• Disease-Course Adapting Machine Learning Prognostication Models in Elderly Patients Critically Ill With COVID-19: Multicenter Cohort Study With External Validation 

  Jung, Christian; Mamandipoor, Behrooz; Fjølner, Jesper; Bruno, Raphael Romano; Wernly, Bernhard; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter V.; Szczeklik, Wojciech; Czuczwar, Miroslaw; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans Kristian; Osmani, Venet (Journal article; Peer reviewed, 2022)

  Background:The COVID-19 pandemic caused by SARS-CoV-2 is challenging health care systems globally. The disease disproportionately affects the elderly population, both in terms of disease severity and mortality risk. ...

• The effect of gadolinium-based contrast-agents on automated brain atrophy measurements by FreeSurfer in patients with multiple sclerosis 

  Lie, Ingrid Anne; Kerklingh, Emma; Wesnes, Kristin; van Nederpelt, David R.; Brouwer, Iman; Torkildsen, Øivind; Myhr, Kjell-Morten; Barkhof, Frederik; Bø, Lars; Vrenken, Hugo (Journal article; Peer reviewed, 2022)

  Objective To determine whether reliable brain atrophy measures can be obtained from post-contrast 3D T1-weighted images in patients with multiple sclerosis (MS) using FreeSurfer. Methods Twenty-two patients with MS ...

• In-office thermal systems for the treatment of dry eye disease 

  Beining, Marie Wangen; Magnø, Morten Scherven; Moschowits, Emily; Olafsson, Jonatan; Vehof, Jelle; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2022)

  Dry eye disease affects millions of people worldwide, causing pain, vision disturbance, and reduced productivity. Meibomian gland dysfunction, a major cause of dry eye, is characterized by chronic glandular inflammation, ...

• Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction 

  Mundal, Siv Boon; Rakner, Johanne Johnsen; Silva, Gabriela; Gierman, Lobke; Austdal, Marie; Basnet, Purusotam; Elschot, Mattijs; Bakke, Siril Skaret; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Moses, Eric; Acharya, Ganesh; Bjørge, Line; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2022)

  Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are ...

• Vagally mediated heart rate variability, stress, and perceived social support: a focus on sex differences 

  Kvadsheim, Elisabet; Sørensen, Lin; Fasmer, Ole Bernt; Osnes, Berge; Haavik, Jan; Williams, DeWayne P.; Thayer, Julian Francis; Koenig, Julian (Journal article; Peer reviewed, 2022)

  Higher vagally mediated heart rate variability (vmHRV), reflecting vagal activity as indexed by heart function and lower stress vulnerability, is associated with higher perceived social support. Seeking social support is ...

• Thulium Fibre Laser versus Holmium:YAG for Ureteroscopic Lithotripsy: Outcomes from a Prospective Randomised Clinical Trial 

  Ulvik, Øyvind; Æsøy, Mathias S.; Jones, Charles Patrick Warburton; Gjengstø, Peder; Beisland, Christian (Journal article; Peer reviewed, 2022)

  Background Holmium:yttrium-aluminium-garnet (Ho:YAG) laser is the gold standard for ureterorenoscopic (URS) lithotripsy. Thulium fibre laser (TFL) has recently been introduced as a new technology and may challenge Ho:YAG ...

• Development and feasibility testing of a physical activity intervention for youth with anxiety and depression: a study protocol 

  Kodal, Arne; Muirhead, Fiona; Reilly, John J.; Wergeland, Gro Janne Henningsen; Thorsen, Paul Joachim Bloch; Bovim, Lars Peder Vatshelle; Elgen, Irene Bircow (Journal article; Peer reviewed, 2022)

  Background Anxiety and depressive disorders in children and adolescents are highly prevalent and account for more than half of all youth psychiatric disorders. Left untreated, anxiety, and depression lead to numerous ...

• Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases 

  Jellas, Khadija el; Dušátková, Petra; Haldorsen, Ingfrid S.; Molnes, Janne; Tjora, Erling; Johansson, Bente Berg; Fjeld, Karianne; Johansson, Stefan; Průhová, Štěpánka; Groop, Leif; Löhr, J. Matthias; Njølstad, Pål Rasmus; Molven, Anders (Journal article; Peer reviewed, 2022)

  Context Maturity onset diabetes of the young, type 8 (MODY8) is associated with mutations in the CEL gene, which encodes the digestive enzyme carboxyl ester lipase. Several diabetes cases and families have in recent years ...

• Salmon Protein Hydrolysate Potentiates the Growth Inhibitory Effect of Bicalutamide on Human Prostate Cancer Cell Lines LNCaP and PC3 by Modulating Iron Homeostasis 

  Bjerknes, Christian; Framroze, Bomi; Currie, Crawford; Pettersen, Caroline Hild; Axcrona, Karol; Hermansen, Erland (Journal article; Peer reviewed, 2022)

  Prostate cancer is a common cause of cancer death in men. In advanced stages of prostate cancer, androgen deprivation therapy (ADT) is initiated. Despite ADT, prostate cancers invariably progress to become androgen ...

• Variability and similarity of inter-beat intervals of the heart as markers of perceived stress and behavioral regulation 

  Kvadsheim, Elisabet (Doctoral thesis, 2022-08-16)

  The current dissertation investigated inter-beat interval (IBI) indices of variability and similarity, reflecting autonomic nervous system (ANS) modulation on heart rate. IBI indices of cardiac vagal activity (CVA) are ...

