• MRI adipose tissue segmentation and quantification in R (RAdipoSeg) 

  Haugen, Christine; Lysne, Vegard; Haldorsen, Ingfrid S.; Tjora, Erling; Gudbrandsen, Oddrun Anita; Sagen, Jørn Vegard; Dankel, Simon N; Mellgren, Gunnar (Journal article; Peer reviewed, 2022-10-08)

  Background: Excess adipose tissue is associated with increased cardiovascular and metabolic risk, but the volume of visceral and subcutaneous adipose tissue poses different metabolic risks. MRI with fat suppression can be ...

• Impact of rapid molecular testing on diagnosis, treatment and management of community-acquired pneumonia in Norway: a pragmatic randomised controlled trial (CAPNOR) 

  Serigstad, Sondre; Ritz, Christian; Faurholt-Jepsen, Daniel; Markussen, Dagfinn Lunde; Ebbesen, Marit Helen; Kommedal, Øyvind; Bjørneklett, Rune Oskar; Heggelund, Lars; Clark, Tristan W.; van Werkhoven, Cornelis H.; Knoop, Siri Tandberg; Ulvestad, Elling; Grewal, Harleen (Journal article; Peer reviewed, 2022)

  Background: Community-acquired pneumonia (CAP) causes a large burden of disease. Due to difficulties in obtaining representative respiratory samples and insensitive standard microbiological methods, the microbiological ...

• Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment 

  Aamdal, Elin; Skovlund, Eva; Jacobsen, Kari Dolven; Straume, Oddbjørn; Kersten, Christian; Herlofsen, Oluf; Karlsen, Jarle; Hussain, Israr; Amundsen, Anita; Dalhaug, Astrid; Nyakas, Marta Sølvi; Hagene, Kirsten Thorin; Holmsen, Kjersti; Aamdal, Steinar; Kaasa, Stein; Guren, Tormod Kyrre; Kyte, Jon A (Journal article; Peer reviewed, 2022)

  Background: We have previously reported that the safety and efficacy of ipilimumab in real-world patients with metastatic melanoma were comparable to clinical trials. Few studies have explored health-related quality of ...

• Cohort profile: the Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) - a national research and quality registry with a biomaterial collection 

  Medbøen, Ingrid Tøndel; Persson, Karin Ester Torun; Nåvik, Marit; Totland, Torunn Holm; Bergh, Sverre; Treviño, Cathrine Selnes; Ulstein, Ingun; Engedal, Knut; Knapskog, Anne Brita; Brækhus, Anne; Øksengård, Anne Rita; Horndalsveen, Peter Otto; Saltvedt, Ingvild; Lyngroth, Anne Liv; Ranhoff, Anette Hylen; Skrettingland, Dagny B; Naik, Mala; Soares, Jelena Zugic; Johnsen, Bente; Selbæk, Geir (Journal article; Peer reviewed, 2022)

  Purpose: The Norwegian Registry of Persons Assessed for Cognitive Symptoms (NorCog) was established to harmonise and improve the quality of diagnostic practice across clinics assessing persons with cognitive symptoms in ...

• Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study 

  Reigstad, Hallvard; Hufthammer, Karl Ove; Rønnestad, Arild Erland; Klingenberg, Claus Andreas; Stensvold, Hans Jørgen; Markestad, Trond Jacob (Journal article; Peer reviewed, 2022)

  Objective: To compare outcome after less invasive surfactant administration (LISA) and primary endotracheal intubation (non-LISA) in infants born before gestational age (GA) 28 weeks. Setting: All neonatal intensive ...

• Predictors of long-term symptom burden and quality of life in patients hospitalised with chest pain: a prospective observational study 

  Saeed, Nasir; Norekvål, Tone Merete; Steiro, Ole-Thomas; Tjora, Hilde Lunde; Langørgen, Jørund; Bjørneklett, Rune Oskar; Skadberg, Øyvind; Bonarjee, Vernon V S; Mjelva, Øistein; Omland, Torbjørn; Vikenes, Kjell; Aakre, Kristin Moberg (Journal article; Peer reviewed, 2022)

  Objective: To describe the magnitude and predictors of symptom burden (SB) and quality of life (QoL) 3 months after hospital admission for acute chest pain. Design: Prospective observational study. Setting: Single ...

