Recent Submissions

  • Linking Nanomaterial-Induced Mitochondrial Dysfunction to Existing Adverse Outcome Pathways for Chemicals 

    Murugadoss, Sivakumar; Vrček, Ivana Vinković; Schaffert, Alexandra; Paparella, Martin; Pem, Barbara; Sosnowska, Anita; Stępnik, Maciej; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Cimpan, Mihaela-Roxana; Lemaire, Frauke; Mertens, Birgit; Dusinska, Maria; Fessard, Valérie; Hoet, Peter H. (Journal article; Peer reviewed, 2024)
    The Adverse Outcome Pathway (AOP) framework plays a crucial role in the paradigm shift of toxicity testing towards the development and use of new approach methodologies. AOPs developed for chemicals are in theory applicable ...
  • Prostate Biopsies Can Be Omitted in Most Patients with a Positive Stockholm3 Test and Negative Prostate Magnetic Resonance Imaging 

    Vinje, Cathrine Alvær; Vigmostad, Maria Nyre; Kjosavik, Svein Reidar; Grönberg, Henrik; Gilje, Bjørnar; Skeie, Svein (Journal article; Peer reviewed, 2024)
    Background Magnetic resonance imaging (MRI) combined with the Stockholm3 test can be used to inform biopsy decision-making in patients with a suspicion of prostate cancer. Objective To determine the consequence of ...
  • Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial 

    Halvorsen, Lene Vernås; Søraas, Camilla Lund; Larstorp, Anne Cecilie Kjeldsen; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Liestøl, Knut; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Bergland, Ola Undrum; Rognstad, Stine; Aarskog, Nikolai Ravn; Heimark, Sondre; Fadl Elmula, Fadl Elmula M.; Gerdts, Eva; Mo, Rune; Solbu, Marit Dahl; Opdal, Mimi Stokke; Kjeldsen, Sverre; Rostrup, Morten; Høieggen, Aud (Journal article; Peer reviewed, 2024)
    Background: Drug concentration in blood or urine is an acknowledged method to detect nonadherence. Observational studies suggest that informing patients about low or absent serum drug levels improves blood pressure (BP). ...
  • Long-Term Outcomes of Arthroscopically Verified Focal Cartilage Lesions in the Knee: A 19-Year Multicenter Follow-up with Patient-Reported Outcomes 

    Birkenes, Thomas; Furnes, Ove Nord; Lygre, Stein Håkon Låstad; Solheim, Eirik Johan; Årøen, Asbjørn; Knutsen, Gunnar; Drogset, Jon Olav; Heir, Stig; Engebretsen, Lars; Løken, Sverre Bertrand; Visnes, Håvard (Journal article; Peer reviewed, 2024)
    Background: Focal cartilage lesions (FCLs) are frequently found during knee arthroscopies and may impair quality of life (QoL) significantly. Several treatment options with good short-term results are available, but the ...
  • Breastfeeding and biomarkers of folate and cobalamin status in Norwegian infants: a cross-sectional study 

    Solvik, Beate Stokke; Bakken, Kjersti Sletten; McCann, Adrian; Ueland, Per Magne; Henjum, Sigrun; Strand, Tor Arne (Journal article; Peer reviewed, 2024)
    Folate and vitamin B12 (cobalamin) are essential for growth and development. This cross-sectional study aims to describe folate and vitamin B12 status according to infant age and breastfeeding practices in Norwegian infants. ...
  • On the hunt for metalloenzyme inhibitors: Investigating the presence of metal-coordinating compounds in screening libraries and chemical spaces 

    Schuck de Azevedo, Bruna; Brenk, Ruth (Journal article; Peer reviewed, 2024)
    Metalloenzymes play vital roles in various biological processes, requiring the search for inhibitors to develop treatment options for diverse diseases. While compound library screening is a conventional approach, the ...
  • Testing Maternal Effects of Vitamin-D and Omega-3 levels on Offspring Neurodevelopmental Traits in the Norwegian Mother, Father and Child Cohort Study 

    Wootton, Robyn E; Dack, Kyle; Jones, Hannah J; Riglin, Lucy; Madley-Dowd, Paul; Borges, Carolina; Pagoni, Panagiota; Roth, Christine; Brantsæter, Anne Lise; Corfield, Elizabeth Claire; Stoltenberg, Camilla; Øyen, Anne-Siri; Smith, George Davey; Ask, Helga; Thapar, Anita; Stergiakouli, Evie; Havdahl, Alexandra (Journal article; Peer reviewed, 2024)
    Background Maternal vitamin-D and omega-3 fatty acid (DHA) deficiencies during pregnancy have previously been associated with offspring neurodevelopmental traits. However, observational study designs cannot distinguish ...
  • Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16 

