• Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies 

  Wang, Heling; Siow, Richard; Schmauck-Medina, Tomás Alejandro; Zhang, Jianying; Sandset, Per Morten; Filshie, Clare; Lund, Øystein; Partridge, Linda; Bergersen, Linda Hildegard; Juel Rasmussen, Lene; Palikaras, Konstantinos; Sotiropoulos, Ioannis; Storm-Mathisen, Jon; Rubinsztein, David C.; Spillantini, Maria Grazia; De Zeeuw, Chris I.; Watne, Leiv; Vyhnalek, Martin; Veverova, Katerina; Liang, Xiao; Tavernarakis, Nektarios; Bohr, Vilhelm A.; Yokote, Koutaro; Saarela, Janna Saija; Nilsen, Hilde; Gonos, Efstathios S.; Scheibye-Knudsen, Morten; Chen, Guobing; Kato, Hisaya; Selbæk, Geir; Fladby, Tormod; Nilsson, Per; Simonsen, Anne Gjøen; Aarsland, Dag; Hindkjær Lautrup, Sofie; Ottersen, Ole Petter; Cox, Lynne S.; Fang, Fei (Journal article; Peer reviewed, 2024)

  Unhealthy aging poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the aging process offers a promising approach to reduce the burden of a number of age-related diseases, such ...

• Repeat expansions in AR, ATXN1, ATXN2 and HTT in Norwegian patients diagnosed with amyotrophic lateral sclerosis 

  Novy, Camilla; Busk, Øyvind; Tysnes, Ole-Bjørn; Landa, Sigve Strand; Aanjesen, Tori Navestad; Alstadhaug, Karl Bjørnar; Bjerknes, Tale Litlere; Bjørnå, Ingrid Kristine; Bråthen, Geir; Dahl, Elin; Demic, Natasha; Fahlström, Maria; Flemmen, Heidi Øyen; Hallerstig, Erika Carina; HogenEsch, Ineke; Kampman, Margitta; Kleveland, Grethe; Kvernmo, Helene Ballo; Ljøstad, Unn; Maniaol, Angelina; Morsund, Aase Hagen; Nakken, Ola; Olsen, Cathrine Goberg; Schlüter, Katrin Ruth; Utvik, May-Sissel; Yaseen, Ryaz; Holla, Øystein Lunde; Holmøy, Trygve; Høyer, Helle (Journal article; Peer reviewed, 2024)

  Genetic repeat expansions cause neuronal degeneration in amyotrophic lateral sclerosis as well as other neurodegenerative disorders such as spinocerebellar ataxia, Huntington’s disease and Kennedy’s disease. Repeat expansions ...

• Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease 

  Gonzalez-Ortiz, Fernando; Kirsebom, Bjørn-Eivind Seljelid; Contador, José; Tanley, Jordan E.; Selnes, Per; Gisladottir, Berglind; Pålhaugen, Lene; Hemminghyth, Mathilde Suhr; Jarholm, Jonas Alexander; Skogseth, Ragnhild Eide; Bråthen, Geir; Grøndtvedt, Gøril; Bjørnerud, Atle; Tecelao, Sandra; Waterloo, Knut; Aarsland, Dag; Fernández-Lebrero, Aida; García-Escobar, Greta; Navalpotro-Gómez, Irene; Turton, Michael; Hesthamar, Agnes; Kac, Przemyslaw R.; Nilsson, Johanna; Luchsinger, Jose; Hayden, Kathleen M.; Harrison, Peter; Puig-Pijoan, Albert; Zetterberg, Henrik; Hughes, Timothy M.; Suárez-Calvet, Marc; Karikari, Thomas K.; Fladby, Tormod; Blennow, Kaj (Journal article; Peer reviewed, 2024)

  Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-tau) associates ...

• Fecal bacteria and short-chain fatty acids in irritable bowel syndrome: relations to subtype 

  Teige, Erica Sande; Hillestad, Eline; Steinsvik, Elisabeth Kjelsvik; Brønstad, Ingeborg; Lundervold, Arvid; Lundervold, Astri J.; Valeur, Jørgen; Hausken, Trygve; Jacobsen, Birgitte Berentsen; Lied, Gülen Arslan (Journal article; Peer reviewed, 2024)

  Background: The relationship between gut microbiota and irritable bowel syndrome (IBS) subtype is unclear. We aimed to explore whether differences in fecal bacteria composition and short-chain fatty acid (SCFA) levels were ...

