• Plasma IL-1 and IL-6 Family Cytokines with Soluble Receptor Levels at Diagnosis in Head and Neck Squamous Cell Carcinoma: High Levels Predict Decreased Five-Year Disease-Specific and Overall Survival 

  Aarstad, Helene Hersvik; Moe, Svein Erik Emblem; Lybak, Stein; Bruserud, Øystein; Tvedt, Tor Henrik Anderson; Aarstad, Hans Jørgen (Journal article; Peer reviewed, 2024-04-12)

  Activation of the acute-phase cascade (APC) has been correlated with outcomes in various cancers, including head and neck squamous cell carcinoma (HNSCC). Primary drivers of the APC are the cytokines within the interleukin-6 ...

• Brystkreft hos menn – histopatologi og biomarkører 

  Lokøy, Ingvild Kathrin; Bakken, Inga Sofie; Wik, Elisabeth; Stefansson, Ingunn Marie (Journal article; Peer reviewed, 2024)

  Bakgrunn: Brystkreft hos menn utgjør om lag 1 % av alle tilfeller med brystkreft. Formålet med studien var å kartlegge histopatologiske parametere og utvalgte biomarkører hos menn med brystkreft. Materiale og metode: ...

• Effect of a vapor barrier in combination with active external rewarming for cold-stressed patients in a prehospital setting: a randomized, crossover field study 

  Mydske, Sigurd; Brattebø, Guttorm; Østerås, Øyvind; Wiggen, Øystein Nordrum; Assmus, Jörg; Thomassen, Øyvind (Journal article; Peer reviewed, 2024-04-25)

  Background: Use of a vapor barrier in the prehospital care of cold-stressed or hypothermic patients aims to reduce evaporative heat loss and accelerate rewarming. The application of a vapor barrier is recommended in various ...

• Glycemic response to meals with a high glycemic index differs between morning and evening: a randomized cross-over controlled trial among students with early or late chronotype 

  Stutz, Bianca; Krueger, Bettina; Goletzke, Janina; Jankovic, Nicole; Alexy, Ute; Herder, Christian; Dierkes, Jutta; Berg-Beckhoff, Gabriele; Jakobsmeyer, Rasmus; Reinsberger, Claus; Buyken, Anette E. (Journal article; Peer reviewed, 2024)

  Purpose: Glycemic response to the same meal depends on daytime and alignment of consumption with the inner clock, which has not been examined by individual chronotype yet. This study examined whether the 2-h postprandial ...

• Management of seizures in patients with primary mitochondrial diseases: consensus statement from the InterERNs Mitochondrial Working Group 

  Mancuso, Michelangelo; Papadopoulou, Maria T.; Ng, Yi Shiau; Ardissone, Anna; Bellusci, Marcello; Bertini, Enrico; Di Vito, Lidia; Evangelista, Teresinha; Fons, Carmen; Hikmat, Omar; Horvath, Rita; Klopstock, Thomas; Kornblum, Cornelia; Lamperti, Costanza; Licchetta, Laura; Molnar, Maria Judit; Varhaug, Kristin Nielsen; O'Callaghan, Mar; Pressler, Ronit M.; Schiff, Manuel; Servidei, Serenella; Szabo, Nora; Gorman, Gráinne S.; Cross, J Helen; Rahman, Shamima (Journal article; Peer reviewed, 2024)

  Background and purpose: Primary mitochondrial diseases (PMDs) are common inborn errors of energy metabolism, with an estimated prevalence of one in 4300. These disorders typically affect tissues with high energy requirements, ...

• Diagnosis and management in Rubinstein-Taybi syndrome: First international consensus statement 

