• Thyroidectomy for Euthyroid Patients with Hashimoto Disease and Persistent Symptoms: An Observational, Postrandomization Study 

  Hoff, Geir Svein; Bernklev, Tomm; Johnsen, Lene; Reitsma, Laurens Cornelus; Sina, Dirk; Lauzike, Andromeda; Gibbs, Charlotte Christine; Lende, Tone Hoel; Narvestad, Jon Kristian; Kildahl, Rasmus; Omdal, Roald; Kvaløy, Jan Terje; Søiland, Håvard (Journal article; Peer reviewed, 2024)

  Background: Despite adequate hormone substitution in Hashimoto disease, some patients may have persistent symptoms with a possible autoimmune pathophysiology. A recent randomized trial (RCT) using patient-reported outcome ...

• Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review 

  Felton, Jamie L.; Redondo, Maria J.; Oram, Richard A.; Speake, Cate; Long, S. Alice; Onengut-Gumuscu, Suna; Rich, Stephen S.; Monaco, Gabriela S. F.; Harris-Kawano, Arianna; Perez, Dianna; Saeed, Zeb; Hoag, Benjamin; Jain, Rashmi; Evans-Molina, Carmella; DiMeglio, Linda A.; Ismail, Heba M.; Dabelea, Dana; Johnson, Randi K.; Urazbayeva, Marzhan; Wentworth, John M.; Griffin, Kurt J.; Sims, Emily K.; Franks, Paul W.; Rich, Stephen S.; Wagner, Robert; Vilsbøll, Tina; Vesco, Kimberly K.; Udler, Miriam S.; Tuomi, Tiinamaija; Sweeting, Arianne; Sims, Emily K.; Sherr, Jennifer L.; Semple, Robert K.; Reynolds, Rebecca M.; Redman, Leanne M.; Pratley, Richard E.; Pop-Busui, Rodica; Pollin, Toni I.; Perng, Wei; Pearson, Ewan R.; Ozanne, Susan E.; Owen, Katharine R.; Oram, Richard; Murphy, Rinki; Mohan, Viswanathan; Misra, Shivani; Meigs, James B.; Mathioudakis, Nestoras; Mathieu, Chantal; Ma, Ronald C. W.; Loos, Ruth J. F.; Lim, Siew S.; Laffel, Lori M.; Kwak, Soo Heon; Josefson, Jami L.; Hood, Korey K.; Hivert, Marie-France; Hirsch, Irl B.; Hattersley, Andrew T.; Griffin, Kurt; Greeley, Siri Atma W.; Gottlieb, Peter A.; Gomez, Maria F.; Gloyn, Anna L.; Florez, Jose C.; Dennis, John M.; Costacou, Tina; Boyle, Kristen; Billings, Liana K.; Brown, Rebecca J.; Philipson, Louis H.; Nolan, John J.; Eckel, Robert H.; Sherifali, Diana; Mixter, Emily; Mekonnen, Eskedar Getie; Gruber, Chandra; Fawcett, Andrea J.; de Souza, Russell; Auh, Sungyoung; Zhu, Yeyi; Zhang, Cuilin; Saint-Martin, Cécile; Provenzano, Michele; Pomares-Millan, Hugo; Njølstad, Pål Rasmus; Nakabuye, Mariam; Molnes, Janne; McGovern, Andrew; Maloney, Kristin A.; Flanagan, Sarah E.; de Franco, Elisa; Aukrust, Ingvild; Polak, Michel; Beltrand, Jacques; Zhou, Shao J.; Zhang, Yingchai; Yu, Gechang; White, Sara L.; Hannah, Wesley; Vatier, Camille; Van der Schueren, Bart; Ukke, Gebresilasea Gendisha; Tye, Sok Cin; Taylor, Rachael; Støy, Julie; Stefan, Norbert; Steck, Andrea K.; Steenackers, Nele; Stanislawski, Maggie A.; Sheu, Wayne Huey-Herng; Selvin, Elizabeth; Scholtens, Denise M.; Sarkar, Sudipa; Kanbour, Sarah; Santhakumar, Vanessa; Ried-Larsen, Mathias; Ray, Debashree; Quinteros, Alejandra; Powe, Camille E.; Petrie, John R.; Perez, Dianna; Pazmino, Sofia; Pathirana, Maleesa; Pankow, James S.; Onengut-Gumuscu, Suna; Motala, Ayesha A.; Morton, Robert W.; Lowe, William L.; Liu, Kai; Libman, Ingrid M.; Leung, Gloria K. W.; Leong, Aaron; Koivula, Robert W.; Jones, Angus G.; Huang, Chuiguo; Hansen, Torben; Habibi, Nahal; Guasch-Ferré, Marta; Grieger, Jessica A.; Goodarzi, Mark O.; Gitelman, Stephen E.; Fitzpatrick, Stephanie L.; Fitipaldi, Hugo; Fernández-Balsells, María Mercè; Dudenhöffer-Pfeifer, Monika; DiMeglio, Linda A.; Dickens, Laura T.; Deutsch, Aaron J.; Dawed, Adem Y.; Clemmensen, Christoffer; Chivers, Sian C.; Chikowore, Tinashe; Cheng, Feifei; Chen, Mingling; Bonham, Maxine P.; Andersen, Mette K.; Amouyal, Chloé; Young, Katherine; Yamamoto, Jennifer M.; Wong, Jessie J.; Wang, Caroline C.; Wallace, Amelia S.; Tosur, Mustafa; Thuesen, Anne Cathrine B.; Tam, Claudia Ha-ting; Takele, Wubet Worku; Sevilla-Gonzalez, Magdalena; Semnani-Azad, Zhila; Schön, Martin; Rooney, Mary R.; Raghavan, Sridharan; Prystupa, Katsiaryna; Pilla, Scott J.; Patel, Kashyap Amratlal; Ozkan, Bige; Naylor, Rochelle N.; Most, Jasper; Morieri, Mario Luca; Miller, Rachel G.; Mclennan, Niamh-Maire; Massey, Robert; Männistö, Jonna M. E.; Lim, Lee-Ling; Kreienkamp, Raymond J.; Kettunen, Jarno L. T.; Kahkoska, Anna R.; Jacobsen, Laura M.; Ikle, Jennifer M.; Hughes, Alice; Haider, Eram; Gaillard, Romy; Gingras, Véronique; Gillard, Pieter; Francis, Ellen C.; Felton, Jamie L.; Duan, Daisy; Cromer, Sara J.; Corcoy, Rosa; Colclough, Kevin; Clark, Amy L.; Bodhini, Dhanasekaran; Benham, Jamie L.; Aiken, Catherine; Ahmad, Abrar; Merino, Jordi; Tobias, Deirdre K.; Svalastoga, Pernille (Journal article; Peer reviewed, 2024)

