Recent Submissions

  • European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation 

    Budu-Aggrey, Ashley; Kilanowski, Anna; Sobczyk, Maria K.; Shringarpure, Suyash S.; Mitchell, Ruth; Reis, Kadri; Reigo, Anu; Mägi, Reedik; Nelis, Mari; Tanaka, Nao; Brumpton, Ben Michael; Thomas, Laurent Francois; Sole-Navais, Pol; Flatley, Christopher; Espuela-Ortiz, Antonio; Herrera-Luis, Esther; Lominchar, Jesus V. T.; Bork-Jensen, Jette; Marenholz, Ingo; Arnau-Soler, Aleix; Jeong, Ayoung; Fawcett, Katherine A.; Baurecht, Hansjorg; Rodriguez, Elke; Alves, Alexessander Couto; Kumar, Ashish; Sleiman, Patrick M.; Chang, Xiao; Medina-Gomez, Carolina; Hu, Chen; Xu, Cheng-jian; Qi, Cancan; El-Heis, Sarah; Titcombe, Philip; Antoun, Elie; Fadista, João; Wang, Carol A.; Thiering, Elisabeth; Wu, Baojun; Kress, Sara; Kothalawala, Dilini M.; Kadalayil, Latha; Duan, Jiasong; Zhang, Hongmei; Hadebe, Sabelo; Hoffmann, Thomas; Jorgenson, Eric; Choquet, Hélène; Risch, Neil; Njølstad, Pål Rasmus; Andreassen, Ole; Johansson, Stefan; Almqvist, Catarina; Gong, Tong; Ullemar, Vilhelmina; Karlsson, Robert; Magnusson, Patrik K. E.; Szwajda, Agnieszka; Burchard, Esteban G.; Thyssen, Jacob P.; Hansen, Torben; Kårhus, Line L.; Dantoft, Thomas M.; Jeanrenaud, Alexander C.S.N.; Ghauri, Ahla; Arnold, Andreas; Homuth, Georg; Lau, Susanne; Nöthen, Markus M.; Hübner, Norbert; Imboden, Medea; Visconti, Alessia; Falchi, Mario; Bataille, Veronique; Hysi, Pirro; Ballardini, Natalia; Boomsma, Dorret I.; Hottenga, Jouke J.; Müller-Nurasyid, Martina; Ahluwalia, Tarunveer S.; Stokholm, Jakob; Chawes, Bo; Schoos, Ann-Marie M.; Esplugues, Ana; Bustamante, Mariona; Raby, Benjamin; Arshad, Syed; German, Chris; Esko, Tõnu; Milani, Lili A.; Metspalu, Andres; Terao, Chikashi; Abuabara, Katrina; Løset, Mari; Hveem, Kristian; Jacobsson, Bo; Pino-Yanes, Maria; Strachan, David P.; Grarup, Niels; Linneberg, Allan; Lee, Young-Ae; Probst-Hensch, Nicole; Weidinger, Stephan; Jarvelin, Marjo-Riitta; Melén, Erik; Hakonarson, Hakon; Irvine, Alan D.; Jarvis, Deborah; Nijsten, Tamar; Duijts, Liesbeth; Vonk, Judith M.; Koppelmann, Gerard H.; Godfrey, Keith M.; Barton, Sheila J.; Feenstra, Bjarke; Pennell, Craig E.; Sly, Peter D.; Holt, Patrick G.; Williams, L. Keoki; Bisgaard, Hans; Bønnelykke, Klaus; Curtin, John; Simpson, Angela; Murray, Clare; Schikowski, Tamara; Bunyavanich, Supinda; Weiss, Scott T.; Holloway, John W.; Min, Josine L.; Brown, Sara J.; Standl, Marie; Paternoster, Lavinia (Journal article; Peer reviewed, 2023)
    Atopic dermatitis (AD) is a common inflammatory skin condition and prior genome-wide association studies (GWAS) have identified 71 associated loci. In the current study we conducted the largest AD GWAS to date (discovery ...
  • The surveillance of patients hospitalised with COVID-19 in Norway, February 2020 – May 2022 : Systems comparisons, risk factors and clinical course 

    Whittaker, Robert Neil (Doctoral thesis, 2024-04-26)
    Bakgrunn: I Norge ble tre ulike system for overvåking av pasienter innlagt i sykehus med COVID-19 opprettet for å overvåke alvorligheten av pandemien. Ett var en aggregert, manuell innrapportering om belegg ved sykehusene, ...
  • Novel Insights into the Pathogenesis of Human Post-Primary Tuberculosis from Archival Material of the Pre-Antibiotic Era, 1931–1947 

    Riaz, Syeda Mariam; Hanevik, Kurt; Helgeland, Lars; Sviland, Lisbet; Hunter, Robert L.; Mustafa, Tehmina (Journal article; Peer reviewed, 2023)
    Objectives: Primary and post-primary tuberculosis (TB) are distinct entities. The aim of this study was to study the histopathology of primary and post-primary TB by using the unique human autopsy material from the ...
  • Evaluation of an interprofessional follow-up intervention among people with type 2 diabetes in primary care—A randomized controlled trial with embedded qualitative interviews 

