Browsing Faculty of Medicine by Title

Now showing items 1-20 of 5865

    • 0729. Interstitial changes in spleen during sepsis 

      Svendsen, Øyvind Sverre; Stangeland, Lodve; Elvevoll, Bjørg; Gjertsen, Bjørn Tore; Skavland, Jørn; Wiig, Helge; Tenstad, Olav; Husby, Paul (Conference object; Peer reviewed, 2014-09-26)

    • The 14-3-3 proteins in regulation of cellular metabolism 

      Kleppe, Rune; Martinez, Aurora; Døskeland, Stein Ove; Haavik, Jan (Peer reviewed; Journal article, 2011-09)
      Thirty years ago, it was discovered that 14-3-3 proteins could activate enzymes involved in amino acid metabolism. In the following decades, 14-3-3s have been shown to be involved in many different signaling pathways that ...

    • 18-24-month HIV-free survival as measurement of the effectiveness of prevention of mother-to-child transmission in the context of lifelong antiretroviral therapy: Results of a community-based survey 

      Tiam, Appolinaire; Gill, Michelle; Machekano, Rhoderick; Tukei, Vincent; Mokone, Majoalane; Viana, Shannon; Letsie, Mosilinyane; Tsietso, Mots'Oane; Seipati, Irene; Khachane, Cecilia; Nei, Marethabile; Mohai, Florence; Tylleskär, Thorkild; Guay, Laura (Journal article; Peer reviewed, 2020)
      Introduction Population-based HIV-free survival at 18–24 months of age among HIV-exposed infants in high prevalence settings in the era of treatment for all is largely unknown. We conducted a community-based survey to ...

    • An 18-Gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer 

      Mannelqvist, Monica; Wik, Elisabeth; Stefansson, Ingunn; Akslen, Lars A. (Peer reviewed; Journal article, 2014-06-06)
      Aims: Vascular invasion by tumor cells is known to be important for cancer progression. By microarray and qPCR analyses, we earlier identified an 18-gene signature associated with vascular involvement in endometrial cancer. ...

    • 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans 

      Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi; Ellegaard, Maria; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Bøen, Rune; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Ching, Christopher R. K.; Cichon, Sven; Ciufolini, Simone; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dale, Anders M.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J. C.; Zubicaray, Greig I. de; Zwarte, Sonja M. C. de; Desrivieres, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fejgin, Kim; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Haberg, Asta Kristine; Hall, Jeremy; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek P.; Hillegers, Manon H. J.; Hoffmann, Per; Holleran, Laurena; Holmes, Avram J.; Johansson, Stefan; Jönsson, Erik Gunnar; Hellard, Stephanie Francoise Claire Le; Lundervold, Arvid; Lundervold, Astri J.; Moberget, Torgeir; Nordvik, Jan Egil; Sando, Sigrid Botne; Steen, Vidar Martin; Tamnes, Christian Krog; Agartz, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole; Homuth, Georg; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Ikeda, Masashi; Jahanshad, Neda; Jockwitz, Christiane; Jørgensen, Niklas R.; Kikuchi, Masataka; Knowles, Emma E. M.; Kumar, Kuldeep; Leu, Costin; Linden, David E. J.; Liu, Jingyu; Maillard, Anne M.; Martin, Nicholas G.; Martin-Brevet, Sandra; Mather, Karen A.; Mathias, Samuel R.; McMahon, Katie L.; McRae, Allan F.; Medland, Sarah E.; Meyer-Lindenberg, Andreas; Modenato, Claudia; Monereo Sánchez, Jennifer; Morris, Derek W.; Mühleisen, Thomas W.; Murray, Robin M.; Nielsen, Jacob; Nyberg, Lars; Olde Loohuis, Loes M.; Ophoff, Roel A.; Owen, Michael J.; Paus, Tomas; Pausova, Zdenka; Peralta, Juan M.; Pike, G. Bruce; Prieto, Carlos; Quinlan, Erin B.; Reinbold, Céline S.; Reis Marques, Tiago; Rucker, James J. H.; Sachdev, Perminder S.; Schofield, Peter R.; Schork, Andrew J.; Schumann, Gunter; Shin, Jean; Shumskaya, Elena; Silva, Ana I.; Sisodiya, Sanjay M.; Stein, Dan J.; Strike, Lachlan T.; Suzuki, Ikuo K.; Teumer, Alexander; Thalamuthu, Anbupalam; Tordesillas-Gutiérrez, Diana; Uhlmann, Anne; Ulfarsson, Magnus O.; van ‘t Ent, Dennis; van den Bree, Marianne B. M.; Vanderhaeghen, Pierre; Vassos, Evangelos; Wen, Wei; Wittfeld, Katharina; Wright, Margaret J.; Stefansson, Hreinn; Stefansson, Kari; Jacquemont, Sébastien; Thompson, Paul M. (Journal article; Peer reviewed, 2021)
      Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...

