• Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study 

  Pettersen, Trond Røed; Schjøtt, Jan Didrik; Allore, Heather G; Bendz, Bjørn; Borregaard, Britt; Fridlund, Bengt Gotthard Anton; Larsen, Alf Inge; Nordrehaug, Jan Erik; Rotevatn, Svein; Wentzel-Larsen, Tore; Norekvål, Tone Merete (Journal article; Peer reviewed, 2022)

  Objective: To determine patient perceptions of generic medicines 2 and 6 months after percutaneous coronary intervention (PCI), and to determine whether these perceptions moderate medication adherence. Design: Prospective ...

• Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia 

  Bruserud, Øystein; Reikvam, Håkon; Brenner, Annette (Journal article; Peer reviewed, 2022-01-23)

  Toll-like receptor 4 (TLR4) is a pattern-recognizing receptor that can bind exogenous and endogenous ligands. It is expressed by acute myeloid leukemia (AML) cells, several bone marrow stromal cells, and nonleukemic cells ...

• Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension 

  Thorstensen, Christian W.; Clasen, Per-Erik; Rognstad, Stine; Haldsrud, Renate; Føreid, Siri; Helstrøm, Trine; Bergland, Ola Undrum; Halvorsen, Lene Vernås; Aune, Arleen; Olsen, Erik; Brobak, Karl Marius; Høieggen, Aud; Gustavsen, Ingebjørg G.; Larstorp, Anne Cecilie Kjeldsen; Søraas, Camilla Lund; Opdal, Mimi Stokke (Journal article; Peer reviewed, 2022)

  We developed three ultra-high pressure liquid chromatography coupled to mass spectrometry detection (UHPLC-MS/MS) methods to quantify 25 antihypertensive drugs in serum samples. Patient-reported drug lists were collected, ...

• The fecal microbiota transplantation response differs between patients with severe and moderate irritable bowel symptoms 

  El-Salhy, Magdy; Mazzawi, Tarek; Hausken, Trygve; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2022)

  Objectives: Fecal microbiota transplantation (FMT) is a promising intervention for patients with irritable bowel syndrome (IBS). The present study aimed to identify any differences in FMT response between patients with ...

• Mitokondriesykdom forårsaket av m.3243A>G-mutasjonen 

  Varhaug, Kristin Nielsen; Hikmat, Omar; Bindoff, Laurence Albert (Journal article; Peer reviewed, 2022)

  Mitokondriesykdom er blant de vanligste metabolske sykdommene og er relevant for mange medisinske spesialiteter. Denne kliniske oversiktsartikkelen omtaler en av de vanligste mutasjonene bak mitokondriesykdom: m.3243A>G. ...

• Safety and Clinical Efficacy of Mesenchymal Stem Cell Treatment in Traumatic Spinal Cord Injury, Multiple Sclerosis and Ischemic Stroke – A Systematic Review and Meta-Analysis 

  Kvistad, Christopher Elnan; Kråkenes, Torbjørn; Gjengedal, Gudveig Cecilie Gjerde; Mustafa, Kamal Babikeir Elnour; Rekand, Tiina; Bø, Lars (Journal article; Peer reviewed, 2022-05-30)

  Background: Mesenchymal stem cells (MSCs) is an attractive candidate in regenerative research and clinical trials have assessed their therapeutic potential in different neurological conditions with disparate etiologies. ...

• Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain 

  Bråten, Lars Christian Haugli; Grøvle, Lars; Wigemyr, Monica; Wilhelmsen, Maja; Gjefsen, Elisabeth; Espeland, Ansgar; Haugen, Anne Julsrud; Skouen, Jan Sture; Brox, Jens Ivar; Zwart, John Anker Henrik; Storheim, Kjersti; Ostelo, Raymond WJG.; Grotle, Margreth (Journal article; Peer reviewed, 2022)

  Objectives: The objective of this study was to estimate the minimal important change (MIC) and responsiveness of core patient reported outcome measures for chronic low back pain (LBP) and Modic changes. Study Design and ...

• Acute kidney injury in patients with COVID-19 in the intensive care unit: Evaluation of risk factors and mortality in a national cohort 

  Aukland, Eirik Aasen; Klepstad, Pål; Aukland, Stein Magnus; Zamanzad Ghavidel, Fatemeh; Buanes, Eirik Alnes (Journal article; Peer reviewed, 2022)

  Objectives: Acute kidney injury (AKI) is a frequent complication among critical ill patients with COVID-19, but the actual incidence is unknown as AKI-incidence varies from 25% to 89% in intensive care unit (ICU) populations. ...

• Etiske dilemmaer for sykehjemsleger under covid-19-pandemien 

  Mclean, Emily; Onarheim, Kristine Husøy; Schanche, Elisabeth; Schaufel, Margrethe Aase; Miljeteig, Ingrid (Journal article; Peer reviewed, 2022)

  Bakgrunn: Sykehjemsbeboere var ekstra sårbare for et alvorlig forløp av covid-19. Tidlig i pandemien ble det derfor bestemt at sykehjemmene måtte beskyttes gjennom tiltak som besøksforbud og testing- og isolasjonsregimer. ...

• European Society of Paediatric Radiology Artificial Intelligence taskforce: a new taskforce for the digital age 

  Laborie, Lene Bjerke; Naidoo, Jaishree; Pace, Erika; Ciet, Pierluigi; Eade, Christine; Wagner, Matthias W.; Huisman, Thierry A. G. M.; Shelmerdine, Susan C. (Journal article; Peer reviewed, 2022)

  A new task force dedicated to artificial intelligence (AI) with respect to paediatric radiology was created in 2021 at the International Paediatric Radiology (IPR) meeting in Rome, Italy (a joint society meeting by the ...

