Faculty of Medicine: Recent submissions

Now showing items 1-20 of 5146

    • Genetic risk scores and hallucinations in patients with Parkinson disease 

      Kusters, Cynthia D.J.; Paul, Kimberly C.; Folle, Aline Duarte; Keener, Adrienne M.; Bronstein, Jeff M.; Dobricic, Valerija; Tysnes, Ole-Bjørn; Bertram, Lars; Alves, Guido Werner; Sinsheimer, Janet S.; Lill, Christina M.; Maple-Grødem, Jodi; Ritz, Beate R. (Journal article; Peer reviewed, 2020)
      Objective We examine the hypothesized overlap of genetic architecture for Alzheimer disease (AD), schizophrenia (SZ), and Parkinson disease (PD) through the use of polygenic risk scores (PRSs) with the occurrence of ...

    • Effects of oral nutrition supplements in persons with dementia: A systematic review 

      Tangvik, Randi Julie; Bruvik, Frøydis Kristine; Drageset, Jorunn; Kyte, Kristin; Hunskår, Irene (Journal article; Peer reviewed, 2021)
      Objective Persons with dementia are at risk of malnutrition, evidenced by low dietary intake, which has consequences for nutritional status, activity of daily living and disease progression. The effects of oral nutrition ...

    • The burden of household out-of-pocket health expenditures in Ethiopia: estimates from a nationally representative survey (2015–16) 

      Kiros, Mizan; Dessie, Ermias; Tolla, Mieraf Taddesse; Johansson, Kjell Arne; Norheim, Ole Frithjof; Memirie, Solomon Tessema; Verguet, Stéphane; Jbaily, Abdulrahman (Journal article; Peer reviewed, 2020)
      In Ethiopia, little is known about the extent of out-of-pocket health expenditures and the associated financial hardships at national and regional levels. We estimated the incidence of both catastrophic and impoverishing ...

    • NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet 

      Sokolova, Marina; Yang, Kuan; Hansen, Simen Hyll; Louwe, Mieke C.; Kummen, Martin; Hov, Johannes Espolin Roksund; Sjaastad, Ivar; Berge, Rolf Kristian; Halvorsen, Bente; Aukrust, Pål; Yndestad, Arne; Ranheim, Trine (Journal article; Peer reviewed, 2020)
      Obesity-related diseases (e.g. type 2 diabetes mellitus and cardiovascular disorders) represent an increasing health problem worldwide. NLRP3 inflammasome activation may underlie obesity-induced inflammation and insulin ...

    • Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women 

      Steinthorsdottir, Valgerdur; McGinnis, Ralph; Williams, Nicholas O.; Stefánsdóttir, Lilja; Thorleifsson, Gudmar; Shooter, Scott; Fadista, João; Sigurdsson, Jon K.; Auro, Kirsi; Berezina, Galina; Borges, Maria-Carolina; Bumpstead, Suzannah; Bybjerg-Grauholm, Jonas; Colgiu, Irina; Dolby, Vivien A.; Dudbridge, Frank; Engel, Stephanie M.; Franklin, Christopher S.; Frigge, Michael L; Frisbaek, Yr; Geirsson, Reynir T.; Geller, Frank; Gretarsdottir, Solveig; Gudbjartsson, Daniel F.; Harmon, Quaker; Hougaard, David Michael; Hegay, Tatyana; Helgadottir, Anna; Hjartardóttir, Sigrún; Jääskeläinen, Tiina; Johannsdottir, Hrefna; Jonsdottir, Ingileif; Juliusdottir, Thorhildur; Kalsheker, Noor; Kasimov, Abdumadjit; Kemp, John P.; Kivinen, Katja; Klungsøyr, Kari; Lee, Wai K; Melbye, Mads; Miedzybrodska, Zosia; Moffett, Ashley; Najmutdinova, Dilbar; Nishanova, Firuza; Olafsdottir, Thorunn; Perola, Markus; Pipkin, Fiona Broughton; Poston, Lucilla; Prescott, Gordon; Saevarsdottir, Saedis; Salimbayeva, Damilya; Scaife, Paula Juliet; Skotte, Line; Staines-Urias, Eleonora; Stefansson, Olafur A.; Sørensen, Karina Meden; Thomsen, Liv Cecilie Vestrheim; Tragante, Vinicius; Trogstad, Lill; Simpson, Nigel A.B.; Aripova, Tamara; Casas, Juan P; Dominiczak, Anna F; Walker, James J.; Thorsteinsdottir, Unnur; Iversen, Ann-Charlotte; Feenstra, Bjarke; Lawlor, Deborah A.; Boyd, Heather Allison; Magnus, Per; Laivuori, Hannele; Zakhidova, Nodira; Syvatova, Gulnara; Stefansson, Kari; Morgan, Linda (Journal article; Peer reviewed, 2020)
      Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate ...

