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  • Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight 

    Iurilli, Maria Laura Caminia; Zhou, Bin; Bennett, James E.; Carrillo-Larco, Rodrigo M.; Sophiea, Marisa K.; Rodriguez-Martinez, Andrea; Bixby, Honor; Solomon, Bethlehem D.; Taddei, Cristina; Danaei, Goodarz; Di Cesare, Mariachiara; Stevens, Gretchen A.; Riley, Leanne M.; Savin, Stefan; Cowan, Melanie J.; Bovet, Pascal; Damasceno, Albertino Antonio Moura; Chirita-Emandi, Adela; Hayes, Alison J; Ikeda, Nayu; Jackson, Rod T.; Khang, Young-Ho; Laxmaiah, Avula; Liu, Jing; Miranda, J. Jaime; Saidi, Olfa; Sebert, Sylvain; Sorić, Maroje; Starc, Gregor; Gregg, Edward W.; Abarca-Gómez, Leandra; Abdeen, Ziad A.; Abdrakhmanova, Shynar; Ghaffar, Suhaila Abdul; Rahim, Hanan Abdul; Abu-Rmeileh, Niveen M.; Garba, Jamila Abubakar; Acosta-Cazares, Benjamin; Adams, Robert J.; Aekplakorn, Wichai; Afsana, Kaosar; Afzal, Shoaib; Agdeppa, Imelda A.; Aghazadeh-Attari, Javad; Aguilar-Salinas, Carlos A.; Agyemang, Charles; Ahmad, Mohamad Hasnan; Ahmad, Noor Ani; Ahmadi, Ali; Ahmadi, Naser; Hassan, Soheir; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Ariansen, Inger Kristine Holtermann; Bergh, Ingunn Holden; Bjertness, Espen; Bjertness, Marius Bergsmark; Ekelund, Ulf; Graff-Iversen, Sidsel; Grøholt, Else Karin; Haugsgjerd, Teresa Risan; Janszky, Imre; Kolle, Elin; Krokstad, Steinar; Madar, Ahmed Ali; Mathiesen, Ellisiv B.; Meisfjord, Jørgen Rajan; Meyer, Haakon Eduard; Sen, Abhijit; Skodje, Gry Irene; Sørgjerd, Elin Pettersen; Sparboe-Nilsen, Bente; Steene-Johannessen, Jostein; Tarp, Jakob; Tell, Grethe S.; Torheim, Liv Elin; Wilsgaard, Tom (Journal article; Peer reviewed, 2021)
    From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated ...
  • Accurate population-based model for individual prediction of colon cancer recurrence 

    Österman, Erik; Ekström, Joakim; Sjöblom, Tobias; Kørner, Hartwig; Myklebust, Tor Åge; Guren, Marianne; Glimelius, Bengt (Journal article; Peer reviewed, 2021)
    Background Prediction models are useful tools in the clinical management of colon cancer patients, particularly when estimating the recurrence rate and, thus, the need for adjuvant treatment. However, the most used models ...
  • Genetic alterations associated with malignant transformation of sporadic vestibular schwannoma 

    Håvik, Aril Løge; Bruland, Ove; Miletic, Hrvoje; Poulsgaard, Lars; Scheie, David; Fugleholm, Kåre; Lund-Johansen, Morten; Knappskog, Per Morten (Journal article; Peer reviewed, 2021)
    Introduction Malignant peripheral nerve sheath tumor of the vestibulocochlear nerve (VN-MPNST) is exceedingly rare and carries a poor prognosis. Little is known about its underlying genetics and in particular the process ...
  • Pulmonary vein isolation in treatment of atrial fibrillation using radiofrequency or cryoballoon ablation: factors associated with better clinical outcomes 

    Shi, Libin (Doctoral thesis, 2022-02-03)
    Background: Electrical pulmonary vein isolation (PVI) is still regarded as a cornerstone for treatment of paroxysmal and persistent atrial fibrillation (AF). It can be achieved by different techniques. We investigated the ...
  • The impacts of contact force, power and application time on ablation effect indicated by serial measurements of impedance drop in both conventional and high-power short-duration ablation settings of atrial fibrillation 

    Shi, Libin; Wang, Yu-Chuan; Chu, Songyun; Bortoli, Alessandro De; Schuster, Peter Moritz; Solheim, Eivind; Chen, Jian (Journal article; Peer reviewed, 2021)
    Background: This study aimed to clarify the interrelationship and additive effects of contact force (CF), power and application time in both conventional and high-power short-duration (HPSD) settings. Methods: Among 38 ...
  • Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs 