• Strong tuberculin response after BCG vaccination is associated with low multiple sclerosis risk: a population-based cohort study 

  Nakken, Ola; Holmøy, Trygve; Stigum, Hein; Myhr, Kjell-Morten; Dahl, Jesper; Heldal, Einar; Meyer, Haakon Eduard (Journal article; Peer reviewed, 2022)

  Background: Multiple sclerosis (MS) is characterized by inflammatory lesions in the central nervous system involving pro-inflammatory T-cells. Immune dysregulation is well described in prevalent disease, but it is not known ...

• Komplikasjoner etter kjevebrudd behandlet ved Haukeland universitetssjukehus 2015–2020 

  Kolberg, Hilde Mei; Antonipillai, Infanta; Løes, Sigbjørn; Pedersen, Torbjørn Østvik (Journal article; Peer reviewed, 2022)

  Kjevebrudd er en relativt vanlig skade særlig etter voldshendelser og fall. De fleste kjevebrudd krever operativ behandling. Denne studien belyser forekomsten av komplikasjoner etter behandling av kjevebrudd ved Haukeland ...

• Ureteroscopy for stone disease in the paediatric population: lessons learned and outcomes in a Nordic setting 

  Jones, Charles Patrick Warburton; Æsøy, Mathias S.; Gjengstø, Peder; Beisland, Christian; Ulvik, Øyvind (Journal article; Peer reviewed, 2022)

  Introduction: Paediatric stone disease is rare in the Nordic communities. Still, the condition can require surgical intervention in the form of ureteroscopy (URS). Here, we report outcomes achieved at a regional (tertiary) ...

• Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations 

  Rodriguez-Porcel, Federico; Wyman-Chick, Kathryn A.; Abdelnour Ruiz, Carla; Toledo, Jon B.; Ferreira, Daniel; Urwyler, Prabitha; Weil, Rimona S.; Kane, Joseph; Pilotto, Andrea; Rongve, Arvid; Boeve, Bradley; Taylor, John-Paul; McKeith, Ian; Aarsland, Dag; Lewis, Simon J. G. (Journal article; Peer reviewed, 2022)

  The selection of appropriate outcome measures is fundamental to the design of any successful clinical trial. Although dementia with Lewy bodies (DLB) is one of the most common neurodegenerative conditions, assessment of ...

• Safety of breast feeding during rituximab treatment in multiple sclerosis 

  Rød, Brit Ellen; Torkildsen, Øivind; Myhr, Kjell-Morten; Bø, Lars; Wergeland, Stig (Journal article; Peer reviewed, 2022)

  Background There are limited data on the safety of breast feeding during rituximab therapy. Our objective is to determine exposure from breast feeding and biological effects of rituximab in breastfed infants. Methods ...

• A novel age-related gene expression signature associates with proliferation and disease progression in breast cancer 

  Ingebriktsen, Lise Martine; Finne, Kenneth; Akslen, Lars Andreas; Wik, Elisabeth (Journal article; Peer reviewed, 2022)

  Background and objective Breast cancer (BC) diagnosed at ages <40 years presents with more aggressive tumour phenotypes and poorer clinical outcome compared to older BC patients. Here, we explored transcriptional BC ...

• “The Peer Educator Is the Game-Changer of My Life”: Perceptions of Adolescents Living with HIV in DR Congo on Involving Peer Educators in the Process of HIV Disclosure 

  Ndolumingu, Faustin Kitetele; Lelo, Gilbert M.; Akele, Cathy E.; Lelo, Patricia Vangu Matondo; Mafuta, Eric M.; Tylleskär, Thorkild; Kashala-Abotnes, Espérance (Journal article; Peer reviewed, 2022)

  Several approaches to the disclosure of HIV status to children and adolescents have been described. Each of these places particular emphasis on the role of parents and health care workers (HCWs) to mitigate the impact of ...

• Even chained acylcarnitines predict long-term cardiovascular prognosis in patients with chest pain and non-obstructive coronary artery disease 

  Storesund, Silje Kjellevold; Karaji, Iman; Strand, Elin; Svardal, Asbjørn M.; Lønnebakken, Mai Tone; Berge, Rolf Kristian; Svingen, Gard Frodahl Tveitevåg; Nygård, Ottar Kjell; Pedersen, Eva Ringdal (Journal article; Peer reviewed, 2022)

  Background Acylcarnitines are essential for mitochondrial fatty acid oxidation. Earlier studies suggest that impaired energy metabolism may be implicated in the pathogenesis of microvascular angina. We explored metabolites ...

• The prevalence and incidence of pharmacologically treated diabetes among older people receiving home care services in Norway 2009–2014: a nationwide longitudinal study 

  Teigland, Tonje; Igland, Jannicke; Tell, Grethe S.; Haltbakk, Johannes; Graue, Marit; Fismen, Anne-Siri; Birkeland, Kåre Inge; Østbye, Truls; Peyrot, Mark; Iversen, Marjolein M. (Journal article; Peer reviewed, 2022)

  Background A substantial proportion of older people who receive home care services (HCS) has diabetes and requires diabetes specific monitoring, treatment and self-care assistance. However, the prevalence and incidence ...

• Quantitative pupillometry in comatose out-of-hospital cardiac arrest patients: A post-hoc analysis of the TTH48 trial 

  Paramanathan, Sansuthan; Grejs, Anders Morten; Søreide, Eldar; Duez, Christophe Henri Valdemar; Jeppesen, Anni Nørgaard; Reinertsen, Åse Johanne; Strand, Kristian; Kirkegaard, Hans (Journal article; Peer reviewed, 2022)

  Background: Quantitative pupillometry is an objective method to examine pupil reaction and subsequently grade the response on a neurological pupil index (NPi) scale from 0 to 5. The aim of the present sub-study was to ...

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