Department of Clinical Medicine
Recent Submissions
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The relevance of bread consumption for body weight and glycaemic control : Epidemiological and clinical studies in humans
(Doctoral thesis, 2024-12-16)Bakgrunn: Brød er en høyt konsumert matvare som, avhengig av brødtype og næringsinnhold, kan utgjøre en av våre viktigste kilder til fullkorn og kostfiber – næringsstoffer som er assosiert med en rekke gunstige helseeffekter ... -
Evaluation of Patellar Dysplasia and Postoperative Pain After Mini-Open, Thin-Flap Trochleoplasty: A Retrospective Analysis of 75 Consecutive Cases
(Journal article; Peer reviewed, 2024)Background: The association between inherent patellar anatomy and postoperative pain after trochleoplasty in patients with patellar instability is poorly understood. Purpose/Hypothesis: The study purpose was to evaluate ... -
Electroconvulsive Therapy (ECT) in Depression : Clinical Use and Acute and Long-term Effect and Side-Effects
(Doctoral thesis, 2024-12-10)Introduksjon: Elektrokonvulsiv terapi (ECT) har effekt i unipolar- og bipolar depresjon, men meir informasjon frå pasient-perspektivet og om langtids effekter og kognitive biverknader vil betre samtykkeprossessen. Mål: ... -
MRI of Modic changes in chronic low back pain : Reliability and relation to effect of antibiotic treatment
(Doctoral thesis, 2024-12-06)Sammendrag Bakgrunn Modicforandringer (MCs) i virvelkroppene i ryggen identifiseres på T1- og T2-vektet magnetisk resonanstomografi (MR) serier, der Modic-forandringer type 1 (MC1) karakteriseres ved ødemsignaler og type ... -
Paraneoplastic cerebellar degeneration: Exploring the roles of the cerebellar degeneration-related proteins and exosomal microRNAs
(Doctoral thesis, 2024-12-10)Bakgrunn: Paraneoplastisk cerebellær degenerasjon (PCD) er eit av dei vanlegaste paraneoplastiske nevrologiske syndroma - ei gruppe sjeldne, immunmedierte syndrom assosiert med kreft. Individ med PCD har autoantistoff i ... -
Struggling with Fitting in: Clients Mixed Experiences of Receiving Job Support and Getting a Job When Participating in Individual Placement and Support in Norway
(Journal article; Peer reviewed, 2024)Purpose: To explore clients’ experiences of receiving job support from employment specialists (ESs) working with individual placement and support (IPS) in Norway. IPS is developed to help people with severe mental illness ... -
Effects of Dietary Intake of Marine Ingredients on the Circulating Total Cholesterol Concentration in Domestic Dogs: A Systematic Review and Meta-Analysis
(Journal article; Peer reviewed, 2024)A high circulating total cholesterol (TC) concentration increases the risk for atherosclerosis in the domestic dog. Intake of marine foods is associated with a lowering effect on circulating TC concentration in humans and ... -
Age-Related Clusters and Favorable Immune Phenotypes in Breast Cancer of the Young Patients
(Journal article; Peer reviewed, 2024)Breast cancer (BC) patients aged <40 years at diagnosis experience aggressive disease and poorer survival compared with women diagnosed with BC at 40 to 49 years, but the age-related biology is described to little extent. ... -
Long-term risk of arthroplasty and patient-reported outcomes following focal cartilage lesions in the knee
(Doctoral thesis, 2024-11-22)Bakgrunn: Fokale brusklesjoner er vanlige i kneet. Ingen av behandlingsmodaliteten for slike lesjoner er vist å være bedre enn andre. Få studier har rapportert den langsiktige prognosen, og risikoen for påfølgende ... -
Long-Term Outcomes of Arthroscopically Verified Focal Cartilage Lesions in the Knee: A 19-Year Multicenter Follow-up with Patient-Reported Outcomes
(Journal article; Peer reviewed, 2024)Background: Focal cartilage lesions (FCLs) are frequently found during knee arthroscopies and may impair quality of life (QoL) significantly. Several treatment options with good short-term results are available, but the ... -
A Randomised, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial to Evaluate the Biological Effects and Safety of a Polyphenol Supplement on Healthy Ageing
(Journal article; Peer reviewed, 2024)DailyColors™ is a supplement made up of several phytonutrients that aims to replicate elements from the Mediterranean diet. These include fruit, berry and vegetable extracts that are rich in key phytochemicals such as ... -
Kunnskapsoppsummering og klassifisering av tiltaket: Mestringskurs for ungdom (DU) ( 3 utg.)
