• The unmet need for treatment of children with musculoskeletal impairment in Malawi 

  Ngoie, Leonard Banza; Dybvik, Eva Hansen; Hallan, Geir; Gjertsen, Jan-Erik; Mkandawire, Nyengo; Varela, Carlos Gomes; Young, Sven (Journal article; Peer reviewed, 2022)

  Background More than a billion people globally are living with disability and the prevalence is likely to increase rapidly in the coming years in low- and middle-income countries (LMICs). The vast majority of those living ...

• Structural and biophysical characterization of transcription factor HNF-1A as a tool to study MODY3 diabetes variants 

  Kind, Laura; Raasakka, Arne; Molnes, Janne; Aukrust, Ingvild; Bjørkhaug, Lise; Njølstad, Pål Rasmus; Kursula, Petri; Arnesen, Thomas (Journal article; Peer reviewed, 2022)

  Hepatocyte nuclear factor 1A (HNF-1A) is a transcription factor expressed in several embryonic and adult tissues, modulating the expression of numerous target genes. Pathogenic variants in the HNF1A gene are known to cause ...

• An exploration of the sustainability of dinner recipes 

  Angelsen, Aslaug Linnea (Master thesis, 2022-05-13)

• Modifiable cardiovascular disease risk factors among adults in southern Ethiopia: a community-based cross-sectional study 

  Kumma, Wondimagegn Paulos; Lindtjorn, Bernt; Loha, Eskindir (Journal article; Peer reviewed, 2022)

  Objective To assess the prevalence, magnitude and factors associated with the number of major modifiable cardiovascular disease (CVD) risk factors. Design Community-based cross-sectional study. Setting General ...

• Contribution of an extensive medication-based comorbidity index (Rx-Risk) in explaining the excess mortality after hip fracture in older Norwegians: a NOREPOS cohort study 

  Holvik, Kristin; Hjellvik, Vidar; Karlstad, Øystein; Gunnes, Nina; Hoff, Mari; Tell, Grethe Seppola; Meyer, Haakon Eduard (Journal article; Peer reviewed, 2022)

  Objectives Patients with hip fracture are typically characterised by extensive comorbidities and excess mortality. Methods that account for a wide range of comorbidities are needed when attempting to identify causal ...

• Evolution and dispersal of mitochondrial DNA haplogroup U5 in Northern Europe: insights from an unsupervised learning approach to phylogeography 

  Kristjansson, Dana; Bohlin, Jon; Nguyen, Truc Trung; Jugessur, Astanand; Schurr, Theodore G. (Journal article; Peer reviewed, 2022)

  Background We combined an unsupervised learning methodology for analyzing mitogenome sequences with maximum likelihood (ML) phylogenetics to make detailed inferences about the evolution and diversification of mitochondrial ...

• Association between medical androgen deprivation therapy and long-term cardiovascular disease and all-cause mortality in nonmetastatic prostate cancer 

  Forster, Rachel Bedenis; Engeland, Anders; Kvåle, Rune; Hjellvik, Vidar; Bjørge, Tone (Journal article; Peer reviewed, 2022)

  Studies have suggested that prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) are at increased risk of developing or exacerbating cardiovascular disease (CVD). We aimed to explore the association ...

• Nine-fold higher risk of acute myocardial infarction in subjects with type 1 diabetes compared to controls in Norway 1973–2017 

  Saeed, Maryam; Stene, Lars Christian Mørch; Ariansen, Inger Kristine Holtermann; Tell, Grethe S.; Tapia, German; Joner, Geir; Skrivarhaug, Torild (Journal article; Peer reviewed, 2022)

  Background We aimed to study the cumulative incidence and risk factors (sex, age, calendar year of diabetes onset, country of origin and educational level) of acute myocardial infarction (AMI) in subjects with type 1 ...

• Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial 

  Clemm, Hege Synnøve Havstad; Røksund, Ola Drange; Andersen, Tiina Maarit; Heimdal, John-Helge; Karlsen, Tom; Hilland, Magnus; Fretheim-Kelly, Zoe; Hufthammer, Karl Ove; Sandnes, Astrid; Hjelle, Sigrun Margrethe; Vollsæter, Maria; Halvorsen, Thomas (Journal article; Peer reviewed, 2022)

  Background: Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young individuals, caused by paradoxical inspiratory adduction of laryngeal structures, and diagnosed by ...

• Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study 

  Hernáez, Álvaro; Wootton, Robyn E; Page, Christian Magnus; Skåra, Karoline Hansen; Fraser, Abigail; Rogne, Tormod; Magnus, Per Minor; Njølstad, Pål Rasmus; Andreassen, Ole; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Journal article; Peer reviewed, 2022)

  Objective To investigate the association between smoking and infertility. Design Prospective study. Setting Nationwide cohort. Patients 28,606 women and 27,096 men with questionnaire and genotype information ...

• Night shift work, chemical coexposures and risk of female breast cancer in the Norwegian Offshore Petroleum Workers (NOPW) cohort: a prospectively recruited case-cohort study 

  Liu, Fei-Chih; Veierød, Marit Bragelien; Kjærheim, Kristina; Robsahm, Trude Eid; Ghiasvand, Reza; Hosgood, H Dean; Samuelsen, Sven Ove; Bråtveit, Magne; Kirkeleit, Jorunn; Rothman, Nathaniel; Lan, Qing; Silverman, Debra T; Friesen, Melissa C; Babigumira, Ronnie; Shala, Nita Kaupang; Grimsrud, Tom Kristian; Stenehjem, Jo S. (Journal article; Peer reviewed, 2022)

  Objectives This study examined the association between night shift work and risk of breast cancer, overall and by hormone receptor subtype, among females in the Norwegian Offshore Petroleum Workers (NOPW) cohort. We also ...

• Is the risk of cardiovascular disease in women with pre-eclampsia modified by very low or very high offspring birth weight? A nationwide cohort study in Norway 

  Riise, Hilde Kristin Refvik; Igland, Jannicke; Sulo, Gerhard; Iversen, Marjolein M.; Graue, Marit; Eskild, Anne; Tell, Grethe S.; Daltveit, Anne Kjersti Nesje (Journal article; Peer reviewed, 2022)

  Objectives To examine whether the risk of cardiovascular disease (CVD) in women with pre-eclampsia is modified by very low or very high offspring birth weight. Further, we studied whether diabetes in pregnancy modified ...

• Mechanical stress shapes the cancer cell response to neddylation inhibition 

  Mittler, Frédérique; Obeïd, Patricia; Haguet, Vincent; Allier, Cédric; Gerbaud, Sophie; Rulina, Anastasiia; Gidrol, Xavier; Balakirev, Maxim Y. (Journal article; Peer reviewed, 2022)

  Background The inhibition of neddylation by the preclinical drug MLN4924 represents a new strategy to combat cancer. However, despite being effective against hematologic malignancies, its success in solid tumors, where ...

• A nationwide study of the incidence, prevalence and mortality of Parkinson’s disease in the Norwegian population 

  Brakedal, Brage; Toker, Lilah; Haugarvoll, Kristoffer; Tzoulis, Charalampos (Journal article; Peer reviewed, 2022)

  Epidemiological studies of Parkinson’s disease (PD) show variable and partially conflicting findings with regard to incidence, prevalence, and mortality. These differences are commonly attributed to technical and methodological ...

• Team reflexivity and the shared mind in interprofessional learning 

  Baerheim, Anders; Ødegaard, Elin Eriksen; Ness, Ingunn Johanne (Journal article; Peer reviewed, 2022)

  In interprofessional (IP) workplace education, course and project leaders need a deeper understanding of how students learn. Basically, in IP workplace learning students learn from each other, from the affected agents ...

• Survival of children with rare structural congenital anomalies: a multi-registry cohort study 

  Coi, Alessio; Santoro, Michele; Pierini, Anna; Rankin, Judith; Glinianaia, Svetlana V.; Tan, Joachim; Reid, Abigail-Kate; Garne, Ester; Loane, Maria; Given, Joanne; Ballardini, Elisa; Cavero-Carbonell, Clara; de Walle, Hermien E.K.; Gatt, Miriam; García-Villodre, Laura; Gissler, Mika; Jordan, Sue; Kiuru-Kuhlefelt, Sonja; Kjaer Urhoj, Stine; Klungsøyr, Kari; Lelong, Nathalie; Lutke, L. Renée; Neville, Amanda J.; Rahshenas, Makan; Scanlon, Ieuan; Wellesley, Diana; Morris, Joan K. (Journal article; Peer reviewed, 2022)

  Background Congenital anomalies are the leading cause of perinatal, neonatal and infant mortality in developed countries. Large long-term follow-up studies investigating survival beyond the first year of life in children ...

