Nye registreringer

  • Wavelet Screening identifies regions highly enriched for differentially methylated loci for orofacial clefts 

    Denault, William Robert Paul; Romanowska, Julia; Haaland, Øystein Ariansen; Lyle, Robert; Taylor, Jack A.; Xu, Zongli; Lie, Rolv T.; Gjessing, Håkon K.; Jugessur, Astanand (Journal article; Peer reviewed, 2021)
    DNA methylation is the most widely studied epigenetic mark in humans and plays an essential role in normal biological processes as well as in disease development. More focus has recently been placed on understanding ...
  • Novel preoperative biomarkers and evaluation of altered treatment strategies to improve outcome for endometrial cancer patients 

    Forsse, David (Doctoral thesis, 2021-10-01)
    Background: Endometrial cancer is the most common gynecological cancer among women in countries with a high developmental index, and the incidence is expected to rise. Major controversies in the treatment of endometrial ...
  • Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors 

    Torgersen, Kristin Stensland; Bahrami, Shahram; Frei, Oleksandr; Shadrin, Alexey; O'Connell, Kevin Sean; Smeland, Olav Bjerkehagen; Munkhaugen, John; Djurovic, Srdjan; Dammen, Toril; Andreassen, Ole A. (Journal article; Peer reviewed, 2021)
    Neuroticism is associated with poor health, cardiovascular disease (CVD) risk factors and coronary artery disease (CAD). The conditional/conjunctional false discovery rate method (cond/conjFDR) was applied to genome wide ...
  • Studies of gene expression in the Parkinson’s disease brain 

    Dick, Fiona (Doctoral thesis, 2021-10-01)
    Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder, affecting ~1.8% of the population above 65 years. A combination of genetic and environmental factors contributes to the risk of PD, but the ...
  • Preference-based instrumental variables in health research rely on important and underreported assumptions: a systematic review 

    Widding-Havneraas, Tarjei; Chaulagain, Ashmita; Lyhmann, Ingvild; Zachrisson, Henrik Daae; Elwert, Felix; Markussen, Simen; McDaid, David; Mykletun, Arnstein (Journal article; Peer reviewed, 2021)
    Objective: Preference-based instrumental variables (PP IV) designs can identify causal effects when patients receive treatment due to variation in providers’ treatment preference. We offer a systematic review and methodological ...
  • 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans 

    Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi; Ellegaard, Maria; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Bøen, Rune; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Ching, Christopher R. K.; Cichon, Sven; Ciufolini, Simone; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dale, Anders M.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J. C.; Zubicaray, Greig I. de; Zwarte, Sonja M. C. de; Desrivieres, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fejgin, Kim; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Haberg, Asta Kristine; Hall, Jeremy; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek P.; Hillegers, Manon H. J.; Hoffmann, Per; Holleran, Laurena; Holmes, Avram J.; Johansson, Stefan; Jönsson, Erik Gunnar; Hellard, Stephanie Francoise Claire Le; Lundervold, Arvid; Lundervold, Astri J.; Moberget, Torgeir; Nordvik, Jan Egil; Sando, Sigrid Botne; Steen, Vidar Martin; Tamnes, Christian Krog; Agartz, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole; Homuth, Georg; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Ikeda, Masashi; Jahanshad, Neda; Jockwitz, Christiane; Jørgensen, Niklas R.; Kikuchi, Masataka; Knowles, Emma E. M.; Kumar, Kuldeep; Leu, Costin; Linden, David E. J.; Liu, Jingyu; Maillard, Anne M.; Martin, Nicholas G.; Martin-Brevet, Sandra; Mather, Karen A.; Mathias, Samuel R.; McMahon, Katie L.; McRae, Allan F.; Medland, Sarah E.; Meyer-Lindenberg, Andreas; Modenato, Claudia; Monereo Sánchez, Jennifer; Morris, Derek W.; Mühleisen, Thomas W.; Murray, Robin M.; Nielsen, Jacob; Nyberg, Lars; Olde Loohuis, Loes M.; Ophoff, Roel A.; Owen, Michael J.; Paus, Tomas; Pausova, Zdenka; Peralta, Juan M.; Pike, G. Bruce; Prieto, Carlos; Quinlan, Erin B.; Reinbold, Céline S.; Reis Marques, Tiago; Rucker, James J. H.; Sachdev, Perminder S.; Schofield, Peter R.; Schork, Andrew J.; Schumann, Gunter; Shin, Jean; Shumskaya, Elena; Silva, Ana I.; Sisodiya, Sanjay M.; Stein, Dan J.; Strike, Lachlan T.; Suzuki, Ikuo K.; Teumer, Alexander; Thalamuthu, Anbupalam; Tordesillas-Gutiérrez, Diana; Uhlmann, Anne; Ulfarsson, Magnus O.; van ‘t Ent, Dennis; van den Bree, Marianne B. M.; Vanderhaeghen, Pierre; Vassos, Evangelos; Wen, Wei; Wittfeld, Katharina; Wright, Margaret J.; Stefansson, Hreinn; Stefansson, Kari; Jacquemont, Sébastien; Thompson, Paul M. (Journal article; Peer reviewed, 2021)
    Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...
  • Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response 

