article; Peer reviewed, 2022)

  Background Autologous haematopoietic stem cell transplantation (AHSCT) is a highly effective treatment for multiple sclerosis (MS). The impact of previous long-lasting disease-modifying treatments (DMT) for safety and ...

• Is intracranial volume a risk factor for IDH-mutant low-grade glioma? A case-control study 

  Sagberg, Lisa Millgård; Fyllingen, Even Hovig; Hansen, Tor Ivar; Strand, Per Sveino; Håvik, Aril Løge; Sundstrøm, Terje; Corell, Alba; Jakola, Asgeir Store; Salvesen, Øyvind; Solheim, Ole (Journal article; Peer reviewed, 2022)

  Purpose Risk of cancer has been associated with body or organ size in several studies. We sought to investigate the relationship between intracranial volume (ICV) (as a proxy for lifetime maximum brain size) and risk of ...

• Multimarker profiling identifies protective and harmful immune processes in heart failure: Findings from BIOSTAT-CHF 

  Markousis-Mavrogenis, George; Tromp, Jasper; Ouwerkerk, Wouter; Ferreira, João Pedro; Anker, Stefan D; Cleland, John G; Dickstein, Kenneth; Filippatos, Gerasimos; Lang, Chim C; Metra, Marco; Samani, Nilesh J; De Boer, Rudolf A; Van Veldhuisen, Dirk J; Voors, Adriaan A; Van Der Meer, Peter (Journal article; Peer reviewed, 2022)

  Aims The exploration of novel immunomodulatory interventions to improve outcome in heart failure (HF) is hampered by the complexity/redundancies of inflammatory pathways, which remain poorly understood. We thus aimed to ...

• Thrombectomy in large vessel occlusion stroke—Does age matter? 

  Rezai Kallaj, Mehdi; Dalen, Ingvild; Advani, Rajiv; Fjetland, Lars; Kurz, Kathinka Dæhli; Sandve, Knut Olav Lende; Kurz, Friedrich Martin Wilhelm (Journal article; Peer reviewed, 2022)

  Objectives Endovascular treatment (EVT) is the gold standard treatment for emergent large vessel occlusion (LVO). The benefit of EVT for emergent LVO in elderly patients (>80 years old) is still debated as they have been ...

• Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells 

  Khatri, Bhuwan; Tessneer, Kandice L.; Rasmussen, Astrid; Aghakhanian, Farhang; Reksten, Tove Ragna; Adler, Adam; Alevizos, Ilias; Anaya, Juan-Manuel; Aqrawi, Lara A.; Baecklund, Eva; Brun, Johan Gorgas; Bucher, Sara Magnusson; Eloranta, Maija-Leena; Engelke, Fiona; Forsblad-d’Elia, Helena; Glenn, Stuart B.; Hammenfors, Daniel; Imgenberg-Kreuz, Juliana; Jensen, Janicke Liaaen; Johnsen, Svein Joar Auglæn; Jonsson, Malin Viktoria; Kvarnström, Marika; Kelly, Jennifer A.; Li, He; Mandl, Thomas; Martín, Javier; Nocturne, Gaétane; Norheim, Katrine Brække; Palm, Øyvind; Skarstein, Kathrine; Stolarczyk, Anna M.; Taylor, Kimberly E.; Teruel, Maria; Theander, Elke; Venuturupalli, Swamy; Wallace, Daniel J.; Grundahl, Kiely M.; Hefner, Kimberly S.; Radfar, Lida; Lewis, David M.; Stone, Donald U.; Kaufman, C. Erick; Brennan, Michael T.; Guthridge, Joel M.; James, Judith A.; Scofield, R. Hal; Gaffney, Patrick M.; Criswell, Lindsey A.; Jonsson, Roland; Eriksson, Per; Bowman, Simon J.; Omdal, Roald; Rönnblom, Lars; Warner, Blake; Rischmueller, Maureen; Witte, Torsten; Farris, A. Darise; Mariette, Xavier; Alarcon-Riquelme, Marta E.; Shiboski, Caroline H.; Herlenius, Marie Elisabeth Wahren; Ng, Wan-Fai; Sivils, Kathy L.; Adrianto, Indra; Nordmark, Gunnel; Lessard, Christopher J. (Journal article; Peer reviewed, 2022)

  Sjögren’s disease is a complex autoimmune disease with twelve established susceptibility loci. This genome-wide association study (GWAS) identifies ten novel genome-wide significant (GWS) regions in Sjögren’s cases of ...

