Department of Clinical Medicine
Nye registreringer
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Sjögren’s Syndrome: The Role of Serological Profiles Versus Minor Salivary Gland Histopathology
(Journal article; Peer reviewed, 2024)Between the years 2008 and 2023, 306 patients were referred to the Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, University of Oslo, for salivary gland biopsy after clinical suspicion of Sjögren’s ... -
Amyotrophic lateral sclerosis caused by the C9orf72 expansion in Norway–prevalence, ancestry, clinical characteristics and sociodemographic status
(Journal article; Peer reviewed, 2025)Objective: The most common genetic cause of amyotrophic lateral sclerosis (ALS) is the C9orf72 expansion. A high incidence of this expansion has been detected in Sweden and Finland. This Norwegian population-based study ... -
Increased risk of rehospitalisation and death in older hospital patients at risk of malnutrition: A cohort study
(Journal article; Peer reviewed, 2024)Objectives The aim of the study was to investigate associations between risk of malnutrition and risk of rehospitalisation and death in older hospital patients, and whether the possible associations were modified by age, ... -
Identification and characterization of migraine in pregnancy: A Norwegian registry-based cohort study
(Journal article; Peer reviewed, 2024)Background Migraine is common in women of reproductive age. Migraine’s episodic manifestation and acute and preventive pharmacological treatment options challenge studying drug safety for this condition during pregnancy. ... -
Low maternal iodine intake and subsequent risk of pharmacologically treated hypertension: A population-based prospective cohort study
(Journal article; Peer reviewed, 2025)Background & aims Iodine deficiency is linked to multiple adverse health outcomes, but there is scarce knowledge regarding iodine intake and development of chronic hypertension. We aimed to investigate the prospective ... -
Bacterial growth in patients with low back pain and Modic changes: protocol of a multicentre, case–control biopsy study
(Journal article; Peer reviewed, 2024)Introduction Bacterial infection and Modic changes (MCs) as causes of low back pain (LBP) are debated. Results diverged between two randomised controlled trials examining the effect of amoxicillin with and without clavulanic ... -
Long-term clinical recovery and treatment resistance in first-episode psychosis: a 10-year follow-up study
(Journal article; Peer reviewed, 2024)Illness trajectories in people with first-episode psychosis (FEP) vary significantly over time. Identifying early-course parameters predicting outcomes is essential, but long-term data still needs to be provided. We conducted ... -
Utility and limitations of EEG in the diagnosis and management of ALDH7A1-related pyridoxine-dependent epilepsy. A retrospective observational study
(Journal article; Peer reviewed, 2024)Purpose: Pyridoxine-dependent epilepsy due to ALDH7A1 variants (PDE-ALDH7A1) is a rare disorder, presenting typically with severe neonatal, epileptic encephalopathy. Early diagnosis is imperative to prevent uncontrolled ... -
Impact of diabetes on the risk of subsequent fractures in 92,600 patients with an incident hip fracture: A Danish nationwide cohort study 2004–2018
(Journal article; Peer reviewed, 2024)Purpose We investigated the incidence rates of a subsequent hip fracture (HF) and other subsequent fractures than HF after first incident HF, comparing patients with and without diabetes. Methods Using Danish medical ... -
Influence of design features and brand of reverse shoulder arthroplasties on survivorship and reasons for revision surgery: results of 5,494 arthroplasties with up to 15 years’ follow-up reported to the Norwegian Arthroplasty Register 2007–2022
(Journal article; Peer reviewed, 2024)Background and purpose: We aimed to report the survival of different reverse shoulder arthroplasty (RSA) designs and brands, and factors associated with revision. The secondary aim was to evaluate the reasons for ... -
The STRAT-PARK cohort: A personalized initiative to stratify Parkinson's disease
(Journal article; Peer reviewed, 2024)The STRAT-PARK initiative aims to provide a platform for stratifying Parkinson’s disease (PD) into biological subtypes, using a bottom-up, multidisciplinary biomarker-based and data-driven approach. PD is a heterogeneous ... -
Electroconvulsive therapy and cognitive performance from the Global ECT MRI Research Collaboration
(Journal article; Peer reviewed, 2024)The Global ECT MRI Research Collaboration (GEMRIC) has collected clinical and neuroimaging data of patients treated with electroconvulsive therapy (ECT) from around the world. Results to date have focused on neuroimaging ... -
Characterization of gray matter volume changes from one week to 6 months after termination of electroconvulsive therapy in depressed patients
(Journal article; Peer reviewed, 2024)Background Increased gray matter volume (GMV) following electroconvulsive therapy (ECT) has been well-documented, with limited studies reporting a subsequent decrease in GMV afterwards. Objective This study characterized ... -
Increased expression of CXCL10 and CCL3 salivary gland chemokines in primary Sjögren's syndrome detected and systematically quantified using novel RNAscope® in situ hybridisation
(Journal article; Peer reviewed, 2025)Primary Sjögren’s syndrome is a chronic inflammatory disease characterized by the destruction of exocrine glands. We have previously shown significantly upregulated levels of CXCL10 and CCL3 chemokines in saliva from ... -
The Food Sources in Western Diets Modulate Obesity Development, Insulin Sensitivity, and the Plasma and Cecal Metabolome in Mice
(Journal article; Peer reviewed, 2024)Scope Dietary constituents modulate development of obesity and type 2 diabetes. The metabolic impact from different food sources in western diets (WD) on obesity development is not fully elucidated. This study aims to ... -
Identification and characterization of a novel gene associated with hereditary retinal disorder(s)
(Doctoral thesis, 2025-04-09)Bakgrunn: Retinitis pigmentosa (RP) er kjent som den vanligst forekommende arvelige retinale dystrofi med en prevalens på nesten 1:4000 på verdensbasis. RP skyldes i utgangspunktet tap av stav fotoreseptorer, ledsaget av ... -
Understanding Dementia Speech: Towards an Adaptive Voice Assistant for Enhanced Communication
(Chapter, 2024)Dementia poses significant challenges to individuals, particularly those grappling with Alzheimer’s disease, impacting their daily lives, well-being, and communication. The task of enhancing communication for People with ... -
Determinants of non-adherence to antibiotic treatment guidelines in hospitalized adults with suspected community-acquired pneumonia: a prospective study
(Journal article; Peer reviewed, 2024)Background Antimicrobial resistance (AMR) is a global health threat with millions of deaths annually attributable to bacterial resistance. Effective antimicrobial stewardship programs are crucial for optimizing antibiotic ... -
Gastrointestinal hormones and subjective ratings of appetite after low-carbohydrate vs low-fat low-energy diets in females with lipedema - A randomized controlled trial
(Journal article; Peer reviewed, 2024)Background Ketosis seems to attenuate, or prevent, the rise in both ghrelin concentrations and subjective hunger ratings that follow weight loss. However, most of the previous studies have employed very-low energy diets ... -
Primary and revision artificial urinary sphincter for stress urinary incontinence post-radical prostatectomy: a surgery with high rewards but high risks?
(Journal article; Peer reviewed, 2024)Objectives: To evaluate the efficacy of artificial urinary sphincter (AUS) implantation in men with stress urinary incontinence post-radical prostatectomy and the complication burden with a focus on identifying potential ...
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