    Akkouh, Ibrahim; Hribkova, Hana; Grabiec, Marta; Budinska, Eva; Szabo, Attila; Kasparek, Tomas; Andreassen, Ole Andreas; Sun, Yuh-Man; Djurovic, Srdjan (Journal article; Peer reviewed, 2021)
    Astrocytes are the most abundant cell type in the human brain and are important regulators of several critical cellular functions, including synaptic transmission. Although astrocytes are known to play a central role in ...
  • Role of integrin α11β1 in breast cancer 

    Smeland, Hilde Ytre-Hauge (Doctoral thesis, 2021-09-24)
    Breast cancer cells are strongly influenced by a complex tumor microenvironment comprised of a diversity of stromal cells, including a heterogeneous population of cancer associated fibroblasts (CAFs), in addition to the ...
  • Gastric dysmotility and visceral hypersensitivity – an ultrasound approach to functional GI disorders and diabetic gastroparesis 

    Steinsvik, Elisabeth Kjelsvik (Doctoral thesis, 2021-09-24)
    Background: Functional dyspepsia (FD), irritable bowel syndrome (IBS) and diabetic gastroparesis (DG) are conditions with overlapping symptoms and motility characteristics. The objective of this dissertation was to investigate ...
  • Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank 

    O'Connell, Kevin S.; Sønderby, Ida Elken; Frei, Oleksandr; van der Meer, Dennis; Athanasiu, Lavinia; Smeland, Olav Bjerkehagen; Alnæs, Dag; Kaufmann, Tobias; Westlye, Lars Tjelta; Steen, Vidar Martin; Andreassen, Ole Andreas; Hughes, Timothy; Djurovic, Srdjan (Journal article; Peer reviewed, 2021)
    Background Altered expression of the complement component C4A gene is a known risk factor for schizophrenia. Further, predicted brain C4A expression has also been associated with memory function highlighting that altered ...
  • The anatomic centers of the femoral and tibial insertions of the anterior cruciate ligament: a systematic review of imaging and cadaveric studies reporting normal center locations 

    Parkar, Anagha P; Adriaensen, Miraude E.A.M.P.; Vindfeld, Søren; Solheim, Eirik (Journal article; Peer reviewed, 2016)
    Background: The anterior cruciate ligament (ACL) is regularly reconstructed if knee joint function is impaired. Anatomic graft tunnel placement, often assessed with varying measurement methods, in the femur and tibia is ...
  • Sex-Specific Associations between Blood Pressure and Risk of Atrial Fibrillation Subtypes in the Tromsø Study 

    Espnes, Hilde; Ball, Jocasta; Løchen, Maja-Lisa; Wilsgaard, Tom; Njølstad, Inger; Mathiesen, Ellisiv B; Gerdts, Eva; Sharashova, Ekaterina (Journal article; Peer reviewed, 2021)
    The aim of this study was to explore sex-specific associations between systolic blood pressure (SBP), hypertension, and the risk of incident atrial fibrillation (AF) subtypes, including paroxysmal, persistent, and permanent ...
  • Challenges in diagnosis and treatment of extrapulmonary tuberculosis 