    • 2.5-fold increased risk of recurrent acute myocardial infarction with familial hypercholesterolemia 

      Svendsen, Karianne; Krogh, Henriette Walaas; Igland, Jannicke; Tell, Grethe S.; Mundal, Liv J.; Holven, Kirsten Bjørklund; Bogsrud, Martin P.; Leren, Trond P.; Retterstøl, Kjetil (Journal article; Peer reviewed, 2021)
      Background and aims A first-time acute myocardial infarction (AMI) is a severe diagnosis that leads to initiation or intensification of lipid-lowering medication to prevent recurrent events. Individuals with familial ...

    • The 2009 influenza pandemic in primary care. Clinical manifestations, attitudes and utilisation of services 

      Simonsen, Kristian Anton (Doctoral thesis, 2015-03-25)
      Background: Primary care plays a major role in the response to a pandemic. The objectives of this thesis were to investigate the outbreak of the 2009 influenza pandemic from a primary care perspective with focus on clinical ...

    • 24-Month HIV-free survival among HIV-exposed Infants in Lesotho: the PEAWIL cohort study 

      Tukei, Vincent; Machekano, Rhoderick; Gill, Michelle; Tiam, Appolinaire; Mokone, Majoalane; Isavwa, Anthony; Nyabela, Malijane; Mots’oane, Tsietso; Nchephe, Seipati; Letsie, Mosilinyane; Kassaye, Seble G.; Guay, Laura (Journal article; Peer reviewed, 2020)
      Introduction Following the implementation of the provision of lifelong antiretroviral therapy to all HIV-positive pregnant or breastfeeding women for prevention of mother-to-child transmission (PMTCT) of HIV by the Kingdom ...

    • 25-hydroxy-vitamin D concentration is not affected by severe or non-severe pneumonia, or inflammation, in young children 

      Haugen, Johanne; Chandyo, Ram Krishna; Ulak, Manjeswori; Mathisen, Maria; Basnet, Sudha; Brokstad, Karl Albert; Valentiner-Branth, Palle; Shrestha, Prakash S.; Strand, Tor A (Peer reviewed; Journal article, 2017-01-17)
      Poor vitamin D status has been associated with increased risk and severity of respiratory tract infections. Whether or not inflammation and infection affects 25-hydroxy vitamin D (25(OH)D) concentration is controversial ...

    • 2D and 3D U-Nets for skull stripping in a large and heterogeneous set of head MRI using fastai 

      Kaliyugarasan, Satheshkumar; Kocinski, Marek; Lundervold, Arvid; Lundervold, Alexander Selvikvåg (Journal article, 2020)
      Skull stripping in brain imaging is the removal of the parts of images corresponding to non-brain tissue. Fast and accurate skull stripping is a crucial step for numerous medical brain imaging applications, e.g. registration, ...

    • A 3-D post-mortem model provides rationale for complications in gastrointestinal surgery : a post-mortem corrosion-cast model 

      Ignjatovic, Dejan (Doctoral thesis, 2007-06-08)

    • A 4 year prospective longitudinal study of progression of dental erosion associated to lifestyle in 13-14 year-old Swedish adolescents 

      Hasselkvist, Agneta; Johansson, Anders; Johansson, Ann-Katrin Gerd (Peer reviewed; Journal article, 2016-04)
      Objectives To evaluate the progression of dental erosion in 13–14 year-olds after 4 years, and its association with lifestyle and oral health. Methods 227 randomly selected 13–14 year-olds from a Public Dental Clinic, ...

