Faculty of Medicine
Recent Submissions
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Genetic associations with psychosis and affective disturbance in Alzheimer's disease
(Journal article; Peer reviewed, 2024)Introduction: Individuals with Alzheimer's disease (AD) commonly experience neuropsychiatric symptoms of psychosis (AD+P) and/or affective disturbance (depression, anxiety, and/or irritability, AD+A). This study's goal was ... -
Prevalence, infant outcomes and gestational risk factors for transverse reduction deficiencies at or above the wrist: a population-based study
(Journal article; Peer reviewed, 2024)We identified individuals born in Norway between 1970 and 2019 with transverse reduction deficiency at or above the wrist (TRDAW) from the Medical Birth Registry of Norway and from the CULA (congenital upper limb anomaly) ... -
Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
(Journal article; Peer reviewed, 2024)Background Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely ... -
Small Cell Lung Cancer in Norway: Patterns of Care by Health Region and Survival Trends
(Journal article; Peer reviewed, 2024)Introduction/Background There has been a marked survival improvement for patients with non–small-cell lung cancer. We describe the national trends in characteristics and survival, and geographical differences in diagnostic ... -
Surface-Bioengineered Extracellular Vesicles Seeking Molecular Biotargets in Lung Cancer Cells
(Journal article; Peer reviewed, 2024)Personalized medicine is a new approach to modern oncology. Here, to facilitate the application of extracellular vesicles (EVs) derived from lung cancer cells as potent advanced therapy medicinal products in lung cancer, ... -
Factors affecting communication during telephone triage in medical call centres: a mixed methods systematic review
(Journal article; Peer reviewed, 2024-06-22)Background: Telephone triage is used to optimise patient flow in emergency primary healthcare. Poor communication can lead to misunderstandings and compromise patient safety. To improve quality, a comprehensive understanding ... -
DNA methylation risk score for type 2 diabetes is associated with gestational diabetes
(Journal article; Peer reviewed, 2024-02-13)Background: Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown. We aimed to test whether a ... -
Dialogue between researchers and older immigrant women in Norway after the COVID-19 pandemic. An exploration of their experience.
(Master thesis, 2024-08-23)Background: In the wake of the COVID-19 pandemic, marginalized groups, particularly older immigrant women, have faced exacerbated challenges, prompting an urgent need for research to understand their experiences after ... -
Sex-specific associations of kynurenic acid with neopterin in Alzheimer’s disease
(Journal article; Peer reviewed, 2024-07-27)Background: Sex differences in neuroinflammation could contribute to women’s increased risk of Alzheimer’s disease (AD), providing rationale for exploring sex-specific AD biomarkers. In AD, dysregulation of the kynurenine ... -
Neonatal Sepsis Episodes and Retinopathy of Prematurity in Very Preterm Infants
(Journal article; Peer reviewed, 2024)Importance: Retinopathy of prematurity (ROP) is a major morbidity of preterm infants causing visual impairment, including blindness, for which timely treatment is vital and prevention is key. Increasing evidence suggests ... -
Economic and social determinants of health care utilization during the first wave of COVID-19 pandemic among adults in Ghana: a population-based cross-sectional study
(Journal article; Peer reviewed, 2024-02-13)Background: The COVID-19 pandemic had socioeconomic effects in Africa. This study assessed the social and economic determinants of healthcare utilization during the first wave of COVID-19 among adults in Ghana. Methods: ... -
Divergent epigenetic responses to perinatal asphyxia in severe mental disorders
(Journal article; Peer reviewed, 2024)Epigenetic modifications influenced by environmental exposures are molecular sources of phenotypic heterogeneity found in schizophrenia and bipolar disorder and may contribute to shared etiopathogenetic mechanisms of these ... -
Impact of an integrated health, nutrition, and early child stimulation and responsive care intervention package delivered to preterm or term small for gestational age babies during infancy on growth and neurodevelopment: study protocol of an individually randomized controlled trial in India (Small Babies Trial)
(Journal article; Peer reviewed, 2024-02-08)Background: Preterm and term small for gestational age (SGA) babies are at high risk of experiencing malnutrition and impaired neurodevelopment. Standalone interventions have modest and sometimes inconsistent effects on ... -
Subsequent fracture risk in Norwegians and immigrants with an index forearm fracture: a cohort study
(Journal article; Peer reviewed, 2024)Summary: The current study investigated subsequent fracture risk following a forearm fracture in three country of birth categories: Norway, Europe and North America, and other countries. Subsequent fracture risk was modestly ... -
Dietary selenium and protein composition influence methylmercury toxicity in mice
(Doctoral thesis, 2024-11-15)Metylkvikksølv (MeHg) er en utberedt kontaminant i naturen som mennesker hovedsakelig blir eksponert for gjennom inntak av fisk. Samtidig inneholder fisk, og mat for øvrig, viktige næringsstoffer som kan påvirke MeHg-metabolisme ... -
Acupuncture for fatigue in breast cancer survivors: a study protocol for a pragmatic, mixed method, randomised controlled trial
(Journal article; Peer reviewed, 2024)Introduction: Fatigue is a common symptom observed in post-cancer treatment, yet its underlying mechanisms remain poorly understood. Acupuncture has been employed to alleviate cancer-related fatigue (CRF); however, its ... -
Occupational asthma in the salmon processing industry: a case series
(Journal article; Peer reviewed, 2024)Objectives: Exposure to bioaerosols in salmon processing workers is associated with occupational asthma. IgE-mediated allergy and other disease mechanisms may be involved in airway inflammation and obstruction. Knowledge ... -
Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
(Journal article; Peer reviewed, 2024)Background: The complement system, an upstream recognition system of innate immunity, is activated upon SARS-CoV-2 infection. To gain a deeper understanding of the extent and duration of this activation, we investigated ... -
Stable glioma incidence and increased patient survival over the past two decades in Norway: a nationwide registry-based cohort study
(Journal article; Peer reviewed, 2024)Background: Surveillance of incidence and survival of central nervous system tumors is essential to monitor disease burden and epidemiological changes, and to allocate health care resources. Here, we describe glioma incidence ... -
Severe isolated exudative vitreoretinopathy caused by biallelic FZD4 variants
(Journal article; Peer reviewed, 2024)Familial exudative vitreoretinopathy (FEVR) is linked to disruption of the Norrin/Frizzled-4 signaling pathway, which plays an important role in retinal angiogenesis. Severe or complete knock-down of proteins in the pathway ...