    Casey, Nicholas Paul; Kleinmanns, Katrin; Forcados, Christopher; Gelebart, Pascal Francois; Joaquina, Sandy; Lode, Martine Rott; Benard, Emmanuelle; Kaveh, Fatemeh; Caulier, Benjamin William; Gjerde, Christiane Helgestad; García de Jalón, Elvira; Warren, David; Lindemann, Kristina Yvonne Kathe; Rokkones, Erik; Davidson, Ben; Myhre, Marit; Kvalheim, Gunnar; Bjørge, Line; Mc Cormack, Emmet; Inderberg, Else Marit; Wälchli, Sébastien (Journal article; Peer reviewed, 2024)
    Background Ovarian cancer (OC) is the leading cause of death from gynecologic malignancies in the Western world. Contributing factors include a high frequency of late-stage diagnosis, the development of chemoresistance, ...
  • Long-term risk of arthroplasty and patient-reported outcomes following focal cartilage lesions in the knee 

    Birkenes, Thomas (Doctoral thesis, 2024-11-22)
    Bakgrunn: Fokale brusklesjoner er vanlige i kneet. Ingen av behandlingsmodaliteten for slike lesjoner er vist å være bedre enn andre. Få studier har rapportert den langsiktige prognosen, og risikoen for påfølgende ...
  • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021 

    Ferrari, Alize J; Santomauro, Damian Francesco; Aali, Amirali ; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; Abbastabar, Hedayat; ElHafeez, Samar Abd; Abdelmasseh, Michael ; Abd-Elsalam, Sherief ; Abdollahi, Arash; Abdullahi, Auwal; Kedir Hussein, Abegaz; Abeldaño Zuñiga, Roberto Ariel; Aboagye, Richard Gyan; Hassan, Abolhassani; Abreu, Lucas Guimarães; Abualruz, Hasan; Abu-Gharbieh, Eman; Abu-Rmeileh, Niveen ME; Ackerman, Ilana N; Addo, Isaac Yeboah; Addolorato, Giovanni; Adebiyi, Akindele Olupelumi; Adepoju, Abiola Victor; Omoponle Adewuyi, Habeeb; Afyouni, Shadi; Afzal, Saira ; Afzal, Sina; Agodi, Antonella ; Ahmad, Aqeel; Ahmad, Danish; Bjørge, Tone; Sagoe, Dominic; Eikemo, Terje Andreas; Steiner, Timothy J.; Kisa, Adnan; Kisa, Sezer; Wolf, Axel; Knudsen, Ann Kristin Skrindo; Vollset, Stein Emil; Zhou, Juexiao; Zhu, Zhaohua; Ziafati, Makan; Zielińska, Magdalena; Zimsen, Stephanie R M; Zoladl, Mohammad; Zumla, Alimuddin; Zyoud, Samer H.; Theo, Vos; Murray, Christopher JL (Journal article; Peer reviewed, 2024)
    Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury ...
  • Diet, Food, and Nutritional Exposures and Inflammatory Bowel Disease or Progression of Disease: an Umbrella Review 

    Christensen, Camilla; Knudsen, Andrea; Arnesen, Erik Kristoffer; Hatlebakk, Jan Gunnar; Sletten, Ida Sofie Karlsen; Fadnes, Lars T. (Journal article; Peer reviewed, 2024)
    Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), contributes to substantial morbidity. Understanding the intricate interplay between dietary factors and the incidence and ...
  • Kunnskapsoppsummering og klassifisering av tiltaket: Mestringskurs for ungdom (DU) ( 3 utg.) 

    Skotheim, Siv; Wergeland, Gro Janne Henningsen; Kvello, Øyvind (Journal article; Peer reviewed, 2024)
    Bakgrunn: Denne artikkelen er en kunnskapsoppsummering om effektene av Depresjonsmestring for ungdom (DU). Artikkelen er en revisjon av tidligere evalueringer av DU i Ungsinn (Wergeland, Skotheim & Kvello, 2016; Kvello, ...
  • Association between dietary macronutrient composition and plasma one-carbon metabolites and B-vitamin cofactors in patients with stable angina pectoris 

    Bråtveit, Marianne; Parys, Anthea van; Olsen, Thomas; Strand, Elin; Marienborg, Ingvild; Laupsa-Borge, Johnny; Haugsgjerd, Teresa Risan; McCann, Adrian; Dhar, Indu; Ueland, Per Magne; Dierkes, Jutta; Dankel, Simon Erling Nitter; Nygård, Ottar Kjell; Lysne, Vegard (Journal article; Peer reviewed, 2024)
    Elevated plasma concentrations of several one-carbon metabolites are associated with increased CVD risk. Both diet-induced regulation and dietary content of one-carbon metabolites can influence circulating concentrations ...
  • Use of primary healthcare services before and after specialized rehabilitation and its relation to changes in health and functioning: a longitudinal cohort study 

    Berget, Anne Mette Gravaas; Moen, Vegard Pihl; Hustoft, Merethe; Assmus, Jörg; Strand, Liv Inger; Skouen, Jan Sture; Hetlevik, Øystein (Journal article; Peer reviewed, 2024)
    Objective: To examine patients’ use of primary healthcare (PHC) before and after specialized rehabilitation and its relation with self-reported health and functioning. Design: Longitudinal cohort study. Participants: ...
  • Priority setting and migration health policies for European countries 

