Faculty of Medicine
Recent Submissions
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Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review
(Journal article; Peer reviewed, 2024)Background Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify ... -
Clinical utility of novel diabetes subgroups in predicting vascular complications and mortality: up to 25 years of follow-up of the HUNT Study
(Journal article; Peer reviewed, 2024)Introduction Cluster analysis has previously revealed five reproducible subgroups of diabetes, differing in risks of diabetic complications. We aimed to examine the clusters’ predictive ability for vascular complications ... -
Proteomic Analysis of Human Serum Proteins Adsorbed onto Collagen Barrier Membranes
(Journal article; Peer reviewed, 2024)Collagen barrier membranes are frequently used in guided tissue and bone regeneration. The aim of this study was to analyze the signature of human serum proteins adsorbed onto collagen membranes using a novel protein ... -
Sex differences in clinically diagnosed psychiatric disorders over the lifespan: a nationwide register-based study in Sweden
(Journal article; Peer reviewed, 2024)Background Limited studies exist on sex differences in incidence rates of psychiatric disorders across the lifespan. This study aims to analyze sex differences in the incidence rates of clinically diagnosed psychiatric ... -
A severity comparison of leukoaraiosis in ischemic and hemorrhagic stroke: a retrospective study
(Journal article; Peer reviewed, 2024)Introduction: Leukoaraiosis (LA) is a common neuroradiological finding in patients suffering from stroke. Cerebral small-vessel disease (SVD) is one of the primary causes of both ischemic stroke and hemorrhagic stroke ... -
Clinical and imaging characteristics of patients with cardiac amyloidosis- a single center observational study
(Journal article; Peer reviewed, 2024)Amyloidosis is a disease characterized by the deposition of protein fibrils. Cardiac involvement is a significant factor in determining prognosis. This study aimed to examine the clinical profile, outcomes, and long-term ... -
Immune cell activity during anti-TNF treatment in patients with psoriasis and psoriatic arthritis
(Journal article; Peer reviewed, 2024)Psoriasis is a chronic, inflammatory skin disease characterized by a dysregulated immune response and systemic inflammation. Up to one-third of patients with psoriasis have psoriatic arthritis (PsA). Targeted treatment ... -
Treatment of Traumatic Dental Injuries in the Public Dental Services—A Qualitative Exploration of Perceived Challenges and Needs
(Journal article; Peer reviewed, 2025)Background/Aim This study explored perceived challenges in the management of traumatic dental injuries (TDI) among general dentists in the public dental service (PDS) of Vestland County in Western Norway and their needs ... -
Differences Between Traumatic and Degenerative Medial Meniscus Posterior Root Tears: A Systematic Review
(Journal article; Peer reviewed, 2025)Background: Intact meniscus roots are a prerequisite for normal meniscal function, including even distribution of compressive forces across the knee joint. An injury to the root disrupts the hoop strength of the meniscus ... -
Development of selective ssDNA micro-probe for PD1 detection as a novel strategy for cancer imaging
(Journal article; Peer reviewed, 2024)Programmed death receptor 1, PD1, modulates the function of immune cells by providing inhibitory signals and constitutes the marker of immune exhaustion. Monitoring the level of PD1 promises a useful diagnostic approach ... -
A temporary hospital intensive care unit: a preparedness concept to increase intensive care capacity
(Journal article; Peer reviewed, 2024)Introduction Norway faced the possibility of the most significant strain on its intensive care capacity in decades during the COVID-19 pandemic. All Regional Health Authorities in Norway were instructed to prepare for ... -
Can Machine Learning Correctly Predict Outcomes of Flexible Ureteroscopy with Laser Lithotripsy for Kidney Stone Disease? Results from a Large Endourology University Centre
(Journal article; Peer reviewed, 2024)Background and objective The integration of machine learning (ML) in health care has garnered significant attention because of its unprecedented opportunities to enhance patient care and outcomes. In this study, we trained ... -
MRI radiomics captures early treatment response in patient-derived organoid endometrial cancer mouse models
(Journal article; Peer reviewed, 2024)Background: Radiomics can capture microscale information in medical images beyond what is visible to the naked human eye. Using a clinically relevant mouse model for endometrial cancer, the objective of this study was to ... -
Polyethylene wear and cup migration of cemented total hip arthroplasty with femoral heads made of oxidized zirconium, steel, or cobalt chromium: a 10-year secondary analysis from a randomized trial using radiostereometry
(Journal article; Peer reviewed, 2024)Background and purpose: We aimed to evaluate polyethylene (PE) wear, cup migration, and clinical outcome over 10 years in total hip arthroplasties (THA) using different articulations. Methods: This is a secondary analysis ... -
A Nanobody-Based Proximity Ligation Assay Detects Constitutive and Stimulus-Regulated Native Arc/Arg3.1 Oligomers in Hippocampal Neuronal Dendrites
(Journal article; Peer reviewed, 2024)Activity-regulated cytoskeleton-associated protein (Arc), the product of an immediate early gene, plays critical roles in synaptic plasticity and memory. Evidence suggests that Arc function is determined by its oligomeric ... -
Review of Hydroxypropyl Methylcellulose in Artificial Tears for the Treatment of Dry Eye Disease
(Journal article; Peer reviewed, 2024)Dry eye disease (DED) is a highly prevalent condition, resulting in reduced quality of life, lower participation in social life and impaired work efficiency. Hydroxypropyl methylcellulose (HPMC) is a cellulose-based ... -
Development of 42 marker panel for in-depth study of cancer associated fibroblast niches in breast cancer using imaging mass cytometry
(Journal article; Peer reviewed, 2024)Imaging Mass Cytometry (IMC) is a novel, and formidable high multiplexing imaging method emerging as a promising tool for in-depth studying of tissue architecture and intercellular communications. Several studies have ... -
Transabdominal Ultrasound of the Stomach in Patients with Functional Dyspepsia: A Review
(Journal article; Peer reviewed, 2024)Background/Aim: Dyspepsia is a very common condition worldwide and has an immense impact on quality of life. Functional dyspepsia (FD) is defined by dyspeptic symptoms with the absence of any structural abnormality that ... -
Narrative review of occupational exposures and noncommunicable diseases
(Journal article; Peer reviewed, 2024)Objective Within the scope of the Exposome Project for Health and Occupational Research on applying the exposome concept to working life health, we aimed to provide a broad overview of the status of knowledge on occupational ... -
Factors leading to excessive fatigue in nurses – a three-year follow-up study
(Journal article; Peer reviewed, 2024)Global nursing shortages necessitate the identification of mitigatable factors that may reduce nursing absence and turnover. Fatigue has been shown to be associated with these issues. This study aimed to identify factors ...