• Novel biomarkers in patients with uncontrolled hypertension with and without kidney damage 

  Brobak, Karl Marius; Halvorsen, Lene Vernås; Aass, Hans Christian; Søraas, Camilla Lund; Aune, Arleen; Olsen, Erik; Bergland, Ola Undrum; Rognstad, Stine; Blom, Kjersti Benedicte; Birkeland, Jon Arne; Høieggen, Aud; Larstorp, Anne Cecilie Kjeldsen; Solbu, Marit Dahl (Journal article; Peer reviewed, 2024)

  Introduction Estimated glomerular filtration rate (eGFR) and urine albumin/creatinine ratio (ACR) are insensitive biomarkers for early detection of hypertension-mediated organ damage (HMOD). In this nationwide cross-sectional ...

• Reference intervals of circulating secretoneurin concentrations determined in a large cohort of community dwellers: the HUNT study 

  Aakre, Kristin Moberg; Lyngbakken, Magnus Nakrem; Faaren, Arne L.; Røsjø, Helge Rørvik; Dalen, Håvard; Omland, Torbjørn (Journal article; Peer reviewed, 2024)

  Objectives Secretoneurin (SN) is a novel cardiac biomarker that associates with the risk of mortality and dysfunctional cardiomyocyte Ca2+ handling in heart failure patients. Reference intervals for SN are unknown. M ...

• Clinicopathological and radiological stratification within FIGO 2018 stages improves risk-prediction in cervical cancer 

  Halle, Mari Kyllesø; Bozickovic, Olivera; Forsse, David Erik; Wagner-Larsen, Kari Strøno; Gold, Rose Meng; Lura, Njål; Woie, Kathrine; Bertelsen, Bjørn; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2024)

  Objective: Assess the added prognostic value of the updated International Federation of Gynecology and Obstetrics (FIGO) 2018 staging system, and to identify clinicopathological and radiological biomarkers for improved ...

• Age of onset for increased dose-adjusted serum concentrations of antidepressants and association with sex and genotype: An observational study of 34,777 individuals 

  Tveit, Kristine; Hermann, Monica; Nilsen, Roy Miodini; Wallerstedt, Susanna M.; Rongve, Arvid; Molden, Espen; Hole, Kristine (Journal article; Peer reviewed, 2024)

  Purpose The aim of this study was to examine the age of onset for increased dose-adjusted serum concentrations (C/D ratio) of common antidepressant drugs and to explore the potential association with sex and CYP2C19/CYP2D6 ...

• Evaluation of the nurse-assisted eHealth intervention ‘eHealth@Hospital-2-Home’ on self-care by patients with heart failure and colorectal cancer post-hospital discharge : protocol for a randomised controlled trial 

  Storm, Marianne; Morken, Ingvild Margreta; Austin, Rosalynn; Nordfonn, Oda Karin; Wathne, Hege Bjøkne; Urstad, Kristin Hjorthaug; Karlsen, Bjørg; Dalen, Ingvild; Gjeilo, Kari Hanne; Richardson, Alison; Elwyn, Glyn; Bru, Lars Edvin; Søreide, Jon Arne; Kørner, Hartwig; Moan, Rune; Strömberg, Anna; Lurås, Hilde; Husebø, Anne Marie Lunde (Journal article; Peer reviewed, 2024-01-04)

  Background: Patients with heart failure (HF) and colorectal cancer (CRC) are prone to comorbidity, a high rate of readmission, and complex healthcare needs. Self-care for people with HF and CRC after hospitalisation can ...

• The Therapeutic Mechanisms of Mesenchymal Stem Cells in MS—A Review Focusing on Neuroprotective Properties 

  Gavasso, Sonia; Kråkenes, Torbjørn; Olsen, Håkon; Evjenth, Elisabeth Claire; Ytterdal, Marie; Haugsøen, Jonas Bull; Kvistad, Christopher Elnan (Journal article; Peer reviewed, 2024-01-23)

  In multiple sclerosis (MS), there is a great need for treatment with the ability to suppress compartmentalized inflammation within the central nervous system (CNS) and to promote remyelination and regeneration. Mesenchymal ...

• Adverse events related to accessory devices used during ureteroscopy: Findings from a 10-year analysis of the Manufacturer and User Facility Device Experience (MAUDE) database 

  Juliebø-Jones, Patrick; Somani, Bhaskar K.; Mykoniatis, Ioannis; Hameed, B. M. Zeeshan; Tzelves, Lazaros; Æsøy, Mathias S.; Gjengstø, Peder; Moen, Christian Arvei; Beisland, Christian; Ulvik, Øyvind (Journal article; Peer reviewed, 2024)

  Objectives: The objective of this study was to evaluate adverse events and device events related to accessories used during ureteroscopy (URS). Materials and methods: Analysis was performed of the records available in ...

