• Folic Acid and Risk of Preterm Birth, Preeclampsia, and Fetal Growth Restriction Among Women With Epilepsy A Prospective Cohort Study 

  Alvestad, Silje; Husebye, Elisabeth Synnøve Nilsen; Christensen, Jakob; Dreier, Julie Werenberg; Sun, Yuelian; Igland, Jannicke; Leinonen, Maarit; Gissler, Mika; Gilhus, Nils Erik; Tomson, Torbjörn; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)

  Background and Objectives Women with epilepsy treated with antiseizure medication (ASM) have increased risk of pregnancy complications including preterm birth, fetal growth restriction, and preeclampsia. We aimed to ...

• What MRI-based tumor size measurement is best for predicting long-term survival in uterine cervical cancer? 

  Lura, Njål Gjærde; Wagner-Larsen, Kari Strøno; Forsse, David Erik; Trovik, Jone; Halle, Mari Kyllesø; Bertelsen, Bjørn; Salvesen, Øyvind; Woie, Kathrine; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022-06-17)

  Background: Tumor size assessment by MRI is central for staging uterine cervical cancer. However, the optimal role of MRI-derived tumor measurements for prognostication is still unclear. Material and methods: This ...

• The personality profile of IPS employment specialists, and how it relates to job satisfaction: A longitudinal cohort study 

  Butenko, Daniil; Rinaldi, Miles; Brinchmann, Beate; Brandseth, Oda Lekve; Killackey, Eoin; Mykletun, Arnstein (Journal article; Peer reviewed, 2022)

  The role of the Individual Placement and Support (IPS) employment specialist is a new type of occupation within mental healthcare. High turnover among employment specialists necessitates improvement in their recruitment ...

• The diagnostic differentiation challenge in acute appendicitis: How to distinguish between uncomplicated and complicated appendicitis in adults 

  Skjold-Ødegaard, Benedicte; Søreide, Kjetil (Journal article; Peer reviewed, 2022-07-15)

  Background: How to best define, diagnose and differentiate uncomplicated from complicated acute appendicitis remains debated. Hence, the aim of this review was to present an overview of the current knowledge and emerging ...

• Role of three dimensional (3D) printing in endourology: An update from EAU young academic urologists (YAU) urolithiasis and endourology working group 

  Hameed, B. M. Zeeshan; Pietropaolo, Amelia; Naik, Nithesh; Noronha, Calvin; Jones, Charles Patrick Warburton; Mykoniatis, Ioannis; Esperto, Francesco; Shah, Milap; Ibrahim, Sufyan; Shetty, Dasharathraj K; Karimi, Hadis; Sharma, Diya; Rai, Bhavan Prasad; Chlosta, Piotr; Somani, Bhaskar K. (Journal article; Peer reviewed, 2022)

  The management of nephrolithiasis has been complemented well by modern technological advancements like virtual reality, three-dimensional (3D) printing etc. In this review, we discuss the applications of 3D printing in ...

• Association of Prenatal Exposure to Antiseizure Medication With Risk of Autism and Intellectual Disability 

  Bjørk, Marte-Helene; Zoega, Helga; Leinonen, Maarit K.; Cohen, Jacqueline Mallory; Dreier, Julie Werenberg; Furu, Kari; Gilhus, Nils Erik; Gissler, Mika; Halfdanarson, Oskar; Igland, Jannicke; Sun, Yuelian; Tomson, Torbjörn; Alvestad, Silje; Christensen, Jakob (Journal article; Peer reviewed, 2022)

  Importance: Women with epilepsy frequently need antiseizure medication (ASM) to prevent seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to AMSs is uncertain. Objective: To determine ...

• Factors Correlated With Physical Function 1 Year After Total Knee Arthroplasty in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis 

  Olsen, Unni; Lindberg, Maren Falch; Rose, Christopher James; Denison, Eva Marie-Louise; Gay, Caryl; Aamodt, Arild; Brox, Jens Ivar; Skare, Øystein; Furnes, Ove Nord; Lee, Kathryn; Lerdal, Anners (Journal article; Peer reviewed, 2022)

  Importance: More than 1 in 5 patients do not experience improved physical function after total knee arthroplasty (TKA). Identification of factors associated with physical function may be warranted to improve outcomes in ...

