Faculty of Medicine
Recent Submissions
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The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers' Disease
(Journal article; Peer reviewed, 2024)Alpers' syndrome is an early-onset neurodegenerative disorder usually caused by biallelic pathogenic variants in the gene encoding the catalytic subunit of polymerase-gamma (POLG), which is essential for mitochondrial DNA ... -
Population-based tuberculosis screening : Prevalence, incidence and cluster analysis in southern Ethiopia
(Doctoral thesis, 2024-10-25)Bakgrunn: Detyyt har vært mange internasjonale initiativer for å stoppe tuberkuloseepidemien, og både tuberkulosedødelighet og insidensrater faller globalt. Likevel er sykdommen en betydelig utfordring for befolkninger og ... -
Maternal mortality in Sidama Region, southern Ethiopia : Results from surveys on mortality and the coverage of available interventions
(Doctoral thesis, 2024-10-22)Summary Background: Etiopia er et lavinntektsland hvor mødredødsfall er et stort samfunnshelse problem. I 2020 døde 10,000 mødre i Etiopia og dette representerte 3.6% av den globale byrden. Etiopia mangler et register ... -
Structure-based design of 1-deoxy-D-xylulose 5-phosphate reductoisomerase ligands
(Doctoral thesis, 2024-08-29)The widespread use of antibiotics has undoubtedly saved countless lives over the last century. However, their indiscriminate use has contributed to the emergence of antimicrobial resistance (AMR), posing a significant ... -
A scoping review on the associations between early childhood caries and sustainable cities and communities using the sustainable development goal 11 framework
(Journal article; Peer reviewed, 2024)Background: Early childhood caries (ECC) is a multifactorial disease in which environmental factors could play a role. The purpose of this scoping review was to map the published literature that assessed the association ... -
Association between early childhood caries and parental education and the link to the sustainable development goal 4: a scoping review
(Journal article; Peer reviewed, 2024-05-02)Background: The goal of the United Nations Sustainable Development Goal (SDG) 4 is to ensure inclusive and equitable quality education and promote lifelong learning opportunities for all. The aim of this scoping review was ... -
Early childhood caries, climate change and the sustainable development goal 13: a scoping review
(Journal article; Peer reviewed, 2024-05-03)Background: Sustainable development goal 13 centres on calls for urgent action to combat climate change and its impacts. The aim of this scoping review was to map the published literature for existing evidence on the ... -
Health complaints before and at one and five years after removal of dental amalgam restorations - data from a prospective cohort study in Norway
(Journal article; Peer reviewed, 2024)Objective: Health complaints attributed to dental amalgam fillings comprise both intraoral and general health complaints. There are data suggesting that patients with medically unexplained physical symptoms (MUPS) attributed ... -
Previous cartilage surgery is associated with inferior patient-reported outcomes after knee arthroplasty
(Journal article; Peer reviewed, 2024)Purpose: The hypothesis of the present study assumed that a history of focal cartilage lesions would not affect Knee Injury and Osteoarthritis Outcome scores (KOOSs) following knee arthroplasty compared to a matched national ... -
Biotin: a scoping review for Nordic Nutrition Recommendations 2023
(Journal article; Peer reviewed, 2024)Biotin is a water-soluble B-vitamin with key roles in metabolism and are found in most foods at low concentrations. Symptomatic biotin deficiency is rare, and few studies have investigated biotin requirements in relation ... -
Extracellular Vesicles as Next-Generation Diagnostics and Advanced Therapy Medicinal Products
(Journal article; Peer reviewed, 2024-06-13)Extracellular vesicles (EVs) hold great promise for clinical application as new diagnostic and therapeutic modalities. This paper describes major GMP-based upstream and downstream manufacturing processes for EV large-scale ... -
Feasibility of a physical activity intervention for children and adolescents with anxiety and depression
(Journal article; Peer reviewed, 2024-03-05)Background: Physical activity is identified as a key modifiable factor towards good short- and long-term mental health and has shown positive effects on anxiety and depression in children and adolescents. However, physical ... -
Sleep characteristics and changes in sleep patterns among infants in Bhaktapur, Nepal
(Journal article; Peer reviewed, 2024)Objective Sleep undergoes major changes during the first year of life, but the characteristics of sleep among infants in low and middle-income countries are not well documented. This study describes sleep characteristics ... -
Legumes and pulses - a scoping review for Nordic Nutrition Recommendations 2023
(Journal article; Peer reviewed, 2024)Consumption of legumes and pulses is associated with various health outcomes. Therefore, when updating the Nordic Nutrition Recommendations (NNR), summarizing the best available evidence on key health outcomes regarded as ... -
Social withdrawal behaviour in Nepalese infants and the relationship with future neurodevelopment; a longitudinal cohort study
(Journal article; Peer reviewed, 2024)Background Social withdrawal in infants may be a signal of distress and a precursor for non-optimal development. Objective To examine the relationship between infant social withdrawal and neurodevelopment up to 4 years in ... -
The impact on primary care of a large waterborne campylobacter outbreak in Norway: a controlled observational study
(Journal article; Peer reviewed, 2024)Objective: Document the impact of an outbreak of gastroenteritis on local primary health careservices, compared to a control period. Design: controlled observational study with data from the outbreak and a control period. ... -
Hvor søker fastleger hjelp ved egen sykdom?
(Journal article; Peer reviewed, 2024)Bakgrunn Leger har generelt god helse, men unnlater ofte å søke hjelp når de blir syke. Egenbehandling er utbredt. Dette kan være en uheldig og risikabel praksis. Materiale og metode Dette er en registerstudie hvor fastlegers ... -
Socioeconomic differences in use of antiseizure medication in pregnancies with maternal epilepsy: A population-based study from Nordic universal health care systems
(Journal article; Peer reviewed, 2024)Objective Research points to disparities in disease burden and access to medical care in epilepsy. We studied the association between socioeconomic status (SES) and antiseizure medication (ASM) use in pregnancies with ... -
Behavioral Inhibition and Social Anxiety Disorder as Predictors of Long-Term Outcomes of Cognitive Behavioral Therapy for Youth Anxiety Disorders
(Journal article; Peer reviewed, 2024)The temperamental trait behavioral inhibition (BI) is related to the development and maintenance of anxiety, particularly much so to social anxiety disorder. We investigated if BI and social anxiety disorder predicted ... -
Areas of consensus on unwarranted and warranted transfers between nursing homes and emergency care facilities in Norway: a Delphi study
(Journal article; Peer reviewed, 2024)Background Transferring residents from nursing homes (NHs) to emergency care facilities (ECFs) is often questioned as many are terminally ill and have access to onsite care. While some NH to ECF transfers have merit, ...
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