• Determinants and Consequences of Nutritional Status in Patients with Chronic Kidney Disease 

  Dahl, Helene (Doctoral thesis, 2022-10-20)

  Sammendrag Bakgrunn: Pasienter med kronisk nyresykdom møter mangfoldige utfordringer vedrørende deres ernæringsstatus, relatert til redusert nyrefunksjon, påfølgende metabolske forandringer, mangfoldige komorbiditeter ...

• Efficacy of fecal microbiota transplantation for patients with irritable bowel syndrome at 3 years after transplantation 

  El-Salhy, Magdy; Winkel, Renate; Casén, Christina; Hausken, Trygve; Gilja, Odd Helge; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2022)

  Background & Aims: The long-term efficacy and possible adverse events of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS) are unknown. This study performed a 3-year follow-up of the patients in our ...

• Burn mass casualty incidents in Europe: A European response plan within the European Union Civil Protection Mechanism 

  Almeland, Stian Kreken; Depoortere, Evelyn; Jennes, Serge; Sjöberg, Folke; Basanta, J. Alfonso Lozano; Zanatta, Sofia; Alexandru, Calin; Martinez-Mendez, José Ramón; van der Vlies, Cornelis H.; Hughes, Amy; Barret, Juan Å.; Moiemen, Naiem; Leclerc, Thomas (Journal article; Peer reviewed, 2022)

  Background: Burn care is centralized in highly specialized burn centers in Europe. These centers are of limited capacity and may be overwhelmed by a sudden surge in case of a burn mass casualty incident. Prior incidents ...

• Ultrafast Microscopy Imaging of Acoustic Cluster Therapy Bubbles: Activation and Oscillation 

  van Wamel, Annemieke; Mühlenpfordt, Melina; Hansen, Rune; Healey, Andrew; Villanueva, Flordeliza S.; Kotopoulis, Spiros; Davies, Catharina de Lange; Chen, Xucai (Journal article; Peer reviewed, 2022)

  Acoustic Cluster Therapy (ACT®) is a platform for improving drug delivery and has had promising pre-clinical results. A clinical trial is ongoing. ACT® is based on microclusters of microbubbles–microdroplets that, when ...

• Quality of dietary fat and risk of Alzheimer’s disease and dementia in adults aged ≥50 years: a systematic review 

  Nwaru, Bright I.; Dierkes, Jutta; Ramel, Alfons; Arnesen, Erik Kristoffer; Thorisdottir, Birna; Lamberg-Allardt, Christel; Söderlund, Fredrik; Bärebring, Linnea; Åkesson, Agneta (Journal article; Peer reviewed, 2022)

  Objective: To identify, critically appraise, and synthesize evidence on the effect of quality of dietary fat intake and different classes of fatty acids on the risk of Alzheimer’s disease (AD) and dementia in adults aged ...

• Abuse and revictimization in adulthood in multiple sclerosis: a cross-sectional study during pregnancy 

  Eid, Karine; Torkildsen, Øivind; Aarseth, Jan Harald; Celius, Elisabeth Gulowsen; Cortese, Marianna; Holmøy, Trygve; Kapali, Akash; Myhr, Kjell-Morten; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)

  Background: Knowledge concerning exposure to abuse in adulthood and in pregnancy in people with multiple sclerosis (MS) is sparse. Objective: To determine the occurrence of adult abuse and abuse in relation to pregnancy ...

• Insall proximal realignment with/without tibial tubercle osteotomy for recurrent patellar instability yields acceptable medium- to long-term results but risk of osteoarthritis progression is considerable 

  Waaler, Per Arne Skarstein; Jellestad, Truls; Hysing-Dahl, Trine; Elvehøy, Elise; Inderhaug, Eivind (Journal article; Peer reviewed, 2022-07-06)

  Purpose: The purpose of this study was to evaluate clinical and radiological results in patients operated for recurrent patellar instability with a surgical approach consisting of Insall proximal realignment with/without ...

• Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia 

  Bruserud, Øystein; Reikvam, Håkon; Brenner, Annette (Journal article; Peer reviewed, 2022-01-23)

  Toll-like receptor 4 (TLR4) is a pattern-recognizing receptor that can bind exogenous and endogenous ligands. It is expressed by acute myeloid leukemia (AML) cells, several bone marrow stromal cells, and nonleukemic cells ...

• Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study 

  Pettersen, Trond Røed; Schjøtt, Jan Didrik; Allore, Heather G; Bendz, Bjørn; Borregaard, Britt; Fridlund, Bengt Gotthard Anton; Larsen, Alf Inge; Nordrehaug, Jan Erik; Rotevatn, Svein; Wentzel-Larsen, Tore; Norekvål, Tone Merete (Journal article; Peer reviewed, 2022)

  Objective: To determine patient perceptions of generic medicines 2 and 6 months after percutaneous coronary intervention (PCI), and to determine whether these perceptions moderate medication adherence. Design: Prospective ...

• Cortical thickness changes after computerized working memory training in patients with mild cognitive impairment 

  Hol, Haakon Ramsland; Flak, Marianne Møretrø; Chang, Linda; Løhaugen, Gro; Bjuland, Knut Jørgen; Rimol, Lars Morten; Engvig, Andreas; Skranes, Jon Sverre; Ernst, Thomas; Madsen, Bengt-Ove; Hernes, Susanne M S (Journal article; Peer reviewed, 2022-04-04)

  Background: Adaptive computerized working memory (WM) training has shown favorable effects on cerebral cortical thickness as compared to non-adaptive training in healthy individuals. However, knowledge of WM training-related ...

• CA-125 levels are predictive of survival in low-grade serous ovarian cancer—A multicenter analysis 

  Wohlmuth, Christoph; Djedovic, Vladimir; Kjær, Susanne K.; Jensen, Allan; Glasspool, Rosalind; Roxburgh, Patricia; Defazio, Anna; Johnatty, Sharon E.; Webb, Penelope M.; Modugno, Francesmary; Lambrechts, Diether; Schildkraut, Joellen M.; Berchuck, Andrew; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Høgdall, Estrid; Høgdall, Claus K.; Goode, Ellen L.; Winham, Stacey J.; Matsuo, Keitaro; Karlan, Beth Y.; Lester, Jenny; Goodman, Marc T.; Thompson, Pamela J.; Pejovic, Tanja; Riggan, Marjorie J.; Lajkosz, Katherine; Tone, Alicia; May, Taymaa (Journal article; Peer reviewed, 2022-04-13)

  Objective: Studies on low-grade serous ovarian cancer (LGSC) are limited by a low number of cases. The aim of this study was to define the prognostic significance of age, stage, and CA-125 levels on survival in a ...

• The Association between Serum Serine and Glycine and Related-Metabolites with Pancreatic Cancer in a Prospective Cohort Study 

  Luu, Hung N.; Paragomi, Pedram; Wang, Renwei; Huang, Joyce Y.; Adams-Haduch, Jennifer; Midttun, Øivind; Ulvik, Arve; Nguyen, Tin C.; Brand, Randall E.; Gao, Yutang; Ueland, Per Magne; Yuan, Jian-Min (Journal article; Peer reviewed, 2022-04-28)

  Background: Serine and glycine play an important role in the folate-dependent one-carbon metabolism. The metabolism of serine and glycine has been shown to be associated with cancer cell proliferation. No prior epidemiologic ...

• A Novel Prophylaxis Strategy Using Liposomal Vaccine Adjuvant CAF09b Protects against Influenza Virus Disease 

  Zimmermann, Julie; Schmidt, Signe Tandrup; Trebbien, Ramona; Cox, Rebecca Jane; Zhou, Fan; Follmann, Frank; Pedersen, Gabriel Kristian; Christensen, Dennis (Journal article; Peer reviewed, 2022-02-06)

  The SARS-CoV-2 pandemic caused a massive health and societal crisis, although the fast development of effective vaccines reduced some of the impact. To prepare for future respiratory virus pandemics, a pan-viral prophylaxis ...

• Put your weight behind it—Effect of body mass index on the active second stage of labour: A retrospective cohort study 

  Østborg, Tilde Broch; Sande, Ragnar; Kessler, Jørg; Tappert, Christian; Von, Brandis Philip; Eggebø, Torbjørn Moe (Journal article; Peer reviewed, 2022)

  Objective: To explore the duration of the active phase of the second stage of labour in relation to maternal pre-pregnant body mass index (BMI). Design: Retrospective cohort study. Setting: Labour wards of three ...

• Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain 

  Holmgren, Asbjørn; Hansson, Lars; Bjerkaas-Kjeldal, Kristine; Impellizzeri, Agata Antonia Rita; Gilfillan, Gregor; Djurovic, Srdjan; Hughes, Timothy (Journal article; Peer reviewed, 2022)

  The gene ankyrin-3 (ANK3) has been consistently associated with bipolar disorder (BD) in several genome-wide association studies (GWAS). The exact molecular mechanisms underlying this genetic association remain unknown. ...

• Prenatal dexamethasone treatment for classic 21-hydroxylase deficiency in Europe 

  Nowotny, Hanna; Neumann, Uta; Tardy-Guidollet, Veronique; Faisal Ahmed, Ahmed; Baronio, Federico; Battelino, Tadej; Bertherat, Jerome; Blankenstein, Oliver; Bonomi, Marco; Bouvattier, Claire; De la Perrière, Aude Brac; Brucker, Sara; Cappa, Marco; Chanson, Philippe; Van der Grinten, Hedi L. Claahsen; Colao, Annamaria; Cools, Martine; Davies, Justin H.; Dorr, Helmut-Gunther; Fenske, Wiebke K.; Ghigo, Ezio; Giordano, Roberta; Gravholt, Claus H.; Huebner, Angela; Husebye, Eystein Sverre; Igbokwe, Rebecca; Juul, Anders; Kiefer, Florian W.; Leger, Juliane; Menassa, Rita; Meyer, Gesine; Neocleous, Vassos; Phylactou, Leonidas A.; Rohayem, Julia; Russo, Gianni; Scaroni, Carla; Touraine, Philippe; Unger, Nicole; Vojtkova, Jarmila; Yeste, Diego; Lajic, Svetlana; Reisch, Nicole (Journal article; Peer reviewed, 2022)

  Objective: To assess the current medical practice in Europe regarding prenatal dexamethasone (Pdex) treatment of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. Design and methods: A questionnaire ...

• Factors associated with coronary heart disease in COPD patients and controls 

  Svendsen, Christina D.; Kuiper, Karel Kier-Jan; Ostridge, Kristoffer; Larsen, Terje Hjalmar; Nielsen, Rune; Hodneland, Vidar; Nordeide, Eli; Bakke, Per S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2022-04-27)

  Background: COPD and coronary heart disease (CHD) frequently co-occur, yet which COPD phenotypes are most prone to CHD is poorly understood. The aim of this study was to see whether COPD patients did have a true higher ...

• Safety and Clinical Efficacy of Mesenchymal Stem Cell Treatment in Traumatic Spinal Cord Injury, Multiple Sclerosis and Ischemic Stroke – A Systematic Review and Meta-Analysis 

  Kvistad, Christopher Elnan; Kråkenes, Torbjørn; Gjengedal, Gudveig Cecilie Gjerde; Mustafa, Kamal Babikeir Elnour; Rekand, Tiina; Bø, Lars (Journal article; Peer reviewed, 2022-05-30)

  Background: Mesenchymal stem cells (MSCs) is an attractive candidate in regenerative research and clinical trials have assessed their therapeutic potential in different neurological conditions with disparate etiologies. ...

• Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain 

  Bråten, Lars Christian Haugli; Grøvle, Lars; Wigemyr, Monica; Wilhelmsen, Maja; Gjefsen, Elisabeth; Espeland, Ansgar; Haugen, Anne Julsrud; Skouen, Jan Sture; Brox, Jens Ivar; Zwart, John Anker Henrik; Storheim, Kjersti; Ostelo, Raymond WJG.; Grotle, Margreth (Journal article; Peer reviewed, 2022)

  Objectives: The objective of this study was to estimate the minimal important change (MIC) and responsiveness of core patient reported outcome measures for chronic low back pain (LBP) and Modic changes. Study Design and ...

• Acute kidney injury in patients with COVID-19 in the intensive care unit: Evaluation of risk factors and mortality in a national cohort 

  Aukland, Eirik Aasen; Klepstad, Pål; Aukland, Stein Magnus; Zamanzad Ghavidel, Fatemeh; Buanes, Eirik Alnes (Journal article; Peer reviewed, 2022)

  Objectives: Acute kidney injury (AKI) is a frequent complication among critical ill patients with COVID-19, but the actual incidence is unknown as AKI-incidence varies from 25% to 89% in intensive care unit (ICU) populations. ...

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