• The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial 

  Jakobsen, Gunnhild; Engstrøm, Morten; Hjermstad, Marianne Jensen; Rosland, Jan Henrik; Aass, Nina Kathrine; Albert, Eva; Kaasa, Stein; Fayers, Peter; Klepstad, Pål; Paulsen, Ørnulf (Journal article; Peer reviewed, 2020)

  Purpose: Although corticosteroids are frequently used in patients with advanced cancer, few studies have examined the impact of these drugs on patient-reported sleep. We aimed to examine the short-term impact of ...

• A Pilot Study of Circulating Monocyte Subsets in Patients Treated with Stem Cell Transplantation for High-Risk Hematological Malignancies. 

  Rundgren, Ida Marie; Ersvær, Elisabeth; Ahmed, Aymen B; Bruserud, Øystein; Ryningen, Anita (Journal article; Peer reviewed, 2020)

  Background and Objectives: Autologous and allogeneic stem cell transplantation is used in the treatment of high-risk hematological malignancies, and monocytes are probably involved in hematological reconstitution as well ...

• Near-Infrared Fluorescent Imaging for Monitoring of Treatment Response in Endometrial Carcinoma Patient-Derived Xenograft Models. 

  Fonnes, Tina; Strand, Elin; Fasmer, Kristine Eldevik; Berg, Hege Fredriksen; Espedal, Heidi; Sortland, Kristina; Stefansson, Ingunn; Bjørge, Line; Haldorsen, Ingfrid S; Krakstad, Camilla; Mc Cormack, Emmet (Journal article; Peer reviewed, 2020)

  Imaging of clinically relevant preclinical animal models is critical to the development of personalized therapeutic strategies for endometrial carcinoma. Although orthotopic patient-derived xenografts (PDXs) reflecting ...

• Environmental pollutants in blood donors: The multicentre Norwegian donor study 

  Averina, Maria; Hervig, Tor; Huber, Sandra; Kjær, Mette; Kristoffersen, Einar Klæboe; Bolann, Bjørn Johan (Journal article; Peer reviewed, 2020)

  Objectives The aim of this study was to measure blood concentrations of environmental pollutants in Norwegian donors and evaluate the risk of pollutant exposure through blood transfusions. Background Transfused blood ...

• Inspecting teams' and organisations' expectations regarding external inspections in health care: a qualitative study 

  Hovlid, Einar; Teig, Inger Lise; Halvorsen, Kjersti; Frich, Jan C (Journal article; Peer reviewed, 2020)

  Background There is a gap in the literature regarding what takes place between the announcement of a regulatory intervention, such as an external inspection of a health care organisation, and the inspecting body’s site ...

• Intrauterine growth restriction, preterm birth and risk of end-stage renal disease during the first 50 years of life 

  Gjerde, Anna; Lillås, Bjørn Steinar; Marti, Hans-Peter; Reisæter, Anna Varberg; Vikse, Bjørn Egil (Journal article; Peer reviewed, 2020)

  Background: Low birth weight (LBW) is associated with a higher risk of end-stage renal disease (ESRD). The relative impacts of absolute birth weight, birth weight in relation to gestational age and preterm birth are, ...

• Unsupervised clustering of missense variants in HNF1A using multidimensional functional data aids clinical interpretation 

  Althari, Sara; Najmi, Laeya Abdoli; Bennett, Amanda J.; Aukrust, Ingvild; Rundle, Jana K.; Colclough, Kevin; Molnes, Janne; Kaci, Alba; Nawaz, Sameena; van der Lugt, Timme; Hassanali, Neelam; Mahajan, Anubha; Molven, Anders; Ellard, Sian; McCarthy, Mark I.; Bjørkhaug, Lise; Njølstad, Pål Rasmus; Gloyn, Anna L. (Journal article; Peer reviewed, 2020-10-01)

  Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), ...

• Hip fracture treatment in Norway - deviation from evidence-based treatment guidelines: data from the Norwegian Hip Fracture Register, 2014 to 2018 

  Gjertsen, Jan Erik; Stensland, Eva; Byhring, Hanne Sigrun; Dybvik, Eva Hansen; Søreide, Odd; Kjærvik, Cato (Others, 2020)

  Aims The aim of this study was to describe variation in hip fracture treatment in Norway expressed as adherence to international and national evidence-based treatment guidelines, to study factors influencing deviation ...

• Global FKRP Registry: observations in more than 300 patients with Limb Girdle Muscular Dystrophy R9 

  Murphy, Lindsay B.; Schreiber-Katz, Olivia; Rafferty, Karen; Robertson, Agata; Topf, Ana; Willis, Tracey A.; Heidemann, Marcel; Thiele, Simone; Bindoff, Laurence; Laurent, Jean-Pierre; Lochmüller, Hanns; Mathews, Katherine; Mitchell, Claudia; Stevenson, John Herbert; Vissing, John; Woods, Lacey; Walter, Maggie C.; Straub, Volker (Journal article; Peer reviewed, 2020-04)

  Objective The Global FKRP Registry is a database for individuals with conditions caused by mutations in the Fukutin‐Related Protein (FKRP) gene: limb girdle muscular dystrophy R9 (LGMDR9, formerly LGMD2I) and congenital ...