    Sønderby, Ida Elken; Ching, Christopher R. K.; Thomopoulos, Sophia I.; van der Meer, Dennis; Sun, Daqiang; Villalon-Reina, Julio E.; Agartz, Ingrid; Amunts, Katrin; Arango, Celso; Armstrong, Nicola J.; Ayesa-Arriola, Rosa; Bakker, Geor; Bassett, Anne S.; Boomsma, Dorret I.; Bulow, Robin; Butcher, Nancy J.; Calhoun, Vince D.; Caspers, Svenja; Chow, Eva W. C.; Cichon, Sven; Ciufolini, Simone; Craig, Michael C.; Crespo-Facorro, Benedicto; Cunningham, Adam C.; Dale, Anders M.; Dazzan, Paola; de Zubicaray, Greig I.; Djurovic, Srdjan; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Durdle, Courtney A.; Ehrlich, Stefan; Emanuel, Beverly S.; Espeseth, Thomas; Fisher, Simon E.; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Gur, Raquel E.; Gutman, Boris A.; Lundervold, Astri J.; Haavik, Jan; Håberg, Asta; Hansen, Laura A.; Moberget, Torgeir; Sánchez, Jennifer Monereo; Reinbold, Céline Sonja; Tamnes, Christian Krog; Westlye, Lars Tjelta; Andreassen, Ole; et al., , (Journal article; Peer reviewed, 2022)
    The Enhancing NeuroImaging Genetics through Meta-Analysis copy number variant (ENIGMA-CNV) and 22q11.2 Deletion Syndrome Working Groups (22q-ENIGMA WGs) were created to gain insight into the involvement of genetic factors ...
  • Identification of pleiotropy at the gene level between psychiatric disorders and related traits 

    Polushina, Tatiana; Banerjee, Niladri; Giddaluru, Sudheer; Bettella, Francesco; Espeseth, Thomas; Lundervold, Astri J.; Djurovic, Srdjan; Cichon, Sven; Hoffmann, Per; Nöthen, Markus M.; Steen, Vidar Martin; Andreassen, Ole A.; Le Hellard, Stéphanie (Journal article; Peer reviewed, 2021)
    Major mental disorders are highly prevalent and make a substantial contribution to the global disease burden. It is known that mental disorders share clinical characteristics, and genome-wide association studies (GWASs) ...
  • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

    Szabo, Attila; O'Connell, Kevin Sean; Ueland, Thor; Sheikh, Mashhood Ahmed; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Journal article; Peer reviewed, 2022)
    Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...
  • Artifacts on Magnetic Resonance Imaging from Electronic Identification Enablement in Silicone Gel Implants Are Not Negligible 

    Kurz, Kathinka Dæhli; Kallevåg, Øystein; Austrått, Kenneth; Styr, Bodil Margrethe; Leiknes, Jon Bjarne; Krøger, Pål (Journal article; Peer reviewed, 2021)
    Breast implants filled with silicone gel are used worldwide for cosmetic reasons, or breast reconstruction following risk-reducing or therapeutic mastectomy. The importance of identifiable implants is undeniable. A recent ...
  • Persistent pulmonary pathology after COVID‑19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase‑9 

    Lerum, Tøri Vigeland; Maltzahn, Niklas; Aukrust, Pål; Trøseid, Marius; Nezvalova-Henriksen, Katerina; Kåsine, Trine; Dyrhol-Riise, Anne Ma; Stiksrud, Birgitte; Haugli, Mette; Blomberg, Bjørn; Kittang, Bård Reiakvam; Johannessen, Asgeir; Hannula, Raisa; Aballi, Saad; Kildal, Anders Benjamin; Eiken, Ragnhild; Dahl, Tuva Børresdatter; Lund-Johansen, Fridtjof; Müller, Fredrik; Rivero, Jezabel Rodriguez; Meltzer, Carin; Einvik, Gunnar; Ueland, Thor; Olsen, Inge Christoffer; Barratt-Due, Andreas; Aaløkken, Trond Mogens; Skjønsberg, Ole Henning (Journal article; Peer reviewed, 2021)
    The association between pulmonary sequelae and markers of disease severity, as well as pro-fibrotic mediators, were studied in 108 patients 3 months after hospital admission for COVID-19. The COPD assessment test (CAT-score), ...
  • Breathing patterns in people with exercise-induced laryngeal obstruction 

    Lie, Astrid Haugen; Grønnevik, Ingvild; Frisk, Bente; Røksund, Ola Drange; Hammer, Ida; Vollsæter, Maria; Halvorsen, Thomas; Clemm, Hege Synnøve Havstad (Journal article; Peer reviewed, 2021)
    Exercise-induced laryngeal obstruction (EILO) is common, but we lack readily available diagnostic tools. The larynx represents an important point of resistance in the airways, and we therefore hypothesized that EILO is ...
  • Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison's Disease 