    Graue, Marit; Igland, Jannicke; Haugstvedt, Anne; Hernar, Ingvild; Birkeland, Kåre Inge; Zoffmann, Vibeke; Richards, David A; Kolltveit, Beate-Christin Hope (Journal article; Peer reviewed, 2023)
    With an ageing population and improved treatments people live longer with their chronic diseases, and primary care clinics face more costly and difficult-to-treat multimorbid patients. To meet these challenges, current ...
  • Cardiac rehabilitation participation within 6 months of discharge in 37 136 myocardial infarction survivors: a nationwide registry study 

    Norekvål, Tone Merete; Bale, Marte; Bedane, Haji Kedir; Hole, Torstein Laurits; Ingul, Charlotte Ingeborg Björk; Munkhaugen, John (Journal article; Peer reviewed, 2023)
  • Real-world data on niraparib maintenance treatment in patients with non-gBRCA mutated platinum-sensitive recurrent ovarian cancer 

    Elgaaen, Bente Vilming; Dahl, Jørgen Fallås; Bentzen, Anne Gry; Ingebrigtsen, Vibeke Anett; Nilsen, Elisabeth Berge; Vistad, Ingvild; Dørum, Anne; Popova, Olesya; Bjørge, Line; Zucknick, Manuela; Aune, Guro; Lindemann, Kristina Yvonne Kathe (Journal article; Peer reviewed, 2023)
    Objectives The aim of this study was to provide real-world efficacy and safety data on niraparib maintenance treatment in patients with non-germline (gBRCA)1/2 mutated platinum-sensitive recurrent ovarian cancer. Methods ...
  • Unveiling sex bias and adverse neonatal outcomes in ultrasound estimation of gestational age: A population-based cohort study 

    Einum, Anders; Sørbye, Linn Marie; Nilsen, Roy Miodini; Ebbing, Cathrine; Morken, Nils-Halvdan (Journal article; Peer reviewed, 2024)
    Background Gestational age estimation by second-trimester ultrasound biometry introduces systematic errors due to sex differences in early foetal growth, consequently increasing the risk of adverse neonatal outcomes. ...
  • Effect of sense of coherence on long-term work participation among rehabilitation patients: A longitudinal study 

    Berget, Anne Mette Gravaas; Moen, Vegard Pihl; Hustoft, Merethe; Assmus, Jörg; Strand, Liv Inger; Skouen, Jan Sture; Hetlevik, Øystein (Journal article; Peer reviewed, 2023)
    Objective: To investigate the causal effect of sense of coherence on long-term work participation after rehabilitation, including stratification by age and diagnoses. Design: Longitudinal cohort study. Participants: ...
  • The impact of placental genomic risk for schizophrenia and birth asphyxia on brain development 

    Wortinger, Laura Anne; Shadrin, Alexey; Szabo, Attila; Nerland, Stener; Smelror, Runar; Jørgensen, Kjetil Nordbø; Barth, Claudia; Andreou, Dimitrios; Thoresen, Marianne; Andreassen, Ole; Djurovic, Srdjan; Ursini, Gianluca; Agartz, Ingrid (Journal article; Peer reviewed, 2023)
    The placenta plays a role in fetal brain development, and pregnancy and birth complications can be signs of placental dysfunction. Birth asphyxia is associated with smaller head size and higher risk of developing schizophrenia ...
  • Benzene exposure and risk of lung cancer in the Norwegian Offshore Petroleum Worker cohort: a prospective case-cohort study 

    Babigumira, Ronnie; Veierød, Marit Bragelien; Hosgood, H. Dean; Samuelsen, Sven Ove; Bråtveit, Magne; Kirkeleit, Jorunn; Rothman, Nathaniel; Lan, Qing; Silverman, Debra T.; Friesen, Melissa C.; Shala, Nita Kaupang; Grimsrud, Tom Kristian; Stenehjem, Jo Steinson (Journal article; Peer reviewed, 2024)
    Objective The objective of our study was to examine whether occupational exposure to benzene is associated with lung cancer among males in the Norwegian Offshore Petroleum Workers cohort. Methods Among 25 347 male offshore ...
  • SARS-CoV-2 specific immune responses in overweight and obese COVID-19 patients 

    Onyango, Therese Bredholt; Zhou, Fan; Bredholt, Geir; Brokstad, Karl Albert; Jalloh, Sarah Larteley Lartey; Mohn, Kristin Greve-Isdahl; Özgümüs, Türküler; Kittang, Bård Reiakvam; Linchausen, Dagrun Waag; Shafiani, Shahin; Elyanow, Rebecca; Blomberg, Bjørn; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2023)
    Obesity is a known risk factor for severe respiratory tract infections. In this prospective study, we assessed the impact of being obese or overweight on longitudinal SARS-CoV-2 humoral and cellular responses up to 18 ...
  • Targeted proteomics in a population-based study identifies serum PECAM-1 and TRIM21 as inflammation markers for periodontitis 

