• Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison's Disease 

  Sævik, Åse Bjorvatn; Wolff, Anette Susanne Bøe; Björnsdottir, Sigridur; Simunkova, Katerina; Hynne, Martha Schei; Dolan, David William Peter; Bratland, Eirik; Knappskog, Per M; Methlie, Paal; Carlsen, Siri; Isaksson, Magnus; Bensing, Sophie; Kämpe, Olof; Husebye, Eystein S; Løvås, Kristian; Øksnes, Marianne (Journal article; Peer reviewed, 2021)

  Background No reliable biomarkers exist to guide glucocorticoid (GC) replacement treatment in autoimmune Addison’s disease (AAD), leading to overtreatment with alarming and persistent side effects or undertreatment, which ...

• Sex-Specific Limitations in Physical Health in Primary Adrenal Insufficiency 

  Didriksen, Nora Møller; Sævik, Åse Bjorvatn; Sortland, Linn Solveig; Øksnes, Marianne; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2021)

  Background: Patients with primary adrenal insufficiency (PAI) suffer reduced quality of life (QoL), but comparisons with large-scale normative data are scarce. The clinical characteristics associated with reduced QoL are ...

• Health and Healthcare Access and Utilization Among Syrian Refugees Migrating to Norway : A Longitudinal Study 

  Haj Younes, Jasmin (Doctoral thesis, 2022-01-26)

  Background: An unprecedented number of people are on the move today and the health of refugees has become a vital global public health concern. During the migration process, refugees move from one environment to another ...

• In vitro kvalitet og hemostatisk funksjon i kaldlagret CPDA-1 fullblod etter gjentatte temperatursvingninger til 28 °C 

  Sivertsen, Joar (Master thesis, 2021-11-15)

  Bakgrunn: Blodprodukter blir ofte utsatt for romtemperatur eller høyere i lengre perioder enn tillatt av retningslinjer. Jeg undersøkte om dette førte til målbar effekt på mye brukte kvalitetsparametere og viskoelastisk ...

• Etiske utfordringer i sykehjem under Covid-19 pandemien -pleiepersonells erfaringer 

  Fammestad, Marie Constance (Master thesis, 2021-11-15)

  Covid-19 pandemien fikk store konsekvenser for pasienter og ansatte i sykehjem. Hensikten med denne studien er å etablere kunnskap om de etiske utfordringene ansatte i sykehjem erfarte under Covid-19 pandemien i 2020/21 ...

• Role of Adipocyte SLC7A10 and Amino Acid Metabolism in Obesity and Insulin Resistance 

  Jersin, Regine Åsen (Doctoral thesis, 2020-12-18)

  Obesity is a rising global concern, associated with increased risk of developing metabolic syndrome, insulin resistance and type 2 diabetes. Chronic availability of excess nutrients may promote adipocyte dysfunction, ...

• Use of quantitative pathology to improve grading and predict prognosis in tumours of the gastrointestinal tract 

  Lea, Dordi (Doctoral thesis, 2022-01-14)

  Cancer represents a formidable health burden and was the second leading cause of death globally in 2018. In Norway, almost 35000 new cancer cases were reported in 2019. For colon cancer, the incidence and mortality rates ...

• Work and health in the coir industry in Sri Lanka: a descriptive study with a specific focus on risk factors for injuries and incidence of injuries at these workplaces 

  Onni, Anindita Tasnim (Master thesis, 2021-11-23)

  Abstract Introduction The coir industry processes fibres from coconuts. This industry plays an important role in sustaining the livelihood of a large number of people in Sri Lanka. Coir-related exports account for 6% of ...

• Phosphatidylserine receptors enhance SARS-CoV-2 infection 

  Bohan, Dana; Van Ert, Hanora; Ruggio, Natalie; Rogers, Kai J; Badreddine, Mohammad; Aguilar Briseno, José A; Elliff, Jonah; Rojas Chavez, Roberth Anthony; Gao, Boning; Stokowy, Tomasz; Christakou, Eleni; Kursula, Petri; Micklem, David Robert; Gausdal, Gro; Haim, Hillel; Minna, John; Lorens, James Bradley; Maury, Wendy (Journal article; Peer reviewed, 2021)

  Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through virion-associated PS binding that is termed apoptotic mimicry. Here we show that this broadly shared uptake mechanism is utilized by ...

• Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry 

  Kulkarni, Amit; Ferreira, Tiago; Bretscher, Clemens; Grewenig, Annabel; El-Andaloussi, Nazim; Bonifati, Serena; Marttila, Tiina; Palissot, Valèrie; Hossain, Jubayer A.; Azuaje, Francisco; Miletic, Hrvoje; Ystaas, Lars Andreas Rømo; Golebiewska, Anna; Niclou, Simone Pierrette; Roeth, Ralf; Niesler, Beate; Weiss, Amélie; Brino, Laurent; Marchini, Antonio (Journal article; Peer reviewed, 2021)

  H-1 parvovirus (H-1PV) is a promising anticancer therapy. However, in-depth understanding of its life cycle, including the host cell factors needed for infectivity and oncolysis, is lacking. This understanding may guide ...

