Browsing Department of Clinical Medicine by Title
Now showing items 1-20 of 2198
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An 18-Gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer
(Peer reviewed; Journal article, 2014-06-06)Aims: Vascular invasion by tumor cells is known to be important for cancer progression. By microarray and qPCR analyses, we earlier identified an 18-gene signature associated with vascular involvement in endometrial cancer. ... -
25-year results after anterior cruciate ligament reconstruction with the use of a patellar tendon autograft
(Doctoral thesis, 2022-06-17)Background: Only a few studies of ACL reconstruction with >20 years of follow-up exists. It is still a pause in the literature concerning the patient’s further sports participation and long-term subjective and objective ... -
A 3-D post-mortem model provides rationale for complications in gastrointestinal surgery : a post-mortem corrosion-cast model
(Doctoral thesis, 2007-06-08) -
A 60-year follow-up of the incidence and prevalence of multiple sclerosis in Hordaland County, Western Norway
(Peer reviewed; Journal article, 2015-01-14)Objective: Investigate the incidence of multiple sclerosis during 1953–2013 and estimate the prevalence rate of MS on 1 January 2003 and 2013 in Hordaland County, Western Norway. Methods: All patients with onset of disease ... -
Abnormal Uroguanylin Immunoreactive Cells Density in the Duodenum of Patients with Diarrhea-Predominant Irritable Bowel Syndrome Changes following Fecal Microbiota Transplantation
(Journal article; Peer reviewed, 2020)Altered densities of enteroendocrine cells play an important role in patients with irritable bowel syndrome (IBS). Uroguanylin activates guanylate cyclase-C to regulate intestinal electrolyte and water transport. Aim. To ... -
An Abrupt Transition to Digital Teaching—Norwegian Medical Students and Their Experiences of Learning Output during the Initial Phase of the COVID-19 Lockdown
(Journal article; Peer reviewed, 2022)Norwegian universities closed almost all on-campus activities on the 12 March 2020 following a lockdown decision of the Norwegian government in response to the COVID-19 pandemic. Online and digital teaching became the ... -
Abstract book : 20th Anniversary Symposium of National Centre for Ultrasound in Gastroenterology
(Book of abstracts, 2021) -
Abuse and revictimization in adulthood in multiple sclerosis: a cross-sectional study during pregnancy
(Journal article; Peer reviewed, 2022)Background: Knowledge concerning exposure to abuse in adulthood and in pregnancy in people with multiple sclerosis (MS) is sparse. Objective: To determine the occurrence of adult abuse and abuse in relation to pregnancy ... -
Accounting for NAD Concentrations in Genome-Scale Metabolic Models Captures Important Metabolic Alterations in NAD-Depleted Systems
(Journal article; Peer reviewed, 2024)Nicotinamide adenine dinucleotide (NAD) is a ubiquitous molecule found within all cells, acting as a crucial coenzyme in numerous metabolic reactions. It plays a vital role in energy metabolism, cellular signaling, and DNA ... -
Accounting for symptom heterogeneity can improve neuroimaging models of antidepressant response after electroconvulsive therapy
(Journal article; Peer reviewed, 2021)Depression symptom heterogeneity limits the identifiability of treatment-response biomarkers. Whether improvement along dimensions of depressive symptoms relates to separable neural networks remains poorly understood. We ... -
Accumulation dynamics of transcripts and proteins of cold-responsive genes in fragaria vesca genotypes of differing cold tolerance
(Journal article; Peer reviewed, 2021)Identifying and characterizing cold responsive genes in Fragaria vesca associated with or responsible for low temperature tolerance is a vital part of strawberry cultivar development. In this study we have investigated the ... -
Accumulation of Globotriaosylceramide in Podocytes in Fabry Nephropathy Is Associated with Progressive Podocyte Loss
(Journal article; Peer reviewed, 2020)Background In males with classic Fabry disease, the processes leading to the frequent outcome of ESKD are poorly understood. Defects in the gene encoding α-galactosidase A lead to accumulation of globotriaosylceramide (GL3) ... -
Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
(Journal article; Peer reviewed, 2023)Current therapies for Fabry disease are based on reversing intracellular accumulation of globotriaosylceramide (Gb3) by enzyme replacement therapy (ERT) or chaperone-mediated stabilization of the defective enzyme, thereby ... -
Accuracy of single intravenous access iohexol GFR in children is hampered by marker contamination
(Journal article; Peer reviewed, 2021)Measurement of glomerular filtration rate (GFR) in children by iohexol injection and blood sampling from the contralateral arm is widely used. A single intravenous access for iohexol injection and subsequent blood sampling ... -
Accuracy of surgical complication rate estimation using ICD-10 codes
(Peer reviewed; Journal article, 2019-02)Background: The ICD‐10 codes are used globally for comparison of diagnoses and complications, and are an important tool for the development of patient safety, healthcare policies and the health economy. The aim of this ... -
AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study
(Journal article; Peer reviewed, 2020-07-08)Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor degradation, ... -
ACL Reconstruction Patients Have Increased Risk of Knee Arthroplasty at 15 Years of Follow-up : Data from the Norwegian Knee Ligament Register and the Norwegian Arthroplasty Register from 2004 to 2020
(Journal article; Peer reviewed, 2022)Background: Anterior cruciate ligament (ACL) injury is considered a risk factor for osteoarthritis. The primary aim of the present study was to investigate the cumulative risk of, and risk factors associated with, a ... -
Actigraphic assessment of motor activity in acutely admitted inpatients with bipolar disorder
(Peer reviewed; Journal article, 2014-02-20)Introduction: Mania is associated with increased activity, whereas psychomotor retardation is often found in bipolar depression. Actigraphy is a promising tool for monitoring phase shifts and changes following treatment ... -
Actigraphic registration of motor activity reveals a more structured behavioural pattern in schizophrenia than in major depression
(Peer reviewed; Journal article, 2010-05-27)Background: Disturbances in motor activity pattern are seen in both schizophrenia and depression. However, this activity has rarely been studied objectively. The purpose of the present study has been to study the complexity ... -
Actigraphy as an objective intra‑individual marker of activity patterns in acute‑phase bipolar disorder: a case series
(Peer reviewed; Journal article, 2018-03-07)Background: Actigraphy could be an objective alternative to clinical ratings of motor activity in bipolar disorder (BD), which is of importance now that increased activity and energy are added as cardinal symptoms of ...