• Preoperative fatty infiltration of paraspinal muscles assessed by MRI is associated with less improvement of leg pain 2 years after surgery for lumbar spinal stenosis 

  Banitalebi, Hasan; Hermansen, Erland; Hellum, Christian; Espeland, Ansgar; Storheim, Kjersti; Myklebust, Tor Åge; Indrekvam, Kari; Brisby, Helena; Weber, Clemens; Anvar, Masoud; Aaen, Jørn Ståle; Negård, Anne (Journal article; Peer reviewed, 2024)

  Abstract Purpose Fatty infiltration (FI) of the paraspinal muscles may associate with pain and surgical complications in patients with lumbar spinal stenosis (LSS). We evaluated the prognostic influence of MRI-assessed ...

• The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers' Disease 

  Hong, Yu; Zhang, Zhuoyuan; Yangzom, Tsering; Chen, Anbin; Lundberg, Bjørn Christian; Fang, Fei; Siller, Richard; Sullivan, Gareth John; Zeman, Jiri; Tzoulis, Charalampos; Bindoff, Laurence Albert; Liang, Xiao (Journal article; Peer reviewed, 2024)

  Alpers' syndrome is an early-onset neurodegenerative disorder usually caused by biallelic pathogenic variants in the gene encoding the catalytic subunit of polymerase-gamma (POLG), which is essential for mitochondrial DNA ...

• Previous cartilage surgery is associated with inferior patient-reported outcomes after knee arthroplasty 

  Birkenes, Thomas; Furnes, Ove Nord; Lygre, Stein Håkon Låstad; Solheim, Eirik Johan; Årøen, Asbjørn; Knutsen, Gunnar; Drogset, Jon Olav; Heir, Stig; Engebretsen, Lars; Løken, Sverre Bertrand; Visnes, Håvard (Journal article; Peer reviewed, 2024)

  Purpose: The hypothesis of the present study assumed that a history of focal cartilage lesions would not affect Knee Injury and Osteoarthritis Outcome scores (KOOSs) following knee arthroplasty compared to a matched national ...

• Feasibility of a physical activity intervention for children and adolescents with anxiety and depression 

  Kodal, Arne; Muirhead, Fiona; Reilly, John J.; Wergeland, Gro Janne Henningsen; Thorsen, Paul Joachim Bloch; Bovim, Lars Peder Vatshelle; Elgen, Irene Bircow (Journal article; Peer reviewed, 2024-03-05)

  Background: Physical activity is identified as a key modifiable factor towards good short- and long-term mental health and has shown positive effects on anxiety and depression in children and adolescents. However, physical ...

• Behavioral Inhibition and Social Anxiety Disorder as Predictors of Long-Term Outcomes of Cognitive Behavioral Therapy for Youth Anxiety Disorders 

  Skumsnes, Toril; Fjermestad, Krister Westlye; Wergeland, Gro Janne Henningsen; Aalberg, Marianne; Heiervang, Einar Røshol; Kodal, Arne; Ingul, Jo Magne (Journal article; Peer reviewed, 2024)

  The temperamental trait behavioral inhibition (BI) is related to the development and maintenance of anxiety, particularly much so to social anxiety disorder. We investigated if BI and social anxiety disorder predicted ...

• Impact of physiotherapy access on health-related quality of life following hip fracture: an observational study on 30 752 hip fractures from the Norwegian Hip Fracture Register 2014–2018 

  Kjærvik, Cato; Gjertsen, Jan-Erik; Stensland, Eva; Taraldsen, Kristin; Uleberg, Bård Erling; Søreide, Odd (Journal article; Peer reviewed, 2024)

  Objectives The main objective of this study was to investigate the characteristics of patients receiving private community physiotherapy (PT) the first year after a hip fracture. Second, to determine whether utilisation ...

• Patient-reported outcome measures in hip fracture patients. Data on 35,206 patients from the Norwegian Hip Fracture Register, 2014 to 2018 

  Kjærvik, Cato; Gjertsen, Jan-Erik; Stensland, Eva; Dybvik, Eva Hansen; Søreide, Odd (Journal article; Peer reviewed, 2024)

  Aims The aims of this study were to assess quality of life after hip fractures, to characterize respondents to patient-reported outcome measures (PROMs), and to describe the recovery trajectory of hip fracture ...

• Antipsychotic use during pregnancy and risk of specific neurodevelopmental disorders and learning difficulties in children: a multinational cohort study 

  Bruno, Claudia; Cesta, Carolyn E.; Hjellvik, Vidar; Ulrichsen, Sinna Pilgaard; Bjørk, Marte-Helene; Esen, Buket Öztürk; Gillies, Malcolm B.; Gissler, Mika; Havard, Alys; Karlstad, Øystein; Leinonen, Maarit; Nørgaard, Mette; Pearson, Sallie-Anne; Reutfors, Johan; Furu, Kari; Cohen, Jacqueline Mallory; Zoega, Helga (Journal article; Peer reviewed, 2024)

  Background Antipsychotics are commonly prescribed to treat a range of psychiatric conditions in women of reproductive age and during pregnancy, including schizophrenia, bipolar disorder, anxiety, depression, autism ...