    • Does photobiomodulation therapy combined to static magnetic field (PBMT-sMF) promote ergogenic effects even when the exercised muscle group is not irradiated? A randomized, triple-blind, placebo-controlled trial 

      Machado, Caroline Dos Santos Monteiro; Casalechi, Heliodora Leão; Vanin, Adriane Aver; De Azevedo, Jônatas Bezerra; de Carvalho, Paulo de Tarso Camillo; Leal, Ernesto Cesar Pinto Jr (Journal article; Peer reviewed, 2020)
      Background: The direct application of photobiomodulation therapy (PBMT) using low-level laser therapy (LLLT) and light emitting diodes (LEDs) combined with a static magnetic field (sMF) (PBMT-sMF) to target tissues is shown ...

    • Juridification of maternal deaths in Ethiopia: A study of the Maternal and Perinatal Death Surveillance and Response (MPDSR) system 

      Melberg, Andrea; Teklemariam, Lidiya; Moland, Karen Marie Ingeborg; Aasen, Henriette Sinding; Sisay, Mitike Molla (Journal article; Peer reviewed, 2020)
      Juridification of maternal health care is on the rise globally, but little is known about its manifestations in resource constrained settings in sub-Saharan Africa. The Maternal and Perinatal Death Surveillance and Response ...

    • Is cycle network expansion cost-effective? A health economic evaluation of cycling in Oslo 

      Lamu, Admassu Nadew; Jbaily, Abdulrahman; Verguet, Stéphane; Robberstad, Bjarne; Norheim, Ole Frithjof (Journal article; Peer reviewed, 2020)
      Background: Expansion of designated cycling networks increase cycling for transport that, in turn, increase physical activity, contributing to improvement in public health. This paper aims to determine whether cycle-network ...

    • Point Shear Wave Elastography and the Effect of Physical Exercise, Alcohol Consumption, and Respiration in Healthy Adults 

      Taraldsen, Victoria; Tomasgard, Sunneva; Rudlang, Margrethe Thune; Gilja, Odd Helge; Vesterhus, Mette; Mjelle, Anders Batman (Journal article; Peer reviewed, 2020)
      Purpose Ultrasound elastography is a noninvasive method for liver stiffness measurement (LSM) with the aim of reflecting approximate liver fibrosis load. Despite minimal evidence, current guidelines recommend 10 min of ...

    • Colorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial 

      Randel, Kristin Ranheim; Schult, Anna Lisa; Botteri, Edoardo; Hoff, Geir; Bretthauer, Michael; Ursin, Giske; Natvig, Erik; Berstad, Paula; Jørgensen, Anita; Sandvei, Per Kristian; Olsen, Marie Kristin Ek; Frigstad, Svein Oskar; Darre-Næss, Ole; Norvard, Espen R.; Bolstad, Nils; Kørner, Hartwig; Wibe, Arne; Wensaas, Knut-Arne; de Lange, Thomas; Holme, Øyvind (Journal article; Peer reviewed, 2021)
      Background and aims: The comparative effectiveness of sigmoidoscopy and fecal immunochemical testing (FIT) for colorectal cancer (CRC) screening is unknown. Methods: Individuals aged 50-74 years living in South-East Norway ...

    • Similar early mortality risk after cemented compared with cementless total hip arthroplasty for primary osteoarthritis: data from 188,606 surgeries in the Nordic Arthroplasty Register Association database 

      Pedersen, Alma B.; Mailhac, Aurélie; Garland, Anne; Overgaard, Søren; Furnes, Ove; Lie, Stein Atle; Fenstad, Anne Marie; Rogmark, Cecilia; Kärrholm, Johan; Rolfson, Ola; Haapakoski, Jaason; Eskelinen, Antti; Mäkelä, Keijo; Hailer, Nils P. (Journal article; Peer reviewed, 2021)
      Background and purpose — Current literature indicates no difference in 90-day mortality after cemented compared with cementless total hip arthroplasty (THA). However, previous studies are hampered by potential selection ...

    • Association between fixation type and revision risk in total knee arthroplasty patients aged 65 years and older: a cohort study of 265,877 patients from the Nordic Arthroplasty Register Association 2000–2016 

      Irmola, Tero; Ponkilainen, Ville; Mäkelä, Keijo; Robertsson, Otto; W-Dahl, Annette; Furnes, Ove; Fenstad, Anne Marie; Pedersen, Alma B.; Schrøder, Henrik M.; Eskelinen, Antti; Niemeläinen, Mika J (Journal article; Peer reviewed, 2021)
      Background and purpose — The population of the Nordic countries is aging and the number of elderly patients undergoing total knee arthroplasty (TKA) is also expected to increase. Reliable fixation methods are essential to ...

