• Nuclear and Mitochondrial Circulating Cell-Free DNA Is Increased in Patients With Inflammatory Bowel Disease in Clinical Remission 

  Vrablicova, Zuzana; Tomova, Kristina; Tothova, Lubomira; Babickova, Janka; Gromova, Barbora; Konecna, Barbora; Liptak, Robert; Hlavaty, Tibor; Gardlik, Roman (Journal article; Peer reviewed, 2020)

  Background: The role of cell-free DNA (cfDNA) in the pathogenesis of inflammatory bowel disease (IBD) has been recently suggested. The aim of this study was to analyze circulating cfDNA and deoxyribonuclease (DNase) activity ...

• Automated segmentation of endometrial cancer on MR images using deep learning 

  Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Solteszova, Veronika; Zanna, Antonella; Fasmer, Kristine Eldevik; Krakstad, Camilla; Lundervold, Arvid; Lundervold, Alexander Selvikvåg; Salvesen, Øyvind; Erickson, Bradley J.; Haldorsen, Ingfrid S (Journal article; Peer reviewed, 2021)

  Preoperative MR imaging in endometrial cancer patients provides valuable information on local tumor extent, which routinely guides choice of surgical procedure and adjuvant therapy. Furthermore, whole-volume tumor analyses ...

• A hospital based epidemiological study of genetically determined muscle disease in south western Norway 

  Husebye, Sylvia Adele; Rebne, Camilla Bratt; Stokland, Ann-Elin Meling; Sanaker, Petter Schandl; Bindoff, Laurence (Journal article; Peer reviewed, 2020)

  We determined the prevalence of genetically determined neuromuscular diseases in adult Norwegian patients from Hordaland County. We identified patients using International Classification of Disease codes registered in our ...

• Trajectories of psychiatric disorders in a cohort of children with cerebral palsy across four years 

  Bjørgaas, Hanne Marit; Elgen, Irene Bircow; Hysing, Mari (Journal article; Peer reviewed, 2021)

  Background: Risk of psychiatric disorders has been reported for children and adolescents with cerebral palsy (CP) at different ages, however little is known regarding the long-term trajectories of these disorders. Objective: ...

• Cryoneurolysis for cervicogenic headache - A double blinded randomized controlled study 

  Kvarstein, Gunnvald; Högström, Henrik; Allen, Sara Maria; Rosland, Jan Henrik (Journal article; Peer reviewed, 2020)

  Background and aims: Cervicogenic headache (CEH) is a debilitating condition and analgesics have limited effect. Percutaneous cryoneurolysis is thus still in use although the clinical evidence is lacking. We present a ...

• Development of an international Core Outcome Set (COS) for best care for the dying person: study protocol 

  Zambrano, Sofia C; Haugen, Dagny Faksvåg; van der Heide, Agnes; Tripodoro, Vilma Adriana; Ellershaw, John; Fürst, Carl Johan; Voltz, Raymond; Mason, Stephen; Daud, Maria L; De Simone, Gustavo; Halfdanardottir, Svandis; Sigurdardottir, Valgerdur; Johnson, Jeremy; Allan, Simon; Hafeez, Haroon; Simoes, Catarina; Sigurdardottir, Katrin Rut; Rasmussen, Birgit H.; Williamson, Paula; Eychmüller, Steffen (Journal article; Peer reviewed, 2020-11-30)

  Background: In contrast to typical measures employed to assess outcomes in healthcare such as mortality or recovery rates, it is difficult to define which specific outcomes of care are the most important in caring for dying ...

• The Effects of Fecal Microbiota Transplantation on the Symptoms and the Duodenal Neurogenin 3, Musashi 1, and Enteroendocrine Cells in Patients With Diarrhea-Predominant Irritable Bowel Syndrome 

  Mazzawi, Tarek; El-Salhy, Magdy; Lied, Gülen Arslan; Hausken, Trygve (Journal article; Peer reviewed, 2021)

  Introduction: Interactions between the gut microbiota and enteroendocrine cells play important role in irritable bowel syndrome (IBS). Reduced stem cell densities and their differentiation into enteroendocrine cells may ...