  Background Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify ...

• Clinical and imaging characteristics of patients with cardiac amyloidosis- a single center observational study 

  Ingebrigtsen, Andreas; Saeed, Sahrai; Larsen, Terje Hjalmar; Reikvam, Håkon (Journal article; Peer reviewed, 2024)

  Amyloidosis is a disease characterized by the deposition of protein fibrils. Cardiac involvement is a significant factor in determining prognosis. This study aimed to examine the clinical profile, outcomes, and long-term ...

• Obstetric infections and clinical characteristics of maternal sepsis: a hospital-based retrospective cohort study 

  Kvalvik, Sedina Atic; Zakariassen, Sofie Branæs; Overrein, Sofie; Rasmussen, Svein; Skrede, Steinar; Baghestan, Elham (Journal article; Peer reviewed, 2024)

  Sepsis is responsible for 50% of intrahospital maternal deaths worldwide. Incidence is increasing in both low and middle-, and high-income countries. There is little data on incidence and clinical outcomes of obstetric ...

• Immune cell activity during anti-TNF treatment in patients with psoriasis and psoriatic arthritis 

  Petrovic, Aleksandra; Samuelsen-Fossen, Victoria Marie; Davies, Richard Allan; Aarebrot, Anders; Holmes, Timothy Dunstan; Sarkar, Irene; Bergum, Brith; Jonsson, Roland; Sandvik, Lene Frøyen; Solberg, Silje Michelsen; Appel, Silke (Journal article; Peer reviewed, 2024)

  Psoriasis is a chronic, inflammatory skin disease characterized by a dysregulated immune response and systemic inflammation. Up to one-third of patients with psoriasis have psoriatic arthritis (PsA). Targeted treatment ...

• Discharge Information About Adverse Drug Reactions Indicates Lower Self-Reported Adverse Drug Reactions and Fewer Concerns in Patients After Percutaneous Coronary Intervention 

  Pettersen, Trond Røed; Schjøtt, Jan Didrik; Allore, Heather; Bendz, Bjørn; Borregaard, Britt; Fridlund, Bengt; Hadjistavropoulos, Heather; Larsen, Alf Inge; Nordrehaug, Jan Erik; Rasmussen, Trine Bernholdt; Rotevatn, Svein; Valaker, Irene; Wentzel-Larsen, Tore; Norekvål, Tone Merete (Journal article; Peer reviewed, 2024)

  Aim There are discrepancies between the information patients desire about adverse drug reactions (ADRs) and the information they receive from healthcare providers; this is an impediment to shared decision-making. This study ...