    Reckelkamm, Stefan Lars; Kaminska, Inga; Baumeister, Sebastian-Edgar; Ponce-de-Leon, Mariana; Ehmke, Benjamin; Rodakowska, Ewa; Baginska, Joanna; Nolde, Michael; Kaminski, Karol Adam (Journal article; Peer reviewed, 2023)
    Objectives Periodontitis (PD) can cause systematic inflammation and is associated with various metabolic processes in the body. However, robust serum markers for these relationships are still lacking. This study aims ...
  • Microvascular proliferation is associated with high tumour blood flow by mpMRI and disease progression in primary prostate cancer 

    Børretzen, Astrid; Reisæter, Lars Anders Rokne; Ringheim, Anders; Gravdal, Karsten; Haukaas, Svein Andreas; Fasmer, Kristine Eldevik; Haldorsen, Ingfrid S.; Beisland, Christian; Akslen, Lars Andreas; Halvorsen, Ole Johan (Journal article; Peer reviewed, 2023)
    Active angiogenesis may be assessed by immunohistochemistry using Nestin, a marker of newly formed vessels, combined with Ki67 for proliferating cells. Here, we studied microvascular proliferation by Nestin-Ki67 co-expression ...
  • A new pathway for penicillin delabeling in Norway 

    Alnæs, Marie Bjørbak; Oppegaard, Oddvar; Kittang, Bård Reiakvam; Lygre, Stein Håkon Låstad; Langeland, Anine Bernhoft; Skodvin, Brita; Bjånes, Tormod Karlsen; Storaas, Torgeir (Journal article; Peer reviewed, 2023)
    Background: Penicillin allergy is self-reported by 3–10% of patients admitted to hospital. The label is wrong in 90% of the cases and has severe health implications. Penicillin-delabeling can reverse the negative effects ...
  • TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma 

    Dongre, Harsh Nitin; Elnour, Rammah; Tornaas, Stian; Fromreide, Siren; Thomsen, Liv Cecilie Vestrheim; Kolseth, Ingrid Moss; Nginamau, Elisabeth Sivy; Johannessen, Anne Christine; Vintermyr, Olav Karsten; Costea, Daniela Elena; Bjørge, Line (Journal article; Peer reviewed, 2024)
    Introduction: Vulva squamous cell carcinoma (VSCC) develops through two separate molecular pathways—one involving high-risk human papilloma virus infection (HPV-associated), and the other without HPV infection (HPV-independent) ...
  • Å lære av feil: en kvalitativ studie av læringsmøter ved en psykiatrisk klinikk 

    Loftesnes, Urd Hege (Master thesis, 2023-10-24)
    Kvalitativ studie av hvordan innføring av faste læringsmøter påvirker deltakernes kommunikasjon, samhandling og håndtering av risiko. Studien gir innsikt i hvordan innføring av læringsmøter påvirker ansatte ved psykiatriske ...
  • Feedback System Analysis of a Multicomponent Intervention on Dyads of Home-Dwelling Persons With Dementia and Their Caregivers: Results From the LIVE@ Home.Path Trial 

    Vislapuu, Maarja; Patrascu, Monica; Allore, Heather; Husebø, Bettina; Kjerstad, Egil; Gedde, Marie H.; Berge, Line Iden (Journal article; Peer reviewed, 2024)
    Background and Objectives: Proper symptom management, informal caregiver support, and service innovation are required to reduce dementia care burden. The objective of this study is to investigate the effect of the ...
  • Characterization of Melanoma Brain Metastasis Cell Lines 

    Bjørnstad, Ole Vidhammer (Master thesis, 2019-06-03)
    Brain metastasis is a major public health problem. Metastatic brain tumors are ten times more common than that of all other primary brain tumors combined. The estimated annual incidence in Europe is around 1.5 million cases ...
  • Orthopaedic surgeons' ability to detect pathologic hip fractures: review of 1484 fractures reported to the Norwegian Hip Fracture Register 

    Sund, Anders; Dybvik, Eva Hansen; Gjertsen, Jan-Erik (Journal article; Peer reviewed, 2023-11-04)
    Background: The proximal femur is the most common location of metastases in the appendicular skeleton. Data on pathologic hip fractures, however, are sparse despite it is the most frequently operated pathologic fracture. ...
  • Cognitive assessment in the early stages of multiple sclerosis : the importance of screening and management of cognitive impairment 

    Skorve, Ellen Danielsen (Doctoral thesis, 2024-04-19)
    Bakgrunn: Kognitiv svekkelse er et vanlig symptom hos pasienter med multippel sklerose (MS), med potentielt stor innvirkning på livskvalitet, yrkesdeltagelse og sosialt liv. Dette kan oppstå i alle stadier og alle subtyper ...

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