    • AXL is a driver of stemness in normal mammary gland and breast cancer 

      Engelsen, Agnete; Wnuk-Lipinska, Katarzyna; Bougnaud, Sébastien; Vatter, Fanny A. Pelissier; Tiron, Crina Elena; Villadsen, René; Miyano, Masaru; Lotsberg, Maria Lie; Madeleine, Noëlly; Panahandeh, Pouda; Dhakal, Sushil; Tan, Tuan Zea; Peters, Stacey D'Mello; Grøndal, Sturla Magnus; Aziz, Sura Mohammed; Nord, Silje; Herfindal, Lars; Stampfer, Martha R.; Sørlie, Therese; Brekken, Rolf A; Straume, Oddbjørn; Halberg, Nils; Gausdal, Gro; Thiery, Jean Paul; Akslen, Lars A.; Petersen, Ole W.; LaBarge, Mark A.; Lorens, James (Journal article; Peer reviewed, 2020)
      The receptor tyrosine kinase AXL is associated with epithelial plasticity in several solid tumors including breast cancer and AXL-targeting agents are currently in clinical trials. We hypothesized that AXL is a driver of ...

    • Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60° north latitude: A randomised trial 

      Bratlie, Marianne; Hagen, Ingrid Valheim; Helland, Anita; Midttun, Øivind; Ulvik, Arve; Rosenlund, Grethe; Sveier, Harald; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2020)
      Low serum concentrations of several vitamins have been linked to increased risk of diseases including insulin resistance and type 2 diabetes (T2D). Fish is a good source of several vitamins, and the prevalence of T2D is ...

    • Hemophagocytic lymphohistiocytosis and miliary tuberculosis in a previously healthy individual: a case report 

      Trovik, Linn; Sandnes, Miriam; Blomberg, Bjørn; Holmaas, Gunhild; Ahmed, Aymen B.; Tvedt, Tor Henrik Anderson; Vintermyr, Olav Karsten; Reikvam, Håkon (Journal article; Peer reviewed, 2020)
      Background Hemophagocytic lymphohistiocytosis (HLH) is a rare heterogenous genetic or acquired hyperinflammatory syndrome associated with a high degree of morbidity and mortality. HLH has clinical manifestations related ...

    • Cognitive behavior therapy for internalizing disorders in children and adolescents in routine clinical care: A systematic review and meta-analysis 

      Wergeland, Gro Janne; Riise, Eili Nygard; Öst, Lars Gøran (Journal article; Peer reviewed, 2020)
      Cognitive behavioral therapy (CBT) has received considerable empirical support for internalizing disorders including anxiety, depression, obsessive-compulsive disorder, and post-traumatic stress disorder in children and ...

    • Hormone references for ultrasound breast staging and endocrine profiling to detect female onset of puberty 

      Madsen, Andre; Bruserud, Ingvild Særvold; Bertelsen, Bjørn-Erik; Roelants, Mathieu; Oehme, Ninnie; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Petur Benedikt (Journal article; Peer reviewed, 2020)
      Context Application of ultrasound (US) to evaluate attainment and morphology of glandular tissue provides a new rationale for evaluating onset and progression of female puberty, but currently no hormone references complement ...

    • How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa) 

      Cheesman, Rosa; Eilertsen, Espen Moen; Ahmadzadeh, Yasmin I.; Gjerde, Line C.; Hannigan, Laurie John; Havdahl, Alexandra; Young, Alexander I.; Eley, Thalia C.; Njølstad, Pål Rasmus; Magnus, Per; Andreassen, Ole Andreas; Ystrøm, Eivind; McAdams, Tom A. (Journal article; Peer reviewed, 2020)
      Background Many studies detect associations between parent behaviour and child symptoms of anxiety and depression. Despite knowledge that anxiety and depression are influenced by a complex interplay of genetic and ...

    • Maintained survival outcome after reducing lymphadenectomy rates and optimizing adjuvant treatment in endometrial cancer 

      Forsse, David Erik; Berg, Hege Fredriksen; Bozickovic, Olivera; Engerud, Hilde Renate; Halle, Mari Kyllesø; Høivik, Erling Andre; Woie, Kathrine; Werner, Henrica Maria Johanna; Haldorsen, Ingfrid S.; Trovik, Jone; Krakstad, Camilla (Journal article; Peer reviewed, 2020)
      Objective Main controversies in endometrial cancer treatment include the role of lymphadenectomy and optimal adjuvant treatment. We assessed clinical outcome in a population-based endometrial cancer cohort in relation to ...

    • Comparison of 6-week PMTCT outcomes for HIV-exposed and HIV-unexposed infants in the era of lifelong ART: Results from an observational prospective cohort study 

      Tiam, Appolinaire; Kassaye, Seble G.; Machekano, Rhoderick; Tukei, Vincent; Gill, Michelle M.; Mokone, Majoalane; Letsie, Mosilinyane; Tsietso, Mots'Oane; Seipati, Irene; Barasa, Janety; Isavwa, Anthony; Tylleskär, Thorkild; Guay, Laura (Journal article; Peer reviewed, 2019)
      Background Lifelong antiretroviral therapy (ART) reduces mother-to-child HIV transmission (MTCT) and improves maternal health. Data on the outcomes of HIV-exposed infants (HEI) compared to their unexposed counterparts in ...