Department of Clinical Medicine
Recent Submissions
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The unmet need for treatment of children with musculoskeletal impairment in Malawi
(Journal article; Peer reviewed, 2022)Background More than a billion people globally are living with disability and the prevalence is likely to increase rapidly in the coming years in low- and middle-income countries (LMICs). The vast majority of those living ... -
An exploration of the sustainability of dinner recipes
(Master thesis, 2022-05-13) -
A nationwide study of the incidence, prevalence and mortality of Parkinson’s disease in the Norwegian population
(Journal article; Peer reviewed, 2022)Epidemiological studies of Parkinson’s disease (PD) show variable and partially conflicting findings with regard to incidence, prevalence, and mortality. These differences are commonly attributed to technical and methodological ... -
Ankle fractures: a systematic review of patient‑reported outcome measures and their measurement properties
(Journal article; Peer reviewed, 2022)Purpose Ankle fractures are commonly occurring fractures, especially in the aging population, where they often present as fragility fractures. The disease burden and economic costs to the patient and society are considerable. ... -
Paraneoplastic and Other Autoimmune Encephalitides: Antineuronal Antibodies, T Lymphocytes, and Questions of Pathogenesis
(Journal article; Peer reviewed, 2022)Autoimmune and paraneoplastic encephalitides represent an increasingly recognized cause of devastating human illness as well as an emerging area of neurological injury associated with immune checkpoint inhibitors. Two ... -
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson’s disease
(Journal article; Peer reviewed, 2022)We conducted a double-blinded phase I clinical trial to establish whether nicotinamide adenine dinucleotide (NAD) replenishment therapy, via oral intake of nicotinamide riboside (NR), is safe, augments cerebral NAD levels, ... -
Interobserver agreement and prognostic impact for MRI–based 2018 FIGO staging parameters in uterine cervical cancer
(Journal article; Peer reviewed, 2022)Objectives To evaluate the interobserver agreement for MRI–based 2018 International Federation of Gynecology and Obstetrics (FIGO) staging parameters in patients with cervical cancer and assess the prognostic value of ... -
MRI-assessed tumor-free distance to serosa predicts deep myometrial invasion and poor outcome in endometrial cancer
(Journal article; Peer reviewed, 2022)Objectives To explore the diagnostic accuracy of preoperative magnetic resonance imaging (MRI)-derived tumor measurements for the prediction of histopathological deep (≥ 50%) myometrial invasion (pDMI) and prognostication ... -
POLG mutations lead to abnormal mitochondrial remodeling during neural differentiation of human pluripotent stem cells via SIRT3/AMPK pathway inhibition
(Journal article; Peer reviewed, 2022)We showed previously that POLG mutations cause major changes in mitochondrial function, including loss of mitochondrial respiratory chain (MRC) complex I, mitochondrial DNA (mtDNA) depletion and an abnormal NAD+/NADH ratio ... -
Health-related quality of life in older patients surviving ICU treatment for COVID-19: results from an international observational study of patients older than 70 years
(Journal article; Peer reviewed, 2022)Background health-related quality of life (HRQoL) is an important patient-centred outcome in patients surviving ICU admission for COVID-19. It is currently not clear which domains of the HRQoL are most affected. Objective to ... -
Prevalence of self-reported emotional, physical, and sexual abuse and association with fear of childbirth in pregnant women with epilepsy: The Norwegian Mother, Father, and Child Cohort Study
(Journal article; Peer reviewed, 2022)Objective This study was undertaken to examine the prevalence of self-reported experiences with abuse in pregnant women with epilepsy and the association between having experienced abuse and childbirth expectations, ... -
Stable isotope ratios of carbon and nitrogen after weight loss A secondary analysis of the CarbFunc study
(Master thesis, 2022-05-18)Bakgrunn: Det økende helseproblemet med overvekt og fedme har ført til et fornyet fokus på vekttap, samtidig som utilsiktet vekttap knyttet til enten alder eller sykdom har blitt et klinisk problem. Vekttap kan være ... -
Malnutrition in cancer patients receiving palliative care
(Master thesis, 2022-05-13) -
The relationship between relevant biomarkers and perceived hunger during the postprandial period in healthy young adults: The PoMet intervention study
(Master thesis, 2022-05-13)Abstract Background: A lot of research has been conducted on the field of appetite regulation. However, less in known about the impact of the metabolic switch and the increasing ketone production on subjective feelings of ... -
Association between C-reactive protein levels and antipsychotic treatment during 12 months follow-up period after acute psychosis
(Journal article; Peer reviewed, 2022)Background A potential role of inflammatory pathways in the pathology of schizophrenia has been suggested for at least a subgroup of patients. Elevated levels of the inflammatory marker C-reactive protein (CRP) have been ... -
Reliability of preoperative MRI findings in patients with lumbar spinal stenosis
(Journal article; Peer reviewed, 2022)Background Magnetic Resonance Imaging (MRI) is an important tool in preoperative evaluation of patients with lumbar spinal stenosis (LSS). Reported reliability of various MRI findings in LSS varies from fair to excellent. ... -
Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures
(Journal article; Peer reviewed, 2022)High frequency of convulsive seizures and long-lasting epilepsy are associated with an increased risk of sudden unexpected death in epilepsy (SUDEP). Structural changes in the myocardium have been described in SUDEP victims. ... -
Postprandial metabolism in healthy young subjects (PoMet)
(Master thesis, 2022-05-13)Introduction: When measuring nutritional biomarkers in blood, recent food intake can greatly impact the concentrations. Hence, it may be important to consider prandial status when interpreting the biomarker concentrations. ... -
Emerging Role of Epigenetic Alterations as Biomarkers and Novel Targets for Treatments in Pancreatic Ductal Adenocarcinoma
(Journal article; Peer reviewed, 2022)Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment options. Emerging evidence shows that epigenetic alterations are present in PDAC. The changes are potentially reversible and therefore ... -
Subsequent ipsi- and contralateral femoral fractures after intramedullary nailing of a trochanteric or subtrochanteric fracture: a cohort study on 2012 patients
(Journal article; Peer reviewed, 2022-04-28)Background: The literature is inconclusive as to whether an intramedullary nail changes the distribution of a subsequent ipsi- or contralateral fracture of the femur. We have compared the incidence, localisation, and ...