  Lacombe, Didier; Bloch-Zupan, Agnès; Bredrup, Cecilie; Cooper, Edward B; Houge, Sofia Douzgou; García-Miñaúr, Sixto; Kayserili, Hülya; Larizza, Lidia; Lopez Gonzalez, Vanesa; Menke, Leonie A; Milani, Donatella; Saettini, Francesco; Stevens, Cathy A; Tooke, Lloyd; Van der Zee, Jill A; Genderen, Maria M Van; Van-Gils, Julien; Waite, Jane; Adrien, Jean-Louis; Bartsch, Oliver; Bitoun, Pierre; Bouts, Antonia H M; Cueto-González, Anna M; Dominguez-Garrido, Elena; Duijkers, Floor A; Fergelot, Patricia; Halstead, Elisabeth; Huisman, Sylvia A; Meossi, Camilla; Mullins, Jo; Nikkel, Sarah M; Oliver, Chris; Prada, Elisabetta; Rei, Alessandra; Riddle, Ilka; Rodriguez-Fonseca, Cristina; Pena, Rebecca Rodríguez; Russell, Janet; Saba, Alicia; Santos-Simarro, Fernando; Simpson, Brittany N; Smith, David F; Stevens, Markus F; Szakszon, Katalin; Taupiac, Emmanuelle; Totaro, Nadia; Palafoll, Irene Valenzuena; Van Der Kaay, Daniëlle C M; Van Wijk, Michiel P; Vyshka, Klea; Wiley, Susan; Hennekam, Raoul C (Journal article; Peer reviewed, 2024)

  Rubinstein-Taybi syndrome (RTS) is an archetypical genetic syndrome that is characterised by intellectual disability, well-defined facial features, distal limb anomalies and atypical growth, among numerous other signs and ...

• Safety and tolerability of β-blockers: importance of cardioselectivity 

  Marti, Hans Peter; Pavía López, Abel Alberto; Schwartzmann, Pedro (Journal article; Peer reviewed, 2024)

  Cardioselective β-blockade is generally well tolerated in practice and contraindications to this therapy are uncommon. β-blockers are a diverse therapeutic class, and their individual tolerability profiles are influenced ...

• What predicts citation counts and translational impact in headache research? A machine learning analysis 

  Danelakis, Antonios; Langseth, Helge; Nachev, Parashkev; Nelson, Amy; Bjørk, Marte-Helene; Matharu, Manjit Singh; Tronvik, Erling Andreas; May, Arne; Stubberud, Anker (Journal article; Peer reviewed, 2024)

  Background: We aimed to develop the first machine learning models to predict citation counts and the translational impact, defined as inclusion in guidelines or policy documents, of headache research, and assess which ...

• Psychometric Properties and Concurrent Validity of a 10-Item Questionnaire for Patients With Vestibular Disorders 

  Knapstad, Mari Kalland; Heggdal, Peder Olaf Laugen; Berge, Jan Erik; Nordahl, Stein Helge Glad; Goplen, Frederik Kragerud (Journal article; Peer reviewed, 2024)

  Objective: This study aimed to investigate the psychometric properties and concurrent validity of the Haukeland Dizziness Questionnaire (HDQ-10), a 10-item questionnaire designed for simplified assessment of symptom severity ...

• Risk of Major Congenital Malformations and Exposure to Antiseizure Medication Monotherapy 

  Battino, Dina; Tomson, Torbjörn; Bonizzoni, Erminio; Craig, John; Perucca, Emilio; Sabers, Anne; Thomas, Sanjeev; Alvestad, Silje; Perucca, Piero; Vajda, Frank (Journal article; Peer reviewed, 2024)

  Importance: Women with epilepsy (WWE) require treatment with antiseizure medications (ASMs) during pregnancy, which may be associated with an increased risk of major congenital malformations (MCMs) in their offspring. ...

• Tear cytokine levels are reduced in patients treated with intravitreal injections 

  Malmin, Agni; Thomseth, Vilde Marie; Førland, Per Tore; Aass, Hans Christian; Reppe, Sjur; Olsen, Markus Vicente Tørud; Lindtjørn, Birger; Chen, Xiangjun; Haugen, Inga Britt Kjellevold; Utheim, Tor Paaske; Forsaa, Vegard Asgeir (Journal article; Peer reviewed, 2024)

  Purpose: To investigate cytokine levels in the tear fluid of patients receiving serial intravitreal injections (IVI) with anti-vascular endothelial growth factor (anti-VEGF) for neovascular age-related macular degeneration ...

• Cross-sectional analysis of use of real-world data in single technology appraisals of oncological medicine by the National Institute for Health and Care Excellence in 2011-2021 

  Kang, Jiyeon; Cairns, John Alexander (Journal article; Peer reviewed, 2024)

  Objectives This study aims to identify how real-world data (RWD) have been used in single technology appraisals (STAs) of cancer drugs by the National Institute for Health and Care Excellence (NICE). Design Cross-sectional ...