(Journal article; Peer reviewed, 2024)Bakgrunn: Denne artikkelen er en kunnskapsoppsummering om effektene av Depresjonsmestring for ungdom (DU). Artikkelen er en revisjon av tidligere evalueringer av DU i Ungsinn (Wergeland, Skotheim & Kvello, 2016; Kvello, ... -
Evaluation of dialectical behavior therapy for adolescents in routine clinical practice: a pre-post study
(Journal article; Peer reviewed, 2024)Background Self-harm and suicidal ideation are prevalent among adolescents, cause physical and psychosocial disability, and have potentially life-threatening consequences. Dialectical behavioral therapy for Adolescents ... -
Multi-omics profiling reveals dysregulated ribosome biogenesis and impaired cell proliferation following knockout of CDR2L
(Journal article; Peer reviewed, 2024)Background Cerebellar degeneration-related (CDR) proteins are associated with paraneoplastic cerebellar degeneration (PCD) – a rare, neurodegenerative disease caused by tumour-induced autoimmunity against neural antigens ... -
Genetic associations with psychosis and affective disturbance in Alzheimer's disease
(Journal article; Peer reviewed, 2024)Introduction: Individuals with Alzheimer's disease (AD) commonly experience neuropsychiatric symptoms of psychosis (AD+P) and/or affective disturbance (depression, anxiety, and/or irritability, AD+A). This study's goal was ... -
Platelet transfusions in adult ICU patients with thrombocytopenia: A sub-study of the PLOT-ICU inception cohort study
(Journal article; Peer reviewed, 2024)Background: Platelet transfusions are frequently used in the intensive care unit (ICU), but current practices including used product types, volumes, doses and effects are unknown. Study design and methods: Sub-study of ... -
Holdninger til fysisk aktivitet hos personer i Norge med primær totalprotese i kne eller hofte: En nasjonal spørreundersøkelse
(Journal article; Peer reviewed, 2024)Bakgrunn: I Europa øker andelen proteseoperasjoner. Samtidig går det fysiske aktivitetsnivået i befolkningen ned. Andelen med overvekt og fedme øker. Et transeuropeisk prosjekt for å promotere fysisk aktivitet hos pasienter ... -
Subsequent fracture risk in Norwegians and immigrants with an index forearm fracture: a cohort study
(Journal article; Peer reviewed, 2024)Summary: The current study investigated subsequent fracture risk following a forearm fracture in three country of birth categories: Norway, Europe and North America, and other countries. Subsequent fracture risk was modestly ... -
Stable glioma incidence and increased patient survival over the past two decades in Norway: a nationwide registry-based cohort study
(Journal article; Peer reviewed, 2024)Background: Surveillance of incidence and survival of central nervous system tumors is essential to monitor disease burden and epidemiological changes, and to allocate health care resources. Here, we describe glioma incidence ... -
Activation of Neurotoxic Astrocytes Due to Mitochondrial Dysfunction Triggered by POLG Mutation
(Journal article; Peer reviewed, 2024)Mitochondrial diseases are associated with neuronal death and mtDNA depletion. Astrocytes respond to injury or stimuli and damage to the central nervous system. Neurodegeneration can cause astrocytes to activate and acquire ...