• Sex differences in blood pressure in midlife: associations with risk factors and acute coronary syndromes in the Hordaland Health Studies 

  Kringeland, Ester Anne (Doctoral thesis, 2022-12-06)

  Bakgrunn: Blant unge voksne har friske kvinner vanligvis lavere blodtrykk (BT) enn menn. Men allerede fra 20-årene har kvinner en brattere stigning i BT enn menn på samme alder. Målet med dette arbeidet var å identifisere ...

• Inflammation, sex, blood pressure changes and hypertension in midlife: the Hordaland Health Study 

  Kringeland, Ester Anne; Gerdts, Eva; Ulvik, Arve; Tell, Grethe S.; Igland, Jannicke; Haugsgjerd, Teresa Risan; Ueland, Per Magne; Midtbø, Helga Bergljot (Journal article; Peer reviewed, 2022)

  Our aim was to test sex-specific associations of circulating markers of inflammation with blood pressure (BP) and incident hypertension in midlife. Participants in the Hordaland Health study (n = 3280, 56% women, mean age ...

• Associations between biological maturity level, match locomotion, and physical capacities in youth male soccer players 

  Gundersen, Hilde; Riiser, Amund; Algrøy, Erling Andre; Vestbøstad, Mona; Sæterbakken, Atle Hole; Clemm, Hege Synnøve Havstad; Grendstad, Halvard; Hafstad, Arild; Kristoffersen, Morten; Rygh, Cecilie Brekke (Journal article; Peer reviewed, 2022)

  Introduction: Biological maturity level has shown to affect sport performance in youths. However, most previous studies have used noninvasive methods to estimate maturity level. Thus, the main aim of the present study was ...

• Detailed stratified GWAS analysis for severe COVID-19 in four European populations 

  Degenhardt, Frauke; Ellinghaus, David; Juzenas, Simonas; Lerga-Jaso, Jon; Wendorff, Mareike; Maya-Miles, Douglas; Uellendahl-Werth, Florian; ElAbd, Hesham; Lenning, Ole Bernt; Myhre, Ronny; Vadla, May Sissel; Holten, Aleksander Rygh; Kildal, Anders Benjamin; Lind, Andreas; Dyrhol-Riise, Anne Ma; Hoff, Dag Arne Lihaug; Müller, Fredrik; Solligård, Erik; Holter, Jan Cato; Afset, Jan Egil; Damås, Jan Kristian; Bergan, Jonas; Risnes, Kari; Muller, Karl Erik; Tonby, Kristian; Heggelund, Lars; Gustad, Lise Tuset; Grimsrud, Marit Mæhle; Dudman, Susanne Gjeruldsen; Folseraas, Trine; Skogen, Vegard; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Rühlemann, Malte C.; Arora, Jatin; Özer, Onur; Wacker, Eike Matthias; Wienbrandt, Lars; Ortiz, Aron Blandino; de Salazar, Adolfo; Chercoles, Adolfo Garrido; Palom, Adriana; Ruiz, Agustin; Garzia-Fernandez, Alba-Estela; Blanco-Grau, Albert; Mantovani, Alberto; Zanella, Alberto; Mayer, Alena; Bandera, Alessandra; Franke, Andre (Journal article; Peer reviewed, 2022)

  Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease ...

• The alarmins high mobility group box protein 1 and S100A8/A9 display different inflammatory profiles after acute knee injury 

  Aulin, C.; Larsson, S.; Vogl, T.; Roth, J.; Åkesson, A.; Swärd, P.; Heinbäck, R.; Harris, Helena Erlandsson; Struglics, A. (Journal article; Peer reviewed, 2022)

  Objective To compare the concentrations of high mobility group box 1 protein (HMGB1) and S100A8/A9 in synovial fluid between patients with knee injuries and osteoarthritis (OA), and knee healthy subjects. To investigate ...

