Department of Clinical Medicine
Recent Submissions
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The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial
(Journal article; Peer reviewed, 2020)Purpose: Although corticosteroids are frequently used in patients with advanced cancer, few studies have examined the impact of these drugs on patient-reported sleep. We aimed to examine the short-term impact of ... -
Intrauterine growth restriction, preterm birth and risk of end-stage renal disease during the first 50 years of life
(Journal article; Peer reviewed, 2020)Background: Low birth weight (LBW) is associated with a higher risk of end-stage renal disease (ESRD). The relative impacts of absolute birth weight, birth weight in relation to gestational age and preterm birth are, ... -
Hip fracture treatment in Norway - deviation from evidence-based treatment guidelines: data from the Norwegian Hip Fracture Register, 2014 to 2018
(Others, 2020)Aims The aim of this study was to describe variation in hip fracture treatment in Norway expressed as adherence to international and national evidence-based treatment guidelines, to study factors influencing deviation ... -
Global FKRP Registry: observations in more than 300 patients with Limb Girdle Muscular Dystrophy R9
(Journal article; Peer reviewed, 2020-04)Objective The Global FKRP Registry is a database for individuals with conditions caused by mutations in the Fukutin‐Related Protein (FKRP) gene: limb girdle muscular dystrophy R9 (LGMDR9, formerly LGMD2I) and congenital ... -
Exploring the genetic contribution to idiopathic Parkinson disease
(Doctoral thesis, 2021-03-05)Background: Parkinson disease (PD) is a major cause of death and disability and has a devastating global socioeconomic impact. It affects 1-2% of the population above the age of 65 and its prevalence increases as the ... -
Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci
(Journal article; Peer reviewed, 2020-10-01)Parkinson disease (PD) is a complex neurodegenerative disorder influenced by both environmental and genetic factors. While genome wide association studies have identified several susceptibility loci, many causal variants ... -
The power of empirical data; lessons from the clinical registry initiatives in Scandinavian cancer care
(Journal article; Peer reviewed, 2020)Background In Scandinavia, there is a strong tradition for research and quality monitoring based on registry data. In Denmark, Norway and Sweden, 63 clinical registries collect data on disease characteristics, treatment ... -
Comparable Increases in Dural Sac Area After Three Different Posterior Decompression Techniques for Lumbar Spinal Stenosis: Radiological Results From a Randomized Controlled Trial in the NORDSTEN Study
(Journal article; Peer reviewed, 2020)Purpose: To investigate changes in dural sac area after three different posterior decompression techniques in patients undergoing surgery for lumbar spinal stenosis. Decompression of the nerve roots is the main surgical ... -
Effects of using the MyFood decision support system on hospitalized patients' nutritional status and treatment: A randomized controlled trial
(Journal article; Peer reviewed, 2020)Background & aims Compliance to guidelines for disease-related malnutrition is documented as poor. The practice of using paper-based dietary recording forms with manual calculation of the patient's nutritional intake is ... -
Cemented or uncemented hemiarthroplasty for femoral neck fracture? Data from the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2020)Background A displaced femoral neck fracture in patients older than 70 years is a serious injury that influences the patient’s quality of life and can cause serious complications or death. Previous national guidelines ... -
Compliance with national guidelines for antibiotic prophylaxis in hip fracture patients: A quality assessment study of 13 329 patients in the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2020)Objective We assessed compliance with new guidelines for prophylactic antibiotics in hip fracture surgery in Norway introduced in 2013. Design The data from the Norwegian Hip Fracture Register was used to assess the ... -
Non-metastatic prostate cancer: rationale for conservative treatment and impact on disease-related morbidity and mortality in the elderly
(Journal article; Peer reviewed, 2020)Purpose: To determine the rationale for not offering local treatment to prostate cancer patients with non-metastatic disease at diagnosis who later died of prostate cancer and to document local and systemic complications ... -
Effects of Plant-Based Diets on Outcomes Related to Glucose Metabolism: A Systematic Review
(Journal article; Peer reviewed, 2020)According to the rising prevalence of obesity and metabolic disorders leading to impaired glucose metabolism, effective strategies to prevent and/or delay the onset of disease are of great need. A plant-based diet has been ... -
Weight changes and mobility in the early phase after hip fracture in community-dwelling older persons
(Journal article; Peer reviewed, 2020)Purpose Hip fractures in older persons are associated with reduced mobility and loss of independence. Few studies address the nutritional status and mobility in the early phase after hip fracture. The objective of the ... -
A Patient With Maculopapular Rash and Lichenoid Skin Damage Caused by Ponatinib
(Journal article; Peer reviewed, 2020)Tyrosine kinase inhibitors (TKIs) are invaluable for the treatment of patients with chronic myelogenous leukemia. Although TKIs are generally better tolerated than traditional chemotherapy, dermatologic side effects are ... -
Anaphylaxis following prick-by-prick testing with peanut
(Journal article; Peer reviewed, 2020)Anaphylaxis due to prick‐by‐prick testing is a rare but potentially life‐threatening complication. Personnel performing testing should be able to recognize and treat anaphylaxis. Adrenaline must be available. In high‐risk ... -
Health promotion intervention for people with early-stage dementia: A quasi-experimental study
(Journal article; Peer reviewed, 2020)Introduction: With the limited advancements in medical treatment, there is a growing need for supporting people with early‐stage dementia adjust to their diagnosis and improve their quality of life. This study aimed to ... -
Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services
(Journal article; Peer reviewed, 2020)Background The ongoing pandemic is having a collateral health effect on delivery of surgical care to millions of patients. Very little is known about pandemic management and effects on other services, including delivery ... -
Effects of high intake of cod or salmon on gut microbiota profile, faecal output and serum concentrations of lipids and bile acids in overweight adults: a randomised clinical trial
(Journal article; Peer reviewed, 2020-10-27)Purpose To explore whether high intake of cod or salmon would affect gut microbiota profile, faecal output and serum concentrations of lipids and bile acids. Methods Seventy-six adults with overweight/obesity with no ... -
Cognitive impairment influences the risk of reoperation after hip fracture surgery: results of 87,573 operations reported to the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2020)Background and purpose — About one-fourth of hip fracture patients have cognitive impairment. We investigated whether patients’ cognitive function affects surgical treatment, risk of reoperation, and mortality after hip ...
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