• The efectiveness of exercise therapy and education plus cognitive behavioral therapy, alone or in combination with total knee arthroplasty in patients with knee osteoarthritis – study protocol for the MultiKnee trial 

  Lindberg, Maren Falch; Aamodt, Arild; Badawy, Mona; Bergvad, Ingvild Buset; Borchgrevink, Petter Chr.; Furnes, Ove Nord; Gay, Caryl; Heir, Stig; Holm, Inger; Indrekvam, Kari; Kise, Nina Jullum; Lau, Bjørn; Magnussen, Jon; Nerhus, Tor Kjetil; Rognsvåg, Turid; Rudsengen, Daniil; Rustøen, Tone; Skou, Søren Thorgaard; Stubberud, Jan Egil; Småstuen, Milada Cvancarova; Lerdal, Anners (Journal article; Peer reviewed, 2021)

  Background One in five patients report chronic pain following total knee arthroplasty (TKA) and are considered non-improvers. Psychological interventions such as cognitive behavioral therapy (CBT), combined with exercise ...

• Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of infammation measured three months after ischemic stroke 

  Alme, Katinka Nordheim; Ulvik, Arve; Askim, Torunn; Assmus, Jörg; Mollnes, Tom Eirik; Naik, Mala; Næss, Halvor; Saltvedt, Ingvild; Ueland, Per-Magne; Knapskog, Anne Brita (Journal article; Peer reviewed, 2021)

  Background Chronic low-grade inflammation is associated with both ischemic stroke and sedentary behaviour. The aim of this study was to investigate the predictive abilities of biomarkers of inflammation and immune modulation ...

• Variations in the management of diffuse low-grade gliomas - A Scandinavian multicenter study 

  Munkvold, Bodil Karoline Ravn; Solheim, Ole; Bartek, Jiri; Corell, Alba; De Dios, Eddie; Gulati, Sasha; Helseth, Eirik; Holmgren, Klas; Jensdottir, Margret; Lundborg, Mina; Mireles, Eduardo Erasmo Mendoza; Mahesparan, Rupavathana; Tveiten, Øystein Vesterli; Milos, Peter; Redebrandt, Henrietta Nittby; Pedersen, Lars Kjelsberg; Ramm-Pettersen, Jon-Terje; Sjöberg, Rickard L; Sjögren, Björn; Sjåvik, Kristin; Smits, Anja; Tomasevic, Gregor; Vecchio, Tomás Gómez; Vik-Mo, Einar O.; Zetterling, Maria; Salvesen, Øyvind; Jakola, Asgeir Store (Journal article; Peer reviewed, 2021)

  Background Early extensive surgery is a cornerstone in treatment of diffuse low-grade gliomas (DLGGs), and an additional survival benefit has been demonstrated from early radiochemotherapy in selected “high-risk” patients. ...

• Best Practice Recommendations for the Implementation of a Digital Pathology Workflow in the Anatomic Pathology Laboratory by the European Society of Digital and Integrative Pathology (ESDIP) 

  Fraggetta, Filippo; L'Imperio, Vincenzo; Ameisen, David; Carvalho, Rita; Leh, Sabine; Kiehl, Tim-Rasmus; Serbanescu, Mircea; Racoceanu, Daniel; Mea, Vincenzo Della; Polonia, Antonio; Zerbe, Norman; Eloy, Catarina (Journal article; Peer reviewed, 2021)

  The interest in implementing digital pathology (DP) workflows to obtain whole slide image (WSI) files for diagnostic purposes has increased in the last few years. The increasing performance of technical components and the ...

• Current Status of Intravesical Therapies for Bladder Pain Syndrome (BPS): A Narrative Review of Emerging Evidence 

  Jones, Patrick; Hjelle, Karin Margrethe; Mohn, Jannike; Gudbrandsdottir, Gigja; Roth, I; Chaudhry, Adeel Asghar; Bergesen, Anne Kvåle; Beisland, Christian (Journal article; Peer reviewed, 2021)

  Bladder pain syndrome (BPS) is a complex condition, which can have debilitating sequelae for patients. Many elements of BPS remain poorly understood including pathophysiology, diagnosis and treatment. Navigating patient ...

• AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model 

  Chen, Tony Jialiang; Mydel, Piotr Mateusz; Benedyk-Machaczka, Małgorzata; Kamińska, Marta; Kalucka, Urszula; Blø, Magnus; Furriol, Jessica; Gausdal, Gro; Lorens, James Bradley; Osman, Tarig Al-Hadi; Marti, Hans Peter (Journal article; Peer reviewed, 2021)

  AXL tyrosine kinase activation enhances cancer cell survival, migration, invasiveness, and promotes drug resistance. AXL overexpression is typically detected in a high percentage of renal cell carcinomas (RCCs) and is ...

