Faculty of Medicine
Recent Submissions
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Diagnosis of extrapulmonary tuberculosis using the MPT64 antigen detection test in a high-income low tuberculosis prevalence setting
(Journal article; Peer reviewed, 2020)Background Extrapulmonary tuberculosis (EPTB) poses diagnostic challenges due to the paucibacillary nature of the disease. The immunochemistry-based MPT64 antigen detection test (MPT64 test) has shown promising results ... -
Possible role of intestinal stem cells in the pathophysiology of irritable bowel syndrome
(Journal article; Peer reviewed, 2020)The pathophysiology of irritable bowel syndrome (IBS) is not completely understood. However, several factors are known to play a role in pathophysiology of IBS such as genetics, diet, gut microbiota, gut endocrine cells, ... -
Accumulation of Globotriaosylceramide in Podocytes in Fabry Nephropathy Is Associated with Progressive Podocyte Loss
(Journal article; Peer reviewed, 2020)Background In males with classic Fabry disease, the processes leading to the frequent outcome of ESKD are poorly understood. Defects in the gene encoding α-galactosidase A lead to accumulation of globotriaosylceramide (GL3) ... -
Placental inflammation by HMGB1 activation of TLR4 at the syncytium
(Journal article; Peer reviewed, 2018)Introduction Normal pregnancy is characterized by an elevated inflammatory state involving the placenta. The placental inflammation is further increased in preeclampsia, resulting in release of harmful danger signals to ... -
Vitamin D Status and Its Determinants in a Paediatric Population in Norway
(Journal article; Peer reviewed, 2020)Recommendations for sufficient vitamin D intake in children were recently revised in Norway. However, optimal levels of vitamin D are still debated and knowledge on supplementation and vitamin D levels in healthy children ... -
Nurse-patient interaction and self-transcendence: assets for a meaningful life in nursing home residents?
(Journal article; Peer reviewed, 2020)Background Due to the shift to an older population worldwide and an increased need for 24-h care, finding new and alternative approaches to increase wellbeing among nursing home (NH) residents is highly warranted. To guide ... -
Effects of replacing PSA with Stockholm3 for diagnosis of clinically significant prostate cancer in a healthcare system – the Stavanger experience
(Journal article; Peer reviewed, 2020)Objective To describe early experience of replacing PSA with Stockholm3 for detection of prostate cancer in primary care. Design and methods Longitudinal observations, comparing outcome measures before and after the ... -
The Cognitive Profile of Mild Cognitive Impairment Due to Dementia With Lewy Bodies—An Updated Review
(Journal article; Peer reviewed, 2020)Objective: Dementia with Lewy Bodies (DLB) is the second most common type of neurodegenerative dementia. Yet, the domain-specific cognitive impairment of the mild cognitive impairment (MCI) phase of this disease (DLB-MCI) ... -
Effects of Long-Term Physical Activity and Diet on Skin Glycation and Achilles Tendon Structure
(Journal article; Peer reviewed, 2019)Advanced glycation end-products (AGEs) accumulate with aging and have been associated with tissue modifications and metabolic disease. Regular exercise has several health benefits, and the purpose of this study was to ... -
Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases
(Journal article; Peer reviewed, 2020-03)Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report ... -
Evaluation of a low-dose protocol for cone beam computed tomography of the temporomandibular joint
(Journal article; Peer reviewed, 2020)Objective: Evaluation of cone beam CT (CBCT) examination with a low-dose scanning protocol for assessment of the temporomandibular joint (TMJ). Methods: 34 adult patients referred for CBCT imaging of the TMJ underwent ... -
Variability in functional outcome and treatment practices by treatment center after out-of-hospital cardiac arrest: analysis of International Cardiac Arrest Registry
(Journal article; Peer reviewed, 2019)Purpose Functional outcomes vary between centers after out-of-hospital cardiac arrest (OHCA) and are partially explained by pre-existing health status and arrest characteristics, while the effects of in-hospital treatments ... -
A combined histo-score based on tumor differentiation and lymphocytic infiltrate is a robust prognostic marker for mobile tongue cancer
(Journal article; Peer reviewed, 2020-06-30)We wanted to evaluate the prognostic value of common histopathological variables in a large cohort of patients with cancer in the mobile tongue as such information can be important for treatment stratification of the ... -
Computationally efficient familywise error rate control in genome-wide association studies using score tests for generalized linear models
(Journal article; Peer reviewed, 2020)In genetic association studies, detecting phenotype–genotype association is a primary goal. We assume that the relationship between the data—phenotype, genetic markers and environmental covariates—can be modeled by a ... -
Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency
(Journal article; Peer reviewed, 2020)A substantial proportion of patients with common variable immunodeficiency (CVID) have inflammatory and autoimmune complications of unknown etiology. We have previously shown that systemic inflammation in CVID correlates ... -
Elevated plasma cystathionine is associated with increased risk of mortality among patients with suspected or established coronary heart disease
(Journal article; Peer reviewed, 2019)Background Elevated circulating cystathionine levels are related to atherosclerotic cardiovascular disease, a leading cause of death globally. Objective We investigated whether plasma cystathionine was associated with ... -
Operating room ventilation and the risk of revision due to infection after total hip arthroplasty: assessment of validated data in the Norwegian Arthroplasty Register
(Journal article; Peer reviewed, 2020)Background The air in the operating room is considered a risk factor for surgical site infection (SSI) due to airborne bacteria shed from the surgical staff or from patients themselves. Aim To assess the influence of ... -
AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study
(Journal article; Peer reviewed, 2020-07-08)Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor degradation, ... -
Wearing-off at the end of natalizumab dosing intervals is associated with low receptor occupancy
(Journal article; Peer reviewed, 2020-02)Objective: We aimed to investigate whether wearing-off symptoms at the end of the natalizumab dosing interval were associated with clinical and demographic patient characteristics or natalizumab receptor occupancy (RO) on ... -
Universal health coverage of HIV, TB and malaria interventions in Ethiopia: economic burden, health benefits and financial risk protection
(Doctoral thesis, 2021-04-07)Introduction: Human Immunodeficiency Virus (HIV), Tuberculosis (TB) and malaria remain a major threat to the Ethiopian population. In the past decades, substantial gains have been achieved in reducing morbidity and mortality ...
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