• Clinical utility of novel diabetes subgroups in predicting vascular complications and mortality: up to 25 years of follow-up of the HUNT Study 

  Bjarkø, Vera Vik; Haug, Eirin Beate; Langhammer, Arnulf; Lopez-Doriga Ruiz, Paz; Carlsson, Sofia; Birkeland, Kåre Inge; Berg, Tore Julsrud; Sørgjerd, Elin Pettersen; Lyssenko, Valeriya; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2024)

  Introduction Cluster analysis has previously revealed five reproducible subgroups of diabetes, differing in risks of diabetic complications. We aimed to examine the clusters’ predictive ability for vascular complications ...

• Development of selective ssDNA micro-probe for PD1 detection as a novel strategy for cancer imaging 

  Malicki, Stanisław; Czarna, Anna; Żyła, Edyta; Pucelik, Barbara; Gałan, Wojciech; Chruścicka, Barbara; Kaminska, Marta; Sochaj-Gregorczyk, Alicja; Magiera-Mularz, Katarzyna; Wang, Jun; Winiarski, Marek; Benedyk-Machaczka, Małgorzata; Kozieł, Joanna; Dubin, Grzegorz; Mydel, Piotr Mateusz (Journal article; Peer reviewed, 2024)

  Programmed death receptor 1, PD1, modulates the function of immune cells by providing inhibitory signals and constitutes the marker of immune exhaustion. Monitoring the level of PD1 promises a useful diagnostic approach ...

• Elastic Bands Improve Oral Appliance Treatment Effect on Obstructive Sleep Apnoea: A Randomised Crossover Trial 

  Opsahl, Ulrik Leidland; Berge, Morten Eirik; Lehmann, Sverre; Bjorvatn, Bjørn; Johansson, Anders (Journal article; Peer reviewed, 2024)

  Background Oral appliances (OAs) that limit mouth opening during sleep, such as monobloc appliances, have shown superior treatment effects in subgroups of patients with obstructive sleep apnoea. The application of elastic ...

• Toxoplasma gondii infection associated with inflammasome activation and neuronal injury 

  Andreou, Dimitrios; Steen, Nils Eiel; Mørch-Johnsen, Lynn Egeland; Jørgensen, Kjetil Nordbø; Wortinger, Laura Anne; Barth, Claudia; Szabo, Attila; O'Connell, Kevin Sean; Lekva, Tove; Hjell, Gabriela; Johansen, Ingrid Torp; Ormerod, Monica Bettina E. Greenwood; Haukvik, Unn Kristin Hansen; Aukrust, Pål; Djurovic, Srdjan; Yolken, Robert H.; Andreassen, Ole A.; Ueland, Thor; Agartz, Ingrid (Journal article; Peer reviewed, 2024)

  Toxoplasma gondii (TOXO) infection typically results in chronic latency due to its ability to form cysts in the brain and other organs. Latent toxoplasmosis could promote innate immune responses and impact brain function. ...

• Randomized clinical trial to assess whether the duration of cotrimoxazole preventive therapy in HIV patients with CD4 counts >350 CD4 cells/μL by antiretroviral treatment influences the rate of carriage of multidrug-resistant bacteria. Study protocol 

  Blomberg, Bjørn; Aboud, Said; Aamodt, Håvard; Manyahi, Joel; Moyo, Sabrina J.; Tellevik, Marit Gjerde; Langeland, Nina (Report, 2016-09-20)

  Cotrimoxazole preventive therapy (CPT) is recommended for prevention of morbidity and mortality due to Pneumocystis jirovecii pneumonia (PJP) and other infections in HIV positive patients with low immunity. In industrial ...

• Nekrotiserende bløtdelsinfeksjoner 

  Gundersen, Ingunn; Bruun, Trond; Almeland, Stian Kreken; Skutlaberg, Dag Harald; Nedrebø, Torbjørn; Rath, Eivind; Oppegaard, Oddvar; Guttormsen, Anne Berit; Norrby-Teglund, Anna; Mosevoll, Knut Anders; Skrede, Steinar (Journal article; Peer reviewed, 2024)

  Nekrotiserende bløtdelsinfeksjoner rammer hud, subkutant vev, overfladisk fascie, dyp fascie eller muskulatur. Infeksjonene er alvorlige, sprer seg hurtig og kan medføre omfattende vevstap. De er sjeldne, men har høy ...

• 'If you've lost your personality, there's no point in changing the valve'-a qualitative study of older adults' attitudes towards treatment of aortic stenosis with comorbid dementia 

  Skaar, Elisabeth; Rostoft, Siri; Cruz-Jentoft, Alfonso; Jackson, Thomas; Bleie, Øyvind; Packer, Erik; Øksnes, Anja; Schaufel, Margrethe Aase (Journal article; Peer reviewed, 2024)

  Objectives Due to prognostic uncertainty and limited decision-making capacity, the choice to perform transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis (AS) and comorbid dementia is ...