• BCG vaccination and multiple sclerosis risk: A Norwegian cohort study 

  Nakken, Ola; Aarseth, Jan Harald; Wergeland, Stig; Stigum, Hein; Meyer, Haakon Eduard; Holmøy, Trygve (Journal article; Peer reviewed, 2024)

  Introduction: Bacillus Calmette–Guérin (BCG) vaccination induces long-lasting effects on the adaptive and innate immune systems and prevents development of experimental autoimmune encephalomyelitis and possibly also ...

• Delirium is frequently underdiagnosed among older hospitalised patients despite available information in hospital medical records 

  Haugarvoll, Kristoffer; Solvang, Stein-Erik Hafstad; Norekvål, Tone Merete; Skogseth, Ragnhild Eide; andreassen, Ole A; Årsland, Dag; Neerland, Bjørn Erik; Nordrehaug, Jan Erik; Tell, Grethe S; Giil, Lasse Melvær (Journal article; Peer reviewed, 2024)

  Background In-hospital delirium is associated with adverse outcomes and is underdiagnosed, limiting research and clinical follow-up. Objective To compare the incidence of in-hospital delirium determined by chart-based ...

• Endometrial Pipelle Biopsy Computer-Aided Diagnosis: A Feasibility Study 

  Vermorgen, Sanne; Gelton, Thijs; Bult, Peter; Kusters-Vandevelde, Heidi V.N.; Hausnerová, Jitka; Van de Vijver, Koen; Davidson, Ben; Stefansson, Ingunn Marie; Kooreman, Loes F.S.; Qerimi, Adelina; Huvila, Jutta; Gilks, Blake; Shahi, Maryam; Zomer, Saskia; Bartosch, Carla; Pijnenborg, Johanna M.A.; Bulten, Johan; Ciompi, Francesco; Simons, Michiel (Journal article; Peer reviewed, 2023)

  Endometrial biopsies are important in the diagnostic workup of women who present with abnormal uterine bleeding or hereditary risk of endometrial cancer. In general, approximately 10% of all endometrial biopsies demonstrate ...

• The acute efect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults 

  Revheim, Ingrid; Ballance, Simon; Standal, Adelheid Fretland; Rieder, Anne; Dierkes, Jutta; Buyken, Anette E.; Gilja, Odd Helge; Rosendahl-Riise, Hanne (Journal article; Peer reviewed, 2024)

  Background The cereal fbre β-glucan reduces postprandial glycaemia, however, the underlying mechanisms are not fully understood. Thus, the aim of this study was to investigate the acute efect of a β-glucan-enriched oat ...

• Energy drink consumption and sleep parameters in college and university students: a national cross-sectional study 

  Kaldenbach, Siri; Hysing, Mari; Strand, Tor A.; Sivertsen, Børge (Journal article; Peer reviewed, 2024)

  Objectives: To investigate the frequency of energy drink (ED) consumption, and the association between ED consumption and selected sleep characteristics and parameters in Norwegian college and university students. We also ...

• Longitudinal Relationship Between Reduced Modic Change Edema and Disability and Pain in Patients With Chronic Low Back Pain 

  Espeland, Ansgar; Kristoffersen, Per Martin; Bråten, Lars Christian Haugli; Grøvle, Lars; Grotle, Margreth; Haugen, Anne Julsrud; Rolfsen, Mads Peder; Hellum, Christian; Zwart, John Anker Henrik; Storheim, Kjersti; Assmus, Jörg; Vetti, Nils (Journal article; Peer reviewed, 2023)

  Study Design. Secondary analyses of a randomized trial [Antibiotics In Modic changes (MCs) study]. Objective. To assess whether or not reduced MC edema over time is related to reduced disability and pain in patients ...

• Temporal trends in X-ray exposure during coronary angiography and percutaneous coronary intervention 

  Davidsen, Cedric; Bolstad, Kirsten Hansine Helene Nygaard; Nygaard, Ellisif; Vikenes, Kjell; Rotevatn, Svein; Tuseth, Vegard (Journal article; Peer reviewed, 2020)

  Background. Percutaneous coronary intervention exposes patient and staff to ionizing radiation. Although staff only receive a small fraction of patient dose through scatter radiation, there are concerns about the potential ...

• Neural tube defect among children in Addis Ababa Ethiopia: Epidemiological pattern and treatment outcome 

  Aklilu, Abenezer Tirsit (Doctoral thesis, 2024-08-23)

  Bakgrunn: Ni av ti barn med alvorlige medfødte misdannelser blir født i lav- og mellominntektsland (LMIC). Nevrale rørbrokk (NTD) er en av de vanligste misdannelsene. Målet med denne studien er å estimere forekomst, ...

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