Faculty of Medicine
Recent Submissions
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Long-term risk of arthroplasty and patient-reported outcomes following focal cartilage lesions in the knee
(Doctoral thesis, 2024-11-22)Bakgrunn: Fokale brusklesjoner er vanlige i kneet. Ingen av behandlingsmodaliteten for slike lesjoner er vist å være bedre enn andre. Få studier har rapportert den langsiktige prognosen, og risikoen for påfølgende ... -
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
(Journal article; Peer reviewed, 2024)Background Ovarian cancer (OC) is the leading cause of death from gynecologic malignancies in the Western world. Contributing factors include a high frequency of late-stage diagnosis, the development of chemoresistance, ... -
Testing Maternal Effects of Vitamin-D and Omega-3 levels on Offspring Neurodevelopmental Traits in the Norwegian Mother, Father and Child Cohort Study
(Journal article; Peer reviewed, 2024)Background Maternal vitamin-D and omega-3 fatty acid (DHA) deficiencies during pregnancy have previously been associated with offspring neurodevelopmental traits. However, observational study designs cannot distinguish ... -
Effect of Therapeutic Drug Monitoring on Adherence and Blood Pressure: A Multicenter Randomized Clinical Trial
(Journal article; Peer reviewed, 2024)Background: Drug concentration in blood or urine is an acknowledged method to detect nonadherence. Observational studies suggest that informing patients about low or absent serum drug levels improves blood pressure (BP). ... -
On the hunt for metalloenzyme inhibitors: Investigating the presence of metal-coordinating compounds in screening libraries and chemical spaces
(Journal article; Peer reviewed, 2024)Metalloenzymes play vital roles in various biological processes, requiring the search for inhibitors to develop treatment options for diverse diseases. While compound library screening is a conventional approach, the ... -
Long-Term Outcomes of Arthroscopically Verified Focal Cartilage Lesions in the Knee: A 19-Year Multicenter Follow-up with Patient-Reported Outcomes
(Journal article; Peer reviewed, 2024)Background: Focal cartilage lesions (FCLs) are frequently found during knee arthroscopies and may impair quality of life (QoL) significantly. Several treatment options with good short-term results are available, but the ... -
Breastfeeding and biomarkers of folate and cobalamin status in Norwegian infants: a cross-sectional study
(Journal article; Peer reviewed, 2024)Folate and vitamin B12 (cobalamin) are essential for growth and development. This cross-sectional study aims to describe folate and vitamin B12 status according to infant age and breastfeeding practices in Norwegian infants. ... -
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021
(Journal article; Peer reviewed, 2024)Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury ... -
Diet, Food, and Nutritional Exposures and Inflammatory Bowel Disease or Progression of Disease: an Umbrella Review
(Journal article; Peer reviewed, 2024)Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), contributes to substantial morbidity. Understanding the intricate interplay between dietary factors and the incidence and ... -
Kunnskapsoppsummering og klassifisering av tiltaket: Mestringskurs for ungdom (DU) ( 3 utg.)
(Journal article; Peer reviewed, 2024)Bakgrunn: Denne artikkelen er en kunnskapsoppsummering om effektene av Depresjonsmestring for ungdom (DU). Artikkelen er en revisjon av tidligere evalueringer av DU i Ungsinn (Wergeland, Skotheim & Kvello, 2016; Kvello, ... -
Association between dietary macronutrient composition and plasma one-carbon metabolites and B-vitamin cofactors in patients with stable angina pectoris
(Journal article; Peer reviewed, 2024)Elevated plasma concentrations of several one-carbon metabolites are associated with increased CVD risk. Both diet-induced regulation and dietary content of one-carbon metabolites can influence circulating concentrations ... -
Use of primary healthcare services before and after specialized rehabilitation and its relation to changes in health and functioning: a longitudinal cohort study
(Journal article; Peer reviewed, 2024)Objective: To examine patients’ use of primary healthcare (PHC) before and after specialized rehabilitation and its relation with self-reported health and functioning. Design: Longitudinal cohort study. Participants: ... -
Priority setting and migration health policies for European countries
(Journal article; Peer reviewed, 2024)The 2030 Sustainable Development Goals (SDG) agenda has committed to ‘ensuring that no one is left behind’. Applying the right to health of non-citizens and international migrants is challenging in today's highly polarized ... -
Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
(Journal article; Peer reviewed, 2024)Background: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy ... -
Modeling geographic vaccination strategies for COVID-19 in Norway
(Journal article; Peer reviewed, 2024)Vaccination was a key intervention in controlling the COVID-19 pandemic globally. In early 2021, Norway faced significant regional variations in COVID-19 incidence and prevalence, with large differences in population ... -
A Randomised, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial to Evaluate the Biological Effects and Safety of a Polyphenol Supplement on Healthy Ageing
(Journal article; Peer reviewed, 2024)DailyColors™ is a supplement made up of several phytonutrients that aims to replicate elements from the Mediterranean diet. These include fruit, berry and vegetable extracts that are rich in key phytochemicals such as ... -
Electronic Immunization Registry in Rwanda: Qualitative Study of Health Worker Experiences
(Journal article; Peer reviewed, 2024)Background: Monitoring childhood immunization programs is essential for health systems. Despite the introduction of an electronic immunization registry called e-Tracker in Rwanda, challenges such as lacking population ... -
Characterisation of global and regional mitral annular strains in an acute porcine model
(Journal article, 2024)OBJECTIVES This study aimed to explore regional mitral annular strain using a novel computational method. METHODS Eight pigs underwent implantation with piezoelectric transducers around the mitral annulus. Interventions ... -
Extracellular matrix remodelling pathway in peripheral blood mononuclear cells from severe COVID-19 patients: an explorative study
(Journal article; Peer reviewed, 2024)There is a reciprocal relationship between extracellular matrix (ECM) remodelling and inflammation that could be operating in the progression of severe COVID-19. To explore the immune-driven ECM remodelling in COVID-19, ... -
Sex differences in left atrial volumes, mechanics, and stiffness in primary mitral regurgitation - a combined 2D and 3D echocardiographic study
(Journal article; Peer reviewed, 2024)Aims Mitral regurgitation (MR) causes left atrial (LA) enlargement and impaired reservoir function. We assessed whether changes in LA size, strain, and stiffness in significant (moderate or greater) primary MR are ...