    Hoel, Ida Marie (Doctoral thesis, 2021-09-23)
    The infectious disease tuberculosis (TB) is a global health problem. Diagnosis of extrapulmonary TB is often challenging due to non-specific symptoms and findings, and the lack of sensitive diagnostic tests. This leads to ...
  • Changes in health among Syrian refugees : A prospective study along the migration trajectories from the Middle East to Northern Europe 

    Strømme, Elisabeth Marie (Doctoral thesis, 2021-09-24)
    Background: In the wake of unprecedented numbers of individuals forced to flee due to persecution, conflict, and other human rights violations over the past decade, health implications of forced displacement have become ...
  • Short-term outcome after open-heart surgery for severe chronic rheumatic heart disease in a low-income country, with comparison with an historical control group: an observational study 

    Hauge, Ståle Wågen; Dalen, Havard; Estensen, Mette-Elise; Persson, Robert Matongo; Abebe, Sintayehu; Mekonnen, Desalew; Nega, Berhanu; Solholm, Atle; Farstad, Marit; Bogale, Nigussie; Graven, Torbjorn; Nielssen, Niels-Erik; Brekke, Hege Kristin; Vikenes, Kjell; Haaverstad, Rune (Journal article; Peer reviewed, 2021)
    Objectives Rheumatic heart disease (RHD) is a major burden in low-income and middle-income countries (LMICs). Cardiac surgery is the only curative treatment. Little is known about patients with severe chronic RHD operated ...
  • ISUOG Practice Guidelines (updated): use of Doppler velocimetry in obstetrics 

    Bhide, Amarnath; Acharya, Ganesh; Baschat, Ahmet Alexander; Bilardo, Caterina Maddalena; Brezinka, Christoph; Cafici, Daniel; Ebbing, Cathrine; Hernandez-Andrade, Edgar A.; Kalache, Karim; Kingdom, John; Kiserud, Torvid; Surendran, Sailesh Kumar; Lee, Wesley; Lees, Christoph; Leung, Kwok Yin; Malinger, Gustavo; Mari, Giancarlo; Prefumo, Federico; Sepulveda, Waldo; Trudinger, Brian (Journal article; Peer reviewed, 2021)
  • Overexpression of mir-20a-5p in tumor epithelium is an independent negative prognostic indicator in prostate cancer—a multi-institutional study 

    Stoen, Maria J.; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona I.; Ingebriktsen, Lise M.; Dønnem, Tom; Lombardi, Ana P. G.; Kilvaer, Thomas K.; Rasmussen Busund, Lill-Tove; Richardsen, Elin (Journal article; Peer reviewed, 2021)
    Objective: assessing the prognostic role of miR-20a-5p, in terms of clinical outcome, in a large multi-institutional cohort study. Methods: Tissue microarrays from 535 patients’ prostatectomy specimens were constructed. ...
  • Dyspnea, lung function and CT findings three months after hospital admission for COVID-19 

    Lerum, Tøri Vigeland; Aaløkken, Trond M; Brønstad, Eivind; Aarli, Bernt Bøgvald; Ikdahl, Eirik; Lund, Kristine Marie Aarberg; Durheim, Michael; Rivero, Jezabel Rodriguez; Meltzer, Carin; Tonby, Kristian; Stavem, Knut; Skjønsberg, Ole Henning; Ashraf, Haseem; Einvik, Gunnar (Journal article; Peer reviewed, 2021)
    The long-term pulmonary outcomes of coronavirus disease 2019 (COVID-19) are unknown. We aimed to describe self-reported dyspnoea, quality of life, pulmonary function and chest computed tomography (CT) findings 3 months ...
  • Fetal Superior Vena Cava Blood Flow and Its Fraction of Cardiac Output: A Longitudinal Ultrasound Study in the Second Half of Pregnancy 

    Stefopoulou, Maria; Johnson, Jonas; Herling, Lotta; Lindgren, Peter; Kiserud, Torvid; Acharya, Ganesh (Journal article; Peer reviewed, 2021)
    Introduction: In the fetus, a large proportion of the superior vena cava blood flow (QSVC) comes from the brain. To provide the possibility of using this blood flow as a representation of fetal brain circulation, we aimed ...

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