• Retinal haemorrhage in infants investigated for suspected maltreatment is strongly correlated with intracranial pathology 

  Thiblin, Ingemar; Andersson, Jacob; Wester, Knut; Högberg, Göran; Högberg, Ulf (Journal article; Peer reviewed, 2021)

  Aim To test the two prevailing hypotheses regarding the aetiology of infant retinal haemorrhage: (a) traction forces exerted by the lens and/or corpus vitreum on the retina during infant shaking or (b) retinal vessel ...

• Rules and regulations for a pregnant endourologist: the European perspective 

  Jones, Charles Patrick Warburton; Pietropaolo, Amelia; Spinoit, Anne-Francoise; Bergesen, Anne Kvåle; Gudbrandsdottir, Gigja; Beisland, Christian; von Ostau, Nicola; Harke, Nina N.; Ribal, Maria J.; Zerva, Maria; Bres-Niewada, Ewa; Zondervan, Patricia; McLornan, Liza; Ferretti, Stefania; Tonnhofer, Ursula; Necknig, Ulrike Hendrika; Skolarikos, Andreas; Somani, Bhaskar K. (Journal article; Peer reviewed, 2021)

  Introduction Working in surgery while pregnant is challenging. Navigating this period safely is of paramount importance. Anecdotal observation suggests that there exists great variation among European nations in regard ...

• Characterization of immune cell infiltrate in tumor stroma and epithelial compartments in oral squamous cell carcinomas of Sudanese patients 

  Mohamed, Nuha Mohamed Gaafar; Osman, Tarig Al-Hadi; Ahmed, Israa A.H.; Elsheikh, Mariam; Dongre, Harsh Nitin; Jacobsen, Martha Rolland; Mohamed, Nazar; Fromreide, Siren; Suleiman, Ahmed Mohamed; Johannessen, Anne Christine; Nginamau, Elisabeth Sivy; Costea, Daniela Elena (Journal article; Peer reviewed, 2021)

  Background Tumor immune infiltrate has been explored in oral squamous cell carcinoma (OSCC), but studies on simultaneous characterization of multiple immune cell subtypes separately in stromal and intraepithelial tumor ...

• Assessment of markers of gut integrity and inflammation in non-celiac gluten sensitivity after a gluten free-diet 

  Dale, Hanna Fjeldheim; Johannessen, Julianne Cecilie Høibak; Brønstad, Ingeborg; Lied, Gülen Arslan (Journal article; Peer reviewed, 2021)

  Purpose: Markers for gut integrity and inflammation have received increasing interest as intestinal permeability and innate immune system activation are suggested as possible pathophysiological mechanisms in non-celiac ...

• Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study 

  Lin, Yan; Maihofer, Adam X.; Stapp, Emma; Ritchey, Megan; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H; Bertram, Holli; Bhattacharjee, Abesh; Calkin, Cynthia V.; Conroy, Carla; Coryell, William; D´Arcangelo, Nicole; DeModena, Anna; Biernacka, Joanna M.; Fisher, Carrie; Frazier, Nicole; Frye, Mark; Gao, Keming; Garnham, Julie; Gershon, Elliot; Glazer, Kara; Goes, Fernando S; Goto, Toyomi; Karberg, Elizabeth; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; Stautland, Andrea; McCarthy, Michael J.; McInnis, Melvin G.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Ødegaard, Ketil Joachim; Syrstad, Vigdis Elin Giæver; Ryan, Kelly; Schinagle, Martha; Schøyen, Helle Kristine; Andreassen, Ole; Shaw, Martha; Shilling, Paul D.; Slaney, Claire; Tarwater, Bruce; Calabrese, Joseph R.; Alda, Martin; Nievergelt, Caroline M.; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2021)

  Background Lithium is regarded as a first-line treatment for bipolar disorder (BD), but partial response and non-response commonly occurs. There exists a need to identify lithium non-responders prior to initiating treatment. ...

• No difference in risk of hospitalization between reported cases of the SARS-CoV-2 Delta variant and Alpha variant in Norway 

  Veneti, Lamprini; Valcarcel Salamanca, Beatriz; Seppälä, Elina Marjukka; Starrfelt, Jostein; Storm, Margrethe Larsdatter; Bragstad, Karoline; Hungnes, Olav; Bøås, Håkon; Kvåle, Reidar; Vold, Line; Nygård, Karin Maria; Buanes, Eirik Alnes; Whittaker, Robert Neil (Journal article; Peer reviewed, 2022)

  Objectives To estimate the risk of hospitalization among reported cases of the Delta variant of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) compared with the Alpha variant in Norway, and the risk of ...

• Cardiovascular changes in young renal failure patients 

  Tøndel, Camilla; Marti, Hans Peter (Journal article; Peer reviewed, 2021)

  Progresses in medical care of severe kidney disease and congenital anomalies of kidney and urinary tract make it possible for a higher percentage of young renal failure patients to survive and enter adulthood. There is ...

