Faculty of Medicine
Nye registreringer
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Genetic epidemiology of amyotrophic lateral sclerosis in Norway - a 2-year population based study
(Journal article; Peer reviewed, 2022)Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects motor neurons. In Europe, disease-causing genetic variants have been identified in 40-70% of familial ALS patients and approximately ... -
Factors affecting fracture of zirconia dental crowns : Laboratory studies on retrievals and crown-shaped specimens
(Doctoral thesis, 2022-09-02)Objektiv: De siste 20 årene har bruken av zirkonia som dentalt materiale har økt betydelig. Laboratorietester som undersøker materialstyrke, indikerer at de tilgjengelige zirkonia-materialene har tilstrekkelige mekaniske ... -
Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement
(Journal article; Peer reviewed, 2022-01-07)Disability and distress caused by chronic low back pain (LBP) lacking clear pathoanatomical explanations cause huge problems both for patients and society. A subgroup of patients has Modic changes (MC), identifiable by MRI ... -
Trends in the prevalence of breastfeeding up to 6 months of age using structured data from routine child healthcare visits
(Journal article; Peer reviewed, 2022)Aim The Norwegian Action Plan for a Healthier Diet (2017–2021) set the target that 25% of infants should be exclusively breastfed for 6 months by 2022. Our aim was to determine trends in the prevalence and duration of ... -
Early Evolutionary Selection of NAD Biosynthesis Pathway in Bacteria
(Journal article; Peer reviewed, 2022)Bacteria use two alternative pathways to synthesize nicotinamide adenine dinucleotide (NAD) from nicotinamide (Nam). A short, two-step route proceeds through nicotinamide mononucleotide (NMN) formation, whereas the other ... -
Systematic reporting of medical kidney biopsies
(Journal article; Peer reviewed, 2022)The medical kidney biopsy has an important added value in patient care in nephrology. In order to facilitate communication between the pathologist and the nephrologist and optimize patient care, both the content and form ... -
Mitochondrial respiratory chain dysfunction—A hallmark pathology of idiopathic Parkinson’s disease?
(Journal article; Peer reviewed, 2022)Parkinson’s disease (PD) is the most common age-dependent neurodegenerative synucleinopathy. Loss of dopaminergic neurons of the substantia nigra pars compacta, together with region- and cell-specific aggregations of ... -
Trends in Mortality Due to Myocardial Infarction, Stroke, and Pulmonary Embolism in Patients Receiving Dialysis
(Journal article; Peer reviewed, 2022)Importance: During the past decades, improvements in the prevention and management of myocardial infarction, stroke, and pulmonary embolism have led to a decline in cardiovascular mortality in the general population. ... -
Association of adverse childhood experiences with the development of multiple sclerosis
(Journal article; Peer reviewed, 2022)Objective To study whether exposure to childhood emotional, sexual or physical abuse is associated with subsequent multiple sclerosis (MS) development. Methods A nationwide, prospective cohort study based on participants ... -
Changes in colonic enteroendocrine cells of patients with irritable bowel syndrome following fecal microbiota transplantation
(Journal article; Peer reviewed, 2022)Objectives The aim was to investigate the effect of fecal microbiota transplantation (FMT) on colonic enteroendocrine cells densities in patients with irritable bowel syndrome (IBS). Materials and methods This study ... -
Enhancement of cranial nerves in Lyme neuroborreliosis: incidence and correlation with clinical symptoms and prognosis
(Journal article; Peer reviewed, 2022)Purpose Symptoms of cranial neuritis are a common presentation of Lyme neuroborreliosis (LNB). Imaging studies are scarce and report contradictory low prevalence of enhancement compared to clinical studies of cranial ... -
Metric based virtual simulation training for endovascular thrombectomy improves interventional neuroradiologists’ simulator performance
(Journal article; Peer reviewed, 2022)Objective Metric based virtual reality simulation training may enhance the capability of interventional neuroradiologists (INR) to perform endovascular thrombectomy. As pilot for a national simulation study we examined ... -
Long-Term Outcome in a Phase II Study of Regional Hyperthermia Added to Preoperative Radiochemotherapy in Locally Advanced and Recurrent Rectal Adenocarcinomas
(Journal article; Peer reviewed, 2022-01-29)Hyperthermia was added to standard preoperative chemoradiation for rectal adenocarcinomas in a phase II study. Patients with T3-4 N0-2 M0 rectal cancer or local recurrences were included. Radiation dose was 54 Gy combined ... -
Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy
(Journal article; Peer reviewed, 2022)Background/objectives There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and ... -
Disease-Course Adapting Machine Learning Prognostication Models in Elderly Patients Critically Ill With COVID-19: Multicenter Cohort Study With External Validation
(Journal article; Peer reviewed, 2022)Background:The COVID-19 pandemic caused by SARS-CoV-2 is challenging health care systems globally. The disease disproportionately affects the elderly population, both in terms of disease severity and mortality risk. ... -
Identification of microRNAs from medicinal plant Murraya Koenigii by high-throughput sequencing and their functional implications in secondary metabolite biosynthesis
(Journal article; Peer reviewed, 2022)MicroRNAs (miRNAs) are small noncoding RNA molecules that play crucial post-transcriptional regulatory roles in plants, including development and stress-response signaling. However, information about their involvement in ... -
Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction
(Journal article; Peer reviewed, 2022)Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are ... -
In-office thermal systems for the treatment of dry eye disease
(Journal article; Peer reviewed, 2022)Dry eye disease affects millions of people worldwide, causing pain, vision disturbance, and reduced productivity. Meibomian gland dysfunction, a major cause of dry eye, is characterized by chronic glandular inflammation, ... -
Placental weight centiles adjusted for age, parity and fetal sex
(Journal article; Peer reviewed, 2022)Introduction The weight of the placenta can be indicative of efficacy in nutrient and oxygen supply. Furthermore, it has been suggested that a measure of the placenta's ability to adequately supply nutrients to the fetus ... -
Anti-PD-L1/TGF-βR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer
(Journal article, 2022)Background Second-generation programmed cell death-protein 1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors, such as bintrafusp alfa (M7824), SHR-1701, and YM101, have been developed to simultaneously block PD-1/PD-L1 ...
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