Department of Clinical Medicine
Recent Submissions
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Stroke unit demand in Norway – present and future estimates
(Journal article; Peer reviewed, 2022-03-15)Background: All stroke patients should receive timely admission to a stroke unit (SU). Consequently, most patients with suspected strokes – including stroke mimics (SM) are admitted. The aim of this study was to estimate ... -
Plasma 25 hydroxyvitamin D level and blood gene expression profiles: a cross-sectional study of the Norwegian Women and Cancer Post-genome Cohort
(Journal article; Peer reviewed, 2013)Background/Objectives: Vitamin D deficiency has been associated with increased risk of developing several diseases, but much is unknown about the molecular effects involved. Gene expression technology is increasingly being ... -
Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation
(Journal article; Peer reviewed, 2012)Purpose: To evaluate the efficacy and safety of epithelium-on corneal collagen cross-linking (CXL) using a multifactorial approach to achieve proper stromal riboflavin saturation. Methods: This non-randomized retrospective ... -
Reduced risk of hospitalisation among reported COVID-19 cases infected with the SARS-CoV-2 Omicron BA.1 variant compared with the Delta variant, Norway, December 2021 to January 2022
(Journal article; Peer reviewed, 2022)We included 39,524 COVID-19 Omicron and 51,481 Delta cases reported in Norway from December 2021 to January 2022. We estimated a 73% reduced risk of hospitalisation (adjusted hazard ratio: 0.27; 95% confidence interval: ... -
Intestinal barrier integrity in anorexia nervosa (a pilot study)
(Journal article; Peer reviewed, 2022)Objective There is no conclusive evidence for involvement of intestinal barrier alteration in the etiology of anorexia nervosa (AN). The aims of this pilot study were to identify serum markers of intestinal barrier integrity ... -
Lyme neuroborreliosis with encephalitis; a systematic literature review and a Scandinavian cohort study
(Journal article; Peer reviewed, 2022)Background Lyme neuroborreliosis (LNB) presenting with encephalitis is rare and scarcely described. Objectives To describe the available literature on LNB encephalitis and to characterize this patient group through a ... -
Pneumomediastinum etter sternalpunksjon
(Journal article; Peer reviewed, 2021) -
Detection and significance of small and low proliferation breast cancer
(Journal article; Peer reviewed, 2022)Objectives To determine the frequency and discuss possible implications of early breast cancer with particularly good prognosis and defined by tumor diameter and cell proliferation. Setting Detection of small and ... -
Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children
(Journal article; Peer reviewed, 2016)Background A large proportion of healthy children have wrist changes on MRI, namely carpal depressions, findings that have been described as pathological in children with juvenile idiopathic arthritis. Objective We ... -
Good validity in the Norwegian Knee Ligament Register: assessment of data quality for key variables in primary and revision cruciate ligament reconstructions from 2004 to 2013
(Journal article; Peer reviewed, 2022)Background: The Norwegian Knee Ligament Register was founded in 2004 to provide representative and reliable data on cruciate ligament surgery. The aim of this study was to evaluate the validity of key variables in the ... -
Maternal pregnancy folate status and association to language impairment in children of women with epilepsy after prenatal antiseizure medication exposure
(Doctoral thesis, 2022-05-05)Background: 2-8 out of 1000 pregnancies occur in women with epilepsy. Most women use antiseizure medication (ASM) during pregnancy to avoid potentially harmful epileptic seizures. Fetal exposure to ASM is associated with ... -
Fatal anafylaksi etter tannbehandling
(Journal article, 2021) -
Patient-reported outcome measures after hip fracture in patients with chronic cognitive impairment: results from 34.675 patients in the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2021)Aims: Hip fracture patients have high morbidity and mortality. Patient-reported outcome measures (PROMs) assess the quality of care of patients with hip fracture, including those with chronic cognitive impairment (CCI). ... -
Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells
(Journal article; Peer reviewed, 2021)Prostate cancer (PCa) is the most common non-cutaneous cancer in men and a notable cause of cancer mortality when it metastasises. The unfolded protein response (UPR) can be cytoprotective but when acutely activated can ... -
Nordic guidelines 2021 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
(Journal article; Peer reviewed, 2021)Background The diagnostic work-up and treatment of patients with gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) has undergone major advances and new methods are introduced. Furthermore, an update of the WHO ... -
A Rare Case of Unilateral Renal Cortical Necrosis
(Journal article; Peer reviewed, 2021)Unilateral cortical necrosis is a rare condition, and only described in a few case reports. We present a case of a previously healthy 24-year-old male with acute unilateral cortical necrosis, where contrast-enhanced ... -
A Practical Guide to Modeling and Conducting a Cost-Effectiveness Analysis of Companion Biomarker Tests for Targeted Therapies Using R: Tutorial Paper
(Journal article; Peer reviewed, 2021)Despite the increasing number of potential biomarkers identified in laboratories and reported in much literature, the adoption of biomarkers routinely available in clinical practice to inform treatment decisions is very ... -
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
(Journal article; Peer reviewed, 2021)Prostate cancer is heterogeneous and patients would benefit from methods that stratify those who are likely to respond to systemic therapy. Here, we employ single-cell assays for transposase-accessible chromatin (ATAC) and ...