• Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy 

  Nielsen, Hans Jørgen; Nedrebø, Bjørn Gunnar; Fosså, Alexander; Andersen, John Roger; Assmus, Jörg; Dagsland, Vigdis Halvorsen; Dankel, Simon N; Gudbrandsen, Oddrun Anita; Fernø, Johan; Hjellestad, Iren Drange; Hjermstad, Marianne Jensen; Kolotkin, Ronette Loganzo; Thorsen, Håvard Luong; Mellgren, Gunnar; Flølo, Tone Nygaard (Journal article; Peer reviewed, 2022)

  Background/objectives There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and ...

• Disease-Course Adapting Machine Learning Prognostication Models in Elderly Patients Critically Ill With COVID-19: Multicenter Cohort Study With External Validation 

  Jung, Christian; Mamandipoor, Behrooz; Fjølner, Jesper; Bruno, Raphael Romano; Wernly, Bernhard; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter V.; Szczeklik, Wojciech; Czuczwar, Miroslaw; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans Kristian; Osmani, Venet (Journal article; Peer reviewed, 2022)

  Background:The COVID-19 pandemic caused by SARS-CoV-2 is challenging health care systems globally. The disease disproportionately affects the elderly population, both in terms of disease severity and mortality risk. ...

• Anti-PD-L1/TGF-βR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer 

  Cheng, Bo; Ding, Kaikai; Chen, Pengxiang; Ji, Jianxiong; Luo, Tao; Guo, Xiaofan; Qiu, Wei; Ma, Chunhong; Meng, Xue; Wang, Jian; Yu, Jinming; Liu, Yuan (Journal article, 2022)

  Background Second-generation programmed cell death-protein 1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors, such as bintrafusp alfa (M7824), SHR-1701, and YM101, have been developed to simultaneously block PD-1/PD-L1 ...

• Changes in eicosapentaenoic acid and docosahexaenoic acid and risk of cardiovascular events and atrial fibrillation: A secondary analysis of the OMEMI trial 

  Myhre, Peder Langeland; Kalstad, Are; Tveit, Sjur Hansen; Laake, Kristian; Schmidt, Erik B.; Smith, Pål; Nilsen, Dennis W.T.; Tveit, Arnljot; Solheim, Svein; Arnesen, Harald; Seljeflot, Ingebjørg (Journal article; Peer reviewed, 2022)

  Background The cardiovascular benefit from n-3 polyunsaturated fatty acids (PUFAs) after acute myocardial infarction (AMI) is controversial, and the importance of serum eicosapentaenoic acid (EPA) and docosahexaenoic acid ...

• The effect of gadolinium-based contrast-agents on automated brain atrophy measurements by FreeSurfer in patients with multiple sclerosis 

  Lie, Ingrid Anne; Kerklingh, Emma; Wesnes, Kristin; van Nederpelt, David R.; Brouwer, Iman; Torkildsen, Øivind; Myhr, Kjell-Morten; Barkhof, Frederik; Bø, Lars; Vrenken, Hugo (Journal article; Peer reviewed, 2022)

  Objective To determine whether reliable brain atrophy measures can be obtained from post-contrast 3D T1-weighted images in patients with multiple sclerosis (MS) using FreeSurfer. Methods Twenty-two patients with MS ...

• In-office thermal systems for the treatment of dry eye disease 

  Beining, Marie Wangen; Magnø, Morten Scherven; Moschowits, Emily; Olafsson, Jonatan; Vehof, Jelle; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2022)

  Dry eye disease affects millions of people worldwide, causing pain, vision disturbance, and reduced productivity. Meibomian gland dysfunction, a major cause of dry eye, is characterized by chronic glandular inflammation, ...

• Placental weight centiles adjusted for age, parity and fetal sex 

  Flatley, Christopher; Sole-Navais, Pol; Vaudel, Marc; Helgeland, Øyvind; Modzelewska, Dominika; Johansson, Stefan; Jacobsson, Bo; Njølstad, Pål Rasmus (Journal article; Peer reviewed, 2022)

  Introduction The weight of the placenta can be indicative of efficacy in nutrient and oxygen supply. Furthermore, it has been suggested that a measure of the placenta's ability to adequately supply nutrients to the fetus ...

• Identification of microRNAs from medicinal plant Murraya Koenigii by high-throughput sequencing and their functional implications in secondary metabolite biosynthesis 

  Gutiérrez-García, Claudia; Ahmed, Shiek S. S. J.; Ramalingam, Sathishkumar; Selvaraj, Dhivya; Srivastava, Aashish; Paul, Sujay; Sharma, Ashutosh (Journal article; Peer reviewed, 2022)

  MicroRNAs (miRNAs) are small noncoding RNA molecules that play crucial post-transcriptional regulatory roles in plants, including development and stress-response signaling. However, information about their involvement in ...

• Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction 

  Mundal, Siv Boon; Rakner, Johanne Johnsen; Silva, Gabriela; Gierman, Lobke; Austdal, Marie; Basnet, Purusotam; Elschot, Mattijs; Bakke, Siril Skaret; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Moses, Eric; Acharya, Ganesh; Bjørge, Line; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2022)

  Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are ...

• Association of Excessive Sleepiness, Pathological Fatigue, Depression, and Anxiety With Different Severity Levels of Obstructive Sleep Apnea 

  Mjelle, Karin Elisabeth Sundt; Lehmann, Sverre; Saxvig, Ingvild W.; Gulati, Shashi; Bjorvatn, Bjørn (Journal article; Peer reviewed, 2022-03-31)

  Objective: The aim of this study was to investigate possible associations between obstructive sleep apnea and fatigue. This naturally led to considering the association between OSA and excessive sleepiness, depression, and ...

