Faculty of Medicine
Recent Submissions
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´A storehouse of mother´s unconditional love and nectar´- The role of the National Comprehensive Lactation Management Centre in strengthening feeding of premature infants in New Delhi, India
(Master thesis, 2021-12-15)Introduction: Providing human milk to sick- and premature infants is a lifesaving intervention that alone can reduce neonatal mortality. Studies have shown that donor human milk is the second-best alternative after mother’s ... -
Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of infammation measured three months after ischemic stroke
(Journal article; Peer reviewed, 2021)Background Chronic low-grade inflammation is associated with both ischemic stroke and sedentary behaviour. The aim of this study was to investigate the predictive abilities of biomarkers of inflammation and immune modulation ... -
Rules and regulations for a pregnant endourologist: the European perspective
(Journal article; Peer reviewed, 2021)Introduction Working in surgery while pregnant is challenging. Navigating this period safely is of paramount importance. Anecdotal observation suggests that there exists great variation among European nations in regard ... -
Health equity impact of community-initiated kangaroo mother care: a randomized controlled trial
(Journal article; Peer reviewed, 2021)Background Kangaroo mother care (KMC) can substantially enhance overall survival of low birthweight babies. In a large randomized controlled trial, we recently showed that supporting mothers to provide community initiated ... -
Current Status of Intravesical Therapies for Bladder Pain Syndrome (BPS): A Narrative Review of Emerging Evidence
(Journal article; Peer reviewed, 2021)Bladder pain syndrome (BPS) is a complex condition, which can have debilitating sequelae for patients. Many elements of BPS remain poorly understood including pathophysiology, diagnosis and treatment. Navigating patient ... -
Conditioned Medium from Bone Marrow Mesenchymal Stem Cells Restored Oxidative Stress-Related Impaired Osteogenic Differentiation
(Journal article; Peer reviewed, 2021)Oxidative stress from high levels of intracellular reactive oxygen species (ROS) has been linked to various bone diseases. Previous studies indicate that mesenchymal stem cells (MSC) secrete bioactive factors (conditioned ... -
General practitioners not available – out-of-hospital emergency patients handled by anaesthesiologist in a large Norwegian municipality
(Journal article; Peer reviewed, 2021)Background Until autumn 2018 the GPs in Bergen Municipality did not attend emergency patients outside the emergency primary care centre. The ambulance staff handled emergencies on their own or were assisted by an ... -
Caries experience by socio-behavioural characteristics in HIV-1-infected and uninfected Ugandan mothers – a multilevel analysis
(Journal article; Peer reviewed, 2021)Objectives To assess caries experience in Ugandan mothers according to HIV status, socio-behavioural-characteristics, gingival bleeding status and to examine whether HIV status impacts the association of socio-behavioural ... -
Characterization of immune cell infiltrate in tumor stroma and epithelial compartments in oral squamous cell carcinomas of Sudanese patients
(Journal article; Peer reviewed, 2021)Background Tumor immune infiltrate has been explored in oral squamous cell carcinoma (OSCC), but studies on simultaneous characterization of multiple immune cell subtypes separately in stromal and intraepithelial tumor ... -
BRCA1 Norway: comparison of classifcation for BRCA1 germline variants detected in families with suspected hereditary breast and ovarian cancer between different laboratories
(Journal article; Peer reviewed, 2022)Pathogenic germline variants in Breast cancer susceptibility gene 1 (BRCA1) predispose carriers to hereditary breast and ovarian cancer (HBOC). Through genetic testing of patients with suspected HBOC an increasing number ... -
Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia
(Journal article; Peer reviewed, 2021)We generated ex vivo drug-response and multiomics profiling data for a prospective series of 252 samples from 186 patients with acute myeloid leukemia (AML). A functional precision medicine tumor board (FPMTB) integrated ... -
Chemical diversity and cellular effects of antifungal cyclic lipopeptides from cyanobacteria
(Journal article; Peer reviewed, 2021)Cyanobacteria produce a variety of chemically diverse cyclic lipopeptides with potent antifungal activities. These cyclic lipopeptides have an amphipathic structure comprised of a polar peptide cycle and hydrophobic fatty ... -
Assessment of markers of gut integrity and inflammation in non-celiac gluten sensitivity after a gluten free-diet
(Journal article; Peer reviewed, 2021)Purpose: Markers for gut integrity and inflammation have received increasing interest as intestinal permeability and innate immune system activation are suggested as possible pathophysiological mechanisms in non-celiac ... -
Climate change and health in Ethiopia: To what extent have the health dimensions of climate change been integrated into the Climate‐Resilient Green Economy?
(Journal article; Peer reviewed, 2021)Ethiopia is experiencing an increasing frequency and intensity of slow-onset and acute disasters caused by climate change, with significant health impacts. Understanding and addressing these impacts involves trade-offs, ... -
AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model
(Journal article; Peer reviewed, 2021)AXL tyrosine kinase activation enhances cancer cell survival, migration, invasiveness, and promotes drug resistance. AXL overexpression is typically detected in a high percentage of renal cell carcinomas (RCCs) and is ... -
The efectiveness of exercise therapy and education plus cognitive behavioral therapy, alone or in combination with total knee arthroplasty in patients with knee osteoarthritis – study protocol for the MultiKnee trial
(Journal article; Peer reviewed, 2021)Background One in five patients report chronic pain following total knee arthroplasty (TKA) and are considered non-improvers. Psychological interventions such as cognitive behavioral therapy (CBT), combined with exercise ... -
Iodine Nutrition and Iodine Supplement Initiation in Association with Thyroid Function in Mildly-to-Moderately Iodine-Deficient Pregnant and Postpartum Women
(Journal article; Peer reviewed, 2021)Background Whereas the adverse effects of severe iodine deficiency during pregnancy are well documented, the effects of mild-to-moderate deficiency are not well established. Objectives We aimed to explore whether ... -
General practitioners’ management of depression symptoms in Somali refugee and Norwegian patients: a film vignette experiment
(Journal article; Peer reviewed, 2021)Objectives Refugees in comparison with non-refugee patients may face higher unmet mental healthcare needs. The mechanisms underlying these disparities are still poorly understood. The general practitioner (GP) plays a vital ... -
Best Practice Recommendations for the Implementation of a Digital Pathology Workflow in the Anatomic Pathology Laboratory by the European Society of Digital and Integrative Pathology (ESDIP)
(Journal article; Peer reviewed, 2021)The interest in implementing digital pathology (DP) workflows to obtain whole slide image (WSI) files for diagnostic purposes has increased in the last few years. The increasing performance of technical components and the ... -
Characterization of Glycosylation-Specific Systemic and Mucosal IgA Antibody Responses to Escherichia coli Mucinase YghJ (SslE)
(Journal article; Peer reviewed, 2021)Efforts to develop broadly protective vaccines against pathogenic Escherichia coli are ongoing. A potential antigen candidate for vaccine development is the metalloprotease YghJ, or SslE. YghJ is a conserved mucinase that ...
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