• Hallmark Molecular and Pathological Features of POLG Disease are Recapitulated in Cerebral Organoids 

  Chen, Anbin; Yangzom, Tsering; Hong, Yu; Lundberg, Bjørn Christian; Sullivan, Gareth John; Tzoulis, Charalampos; Bindoff, Laurence Albert; Liang, Xiao (Journal article; Peer reviewed, 2024)

  In this research, a 3D brain organoid model is developed to study POLG-related encephalopathy, a mitochondrial disease stemming from POLG mutations. Induced pluripotent stem cells (iPSCs) derived from patients with these ...

• The prevalence of subdural blood products in extremely premature infants with no history of abusive head trauma, studied by magnetic resonance imaging around term-equivalent age 

  Fossmark, Maria Olsen; Bakøy, Hannah; Songstad, Nils Thomas; Köhler, Thorsten; Avenarius, Derk Frederik Matthaus; Aukland, Stein Magnus; Rosendahl, Karen (Journal article; Peer reviewed, 2024)

  Background Prematurity and enlarged subarachnoid spaces are both hypothesised to represent an increased risk of subdural haemorrhages (SDHs) in infancy, both with and without a history of abuse. Objective To examine ...

• Characteristics and demography of low energy fall injuries in patients > 60 years of age: a population-based analysis over a decade with focus on undertriage 

  Aarsland, Martine A.; Weber, Clemens; Enoksen, Cathrine Harstad; Dalen, Ingvild; Tjosevik, Kjell Egil; Oord, Pieter; Thorsen, Kenneth (Journal article; Peer reviewed, 2024)

  Background An increasing group of elderly patients is admitted after low energy falls. Several studies have shown that this patient group tends to be severely injured and is often undertriaged. Methods Patients > 60 ...

• The Therapeutic Potential of Exosomes from Mesenchymal Stem Cells in Multiple Sclerosis 

  Kråkenes, Torbjørn; Sandvik, Casper Eugen; Ytterdal, Marie; Gavasso, Sonia; Evjenth, Elisabeth Claire; Bø, Lars; Kvistad, Christopher Elnan (Journal article; Peer reviewed, 2024)

  Although treatment for multiple sclerosis (MS) has undergone a revolution in the last decades, at least two important barriers remain: alleviation of innate inflammation driving disease progression and promotion of ...

• Placental pathology and neonatal morbidity: exploring the impact of gestational age at birth 

  Budal, Elisabeth Berge; Kessler, Jørg; Eide, Geir Egil; Ebbing, Cathrine; Collett, Karin (Journal article; Peer reviewed, 2024)

  Aim To evaluate placental pathology in term and post-term births, investigate differences in clinical characteristics, and assess the risk of adverse neonatal outcome. Methods This prospective observational study ...

• A randomized trial on three different minimally invasive decompression techniques for lumbar spinal stenosis. Five years follow-up from the NORDSTEN-SST 

  Hermansen, Erland; Indrekvam, Kari; Franssen, Eric; Myklebust, Tor Åge; Austevoll, Ivar Magne; Hellum, Christian; Storheim, Kjersti; Bånerud, Ingrid Fjeldheim; Ebbs, Eira Kathleen; Aaen, Jørn Ståle; BANITALEBI, HASAN; Brox, Jens Ivar; Weber, Clemens; Solberg, Tore; Hjulstad, Arild; Brisby, Helena (Journal article; Peer reviewed, 2024)

  Purpose The short-term clinical outcome for midline-preserving posterior decompression techniques was comparable. The aim of this study was to evaluate long-term clinical results after three different midline-preserving ...

• Neurotrauma from fall accidents in Ethiopia 

  Teklemariam, Tsegazeab Laeke; Aklilu, Abenezer Tirsit; Moen, Bente Elisabeth; Lund-Johansen, Morten; Sundstrøm, Terje (Journal article; Peer reviewed, 2024)

  Background Ethiopia is a fast-growing economy with rapid urbanization and poor occupational safety measures. Fall injuries are common and frequently result in traumatic brain injury (TBI) or spinal cord injury (SCI). Methods We ...