• Current status of thulium fibre laser lithotripsy: an up-to-date review 

  Jones, Patrick; Beisland, Christian; Ulvik, Øyvind (Journal article; Peer reviewed, 2021)

  Objective To perform an up-to-date review to scope the current status of the thulium fibre laser (TFL) in the setting of stone lithotripsy and provide a guide for the clinical urologist. Methods A review of world ...

• How Does Implant Survivorship Vary with Different Corail Femoral Stem Variants? Results of 51,212 Cases with Up to 30 Years Of Follow-up from the Norwegian Arthroplasty Register 

  Melbye, Silje Marie; Haug, Sofie Cecilia Dietrich; Fenstad, Anne Marie; Furnes, Ove Nord; Gjertsen, Jan-Erik; Hallan, Geir (Journal article; Peer reviewed, 2021)

  Background: The Corail® cementless stem (DePuy Synthes) has been used in Norway since 1987 and is one of the most frequently used stems in THA worldwide. Although the published survival results of the standard Corail stem ...

• The effect of Zhang’s guideline versus the WHO partograph on childbirth experience measured by the Childbirth Experience Questionnaire in the Labor Progression Study (LaPS): A cluster randomized trial 

  Rozsa, Daniella Judit; Dalbye, Rebecka; Bernitz, Stine; Blix, Ellen; Dalen, Ingvild; Braut, Geir Sverre; Eggebø, Torbjørn Moe; Øian, Pål; Sande, Ragnar Kvie (Journal article; Peer reviewed, 2021)

  Introduction Childbirth experience is an increasingly recognized and important measure of quality of obstetric care. Previous research has shown that it can be affected by intrapartum care and how labor is followed. A ...

• Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs 

  Shanbhag, Siddharth; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Yassin, Mohammed Ahmed Alamin Yousif; Dongre, Harsh Nitin; Costea, Daniela Elena; Tangl, Stefan; Stavropoulos, Andreas; Bolstad, Anne Isine; Suliman, Salwa; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021-11-30)

  Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation and bone regeneration capacity of mesenchymal stromal cells (MSC). Gingiva-derived progenitor cells (GPC) represent a less invasive alternative ...

• Variable expression of eighteen common housekeeping genes in human non-cancerous kidney biopsies 

  Strauss, Philipp; Furriol, Jessica; mikkelsen, Håvard (Journal article; Peer reviewed, 2021)

  Housekeeping, or reference genes (RGs) are, by definition, loci with stable expression profiles that are widely used as internal controls to normalize mRNA levels. However, due to specific events, such as pathological ...

• Gastrointestinal transit and contractility in diabetic constipation: A wireless motility capsule study on diabetes patients and healthy controls 

  Sangnes, Dag A.; Lundervold, Katarina; Bekkelund, Mattis; Volkmann, Hilde Løland Von; Berentsen, Birgitte; Gilja, Odd Helge; Dimcevski, Georg; Søfteland, Eirik (Journal article; Peer reviewed, 2021)

  Background: Diabetic constipation is traditionally attributed to slow colonic transit, despite limited evidence. More than half of patients find treatment unsatisfactory. To improve treatment, there is a need for better ...

• ILIVE Project Volunteer study. Developing international consensus for a European Core Curriculum for hospital end-of-life-care volunteer services, to train volunteers to support patients in the last weeks of life: A Delphi study 

  McGlinchey, Tamsin; Mason, Stephen R; Smeding, Ruthmarijke; Goosensen, Anne; Ruiz-Torreras, Inmaculada; Haugen, Dagny Renata Faksvåg; Bakan, Miša; Ellershaw, John E (Journal article; Peer reviewed, 2021)

  Background: Volunteers make a huge contribution to the health and wellbeing of the population and can improve satisfaction with care especially in the hospice setting. However, palliative and end-of-life-care volunteer ...

• A radiogenomics application for prognostic profiling of endometrial cancer 

  Høivik, Erling Andre; Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Fasmer, Kristine Eldevik; Berg, Hege Fredriksen; Halle, Mari Kyllesø; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)

  Prognostication is critical for accurate diagnosis and tailored treatment in endometrial cancer (EC). We employed radiogenomics to integrate preoperative magnetic resonance imaging (MRI, n = 487 patients) with histologic-, ...

• Management and outcomes in critically ill nonagenarian versus octogenarian patients 

  Bruno, Raphael Romano; Wernly, Bernhard; Kelm, Malte; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn H.; Artigas, Antonio; Finazzi, Stefano; Cecconi, Maurizio; Christensen, Steffen; Faraldi, Loredana; Lichtenauer, Michael; Flaatten, Hans; Jung, Christian (Journal article; Peer reviewed, 2021)

  Background: Intensive care unit (ICU) patients age 90 years or older represent a growing subgroup and place a huge financial burden on health care resources despite the benefit being unclear. This leads to ethical problems. ...

• EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1 

  Ando, Toshinori; Arang, Nadia; Wang, Zhiyong; Costea, Daniela Elena; Feng, Xiaodong; Goto, Yusuke; Izumi, Hiroki; Gilardi, Mara; Ando, Kazuyo; Gutkind, J. Silvio (Journal article; Peer reviewed, 2021)

  The Hippo pathway is frequently dysregulated in cancer, leading to the unrestrained activity of its downstream targets, YAP/TAZ, and aberrant tumor growth. However, the precise mechanisms leading to YAP/TAZ activation in ...

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