• Pre-pregnancy obesity among immigrant and non-immigrant women in Norway: Prevalence, trends, and subgroup variations 

  Nilsen, Roy Miodini; Strandberg, Ragnhild Bjarkøy; Yaya, Yaliso; Fismen, Anne-Siri; Macsali, Ferenc; Morken, Nils-Halvdan; Gomez Real, Francisco; Schytt, Erica; Skirnisdottir Vik, Eline; Sørbye, Linn Marie (Journal article; Peer reviewed, 2024)

  Introduction This study assessed prevalence and time trends of pre-pregnancy obesity in immigrant and non-immigrant women in Norway and explored the impact of immigrants' length of residence on pre-pregnancy obesity ...

• Rare copy number variant analysis in case–control studies using snp array data: a scalable and automated data analysis pipeline 

  Artaza Alvarez, Haydee; Lavrichenko, Ksenia; Wolff, Anette Susanne Bøe; Røyrvik, Ellen Christine; Vaudel, Marc; Johansson, Stefan (Journal article; Peer reviewed, 2024)

  Background Rare copy number variants (CNVs) significantly influence the human genome and may contribute to disease susceptibility. High-throughput SNP genotyping platforms provide data that can be used for CNV detection, ...

• Use of Probiotics to Reduce Infections and Death and Prevent Colonization with Extended-spectrum beta-lactamase (ESBL) producing bacteria, among newborn infants in Haydom and surrounding area, Tanzania, a randomized controlled clinical trial 

  Langeland, Nina; Gidabayda, Joshua G; Blomberg, Bjørn; Löhr, Iren; Klingenberg, Claus; Kuwelker, Kanika; Mduma, Esto; Mdoe, Paschal (Report, 2021)

• An experimental study on intraoperative recovery of recurrent laryngeal nerve function 

  Setså, Erling Johan; Svendsen, Øyvind Sverre; Husby, Paul; Heimdal, John-Helge; Stangeland, Lodve; Dahle, Geir Olav; Brauckhoff, Katrin (Journal article; Peer reviewed, 2020)

  Objective If bilateral thyroid surgery is planned and staged thyroidectomy considered in case of loss of neuromonitoring signal (LOS), a waiting time of 20 minutes is suggested for evaluation of early nerve recovery. This ...

• Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism 

  Solé-Navais, Pol; Juodakis, Julius; Ytterberg, Karin; Wu, Xiaoping; Bradfield, Jonathan P.; Vaudel, Marc; LaBella, Abigail L.; Helgeland, Øyvind; Flatley, Christopher; Geller, Frank; Finel, Moshe; Zhao, Mengqi; Lazarus, Philip; Hakonarson, Hakon; Magnus, Per Minor; Andreassen, Ole A.; Njølstad, Pål Rasmus; Grant, Struan F. A.; Feenstra, Bjarke; Muglia, Louis J.; Johansson, Stefan; Zhang, Ge; Jacobsson, Bo (Journal article; Peer reviewed, 2024)

  Jaundice affects almost all neonates in their first days of life and is caused by the accumulation of bilirubin. Although the core biochemistry of bilirubin metabolism is well understood, it is not clear why some neonates ...

• Impact of the Graphene Production Methods Sonication and Microfluidization on In Vitro and In Vivo Toxicity, Macrophage Response, and Complement Activation 

  Førde, Jan-Lukas; Alhourani, Abdelnour; Carey, Tian; Arbab, Adrees; Fladmark, Kari Espolin; Skrede, Silje; Mollnes, Tom Eirik; Herfindal, Lars; Hagland, Hanne Røland (Journal article; Peer reviewed, 2024)

  Graphene, a material composed of a two-dimensional lattice of carbon atoms, has due to its many unique properties a wide array of potential applications in the biomedical field. One of the most common production methods ...

• Exposure to Per- and Polyfluoroalkyl Substances and Timing of Puberty in Norwegian Boys: Data from the Bergen Growth Study 2 

  Forthun, Ingvild Halsør; Roelants, Mathieu; Knutsen, Helle Katrine; Haug, Line Småstuen; Iszatt, Nina; Schell, Lawrence M.; Jugessur, Astanand; Bjerknes, Robert; Oehme, Ninnie Helen Bakken; Madsen, Andre Greger; Bruserud, Ingvild S.; Juliusson, Pétur Benedikt (Journal article; Peer reviewed, 2024)

  Per- and polyfluoroalkyl substances (PFAS) are widespread environmental contaminants with endocrine-disruptive properties. Their impact on puberty in boys is unclear. In this cross-sectional study, we investigated the ...

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