• Effects of Intraoperative Dexmedetomidine Infusion on Postoperative Pain after Craniotomy: A Narrative Review 

  Syrous, Nesjla Sofia; Sundstrøm, Terje; Softeland, Eirik; Jammer, Ib (Journal article; Peer reviewed, 2021)

  Publisert Hovedoppgave UiB for Stud Med Nesjla Sofia Syrous: Effekter av intraoperativ dexmedetomidine infusjon på postoperative smerter etter craniotomi, en litteraturoversikt.

• Placental histology predicted adverse outcomes in extremely premature neonates in Norway-population-based study 

  Budal, Elisabeth Berge; Ebbing, Cathrine; Kessler, Jørg; Bains, Sukhjeet; Haugen, Olav H.; Aukland, Stein Magnus; Eide, Geir Egil; Halvorsen, Thomas; Bentsen, Mariann; Collett, Karin (Journal article; Peer reviewed, 2021)

  Aim We evaluated the role of placental pathology in predicting adverse outcomes for neonates born extremely preterm (EPT) before 28 weeks of gestation. Methods This was a prospective observational study of 123 extremely ...

• The Effect of Posterior Tibial Slope on the Risk of Revision Surgery After Anterior Cruciate Ligament Reconstruction 

  Dæhlin, Lene; Inderhaug, Eivind; Strand, Torbjørn; Parkar, Anagha P; Solheim, Eirik (Journal article; Peer reviewed, 2022)

  Background: A significant proportion of patients undergoing anterior cruciate ligament (ACL) reconstruction (ACLR) later experience graft failure. Some studies suggest an association between a steep posterior tibial slope ...

• Hospital care for the dying patient with cancer: does an advance care planning invitation influence bereaved relatives' experiences? A two country survey 

  Hjorth, Nina Elisabeth; Hufthammer, Karl Ove; Sigurdardottir, Katrin Rut; Tripodoro, Vilma Adriana; Goldraij, Gabriel; Kvikstad, Anne; Haugen, Dagny Renata Faksvåg (Journal article; Peer reviewed, 2021)

  Objectives Advance care planning (ACP) is not systematically performed in Argentina or Norway. We used the post-bereavement survey of the ERANet-LAC International Care Of the Dying Evaluation (CODE) project (2017–2020) to ...

• Prevalence of atherosclerosis and association with 5-year outcome: The Norwegian Stroke in the Young Study 

  Nawaz, Beenish; Fromm, Annette; Øygarden, Halvor; Eide, Geir E; Saeed, Sahrai; Meijer, Rudy; Bots, Michiel L; Sand, Kristin M; Thomassen, Lars; Næss, Halvor; Waje-Andreassen, Ulrike (Journal article; Peer reviewed, 2021)

  Objectives: We studied the prevalence of atherosclerosis among ischaemic stroke patients ≤60 years and controls at the time of the index stroke, and its association with occurrence of new cardiovascular events (CVEs) and ...

• Development of and Gathering Validity Evidence for a Theoretical Test in Contrast-Enhanced Ultrasound 

  Jacobsen, Niels; Nolsøe, Christian P.; Konge, Lars; Graumann, Ole; Dietrich, Christoph F.; Sidhu, Paul S.; Gilja, Odd H.; Meloni, Maria F.; Berzigotti, Annalisa; Harvey, Chris J.; Deganello, Annamaria; Prada, Francesco; Lerchbaumer, Markus H.; Laursen, Christian B. (Journal article; Peer reviewed, 2022)

  Contrast-enhanced ultrasound (CEUS) is an imaging modality applied in a broad field of medical specialties for diagnostic uses, guidance during biopsy procedures and ablation therapies and sonoporation therapy. Appropriate ...

• Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations 

  König, Marton; Lorentzen, Åslaug Rudjord; Torgauten, Hilde Marie; Tran, The Trung; Schikora-Rustad, Stine; Vaage, Eline Benno; Mygland, Åse Daasvand; Wergeland, Stig; Aarseth, Jan Harald; Aaberge, Ingeborg Sundsvalen; Torkildsen, Øivind; Holmøy, Trygve; Berge, Tone; Myhr, Kjell-Morten; Harbo, Hanne-Cathrin Flinstad; Andersen, Jan Terje; Munthe, Ludvig Andre; Søraas, Arne Vasli; Celius, Elisabeth Gulowsen; Vaage, John T.; Lund-Johansen, Fridtjof; Nygaard, Gro Owren (Journal article; Peer reviewed, 2021)

  Introduction The effect of disease-modifying therapies (DMT) on vaccine responses is largely unknown. Understanding the development of protective immunity is of paramount importance to fight the COVID-19 pandemic. Objective ...

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