    Sævik, Åse Bjorvatn; Wolff, Anette Susanne Bøe; Björnsdottir, Sigridur; Simunkova, Katerina; Hynne, Martha Schei; Dolan, David William Peter; Bratland, Eirik; Knappskog, Per M; Methlie, Paal; Carlsen, Siri; Isaksson, Magnus; Bensing, Sophie; Kämpe, Olof; Husebye, Eystein S; Løvås, Kristian; Øksnes, Marianne (Journal article; Peer reviewed, 2021)
    Background No reliable biomarkers exist to guide glucocorticoid (GC) replacement treatment in autoimmune Addison’s disease (AAD), leading to overtreatment with alarming and persistent side effects or undertreatment, which ...
  • Sex-Specific Limitations in Physical Health in Primary Adrenal Insufficiency 

    Didriksen, Nora Møller; Sævik, Åse Bjorvatn; Sortland, Linn Solveig; Øksnes, Marianne; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2021)
    Background: Patients with primary adrenal insufficiency (PAI) suffer reduced quality of life (QoL), but comparisons with large-scale normative data are scarce. The clinical characteristics associated with reduced QoL are ...
  • Sleep and physical activity from before conception to the end of pregnancy in healthy women: a longitudinal actigraphy study 

    Vietheer, Alexander; Kiserud, Torvid; Lie, Rolv Terje; Haaland, Øystein Ariansen; Kessler, Jörg (Journal article; Peer reviewed, 2021)
    Background Sleep and physical activity changes are common in pregnancy, but longitudinal data starting before conception are scarce. Our aim was to determine the changes of the daily total sleep time (TST) and physical ...
  • Role of Adipocyte SLC7A10 and Amino Acid Metabolism in Obesity and Insulin Resistance 

    Jersin, Regine Åsen (Doctoral thesis, 2020-12-18)
    Obesity is a rising global concern, associated with increased risk of developing metabolic syndrome, insulin resistance and type 2 diabetes. Chronic availability of excess nutrients may promote adipocyte dysfunction, ...
  • The effect of Zhang’s guideline versus the WHO partograph on childbirth experience measured by the Childbirth Experience Questionnaire in the Labor Progression Study (LaPS): A cluster randomized trial 

    Rozsa, Daniella Judit; Dalbye, Rebecka; Bernitz, Stine; Blix, Ellen; Dalen, Ingvild; Braut, Geir Sverre; Eggebø, Torbjørn Moe; Øian, Pål; Sande, Ragnar Kvie (Journal article; Peer reviewed, 2021)
    Introduction Childbirth experience is an increasingly recognized and important measure of quality of obstetric care. Previous research has shown that it can be affected by intrapartum care and how labor is followed. A ...
  • A radiogenomics application for prognostic profiling of endometrial cancer 

    Høivik, Erling Andre; Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Fasmer, Kristine Eldevik; Berg, Hege Fredriksen; Halle, Mari Kyllesø; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)
    Prognostication is critical for accurate diagnosis and tailored treatment in endometrial cancer (EC). We employed radiogenomics to integrate preoperative magnetic resonance imaging (MRI, n = 487 patients) with histologic-, ...
  • Age-related differences in self-report and objective measures of cognitive function in older patients prior to chemotherapy 

    Utne, Inger; Løyland, Borghild; Grov, Ellen Karine; Rasmussen, Hege Lund; Torstveit, Ann Helen; Paul, Steven M.; Lindemann, Kristina Yvonne Kathe; Vistad, Ingvild; Rodriguez-Aranda, Claudia; Miaskowski, Christine (Journal article; Peer reviewed, 2021)
    Aim Evaluate for differences in demographic and clinical characteristics and subjective and objective measures of cognitive function (CF) between younger older adults (YOA, 60–69 years) and older adults (OA, ≥70 ...
  • A gene signature identifying CIN3 regression and cervical cancer survival 

    Halle, Mari Kyllesø; Munk, Ane Cecilie Dæhli; Engesæter, Birgit Øvstebø; Akbari, Saleha; Frafjord, Astri; Høivik, Erling Andre; Forsse, David Erik; Fasmer, Kristine Eldevik; Woie, Kathrine; Haldorsen, Ingfrid S.; Bertelsen, Bjørn; Janssen, Emiel; Gudlaugsson, Einar; Krakstad, Camilla; Øvestad, Irene Tveiterås (Journal article; Peer reviewed, 2021-11-16)
    The purpose of this study was to establish a gene signature that may predict CIN3 regression and that may aid in selecting patients who may safely refrain from conization. Oncomine mRNA data including 398 immune-related ...
  • Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health 

    Johannessen, Jarle; Nærland, Terje; Hope, Sigrun; Torske, Tonje; Kaale, Anett; Wirgenes, Katrine V.; Malt, Eva; Djurovic, Srdjan; Rietschel, Marcella; Andreassen, Ole A. (Journal article; Peer reviewed, 2021)
    Clinical relevance of genetic testing is increasing in autism spectrum disorder (ASD). Information about genetic risk may contribute to improved diagnostics, treatment and family planning, but may also be perceived as a ...

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