Department of Clinical Science
Recent Submissions
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Autoimmune Thyroid Disorders in Autoimmune Addison Disease
(Journal article; Peer reviewed, 2022)Context: Autoimmune thyroid disease is the most common endocrine co-morbidity in autoimmune Addison's disease (AAD), but detailed investigations of prevalence and clinical course is lacking. Objective: Provide comprehensive ... -
Left vocal cord paralysis, lung function and exercise capacity in young adults born extremely preterm with a history of neonatal patent ductus arteriosus surgery—A national cohort study
(Journal article; Peer reviewed, 2022-01-03)Background: Left vocal cord paralysis (LVCP) is a known complication of patent ductus arteriosus (PDA) surgery in extremely preterm (EP) born neonates; however, consequences of LVCP beyond the first year of life are ... -
Increased risk of atrial fibrillation among elderly Norwegian men with a history of long-term endurance sport practice
(Journal article; Peer reviewed, 2014)Atrial fibrillation (AF) is the most common cardiac arrhythmia. The prevalence increases with increasing age. In middle-aged men, endurance sport practice is associated with increased risk of AF but there are few studies ... -
Physical activity and exercise capacity in survivors of preterm birth : A population-based cohort study of long-term consequences of prematurity
(Doctoral thesis, 2022-05-19)Background: Physical activity (PA) is an important mediator of health. Extremely preterm (EP) (<28 weeks’ gestation) and extremely low birth weight (ELBW) (<1000 g) subjects are at increased risk of long-term sequelae that ... -
Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer
(Journal article; Peer reviewed, 2012)Background: The objective of this study was to assess markers of spermatogenesis in long-term survivors of testicular cancer (TC) according to treatment, and to explore correlations between the markers and associations ... -
Vinorelbine and gemcitabine vs vinorelbine and carboplatin as first-line treatment of advanced NSCLC. A phase III randomised controlled trial by the Norwegian Lung Cancer Study Group
(Journal article; Peer reviewed, 2012)Background: Platinum-based doublet chemotherapy is the standard first-line treatment for advanced non-small cell lung cancer (NSCLC), but earlier studies have suggested that non-platinum combinations are equally effective ... -
Modeling assortative mating and genetic similarities between partners, siblings, and in-laws
(Journal article; Peer reviewed, 2022)Assortative mating on heritable traits can have implications for the genetic resemblance between siblings and in-laws in succeeding generations. We studied polygenic scores and phenotypic data from pairs of partners ... -
A nationwide school fruit and vegetable policy and childhood and adolescent overweight: A quasi-natural experimental study
(Journal article; Peer reviewed, 2022)Background School free fruit and vegetable (FFV) policies are used to promote healthy dietary habits and tackle obesity; however, our understanding of their effects on weight outcomes is limited. We assess the effect of ... -
Hva består oksymetriparametrene på blodgassutskriften av?
(Journal article, 2022) -
Oral health-related interdisciplinary practices among healthcare professionals in Saudi Arabia: Does integrated care exist?
(Journal article; Peer reviewed, 2022)Background There is a bidirectional relation between oral and general health, therefore collaboration between healthcare providers is needed. This study investigated current interdisciplinary practices (IDP) and the ... -
Early life growth and associations with lung function and bronchial hyperresponsiveness at 11-years of age
(Journal article; Peer reviewed, 2021)Low birthweight and being born small-for-gestational age (SGA) are linked to asthma and impaired lung function. Particularly, poor intrauterine growth followed by rapid catch-up growth during childhood may predispose for ... -
Major increase in microbiota-dependent proatherogenic metabolite TMAO one year after bariatric surgery
(Journal article; Peer reviewed, 2016)Background: Trimethylamine-N-oxide (TMAO) is formed in the liver from trimethylamine (TMA), a product exclusively generated by the gut microbiota from dietary phosphatidylcholine and carnitine. An alternative pathway of ... -
Genetics of vestibular schwannoma : Genetic landscape of irradiated and radiation-naïve benign and malignant vestibular schwannoma
(Doctoral thesis, 2022-05-06)Background: Vestibular schwannoma (VS) is a benign intracranial neoplasm associated with reduced quality of life. Malignant peripheral nerve sheath tumor of the vestibular nerve (VN-MPNST) is the malignant counterpart, an ... -
Presence of interferon-λ 4, male gender, absent/mild steatosis and low viral load augment antibody levels to hepatitis C virus
(Journal article; Peer reviewed, 2021)Objectives Despite recombinant interferon-λ 4 (IFN-λ4) demonstrating anti-viral activity in vitro and the ancestral functional gene (IFNL4) being conserved in all other primates, there has been speculation that IFN-λ4 may ... -
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
(Journal article; Peer reviewed, 2021)T cells rely for their development and function on the correct folding and turnover of proteins generated in response to a broad range of molecular cues. In the absence of the eukaryotic type II chaperonin complex, CCT, T ... -
Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
(Journal article; Peer reviewed, 2021)The value of high-throughput germline genetic testing is increasingly recognized inclinical cancer care. Disease-associated germline variants in cancer patients areimportant for risk management and surveillance, surgical ... -
Hypertension in women: Should there be a sex-specific threshold?
(Journal article; Peer reviewed, 2021)Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more ... -
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
(Journal article; Peer reviewed, 2022)Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic ... -
Impact of hormonal biomarkers on response to hormonal therapy in advanced and recurrent endometrial cancer
(Journal article; Peer reviewed, 2021)Background Approximately 20% of women with endometrial cancer have advanced-stage disease or suffer from a recurrence. For these women, prognosis is poor, and palliative treatment options include hormonal therapy and ... -
Identification and functional characterization of a novel susceptibility locus for small vessel vasculitis with MPO-ANCA
(Journal article; Peer reviewed, 2021)Objective To identify and characterize genetic loci associated with the risk of developing ANCA-associated vasculitides (AAV). Methods Genetic association analyses were performed after Illumina sequencing of 1853 genes ...
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