• Risk factors for revision surgery due to dislocation within 1 year after 111,711 primary total hip arthroplasties from 2005 to 2019: a study from the Norwegian Arthroplasty Register 

  Thoen, Peder Svenkerud; Lygre, Stein Håkon Låstad; Nordsletten, Lars; Furnes, Ove Nord; Stigum, Hein; Hallan, Geir; Röhrl, Stephan Maximillian (Journal article; Peer reviewed, 2022)

  Background and purpose: Dislocation of a hip prosthesis is the 3rd most frequent cause (after loosening and infection) for hip revision in Norway. Recently there has been a shift in surgical practice including preferred ...

• Overactive, aggressive, disruptive and agitated behavior associated with the use of psychotropic medications in schizophrenia 

  Strømme, Maria Fagerbakke; Bartz-Johannessen, Christoffer; Kroken, Rune Andreas; Mehlum, Lars; Johnsen, Erik (Journal article; Peer reviewed, 2022)

  Background Evidence is limited for the associations between use of psychotropic medications and overactive, aggressive, disruptive or agitated behavior (OADA)1 in clinical practice. Aims To investigate the associations ...

• Sixteen-week multicentre randomised controlled trial to study the effect of the consumption of an oat beta-glucanenriched bread versus a whole-grain wheat bread on glycaemic control among persons with pre-diabetes: a study protocol of the CarbHealth study 

  Hjorth, Therese; Schadow, Alena; Revheim, Ingrid; Spielau, Ulrike; Thomassen, Lise M.; Meyer, Klara; Piotrowski, Katja; Rosendahl-Riise, Hanne; Rieder, Anne; Varela, Paula; Lysne, Vegard; Ballance, Simon; Koerner, Antje; Landberg, Rikard; Buyken, Anette E.; Dierkes, Jutta (Journal article; Peer reviewed, 2022)

  Introduction In 2012, the estimated global prevalence of pre-diabetes was 280 million, and the prevalence is expected to rise to 400 million by 2030. Oat-based foods are a good source of beta-glucans, which have been ...

• A multilevel, step-based model to evaluate progress in procedure efficiency for laparoscopic appendicectomy in surgical training: structured evaluation using 'ebb-and-flow' and 'string-of-pearls' concepts 

  Søreide, Kjetil; Skjold-Ødegaard, Benedicte (Journal article; Peer reviewed, 2022)

  Background Surgical training is aimed towards entrusted professional activity to obtain operative independence. Laparoscopic appendicectomy is performed early in training but except for simulators, real-life evaluation ...

• Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery 

  Kotopoulis, Spiros; Lam, Christina; Haugse, Ragnhild; Snipstad, Sofie; Murvold, Elsa Thodesen; Jouleh, Tæraneh; Berg, Sigrid; Hansen, Rune; Popa, Mihaela-Lucia; Mccormack, Emmet Matin; Gilja, Odd Helge; Poortinga, Albert (Journal article; Peer reviewed, 2022)

  The aim of this study was to develop high load-capacity antibubbles that can be visualized using diagnostic ultrasound and the encapsulated drug can be released and delivered using clinically translatable ultrasound. The ...

• Impact of childhood trauma on antipsychotic effectiveness in schizophrenia spectrum disorders: A prospective, pragmatic, semi-randomized trial 

  Mørkved, Nina; Johnsen, Erik; Kroken, Rune Andreas; Winje, Dagfinn; Larsen, Tor Ketil; Thimm, Jens; Rettenbacher, M.A.; Johannesen, C.A. Bartz; Løberg, Else-Marie (Journal article; Peer reviewed, 2022)

  Antipsychotic medications are generally effective in ameliorating psychotic symptoms in schizophrenia spectrum disorders (SSDs). Identifying predictors associated with poor treatment response is important for a personalized ...

• Characteristics and fate of patients with rectal cancer not entering a curative-intent treatment pathway: A complete nationwide registry cohort of 3,304 patients 

  Kørner, Hartwig; Guren, Marianne; Larsen, Inger Kristin; Haugen, Dagny Renata Faksvåg; Søreide, Kjetil; Kørner, Leif Roland; Søreide, Jon Arne (Journal article; Peer reviewed, 2022)

  Background: Treatment options for advanced and metastatic rectal cancer have increased during the past decades. However, a considerable proportion of the patients are not eligible for curative treatment, and data on this ...

• Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, noninferiority, double-blinded, randomised and placebocontrolled trial 

  Solheim, Anne Marit; Lorentzen, Åslaug Rudjord; Dahlberg, Audun Olav; Flemmen, Heidi Øyen; Brune, Synne; Forselv, Kristine Johanne Nordstrøm; Pripp, Are Hugo; Bø, Margrete Halvorsen; Eikeland, Randi; Reiso, Harald; Mygland, Åse Daasvand; Ljøstad, Unn (Journal article; Peer reviewed, 2022)

  Background There is limited evidence regarding optimal duration of antibiotic treatment in neuroborreliosis. We aimed to compare efficacy and safety of oral doxycycline for 2 and 6 weeks in European Lyme neuroborreliosis ...

• Pharmacological evaluation of the effects of enzymatically liberated fish oil on eosinophilic inflammation in animal models 

  Currie, Crawford; Framroze, Bomi; Singh, Dave; Sharma, Deepali; Bjerknes, Christian; Hermansen, Erland (Journal article; Peer reviewed, 2022)

  The inappropriate activation of eosinophils is a well-recognized driver of various human inflammatory diseases including asthma, chronic rhinitis, and various gastrointestinal diseases, including eosinophilic esophagitis. ...

• Incidence, Mechanisms of Injury and Mortality of Severe Traumatic Brain Injury: An Observational Population-Based Cohort Study from New Zealand and Norway 

  Weber, Clemens; Andreassen, Joakim Stray; Isles, Siobhan; Thorsen, Kenneth; McBride, Paul; Søreide, Kjetil; Civil, Ian (Journal article; Peer reviewed, 2022)

  Background Comparing trauma registry data from different countries can help to identify possible differences in epidemiology, which may help to improve the care of trauma patients. Methods This study directly compares ...

• Serum neurofilament as a predictor of 10-year grey matter atrophy and clinical disability in multiple sclerosis: a longitudinal study 

  Lie, Ingrid Anne; Kacar, Sezgi; Wesnes, Kristin; Brouwer, Iman; Kvistad, Silje S.; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne-Cathrin Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Varhaug, Kristin Nielsen; Vedeler, Christian Alexander; Barkhof, Frederik; Teunissen, Charlotte E.; Bø, Lars; Torkildsen, Øivind Fredvik Grytten; Myhr, Kjell-Morten; Vrenken, Hugo (Journal article; Peer reviewed, 2022)

  Background The predictive value of serum neurofilament light chain (sNfL) on long-term prognosis in multiple sclerosis (MS) is still unclear. Objective Investigate the relation between sNfL levels over a 2-year ...

• Who gets the ventilator? A multicentre survey of intensivists' opinions of triage during the first wave of the COVID-19 pandemic 

  Fjølner, Jesper; Haaland, Øystein Ariansen; Jung, Christian; de Lange, Dylan W.; Szczeklik, Wojciech; Leaver, Susannah; Guidet, Bertrand; Sviri, Sigal; Van Heerden, Peter Vernon; Beil, Michael; Hartog, Christiane S.; Flaatten, Hans Kristian (Journal article; Peer reviewed, 2022)

  Background The COVID-19 pandemic has caused a shortage of intensive care resources. Intensivists' opinion of triage and ventilator allocation during the COVID-19 pandemic is not well described. Methods This was a ...

• Advances in Ureteroscopy: New technologies and current innovations in the era of Tailored Endourological Stone Treatment (TEST) 

  Juliebø-Jones, Patrick; Keller, Etienne Xavier; Haugland, Julie Nøss; Æsøy, Mathias S.; Beisland, Christian; Somani, Bhaskar K; Ulvik, Øyvind (Journal article; Peer reviewed, 2022)

  Ureteroscopy has undergone many advances in recent decades. As a result, it is able to treat an increasing range of patient groups including special populations such as pregnancy, anomalous kidneys and extremes of age. ...

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