• Genome-wide association meta-analysis of childhood and adolescent internalizing symptoms 

  Jami, Eshim S.; Hammerschlag, Anke R.; Ip, Hill F.; Allegrini, Andrea G.; Benyamin, Beben; Border, Richard; Diemer, Elizabeth W.; Jiang, Chang; Karhunen, Ville; Lu, Yi; Lu, Qing; Mallard, Travis T.; Mishra, Pashupati P.; Nolte, Ilja M.; Palviainen, Teemu; Peterson, Roseann E.; Sallis, Hannah M.; Shabalin, Andrey A.; Tate, Ashley E.; Thiering, Elisabeth; Vilor-Tejedor, Natàlia; Wang, Carol; Zhou, Ang; Adkins, Daniel E.; Alemany, Silvia; Ask, Helga; Chen, Qi; Corley, Robin P.; Ehli, Erik A.; Evans, Luke M.; Havdahl, Alexandra; Hagenbeek, Fiona A.; Hakulinen, Christian; Henders, Anjali K.; Hottenga, Jouke Jan; Korhonen, Tellervo; Mamun, Abdullah; Marrington, Shelby; Neumann, Alexander; Rimfeld, Kaili; Rivadeneira, Fernando; Silberg, Judy L.; van Beijsterveldt, Catharina E.; Vuoksimaa, Eero; Whipp, Alyce M.; Tong, Xiaoran; Andreassen, Ole; Boomsma, Dorret I.; Brown, Sandra A.; Burt, S. Alexandra; Copeland, William; Dick, Danielle M.; Harden, K. Paige; Harris, Kathleen Mullan; Hartman, Catharina A.; Heinrich, Joachim; Hewitt, John K.; Hopfer, Christian; Hypponen, Elina; Jarvelin, Marjo-Riitta; Kaprio, Jaakko; Keltikangas-Järvinen, Liisa; Klump, Kelly L.; Krauter, Kenneth; Kuja-Halkola, Ralf; Larsson, Henrik; Lehtimäki, Terho; Lichtenstein, Paul; Lundström, Sebastian; Maes, Hermine H.; Magnus, Per Minor; Munafò, Marcus R.; Najman, Jake M.; Njølstad, Pål Rasmus; Oldehinkel, Albertine J.; Pennell, Craig E.; Plomin, Robert; Reichborn-Kjennerud, Ted; Reynolds, Chandra; Rose, Richard J.; Smolen, Andrew; Snieder, Harold; Stallings, Michael; Standl, Marie; Sunyer, Jordi; Tiemeier, Henning; Wadsworth, Sally J.; Wall, Tamara L.; Whitehouse, Andrew J.O.; Williams, Gail M.; Ystrøm, Eivind; Nivard, Michel G.; Bartels, Meike; Middeldorp, Christel M. (Journal article; Peer reviewed, 2022)

  Objective: To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. Method: In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated ...

• Tracking of lung function from 10 to 35 years after being born extremely preterm or with extremely low birth weight 

  Bårdsen, Tonje; Røksund, Ola Drange; Benestad, Merete; Hufthammer, Karl Ove; Clemm, Hege Synnøve Havstad; Mikalsen, Ingvild Bruun; Øymar, Knut Asbjørn Alexander; Markestad, Trond Jacob; Halvorsen, Thomas; Vollsæter, Maria (Journal article; Peer reviewed, 2022)

  Background Lifelong pulmonary consequences of being born extremely preterm or with extremely low birth weight remain unknown. We aimed to describe lung function trajectories from 10 to 35 years of age for individuals ...

• Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function 

  Ishizuka, Yuta; Mergiya, Tadiwos Feyissa; Baldinotti, Rodolfo Da Silva Mazzarini; Xu, Ju; Hallin, Erik Ingmar; Markusson, Sigurbjörn; Kursula, Petri; Bramham, Clive Raymond Evjen (Journal article; Peer reviewed, 2022)

  Activity-regulated cytoskeleton-associated (Arc) protein plays key roles in long-term synaptic plasticity, memory, and cognitive flexibility. However, an integral understanding of Arc mechanisms is lacking. Arc is proposed ...

• Ankle fractures: a systematic review of patient‑reported outcome measures and their measurement properties 

  Nguyen, Michael Quan; Dalen, Ingvild; Iversen, Marjolein Memelink; Harboe, Knut; Paulsen, Aksel (Journal article; Peer reviewed, 2022)

  Purpose Ankle fractures are commonly occurring fractures, especially in the aging population, where they often present as fragility fractures. The disease burden and economic costs to the patient and society are considerable. ...

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