• The association between lumbar lordosis preoperatively and changes in PROMs for lumbar spinal stenosis patients 2 years after spinal surgery: radiological and clinical results from the NORDSTEN-spinal stenosis trial 

  Wänman, Johan; Åkerstedt, Josefin; Banitalebi, Hasan; Myklebust, Tor Åge; Weber, Clemens; Storheim, Kjersti; Austevoll, Ivar Magne; Hellum, Christian; Indrekvam, Kari; Brisby, Helena; Hermansen, Erland (Journal article; Peer reviewed, 2024)

  Background Patients with lumbar spinal stenosis (LSS) sometimes have lower lumbar lordosis (LL), and the incidence of LSS correlates closely with the loss of LL. The few studies that have evaluated the association between ...

• Short and equal vascular stump length after standardized laparoscopic and open surgery with central lymphadenectomy for right-sided colon cancer 

  Lygre, Kristin Bentung; Eide, Geir Egil; Liedenbaum, Marjolein H.; Augland, Idun Magdalene; Haldorsen, Ingfrid S.; Pfeffer, Frank (Journal article; Peer reviewed, 2024)

• Do patients with lumbar spinal stenosis benefit from decompression of levels with adjacent moderate stenosis? A prospective cohort study from the NORDSTEN study 

  Tronstad, Sara; Haug, Knut Jørgen; Myklebust, Tor Åge; Weber, Clemens; Brisby, Helena; Austevoll, Ivar Magne; Hellum, Christian; Storheim, Kjersti; Aaen, Jørn Ståle; Banitalebi, Hasan; Brox, Jens Ivar; Grundnes, Oliver; Franssen, Eric; Indrekvam, Kari; Solberg, Tore; Hermansen, Erland (Journal article; Peer reviewed, 2024)

  Background Lumbar spinal stenosis (LSS) is characterized by pain that radiates to the buttocks and/or legs, aggravated by walking and relieved by forward flexion. There is poor correlation between clinical symptoms and ...

• Risk factors and evolution of weight loss in Parkinson's disease: A 9-year population-based study 

  Kristiansen, Ida; Hiorth, Ylva Hivand; Ushakova, Anastasia; Tysnes, Ole-Bjørn; Alves, Guido Werner (Journal article; Peer reviewed, 2024)

  Introduction: Weight loss is considered a common complication of Parkinson's disease (PD), but there are few prospective longitudinal studies on weight loss in patients followed from time of PD diagnosis. We sought to ...

• Refractory and super-refractory status epilepticus in children and adolescents: A population-based study 

  Hepsø, Seline Winsnes; Lee, Maya; Noszka, Kristoffer; Wollertsen, Yvonne; Holmaas, Gunhild; Kristensen, Erle; Eichele, Tom; Bjørk, Marte-Helene; Griffiths, Silja Torvik; Hikmat, Omar (Journal article; Peer reviewed, 2024)

  Purpose Refractory (RSE) and super-refractory status epilepticus (SRSE) are serious medical emergencies whose long-term outcomes depend on the timeliness of their management. Population-based clinical and epidemiological ...

• Host-gut microbiota interactions shape parasite infections in farmed Atlantic salmon 

  Brealey, Jaelle Caitlin; Kodama, Miyako; Agerbo Rasmussen, Jacob; Hansen, Søren B.; Santos-Bay, Luisa; Lecaudey, Laurene Alicia; Hansen, Martin; Fjære, Even; Myrmel, Lene Secher; Madsen, Lise; Bernhard, Annette; Sveier, Harald; Kristiansen, Karsten; Gilbert, M Thomas P; Martin, Michael David; Limborg, Morten Tønsberg (Journal article; Peer reviewed, 2024)

  Animals and their associated microbiota share long evolutionary histories. However, it is not always clear how host genotype and microbiota interact to affect phenotype. We applied a hologenomic approach to explore how ...

• Use of peripherally inserted central venous catheters and midline catheters for palliative care in patients with cancer: a systematic review 

  Gravdahl, Eva-Kristin Norum; Haugen, Dagny Renata Faksvåg; Fredheim, Olav Magnus Søndenå (Journal article; Peer reviewed, 2024)

  Background: Peripherally inserted central catheters (PICCs) and midline catheters (MCs) may offer convenient intravenous access, but evidence to support their place in palliative care is limited. This review aimed to assess ...