• Basosquamous Basal Cell Carcinoma with Bone Marrow Metastasis 

  Thunestvedt, Lise Mayrin Økland; Helgeland, Lars; Bachmann, Ingeborg Margrethe; Karlsdottir, Åsa; Haslerud, Torjan Magne; Reikvam, Håkon (Journal article; Peer reviewed, 2022-03-23)

  Basal cell carcinoma (BCC) is the most common cancer in Caucasians. It is slow growing and rarely metastasizes. If left untreated over time, invasive growth can occur. We present a patient case with a primary BCC located ...

• Lifelong exposure to residential greenspace and the premenstrual syndrome: A population-based study of Northern European women 

  Triebner, Kai Philipp; Markevych, Iana; Bertelsen, Randi Jacobsen; Skottvoll, Bente Sved; Hustad, Simon Steinar; Forsberg, Bertil; Franklin, Karl A; Holm, Mathias; Lindberg, Eva; Heinrich, Joachim; Real, Francisco Gomez; Dadvand, Payam (Journal article; Peer reviewed, 2022)

  Background: The premenstrual syndrome (PMS) causes clinically relevant psychological and physical symptoms in up to 20% of women of reproductive age. To date, no studies have investigated the relationship between PMS and ...

• New Evidence About Aortic Valve Stenosis and Cardiovascular Hemodynamics 

  Mancusi, Costantino; Bahlmann, Edda; Basile, Christian; Gerdts, Eva (Journal article; Peer reviewed, 2022)

  Aortic stenosis (AS) is the most common degenerative valvular disease in western word. In patients with severe AS, small changes in aortic valve area can lead to large changes in hemodynamics. The correct understanding of ...

• I tiden etter pasientsikkerhetsprogrammet - En studie om varig endring i spesialisthelsetjenesten 

  Dahler, Anders (Master thesis, 2022-05-31)

  Helsevesenet er i stadig endring, det er derfor svært viktig at helsevesenet evner å gjøre effektive endringer som varer. Det er gjort mye forskning på hva som skal til for at en virksomhet skal endre seg, men det har ...

• Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study 

  Grindheim, Sindre; Ebbing, Cathrine; Karlsen, Henriette Odland; Skulstad, Svein Magne; Real, Francisco Gomez; Lønnebotn, Marianne; Løvvik, Tone Shetelig; Vanky, Eszter; Kessler, Jørg (Journal article; Peer reviewed, 2022-01-28)

  Background: Metformin is prescribed to women with polycystic ovary syndrome (PCOS) to prevent pregnancy complications. Children exposed to metformin vs. placebo in utero, have increased head circumference at birth and are ...

• Vagally mediated heart rate variability, stress, and perceived social support: a focus on sex differences 

  Kvadsheim, Elisabet; Sørensen, Lin; Fasmer, Ole Bernt; Osnes, Berge; Haavik, Jan; Williams, DeWayne P.; Thayer, Julian Francis; Koenig, Julian (Journal article; Peer reviewed, 2022)

  Higher vagally mediated heart rate variability (vmHRV), reflecting vagal activity as indexed by heart function and lower stress vulnerability, is associated with higher perceived social support. Seeking social support is ...

• Thulium Fibre Laser versus Holmium:YAG for Ureteroscopic Lithotripsy: Outcomes from a Prospective Randomised Clinical Trial 

  Ulvik, Øyvind; Æsøy, Mathias S.; Jones, Charles Patrick Warburton; Gjengstø, Peder; Beisland, Christian (Journal article; Peer reviewed, 2022)

  Background Holmium:yttrium-aluminium-garnet (Ho:YAG) laser is the gold standard for ureterorenoscopic (URS) lithotripsy. Thulium fibre laser (TFL) has recently been introduced as a new technology and may challenge Ho:YAG ...

• Aiming towards evidence based interpretation of cardiac biomarkers in patients presenting with chest pain : The WESTCOR study 

  Tjora, Hilde Lunde (Doctoral thesis, 2022-08-23)

  Bakgrunn: Ca 10% av alle pasientar i akuttmottak blir innlagt med brystsmerter og spørsmål om akutt koronarsyndrom (AKS), men under ¼ av pasientane har AKS. Metode:WESTCOR studien er ein prospektiv observasjonsstudie som ...

• Development and feasibility testing of a physical activity intervention for youth with anxiety and depression: a study protocol 

  Kodal, Arne; Muirhead, Fiona; Reilly, John J.; Wergeland, Gro Janne Henningsen; Thorsen, Paul Joachim Bloch; Bovim, Lars Peder Vatshelle; Elgen, Irene Bircow (Journal article; Peer reviewed, 2022)

  Background Anxiety and depressive disorders in children and adolescents are highly prevalent and account for more than half of all youth psychiatric disorders. Left untreated, anxiety, and depression lead to numerous ...

• Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases 

  Jellas, Khadija el; Dušátková, Petra; Haldorsen, Ingfrid S.; Molnes, Janne; Tjora, Erling; Johansson, Bente Berg; Fjeld, Karianne; Johansson, Stefan; Průhová, Štěpánka; Groop, Leif; Löhr, J. Matthias; Njølstad, Pål Rasmus; Molven, Anders (Journal article; Peer reviewed, 2022)

  Context Maturity onset diabetes of the young, type 8 (MODY8) is associated with mutations in the CEL gene, which encodes the digestive enzyme carboxyl ester lipase. Several diabetes cases and families have in recent years ...

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