• HSP27 Expression as a Novel Predictive Biomarker for Bevacizumab: is it Cost Effective? 

  Seo, Mikyung Kelly; Straume, Oddbjørn; Akslen, Lars A.; Cairns, John Alexander (Journal article; Peer reviewed, 2020)

  Background: Despite the extensive use of bevacizumab in a range of oncology indications, the US FDA revoked its approval for breast cancers, and multiple negative trials in several solid malignancies have been reported, ...

• Plasma Concentrations of Extracellular DNA in Acute Kidney Injury 

  Homolová, Jordanka; Janovičová, L'ubica; Konečná, Barbora; Vlková, Barbora; Celec, Peter; Tóthová, L'ubomíra; Babickova, Janka (Journal article; Peer reviewed, 2020)

  Current diagnostic methods of acute kidney injury (AKI) have limited sensitivity and specificity. Tissue injury has been linked to an increase in the concentrations of extracellular DNA (ecDNA) in plasma. A rapid turnover ...

• Comparing screening outcomes for digital breast tomosynthesis and digital mammography by automated breast density in a randomized controlled trial: Results from the to-be trial 

  Moshina, Nataliia; Aase, Hildegunn Siv; Danielsen, Anders Skyrud; Haldorsen, Ingfrid S.; Lee, Christoph I.; Zackrisson, Sophia; Hofvind, Solveig (Journal article; Peer reviewed, 2020)

  Background: Digital breast tomosynthesis (DBT) is considered superior to digital mammography (DM) for women with dense breasts. Purpose: To identify differences in screening outcomes, including rates of recall, ...

• Causal modelling of variation in clinical practice and long-term outcomes of ADHD using Norwegian registry data: The ADHD controversy project 

  Mykletun, Arnstein; Widding-Havneraas, Tarjei; Chaulagain, Ashmita; Lyhmann, Ingvild; Bjelland, Ingvar; Halmøy, Anne; Elwert, Felix; Butterworth, Peter; Markussen, Simen; Zachrisson, Henrik Daae; Rypdal, Knut (Journal article; Peer reviewed, 2021)

  Introduction Attention-deficit/hyperactivity disorder (ADHD) is among the most common mental disorders in children and adolescents, and it is a strong risk factor for several adverse psychosocial outcomes over the lifespan. ...

• Antibiotic-loaded bone cement in prevention of periprosthetic joint infections in primary total knee arthroplasty: A register-based multicentre randomised controlled non-inferiority trial (ALBA trial) 

  Leta, Tesfaye Hordofa; Gjertsen, Jan-Erik; Dale, Håvard; Hallan, Geir; Lygre, Stein Håkon Låstad; Fenstad, Anne Marie; Dyrhovden, Gro Sævik; Westberg, Marianne; Wik, Tina Strømdal; Jakobsen, Rune Bruhn; Aamodt, Arild; Röhrl, Stephan Maximillian; Gøthesen, Øystein Johannes; Lindalen, Einar; Heir, Stig; Ludvigsen, Jarle; Bruun, Trond; Hansen, Ann Kristin; Aune, Knut Erik Moen; Warholm, Marianne; Skjetne, John Petter; Badawy, Mona; Høvding, Pål; Husby, Otto Schnell; Karlsen, Øystein Espeland; Furnes, Ove Nord (Journal article; Peer reviewed, 2021)

  Introduction The current evidence on the efficacy of antibiotic-loaded bone cement (ALBC) in reducing the risk of periprosthetic joint infections (PJI) after primary joint reconstruction is insufficient. In several European ...

• Comorbidity in multiple sclerosis patients from Nordland County, Norway - validated data from the Norwegian Patient Registry 

  Benjaminsen, Espen; Myhr, Kjell-Morten; Torkildsen, Nina Agnethe Grytten; Alstadhaug, Karl Bjørnar (Journal article; Peer reviewed, 2021)

  Background: Knowledge of comorbid disorders is important to optimize therapy for multiple sclerosis (MS), but data are limited. The aim of this study was to assess comorbidity in persons with MS living in Nordland County ...

