• The epithelial–mesenchymal transition regulators Twist, Slug, and Snail are associated with aggressive tumour features and poor outcome in prostate cancer patients 

  Børretzen, Astrid; Gravdal, Karsten; Haukaas, Svein Andreas; Mannelqvist, Monica; Beisland, Christian; Akslen, Lars Andreas; Halvorsen, Ole Johan (Journal article; Peer reviewed, 2021)

  The prognostic importance of transcription factors promoting epithelial–mesenchymal transition (EMT) and angiogenesis has not been well explored in prostate cancer patients with long follow-up, nor the interplay between ...

• Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer 

  Ytre-Hauge, Sigmund; Salvesen, Øyvind; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021-01)

  BACKGROUND To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ...

• Sex-specific outcome disparities in very old patients admitted to intensive care medicine: a propensity matched analysis 

  Wernly, Bernhard; Bruno, Raphael Romano; Kelm, Malte; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn Husøy; Artigas, Antonio; Finazzi, Stefano; Cecconi, Maurizio; Christensen, Steffen; Faraldi, Loredana; Lichtenauer, Michael; Muessig, Johanna M.; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Öhman, Christina Agwald; Pinto, Bernadro Bollen; Soliman, Ivo W.; Szczeklik, Wojciech; Niederseer, David; Valentin, Andreas; Watson, Ximena; Leaver, Susannah; Boulanger, Carole; Walther, Sten; Schefold, Jörg C.; Joannidis, Michael; Nalapko, Yuriy; Elhadi, Muhammed; Fjølner, Jesper; Zafeiridis, Tilemachos; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans; Jung, Christian (Journal article; Peer reviewed, 2020)

  Female and male very elderly intensive patients (VIPs) might differ in characteristics and outcomes. We aimed to compare female versus male VIPs in a large, multinational collective of VIPs with regards to outcome and ...

• What Do We Mean by "Stone Free," and How Accurate Are Urologists in Predicting Stone-Free Status Following Ureteroscopy? 

  Ulvik, Øyvind; Harneshaug, Jill-Randi; Gjengstø, Peder (Journal article; Peer reviewed, 2021)

  Background and Purpose: No consensus exists on how stone-free rates (SFRs) should be reported after stone treatment. The aim of this study was to assess how accurate urologists predict their patients being stone free after ...

• Ureteral Strictures Following Ureteroscopic Stone Treatment 

  Ulvik, Øyvind; Harneshaug, Jill-Randi; Gjengstø, Peder (Journal article; Peer reviewed, 2020)

  Background and Purpose: Ureteral stricture is a rare, but serious complication following ureteroscopy (URS) for stones. The aim of this study was to investigate how many patients ended up with a ureteral stricture after ...

• Post hepatectomy liver failure (PHLF) – Recent advances in prevention and clinical management 

  Søreide, Jon Arne; Deshpande, Rahul (Journal article; Peer reviewed, 2021)

  Background Posthepatectomy liver failure (PHLF) is a relatively rare but feared complication following liver surgery, and associated with high morbidity, mortality and cost implications. Significant advances have been ...

• Oedema on STIR modified the effect of amoxicillin as treatment for chronic low back pain with Modic changes—subgroup analysis of a randomized trial 

  Kristoffersen, Per M; Bråten, Lars Christian Haugli; Vetti, Nils; Grøvle, Lars; Hellum, Christian; Storheim, Kjersti; Zwart, John-Anker; Assmus, Jörg; Espeland, Ansgar (Journal article; Peer reviewed, 2021)

  Objective To evaluate potential MRI-defined effect modifiers of amoxicillin treatment in patients with chronic low back pain and type 1 or 2 Modic changes (MCs) at the level of a previous lumbar disc herniation (index ...

• Wearing-off at the end of natalizumab dosing interval and risk of MS disease activity: A prospective 1-year follow-up study 

  Bringeland, Gerd Haga; Myhr, Kjell-Morten; Vedeler, Christian A.; Gavasso, Sonia (Journal article; Peer reviewed, 2020)

  Natalizumab effectively prevents disease activity in relapsing-remitting multiple sclerosis by binding α4 integrin and inhibiting leukocyte migration to the central nervous system. We recently reported an association between ...

• Strategies for the delay of surgery in the management of resectable hepatobiliary malignancies during the COVID-19 pandemic 

  Bennett, Sean; Søreide, Kjetil; Gholami, Sepideh; Pessaux, Patrick; Teh, Catherine S.C.; Segelov, Eva; Kennecke, Hagen Fritz; Prenen, Hans; Myrehaug, Sten D.; Callegaro, Dario; Hallet, Julie (Journal article; Peer reviewed, 2020)

  Objective: We aimed to review data about delaying strategies for the management of hepatobiliary cancers requiring surgery during the covid-19 pandemic. Background: Given the covid-19 pandemic, many jurisdictions, to spare ...

• The impact of lifestyle factors on disease risk and long-term disability progression in multiple sclerosis 

  Wesnes, Kristin (Doctoral thesis, 2021-06-04)

  Background: Multiple sclerosis (MS) is a disabling inflammatory disease of the central nervous system (CNS) likely caused by genetic susceptible variants and environmental triggers. Low vitamin D levels and smoking are ...