    Kumar, Bernadette. N; Bhopal, Anand; Blanchet, Karl; Wickramage, Kolitha; Onarheim, Kristine Husøy (Journal article; Peer reviewed, 2024)
    The 2030 Sustainable Development Goals (SDG) agenda has committed to ‘ensuring that no one is left behind’. Applying the right to health of non-citizens and international migrants is challenging in today's highly polarized ...
  • Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

    Naghavi, Mohsen; Ong, Kanyin Liane; Aali, Amirali; S Ababneh, Hazim S Ababneh; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana ; Abbasgholizadeh, Rouzbeh; Abbasian, Mohammadreza; Abbasi-Kangevari, Mohsen; Hedayat, Abbastabar; Abd ElHafeez, Samar; Abdelmasseh, Michael; Abd-Elsalam, Sherief; Abdelwahab, Ahmed Abdelwahab; Mohammad, Abdollahi; Abdollahifar, Mohammad-Amin; Abdoun, Meriem; Abdulah, Deldar Morad ; Abdullahi, Auwal; Abebe, Mesfin; Shawel Abebe, Samrawit; Aidin, Abedi; Kedir Hussein, Abegaz; Abhilash, E S ; Abidi, Hassan ; Abiodun, Olumide; Aboagye, Richard Gyan; Hassan, Abolhassani; Abolmaali, Meysam; Abouzid, Mohamed; Bjørge, Tone; Hailu, Alemayehu; Sagoe, Dominic; Wojewodzic, Marcin Wlodzimierz; Nauman, Javaid; Knudsen, Ann Kristin Skrindo; Madsen, Christian; Forthun, Ingeborg; Kisa, Adnan; Kisa, Sezer; Wolf, Axel; Eikemo, Terje Andreas; Vollset, Stein Emil; Zou, Zhiyong; Zuhlke, Liesl Joanna; Zumla, Alimuddin; Zweck, Elric; Zyoud, Samer H.; Wool, Eve E; Murray, Christopher J.L. (Journal article; Peer reviewed, 2024)
    Background: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy ...
  • Modeling geographic vaccination strategies for COVID-19 in Norway 

    Chan, Yat Hin; Rø, Gunnar; Midtbø, Jørgen E.; Di Ruscio, Francesco; Watle, Sara Sofie Viksmoen; Juvet, Lene Kristine; Littmann, Jasper; Aavitsland, Preben; Nygård, Karin Maria; Berg, Are Stuwitz; Bukholm, Geir; Kristoffersen, Anja Bråthen; Engø-Monsen, Kenth; Engebretsen, Solveig; Swanson, David Michael; Diz-Lois Palomares, Alfonso; Lindstrøm, Jonas Christoffer; Frigessi, Arnoldo; De Blasio, Birgitte Freiesleben (Journal article; Peer reviewed, 2024)
    Vaccination was a key intervention in controlling the COVID-19 pandemic globally. In early 2021, Norway faced significant regional variations in COVID-19 incidence and prevalence, with large differences in population ...
  • A Randomised, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial to Evaluate the Biological Effects and Safety of a Polyphenol Supplement on Healthy Ageing 

    Chong, Joyce Ruifen; De Lucia, Chiara; Tovar-Rios, Diego Alejandro; Castellanos Perilla, Nicolas; Collins, Christopher; Kvernberg, Silje Meihack; Ballard, Clive; Siow, Richard C.; Aarsland, Dag (Journal article; Peer reviewed, 2024)
    DailyColors™ is a supplement made up of several phytonutrients that aims to replicate elements from the Mediterranean diet. These include fruit, berry and vegetable extracts that are rich in key phytochemicals such as ...
  • Electronic Immunization Registry in Rwanda: Qualitative Study of Health Worker Experiences 

    Uwera, Thaoussi; Venkateswaran, Mahima; Bhutada, Kiran; Papadopoulou, Eleni; Rukundo, Enock; Tumusiime, David K.; Frøen, Jahn Frederik (Journal article; Peer reviewed, 2024)
    Background: Monitoring childhood immunization programs is essential for health systems. Despite the introduction of an electronic immunization registry called e-Tracker in Rwanda, challenges such as lacking population ...
  • Characterisation of global and regional mitral annular strains in an acute porcine model 

    Persson, Robert Matongo; Aguilera, Hans Martin Dahl; Grong, Ketil; Kvitting, John-Peder Escobar; Stangeland, Lodve; Haaverstad, Rune; Urheim, Stig; Prot, Victorien Emile (Journal article, 2024)
    OBJECTIVES This study aimed to explore regional mitral annular strain using a novel computational method. METHODS Eight pigs underwent implantation with piezoelectric transducers around the mitral annulus. Interventions ...

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