• Brain atrophy and employment in multiple sclerosis patients: a 10-year follow-up study 

  Jacobsen, Cecilie; Zivadinov, Robert; Myhr, Kjell-Morten; Dalaker, Turi Olene; Dalen, Ingvild; Bergsland, Niels; Farbu, Elisabeth (Journal article; Peer reviewed, 2020)

  Background: Multiple sclerosis is often associated with unemployment. The contribution of grey matter atrophy to unemployment is unclear. Objectives: To identify magnetic resonance imaging biomarkers of grey matter and ...

• Natural Variation of Vitamin D and Neurofilament Light Chain in Relapsing-Remitting Multiple Sclerosis 

  Røsjø, Egil Rørvik; Lindstrøm, Jonas Christoffer; Holmøy, Trygve; Myhr, Kjell-Morten; Varhaug, Kristin Nielsen; Torkildsen, Øivind Fredvik (Journal article; Peer reviewed, 2020-04-30)

  Background: High serum levels of 25-hydroxyvitamin D (25(OH)D) have been found among patients with a favorable disease course in relapsing-remitting MS (RRMS), indicating that this may limit clinical deterioration. Clinical ...

• Meta-analysis and Meta-regression of Survival After Liver Transplantation for Unresectable Perihilar Cholangiocarcinoma 

  Cambridge, William A; Fairfield, Cameron; Powell, James J*; Harrison, Ewen M.; Søreide, Kjetil; Wigmore, Stephen J; Guest, Rachel Victoria (Journal article; Peer reviewed, 2021)

  Objective: To systematically review studies reporting survival data following neoadjuvant chemoradiation and orthotopic liver transplantation (NCR-OLT) for unresectable perihilar cholangiocarcinoma (pCC). Background: ...

• Human seroprevalence of antibodies to tick-borne microbes in southern Norway 

  Thortveit, Erik Thomas; Aase, Audun; Petersen, Lizette Balle; Lorentzen, Åslaug Rudjord; Mygland, Åse; Ljøstad, Unn (Journal article; Peer reviewed, 2020)

  The tick Ixodes ricinus is widespread along the coastline of southern Norway, but data on human exposure to tick-borne microbes are scarce. We aimed to assess the seroprevalence of IgG antibodies to various tick-borne ...

• Difficult birth is the main contributor to birth‐related fracture and accidents to other neonatal fractures 

  Högberg, Ulf; Fellman, Vineta; Thiblin, Ingemar; Karlsson, Ruth; Wester, Knut (Journal article; Peer reviewed, 2020)

  Aim Specific birth-related fractures have been studied; underestimates might be a problem. We aimed to assess all fractures diagnosed as birth-related as well as other neonatal fractures. Methods A population-based ...

• Vurdering av filleristing av barn i straffesaker for norske domstoler 

  Stridbeck, Ulf; Syse, Aslak; Nilsson, Pelle; Wikström, Johan; Wester, Knut (Journal article; Peer reviewed, 2020)

  Dette er en flerfaglig gjennomgang av samtlige norske straffesaker funnet på Lovdata fra 2004 fram til 2015 om «filleristing». Hver sak er gjennomgått av forfatterne; to jurister og tre medisinske eksperter på hodeskader ...

• Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease 

  Flønes, Irene Hana; Ricken, Gerda; Klotz, Sigrid; Lang, Alexandra; Ströbel, Thomas; Dölle, Christian; Kovacs, Gabor G.; Tzoulis, Charalampos (Journal article; Peer reviewed, 2020)

  Mitochondrial dysfunction has been implicated in multiple neurodegenerative diseases but remains largely unexplored in Creutzfeldt-Jakob disease. Here, we characterize the mitochondrial respiratory chain at the individual ...

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