• Sex-specific outcome disparities in very old patients admitted to intensive care medicine: a propensity matched analysis 

  Wernly, Bernhard; Bruno, Raphael Romano; Kelm, Malte; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn Husøy; Artigas, Antonio; Finazzi, Stefano; Cecconi, Maurizio; Christensen, Steffen; Faraldi, Loredana; Lichtenauer, Michael; Muessig, Johanna M.; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Öhman, Christina Agwald; Pinto, Bernadro Bollen; Soliman, Ivo W.; Szczeklik, Wojciech; Niederseer, David; Valentin, Andreas; Watson, Ximena; Leaver, Susannah; Boulanger, Carole; Walther, Sten; Schefold, Jörg C.; Joannidis, Michael; Nalapko, Yuriy; Elhadi, Muhammed; Fjølner, Jesper; Zafeiridis, Tilemachos; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans; Jung, Christian (Journal article; Peer reviewed, 2020)

  Female and male very elderly intensive patients (VIPs) might differ in characteristics and outcomes. We aimed to compare female versus male VIPs in a large, multinational collective of VIPs with regards to outcome and ...

• Personalized estimation of one-year mortality risk after elective hip or knee arthroplasty for osteoarthritis. 

  Trela-Larsen, L; Kroken, Gard; Bartz-Johannessen, Christoffer; Sayers, Adele; Aram, P; McCloskey, Eugene; Kadirkamanathan, V; Blom, A; Lie, Stein Atle; Furnes, Ove; Wilkinson, J. Mark (Journal article; Peer reviewed, 2020)

  Aims To develop and validate patient-centred algorithms that estimate individual risk of death over the first year after elective joint arthroplasty surgery for osteoarthritis. Methods A total of 763,213 hip and knee ...

• Low vitamin D, but not tobacco use or high BMI, is associated with long-term disability progression in multiple sclerosis 

  Wesnes, Kristin; Myhr, Kjell-Morten; Riise, Trond; Stokke, Silje Agnethe; Torkildsen, Øivind; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Bjørnevik, Kjetil Lauvland (Journal article; Peer reviewed, 2021)

  Background: Low vitamin D levels, tobacco use and high body mass index (BMI) have been linked to adverse disease outcomes in multiple sclerosis (MS), but their influence on long-term disability progression remains unclear. ...

• Data entry quality of double data entry vs automated form processing technologies: A cohort study validation of optical mark recognition and intelligent character recognition in a clinical setting 

  Paulsen, Aksel; Harboe, Knut; Dalen, Ingvild (Journal article; Peer reviewed, 2020)

  Background and Aims Patient-reported outcome measures (PROMs) are increasingly used in health services. Paper forms are still often used to register such data. Manual double data entry (DDE) has been defined as the gold ...

• Decreased survival of medial pivot designs compared with cruciate-retaining designs in TKA without patellar resurfacing. 

  Øhrn, Frank-David; Gøthesen, Øystein; Lygre, Stein Håkon Låstad; Peng, Yi; Lian, Øystein Bjerkestrand; Lewis, Peter L; Furnes, Ove; Röhrl, Stephan Maximillian (Journal article; Peer reviewed, 2020)

  Background The medial pivot TKA design was introduced in the 1990s. These are fixed-bearing, medial-conforming implants with virtually no translation in the medial part of the knee, in contrast to the flat lateral part ...

• Reduced grey- and white matter volumes due to unilateral hearing loss following treatment for vestibular schwannoma 

  Heggdal, Peder Olaf Laugen; Larsen, Kristina S.; Brännström, Jonas; Aarstad, Hans Jørgen; Specht, Karsten (Journal article; Peer reviewed, 2020)

  Objective Previous studies of the consequences of unilateral hearing loss (UHL) on the functional-structural organization of the brain has included subjects with various degrees of UHL. We suggest that the consequences ...

• Hyperferritinemi-katarakt-syndrom 

  Benneche, Andreas; Sandnes, Miriam; Bakke, Åsne; Reikvam, Håkon (Journal article; Peer reviewed, 2020)

• COVID-19 and venous thromboembolism - prophylaxis and treatment 

  Kvåle, Reidar; Azrakhsh, , Nessar Ahmad; Mohn, Kristin Greve Isdahl; Aanerud, Marianne; Guttormsen, Anne Berit; Reikvam, Håkon (Journal article; Peer reviewed, 2020)

• Plasma levels of guanylins are reduced in patients with Crohn’s disease 

  Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Tronstad, Rune Rose; Dizdar, Vernesa; Nylund, Kim; Hanevik, Kurt; Hausken, Trygve; Gilja, Odd Helge; Fiskerstrand, Torunn (Journal article; Peer reviewed, 2020)

  Background: Guanylin (GN) and uroguanylin (UGN) are endogenous ligands for the intestinal receptor guanylate cyclase C (GC-C), an important regulator of intestinal fluid homeostasis. Gene expression and protein levels of ...

• Disc and nerve root findings on lumbar MRI with straightened vs flexed hips and knees—pilot study 

  Espeland, Ansgar; Seime, Nina Dalen (Journal article, 2019)

  Objective: To compare disc and nerve root findings, image quality, and pain between supine lumbar MRI positions with straightened vs flexed hips and knees. Methods: In this prospective pilot study, 14 adults with sciatica ...

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