• Fatigue in Parkinson's Disease: A Proteomic Study of Cerebrospinal Fluid 

  Eidem, Live Egeland; Birkeland, Even; Austdal, Marie; Bårdsen, Kjetil; Lange, Johannes; Alves, Guido Werner; Berven, Frode Steingrimsen; Nilsen, Mari Mæland; Herlofson, Karen; Tysnes, Ole-Bjørn; Omdal, Roald (Journal article; Peer reviewed, 2024)

• Effects of Mesenchymal Stem Cell-Conditioned Medium on Osteonecrosis-Derived Rat Mesenchymal Stem Cells 

  Nisha, Sadia Nusrat (Master thesis, 2024-08-31)

• Fecal bacteria and short-chain fatty acids in irritable bowel syndrome: relations to subtype 

  Teige, Erica Sande; Hillestad, Eline; Steinsvik, Elisabeth Kjelsvik; Brønstad, Ingeborg; Lundervold, Arvid; Lundervold, Astri J.; Valeur, Jørgen; Hausken, Trygve; Jacobsen, Birgitte Berentsen; Lied, Gülen Arslan (Journal article; Peer reviewed, 2024)

  Background: The relationship between gut microbiota and irritable bowel syndrome (IBS) subtype is unclear. We aimed to explore whether differences in fecal bacteria composition and short-chain fatty acid (SCFA) levels were ...

• Lower Limits for Reporting High-Sensitivity Cardiac Troponin Assays and Impact of Analytical Performance on Patient Misclassification 

  Aakre, Kristin Moberg; Apple, Fred S.; Mills, Nicolas L.; Meex, Steven J.R.; Collinson, Paul O.; Hammarsten, Ola; Jaffe, Allan S.; Omland, Torbjørn; Sandoval, Yader; Cullen, Louise (Journal article; Peer reviewed, 2024)

  Background: Cardiac troponin measurements are indispensable for the diagnosis of myocardial infarction and provide useful information for long-term risk prediction of cardiovascular disease. Accelerated diagnostic pathways ...

• Repeat expansions in AR, ATXN1, ATXN2 and HTT in Norwegian patients diagnosed with amyotrophic lateral sclerosis 

  Novy, Camilla; Busk, Øyvind; Tysnes, Ole-Bjørn; Landa, Sigve Strand; Aanjesen, Tori Navestad; Alstadhaug, Karl Bjørnar; Bjerknes, Tale Litlere; Bjørnå, Ingrid Kristine; Bråthen, Geir; Dahl, Elin; Demic, Natasha; Fahlström, Maria; Flemmen, Heidi Øyen; Hallerstig, Erika Carina; HogenEsch, Ineke; Kampman, Margitta; Kleveland, Grethe; Kvernmo, Helene Ballo; Ljøstad, Unn; Maniaol, Angelina; Morsund, Aase Hagen; Nakken, Ola; Olsen, Cathrine Goberg; Schlüter, Katrin Ruth; Utvik, May-Sissel; Yaseen, Ryaz; Holla, Øystein Lunde; Holmøy, Trygve; Høyer, Helle (Journal article; Peer reviewed, 2024)

  Genetic repeat expansions cause neuronal degeneration in amyotrophic lateral sclerosis as well as other neurodegenerative disorders such as spinocerebellar ataxia, Huntington’s disease and Kennedy’s disease. Repeat expansions ...

• Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease 

  Gonzalez-Ortiz, Fernando; Kirsebom, Bjørn-Eivind Seljelid; Contador, José; Tanley, Jordan E.; Selnes, Per; Gisladottir, Berglind; Pålhaugen, Lene; Hemminghyth, Mathilde Suhr; Jarholm, Jonas Alexander; Skogseth, Ragnhild Eide; Bråthen, Geir; Grøndtvedt, Gøril; Bjørnerud, Atle; Tecelao, Sandra; Waterloo, Knut; Aarsland, Dag; Fernández-Lebrero, Aida; García-Escobar, Greta; Navalpotro-Gómez, Irene; Turton, Michael; Hesthamar, Agnes; Kac, Przemyslaw R.; Nilsson, Johanna; Luchsinger, Jose; Hayden, Kathleen M.; Harrison, Peter; Puig-Pijoan, Albert; Zetterberg, Henrik; Hughes, Timothy M.; Suárez-Calvet, Marc; Karikari, Thomas K.; Fladby, Tormod; Blennow, Kaj (Journal article; Peer reviewed, 2024)

  Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates ...

• Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies 

  Wang, Heling; Siow, Richard; Schmauck-Medina, Tomás Alejandro; Zhang, Jianying; Sandset, Per Morten; Filshie, Clare; Lund, Øystein; Partridge, Linda; Bergersen, Linda Hildegard; Juel Rasmussen, Lene; Palikaras, Konstantinos; Sotiropoulos, Ioannis; Storm-Mathisen, Jon; Rubinsztein, David C.; Spillantini, Maria Grazia; De Zeeuw, Chris I.; Watne, Leiv; Vyhnalek, Martin; Veverova, Katerina; Liang, Xiao; Tavernarakis, Nektarios; Bohr, Vilhelm A.; Yokote, Koutaro; Saarela, Janna Saija; Nilsen, Hilde; Gonos, Efstathios S.; Scheibye-Knudsen, Morten; Chen, Guobing; Kato, Hisaya; Selbæk, Geir; Fladby, Tormod; Nilsson, Per; Simonsen, Anne Gjøen; Aarsland, Dag; Hindkjær Lautrup, Sofie; Ottersen, Ole Petter; Cox, Lynne S.; Fang, Fei (Journal article; Peer reviewed, 2024)

  Unhealthy aging poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the aging process offers a promising approach to reduce the burden of a number of age-related diseases, such ...

• Preoperative fatty infiltration of paraspinal muscles assessed by MRI is associated with less improvement of leg pain 2 years after surgery for lumbar spinal stenosis 

  Banitalebi, Hasan; Hermansen, Erland; Hellum, Christian; Espeland, Ansgar; Storheim, Kjersti; Myklebust, Tor Åge; Indrekvam, Kari; Brisby, Helena; Weber, Clemens; Anvar, Masoud; Aaen, Jørn Ståle; Negård, Anne (Journal article; Peer reviewed, 2024)

  Abstract Purpose Fatty infiltration (FI) of the paraspinal muscles may associate with pain and surgical complications in patients with lumbar spinal stenosis (LSS). We evaluated the prognostic influence of MRI-assessed ...

• Implementing Clinical Guidelines for the Treatment of Psychosis: The Frontline Leaders’ Point of View. A Qualitative Study 

  Nordin, Håkan; Mathisen, Gro Ellen; Rørtveit, Kristine; Joa, Inge; Johannessen, Jan Olav; Ruud, Torleif; Hartveit, Miriam (Journal article; Peer reviewed, 2024)

  Background: Despite the large amount of leadership and implementation theories and recommendations, healthcare services continue to struggle with efficiently incorporating new knowledge. The questioning of conventional ...

• Couple Relationship Problems in General Practice : A multiple methods study of prevalence and experiences from discussions of couple relationship problems in GP consultations 

  Berge, Siri Dalsmo (Doctoral thesis, 2024-10-11)

  Bakgrunn: Samlivskvalitet er assosiert med fysisk og psykisk helse samt livslengde. Det mangler kunnskap om hvilken rolle samtaler om parforhold har og bør ha i allmennpraksis. Mål: Å kartlegge omfanget av samlivstemaer ...

• The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers' Disease 

  Hong, Yu; Zhang, Zhuoyuan; Yangzom, Tsering; Chen, Anbin; Lundberg, Bjørn Christian; Fang, Fei; Siller, Richard; Sullivan, Gareth John; Zeman, Jiri; Tzoulis, Charalampos; Bindoff, Laurence Albert; Liang, Xiao (Journal article; Peer reviewed, 2024)

  Alpers' syndrome is an early-onset neurodegenerative disorder usually caused by biallelic pathogenic variants in the gene encoding the catalytic subunit of polymerase-gamma (POLG), which is essential for mitochondrial DNA ...

• Population-based tuberculosis screening : Prevalence, incidence and cluster analysis in southern Ethiopia 

  Banti, Abiot Bezabeh (Doctoral thesis, 2024-10-25)

  Bakgrunn: Detyyt har vært mange internasjonale initiativer for å stoppe tuberkuloseepidemien, og både tuberkulosedødelighet og insidensrater faller globalt. Likevel er sykdommen en betydelig utfordring for befolkninger og ...

• Maternal mortality in Sidama Region, southern Ethiopia : Results from surveys on mortality and the coverage of available interventions 

  Kea, Aschenaki Zerihun (Doctoral thesis, 2024-10-22)

  Summary Background: Etiopia er et lavinntektsland hvor mødredødsfall er et stort samfunnshelse problem. I 2020 døde 10,000 mødre i Etiopia og dette representerte 3.6% av den globale byrden. Etiopia mangler et register ...

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