• Dynamics of Plasma and Urinary Extracellular DNA in Acute Kidney Injury 

  Jančuška, Alexander; Potočárová, Alena; Kovalčíková, Alexandra Gaál; Podracká, L’Udmila; Babickova, Janka; Celec, Peter; Tóthová, L’Ubomíra (Journal article; Peer reviewed, 2022)

  Early and reliable markers of acute kidney injury (AKI) are essential. One such candidate marker of tissue damage is extracellular DNA (ecDNA). The aim of our present study is to describe the unknown dynamics of ecDNA in ...

• Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures 

  Gonzalez, Alba; Haugaa, Kristina Ingrid Helena Hermann; Brekke, Pål Haugar; Hopp, Einar; Ørn, Stein; Alvestad, Silje; Taubøll, Erik; Aurlien, Dag (Journal article; Peer reviewed, 2022)

  High frequency of convulsive seizures and long-lasting epilepsy are associated with an increased risk of sudden unexpected death in epilepsy (SUDEP). Structural changes in the myocardium have been described in SUDEP victims. ...

• Irritable bowel syndrome patients who are not likely to respond to fecal microbiota transplantation 

  El-Salhy, Magdy; Mazzawi, Tarek; Hausken, Trygve; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2022)

  Background Fecal microbiota transplantation (FMT) interventions have recently been advocated to not succeed in every irritable bowel syndrome (IBS) patient, since the outcome of FMT varies with the IBS subset. This study ...

• Length of hospital stay and risk of intensive care admission and in-hospital death among COVID-19 patients in Norway: a register-based cohort study comparing patients fully vaccinated with an mRNA vaccine to unvaccinated patients 

  Whittaker, Robert Neil; Kristoffersen, Anja Bråthen; Valcarcel Salamanca, Beatriz; Seppälä, Elina Marjukka; Samareh Golestani, Karan; Kvåle, Reidar; Watle, Sara Sofie Viksmoen; Buanes, Eirik Alnes (Journal article; Peer reviewed, 2022)

  Objectives We estimated the length of stay (LoS) in hospital and the intensive care unit (ICU) and risk of admission to ICU and in-hospital death among COVID-19 patients ≥18 years in Norway who had been fully vaccinated ...

• Early screening outcomes among non-immigrants and immigrants targeted by BreastScreen Norway, 2010–2019 

  Thy, Jonas Evensen; Bhargava, Sameer; Larsen, Marthe; Akslen, Lars Andreas; Hofvind, Solveig Sand-Hanssen (Journal article; Peer reviewed, 2022)

  Aims: This study aimed to analyse results on early screening outcomes, including recall and cancer rates, and histopathological tumour characteristics among non-immigrants and immigrants invited to BreastScreen ...

• Exploring variables affecting sense of coherence and social support in recovery after colorectal cancer surgery among the oldest old 

  Eriksen, Kristina Sundt; Lode, Kirsten; Husebø, Sissel Iren Eikeland; Kørner, Hartwig (Journal article; Peer reviewed, 2022)

  Objective To explore the associations between sense of coherence, perceived social support, and demographic and clinical characteristics among survivors ≥80 years treated for curable colorectal cancer. Methods This ...

• Podocan and Adverse Clinical Outcome in Patients Admitted With Suspected Acute Coronary Syndromes 

  Andersen, Thomas; Ueland, Thor; Aukrust, Pål; Nilsen, Dennis W.T.; Grundt, Magnea Heidi Jonsdottir; Staines, Harry; Kontny, Frederic (Journal article; Peer reviewed, 2022)

  Background: Markers of bone and extracellular matrix (ECM) remodeling may be associated with adverse outcomes in atherosclerotic cardiovascular disease. Podocan is a newly discovered ECM glycoprotein, previously not studied ...

• Geographical variation in ADHD: do diagnoses refect symptom levels? 

  Widding-Havneraas, Tarjei; Markussen, Simen; Elwert, Felix; Lyhmann, Ingvild; Bjelland, Ingvar; Halmøy, Anne; Chaulagain, Ashmita; Ystrøm, Eivind; Mykletun, Arnstein; Zachrisson, Henrik Daae (Journal article; Peer reviewed, 2022)

  Rates of ADHD diagnosis vary across regions in many countries. However, no prior study has investigated how much within-country geographic variation in ADHD diagnoses is explained by variation in ADHD symptom levels. We ...

• Akathisia and atypical antipsychotics. Relation to suicidality, agitation and depression in a clinical trial 

  Bjarke, Jill Kristin; Gjerde, Helga Nødland; Jørgensen, Hugo A; Kroken, Rune Andreas; Løberg, Else-Marie; Johnsen, Erik (Journal article; Peer reviewed, 2022)

  Objective: Akathisia is among the most unpleasant side effects related to antipsychotic drug (AP) use, and possible associations between akathisia and agitation, depression and suicidal behaviour, respectively, have been ...

• Cognitive function in patients with neuroborreliosis: A prospective cohort study from the acute phase to 12 months post treatment 

  Andreassen, Silje; Solheim, Anne Marit; Ljøstad, Unn; Mygland, Åse Daasvand; Lorentzen, Åslaug Rudjord; Reiso, Harald; Beyer, Mona Kristiansen; Harbo, Hanne-Cathrin Flinstad; Løhaugen, Gro; Eikeland, Randi (Journal article; Peer reviewed, 2022)

  Background Long-term cognitive problems after neuroborreliosis treatment remain a subject of debate. We have previously shown that cognitive problems are not present in the acute phase of neuroborreliosis, although fatigue ...

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