    • 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy 

      Joubert, Bonnie R.; Håberg, Siri Eldevik; Nilsen, Roy Miodini; Wang, Xuting; Vollset, Stein Emil; Murphy, Susan K; Huang, Zhiqing; Hoyo, Cathrine; Midttun, Øivind; Cupul-Uicab, Lea A; Ueland, Per Magne; Wu, Michael C; Nystad, Wenche; Bell, Douglas A; Peddada, Shyamal D; London, Stephanie J (Peer reviewed; Journal article, 2012-10)
      Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple ...

    • A 60-year follow-up of the incidence and prevalence of multiple sclerosis in Hordaland County, Western Norway 

      Grytten, Nina; Aarseth, Jan Harald; Lunde, Hanne Marie; Myhr, Kjell-Morten (Peer reviewed; Journal article, 2015-01-14)
      Objective: Investigate the incidence of multiple sclerosis during 1953–2013 and estimate the prevalence rate of MS on 1 January 2003 and 2013 in Hordaland County, Western Norway. Methods: All patients with onset of disease ...

    • Ability in daily activities after early supported discharge models of stroke rehabilitation 

      Taule, Tina; Strand, Liv Inger; Assmus, Jörg; Skouen, Jan Sture (Peer reviewed; Journal article, 2015)
      More knowledge is needed about how different rehabilitation models in the municipality influence stroke survivors’ ability in activities of daily living (ADL). Objectives: To compare three models of outpatient rehabilitation; ...

    • Ability of a lean-seafood diet to modulate lipid and glucose metabolism in healthy humans – a randomized controlled trial with a crossover design 

      Aadland, Eli Kristin (Doctoral thesis, 2016-01-08)
      Background: A Westernised lifestyle, which involves a high-energy diet and reduced physical activity, is indisputably linked to the pandemics of obesity and type 2 diabetes. Prevention of cardiovascular disease and type 2 ...

    • Abnormal Uroguanylin Immunoreactive Cells Density in the Duodenum of Patients with Diarrhea-Predominant Irritable Bowel Syndrome Changes following Fecal Microbiota Transplantation 

      Mazzawi, Tarek; Eikrem, Øystein Solberg; Lied, Gülen Arslan; Hausken, Trygve (Journal article; Peer reviewed, 2020)
      Altered densities of enteroendocrine cells play an important role in patients with irritable bowel syndrome (IBS). Uroguanylin activates guanylate cyclase-C to regulate intestinal electrolyte and water transport. Aim. To ...

    • Abrogation of Anthracycline and Ischemia-Reperfusion Induced Injury by Cell Signaling Modulators 

      Wergeland, Anita (Doctoral thesis; Peer reviewed, 2013-10-18)
      Chemotherapy has a long history in cancer treatment, and the anthracycline used in Paper I and II are among the most effective anti-cancer drugs developed. Unfortunately, the use of anthracyclines is dose-restricted due ...

    • Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice 

      Svärd, Jessica; Røst, Therese Halvorsen; Sommervoll, Camilla Elise Nergård; Haugen, Christine; Gudbrandsen, Oddrun Anita; Christensen, Anne Elisabeth; Rødahl, Eyvind; Fernø, Johan; Dankel, Simon N; Sagen, Jørn V.; Mellgren, Gunnar (Peer reviewed; Journal article, 2019)
      Studies have implicated the extracellular matrix (ECM) of adipose tissue in insulin resistance. The proteoglycan decorin, a component of ECM, has been associated with glucose tolerance, but possible causal effects on ...

    • Abundance and dynamics of anopheline larvae in a highland malarious area of south-central Ethiopia 

      Gebre-Michael, Teshome; Balkew, Meshesha; Lindtjørn, Bernt; Ayele, Abebe Animut (Peer reviewed; Journal article, 2012-06-13)
      Background: Malaria is a public health problem in Ethiopia, and increasingly so in highland areas, possibly because of global warming. This study describes the distribution, breeding habitat and monthly dynamics of anopheline ...