• Parent-child communication about sexual issues in Zambia: a cross sectional study of adolescent girls and their parents 

  Isaksen, Katja; Musonda, Patrick; Sandøy, Ingvild Fossgard (Journal article; Peer reviewed, 2020)

  Background Parent-child communication about sexual issues can reduce risky sexual behaviour amongst adolescents. Risky sexual behaviour is of concern in sub-Saharan Africa where the prevalence of early pregnancy, unsafe ...

• A prospective study on cancer risk after total hip replacements for 41,402 patients linked to the Cancer registry of Norway 

  Dybvik, Eva Hansen; Furnes, Ove; Havelin, Leif Ivar; Fosså, Sophie Dorothea; Trovik, Clement; Lie, Stein Atle (Journal article; Peer reviewed, 2020)

  Background Concerns have been raised that implants used in total hip replacements (THR) could lead to increased cancer risk. Several different materials, metals and fixation techniques are used in joint prostheses and ...

• Movement quality evaluation and its correlation with recommended functional measures in hip osteoarthritis 

  Olsen, Aarid Liland; Magnussen, Liv Heide; Skjærven, Liv Karin Helvik; Assmus, Jörg; Sundal, Mary Anne; Ostelo, Raymond W.; Strand, Liv Inger (Journal article; Peer reviewed, 2020)

  Objective Hip osteoarthritis may cause compensational movement strategies that require extra physical and mental effort. Such aberrant functioning can be captured in movement quality evaluation. The objective of this study ...

• Exploring the genetic contribution to idiopathic Parkinson disease 

  Gaare, Johannes Jernqvist (Doctoral thesis, 2021-03-05)

  Background: Parkinson disease (PD) is a major cause of death and disability and has a devastating global socioeconomic impact. It affects 1-2% of the population above the age of 65 and its prevalence increases as the ...

• "If I have money, I cannot allow my baby to breastfeed only …" barriers and facilitators to scale-up of peer counselling for exclusive breastfeeding in Uganda 

  Rujumba, Joseph; Ndeezi, Grace; Nankabirwa, Victoria; Kwagala, Mary; Mukochi, Michelle; Diallo, Abdoulaye Hama; Meda, Nicolas; Engebretsen, Ingunn Marie S.; Tylleskär, Thorkild; Tumwine, James K (Journal article; Peer reviewed, 2020-05-15)

  Background Early initiation and exclusive breastfeeding for 6 months reduces infant morbidity and mortality and can positively impact on cognitive function. In Uganda, exclusive breastfeeding for 6 months is recommended ...

• Fluid transport from the dental pulp revisited. 

  Berggreen, Ellen; Wiig, Helge; Virtej, Anca (Journal article; Peer reviewed, 2020-10)

  In the dental pulp surrounded by rigid dentinal walls, an increase in fluid volume will be followed by a rapid increase in interstitial fluid pressure. To maintain pressure homeostasis, a fluid drainage system is required. ...

• Revealing and Harnessing Tumour-Associated Microglia/Macrophage Heterogeneity in Glioblastoma 

  Pires-Afonso, Yolanda; Niclou, Simone Pierrette; Michelucci, Alessandro (Journal article; Peer reviewed, 2020)

  Cancer heterogeneity and progression are subject to complex interactions between neoplastic cells and their microenvironment, including the immune system. Although glioblastomas (GBMs) are classified as ‘cold tumours’ with ...

• The Association Between Shift Work and Immunological Biomarkers in Nurses 

  Bjorvatn, Bjørn; Axelsson, John; Pallesen, Ståle; Waage, Siri; Vedaa, Øystein; Blytt, Kjersti Marie; Buchvold, Hogne Vikanes; Moen, Bente Elisabeth; Thun, Eirunn (Journal article; Peer reviewed, 2020)

  Objectives: Shift work is associated with several negative health effects. The underlying pathophysiological mechanisms are unclear, but low-grade inflammation has been suggested to play a role. This project aimed to ...

• Exclusive breastfeeding among HIV exposed infants from birth to 14 weeks of life in Lira, Northern Uganda: a prospective cohort study 

  Napyo, Agnes Kasede; Tumwine, James K.; Mukunya, David; Waako, Paul; Tylleskär, Thorkild; Ndeezi, Grace (Journal article; Peer reviewed, 2020)

  Background Breastfeeding is important for growth, development and survival of HIV exposed infants. Exclusive breastfeeding reduces the risk of morbidity, mortality and increases HIV free survival of infants. Evidence on ...

• Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci 

  Gaare, Johannes Jernqvist; Sanchez Nido, Gonzalo; Dölle, Christian; Sztromwasser, Pawel Szymon; Alves, Guido Werner; Tysnes, Ole-Bjørn; Haugarvoll, Kristoffer; Tzoulis, Charalampos (Journal article; Peer reviewed, 2020-10-01)

  Parkinson disease (PD) is a complex neurodegenerative disorder influenced by both environmental and genetic factors. While genome wide association studies have identified several susceptibility loci, many causal variants ...

• The power of empirical data; lessons from the clinical registry initiatives in Scandinavian cancer care 

  Nilbert, Mef; Thomsen, Linda Aagaard; Winther Jensen, Jens; Møller, Henrik; Borre, Michael; Widenlou Nordmark, Arvid; Lambe, Mats; Brändström, Helena; Kørner, Hartwig; Møller, Bjørn; Ursin, Giske (Journal article; Peer reviewed, 2020)

  Background In Scandinavia, there is a strong tradition for research and quality monitoring based on registry data. In Denmark, Norway and Sweden, 63 clinical registries collect data on disease characteristics, treatment ...

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