• Tidal breathing parameters in extremely premature infants. Feasibility and clinical utility of electromagnetic inductance plethysmography 

  Bentsen, Mariann Haavik Lysfjord (Doctoral thesis, 2018-09-06)

  Background: Extremely preterm (EP) birth is associated with adverse lung growth, due to disturbance of programmed and fine-tuned sequences of normal intrauterine development, as well as the trauma inflicted by life-saving ...

• Ventilator flow data predict bronchopulmonary dysplasia in extremely premature neonates 

  Bentsen, Mariann; Markestad, Trond; Halvorsen, Thomas (Journal article; Peer reviewed, 2018)

  Early prediction of bronchopulmonary dysplasia (BPD) may facilitate tailored management for neonates at risk. We investigated whether easily accessible flow data from a mechanical ventilator can predict BPD in neonates ...

• Consequences of refining biological networks through detailed pathway information : From genes to proteoforms 

  Hernández Sánchez, Luis Francisco (Doctoral thesis, 2022-11-28)

  Biologiske nettverk kan brukes til å modellere molekylære prosesser, forstå sykdomsprogresjon og finne nye behandlingsstrategier. Denne avhandlingen har undersøkt hvordan utformingen av slike nettverk påvirker deres struktur, ...

• Lung function at term in extremely preterm-born infants: A regional prospective cohort study 

  Bentsen, Mariann; Markestad, Trond; Øymar, Knut; Halvorsen, Thomas (Journal article; Peer reviewed, 2017)

  Objectives: To compare lung function of extremely preterm (EP)-born infants with and without bronchopulmonary dysplasia (BPD) with that of healthy term-born infants, and to determine which perinatal characteristics were ...

• Electromagnetic inductance plethysmography is well suited to measure tidal breathing in infants 

  Bentsen, Mariann; Eriksen, Morten; Olsen, Merete Susan; Markestad, Trond; Halvorsen, Thomas (Journal article; Peer reviewed, 2016)

  Reliable, accurate and noninvasive methods for measuring lung function in infants are desirable. Electromagnetic inductance plethysmography has been used to perform infant spirometry and VoluSense Pediatrics (VSP) (VoluSense, ...

• Point-of-care influenza testing impacts clinical decision, patient flow and length of stay in hospitalized adults 

  Fjelltveit, Elisabeth Berg; Brokstad, Rebecca Jane Cox; Østensjø, Jørgen; Blomberg, Bjørn; Ebbesen, Marit Helen; Langeland, Nina; Mohn, Kristin Greve Isdahl (Journal article; Peer reviewed, 2022)

  Background Influenza is difficult to distinguish clinically from other acute respiratory infections. Rapid laboratory diagnosis can help initiate early effective antiviral treatment and isolation. Implementing a novel ...

• Clinical studies of epidemic influenza and pandemic COVID-19 to improve the chain of patient care: from bedside diagnostics to long-term complications : 

  Fjelltveit, Elisabeth Berg (Doctoral thesis, 2022-11-29)

  Tidlig diagnostikk og rask og målrettet behandling kan forbedre utfallet av influensa og Covid-19 sykdom. Gjennom prospektive, kontrollerte observasjonsstudier har vi vist betydningen av rask diagnostikk for å redusere ...

• Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete' 

  Clemm, Hege Synnøve Havstad; Olin, J Tod; McIntosh, Cameron; Schwellnus, Martin; Sewry, Nicola; Hull, James H.; Halvorsen, Thomas (Journal article; Peer reviewed, 2022)

  Exercise-induced laryngeal obstruction (EILO) is caused by paradoxical inspiratory adduction of laryngeal structures during exercise. EILO is an important cause of upper airway dysfunction in young individuals and athletes, ...

• Circulating trimethylamine N-oxide levels do not predict 10-year survival in patients with or without coronary heart disease 

  Bjørnestad, Espen Øglænd; Dhar, Indu; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Kristine Ringdal; Ørn, Stein; Svenningsson, Mads Malm; Tell, Grethe Seppola; Ueland, Per Magne; Sulo, Gerhard; Laaksonen, Reijo; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2022)

  Background Trimethylamine N-oxide (TMAO) is an amine oxide generated by gut microbial metabolism. TMAO may contribute to atherothrombosis and systemic inflammation. However, the prognostic value of circulating TMAO for ...

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