• The Prognostic Value of Human Papillomavirus Status in Penile Cancer: Outcomes From a Norwegian Cohort Study 

  Nordanger, Ida Marie; Beisland, Christian; Thorkelsen, Tor Kristian; Honore, Alfred; Juliebø-Jones, Patrick; Bostad, Leif Henry; Berget, Ellen; Costea, Daniela Elena; Moen, Christian Arvei (Journal article; Peer reviewed, 2024)

  Introduction: Penile squamous cell carcinoma (PSCC) can develop from human papillomavirus (HPV) infection. This study investigates if the prognostic value of the TNM stage groups or the components tumor stage (pT), grade ...

• Walking and balance in older adults with age-related hearing loss: A cross-sectional study of cases and matched controls 

  Kolasa, Sylwia Katarzyna; Magnussen, Liv Heide; Nilsen, Roy Miodini; Wilhelmsen, Kjersti Thulin; Goplen, Frederik Kragerud; Nordahl, Stein Helge Glad; Meldrum, Dara; Berge, Jan Erik; Hernes, Susanne M S; Steihaug, Ole Martin; Bogen, Bård Erik (Journal article; Peer reviewed, 2024)

  Background: Hearing loss (HL) is prevalent in older individuals. It is suggested that there is an association between age-related HL, walking and balance, leading to poorer function and increased risk of falls in older ...

• Brain Proteome Profiling Reveals Common and Divergent Signatures in Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy 

  Dick, Fiona; Johanson, Gard Aasmund Skulstad; Tysnes, Ole-Bjørn; Alves, Guido Werner; Dölle, Christian; Tzoulis, Charalampos (Journal article; Peer reviewed, 2024)

  The molecular pathogenesis of degenerative parkinsonisms, including Parkinson’s disease (PD), progressive supranuclear palsy (PSP), and Multiple system atrophy (MSA), remains largely unknown. To gain novel insight into ...

• Emerging Trends in AI and Radiomics for Bladder, Kidney, and Prostate Cancer: A Critical Review 

  Feretzakis, Georgios; Juliebø-Jones, Patrick; Tsaturyan, Arman; Sener, Tarik Emre; Verykios, Vassilios S.; Karapiperis, Dimitrios; Bellos, Themistoklis; Katsimperis, Stamatios; Angelopoulos, Panagiotis; Varkarakis, Ioannis; Skolarikos, Andreas; Somani, Bhaskar; Tzelves, Lazaros (Journal article; Peer reviewed, 2024)

  This comprehensive review critically examines the transformative impact of artificial intelligence (AI) and radiomics in the diagnosis, prognosis, and management of bladder, kidney, and prostate cancers. These cutting-edge ...

• Does the use of surgical face masks reduce postoperative infections in traumatic wounds sutured outside hospital? A randomized study at a Norwegian casualty center 

  Sælen, Kristoffer Holen; Hatlemark, Synne Josefin Myrvang; Brudvik, Christina Elisabeth; Bergh, Torbjørn Hiis; Bernardshaw, Soosaipillai V.; Steen, Knut (Journal article; Peer reviewed, 2024)

  Objective To investigate if wearing surgical face mask by doctors and nurses during suturing of traumatic wounds has any impact on postoperative infection rate. Design Randomized controlled study with masked or ...

• Unmasking Patient Diversity: Exploring Cognitive and Antidepressive Effects of Electroconvulsive Therapy 

  Sellevåg, Kjersti; Bartz-Johannessen, Christoffer; Ødegaard, Ketil Joachim; Nordenskjöld, Axel; Mohn, Hanne Christine; Bjørke, Jeanette Solheimslid; Kessler, Ute (Journal article; Peer reviewed, 2024)

  Background Electroconvulsive therapy (ECT) is an established treatment for depression, but more data on effectiveness and safety in clinical practice is needed. The aim of this register-based study was to investigate ...

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