• Transient Neonatal Myasthenia Gravis as a Common Complication of a Rare Disease: A Systematic Review 

  Lindroos, Jenny Linnea Victoria; Bjørk, Marte-Helene; Gilhus, Nils Erik (Journal article; Peer reviewed, 2024)

  Myasthenia gravis (MG) is a rare autoimmune disease. Transient neonatal myasthenia gravis (TNMG) is caused by pathogenic maternal autoantibodies that cross the placenta and disrupt signaling at the neuromuscular junction. ...

• Malnutrition as a prognostic factor for 2-year mortality in hospitalized patients in Norway: A matched cohort study 

  Trollebø, Marte Almenning; Tangvik, Randi Julie; Skeie, Eli; Grønning, Martin Kristoffer; Nygård, Ottar Kjell; Eagan, Tomas Mikal Lind; Dierkes, Jutta (Journal article; Peer reviewed, 2024)

  Background: Risk of malnutrition and malnutrition have been previously associated with increased risk of mortality. It remains unclear, however, whether the severity of malnutrition differentiates in association with ...

• ESR essentials: MRI of the knee—practice recommendations by ESSR 

  Parkar, Anagha P; Adriaensen, Miraude E. A. P. M. (Journal article; Peer reviewed, 2024)

  Many studies and systematic reviews have been published about MRI of the knee and its structures, discussing detailed anatomy, imaging findings, and correlations between imaging and clinical findings. This paper includes ...

• Biological implications of the hypervariable VNTR region in the carboxyl ester lipase (CEL) gene 

  Brekke, Ranveig Seim (Doctoral thesis, 2025-05-07)

  Karboksylester-lipase (CEL) er eit fordøyingsenzym som hovudsakleg blir uttrykt i bukspyttkjertelen. CEL-genet inneheld ein region med repeterte DNA-sekvensar i det siste eksonet, også kalla ein VNTR-region. Repetisjonslengder ...

• Classification of Vitamin D Status Based on Vitamin D Metabolism: A Randomized Controlled Trial in Hypertensive Patients 

  Zelzer, Sieglinde; Meinitzer, Andreas; Enko, Dietmar; Keppel, Martin H.; Herrmann, Markus; Theiler-Schwetz, Verena; Trummer, Christian; Schmitt, Lisa; Tomaschitz, Andreas; Sadoghi, Patrick; Dierkes, Jutta; Pludowski, Pawel; Zittermann, Armin; März, Winfried; Pilz, Stefan (Journal article; Peer reviewed, 2024)

  Circulating 25-hydroxyvitamin D (25(OH)D) is the generally accepted indicator of vitamin D status. Since hydroxylation of 25(OH)D to 24-25-dihydroxyvitamin D (24,25(OH)2D) is the first step of its catabolism, it has been ...

• The Dark and Gloomy Brain: Grey Matter Volume Alterations in Major Depressive Disorder-Fine-Grained Meta-Analyses 

  Romeo, Zaira; Biondi, Margherita; Oltedal, Leif; Spironelli, Chiara (Journal article; Peer reviewed, 2024)

  Background: While the brain correlates of major depressive disorder (MDD) have been extensively studied, there is no consensus conclusion so far. Various meta-analyses tried to determine the most consistent findings, but ...

• Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas 

  Brekke, Ranveig Seim; Svanbring, Anny Gravdal; Jellas, Khadija el; Curry, Grace E; Lin, Jianguo; Wilhelm, Steven J; Steine, Solrun; Mas, Eric; Johansson, Stefan; Lowe, Mark E; Johansson, Bente Berg; Xiao, Xunjun; Fjeld, Karianne; Molven, Anders (Journal article; Peer reviewed, 2024)

  The CEL gene encodes carboxyl ester lipase, a pancreatic digestive enzyme. CEL is extremely polymorphic due to a variable number tandem repeat (VNTR) located in the last exon. Single-base deletions within this VNTR cause ...

• Factors Underlying the Difference in Response to Fecal Microbiota Transplantation Between IBS Patients with Severe and Moderate Symptoms 

  El-Salhy, Magdhy; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2024)

  Background: Previous studies showed that patients with Severe IBS respond better to fecal microbiota transplantation (FMT) than do those with Moderate IBS. Aims: The present study aimed to determine the effects of the ...

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