• Trauma team training in Norwegian hospitals: an observational study 

  Bredin, Ida Celine; Gaup, Hedi Marina Joks; Brattebø, Guttorm; Wisborg, Torben (Journal article; Peer reviewed, 2022)

  Background Traumatic injuries are a leading cause of deaths in Norway, especially among younger males. Trauma-related mortality can be reduced by structural measures, such as organization of a trauma system. Many hospitals ...

• Preoperative pelvic MRI and 2-[18F]FDG PET/CT for lymph node staging and prognostication in endometrial cancer—time to revisit current imaging guidelines? 

  Fasmer, Kristine Eldevik; Gulati, Ankush; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Lura, Njål Gjærde; Salvesen, Øyvind; Forsse, David Erik; Trovik, Jone; Pijnenborg, Johanna M. A.; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022)

  Objective This study presents the diagnostic performance of four different preoperative imaging workups (IWs) for prediction of lymph node metastases (LNMs) in endometrial cancer (EC): pelvic MRI alone (IW1), MRI and ...

• Medication Prescription, Common Side-effects, and Nutritional Status are Associated in Patients With Chronic Kidney Disease 

  Dahl, Helene; Sandblost, Silje Regine Thue; Welland, Natasha Lervaag; Sandnes, Kristina; Sekse, Ingegjerd; Sæle, Kristin; Marti, Hans Peter; Holst, Lone; Dierkes, Jutta (Journal article; Peer reviewed, 2022)

  Objective Chronic kidney disease (CKD) is associated with metabolic, nutritional, and extra-renal changes, as well as a high rate of comorbidities, which necessitates the prescription of numerous medications. Patients ...

• Psykososiale aspekter ved prediktiv genetisk testing for kardiomyopati – Hva vet vi i dag? 

  Hauan, Sindre Haukefer (Master thesis, 2022-06-23)

  Bakgrunn: De siste årene har det vært en økning i genetiske utredninger av hjertesykdom, noe som gjør det spesielt relevant å oppsummere kunnskapen om hvordan personer påvirkes av dette. Denne kunnskapen kan bidra med å ...

• Garbage codes in the Norwegian Cause of Death Registry 1996-2019 

  Ellingsen, Christian Lycke; Alfsen, Glenny Cecilie; Ebbing, Marta; Pedersen, Anne Gro; Sulo, Gerhard; Vollset, Stein Emil; Braut, Geir Sverre (Journal article; Peer reviewed, 2022)

  Background Reliable statistics on the underlying cause of death are essential for monitoring the health in a population. When there is insufficient information to identify the true underlying cause of death, the death ...

• Impact of Total Hip Replacements on the Incidence of Hip Fractures in Norway During 1999–2019. A Norwegian Epidemiologic Osteoporosis Studies (NOREPOS) Study 

  Kjeldgaard, Helena Kames; Meyer, Haakon Eduard; O’Flaherty, Martin; Apalset, Ellen Margrete; Dahl, Cecilie; Emaus, Nina; Fenstad, Anne Marie; Furnes, Ove Nord; Gjertsen, Jan-Erik; Hoff, Mari; Schei, Berit; Søgaard, Anne-Johanne; Tell, Grethe Seppola; Holvik, Kristin (Journal article; Peer reviewed, 2022)

  The knowledge about why hip fracture rates in Norway have declined is sparse. Concurrent with decreasing hip fracture rates, the rates of total hip replacements (THRs) have increased. We wanted to investigate if hip fracture ...

• Neurological disorders in Northern Tanzania: A 6-year prospective hospital-based case series 

  Howlett, William Patrick; Urasa, Sarah J.; Maro, Venance P.; Walker, Richard W.; Kilonzo, Kajiru G.; Howlett, Patrick J.; Dekker, Marieke C. J. (Journal article; Peer reviewed, 2022)

  Background: The burden of neurological disorders is large and altered by the HIV epidemic. Objectives: We describe the pattern of neurological disorders and their association with HIV infection in adult patients attending ...

• Shared etiology of type 1 diabetes and Hashimoto’s thyroiditis: a population-based twin study 

  Skov, Jakob; Kuja-Halkola, Ralf; Magnusson, Patrik K.E.; Gudbjörnsdottir, Soffia; Kämpe, Olle; Bensing, Sophie (Journal article; Peer reviewed, 2022)

  Objective Type 1 diabetes and Hashimoto’s thyroiditis frequently cluster in individuals and in families, indicating shared origins. The objective of this study was to investigate familial co-aggregation of these diseases ...

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