Browsing Faculty of Medicine by Title

Now showing items 2608-2627 of 4777

    • Label-free impedance flow cytometry for nanotoxicity screening 

      Ostermann, Melanie; Sauter, Alexander; Xue, Ying; Birkeland, Eivind Salmorin; Schoelermann, Julia; Holst, Bodil; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2020)
      The development of reliable and cost-efficient methods to assess the toxicity of nanomaterials (NMs) is critical for the proper identification of their impact on human health and for ensuring a safe progress of nanotechnology. ...

    • Label-free monitoring of uptake and toxicity of endoprosthetic wear particles in human cell cultures 

      Jonitz-Heincke, Anika; Tillmann, Jenny; Ostermann, Melanie; Springer, Armin; Bader, Rainer; Høl, Paul Johan; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2018)
      The evaluation of the biological effects of endoprosthetic wear particles on cells in vitro relies on a variety of test assays. However, most of these methods are susceptible to particle-induced interferences; therefore, ...

    • Laboratory contamination in airway microbiome studies 

      Drengenes, Christine; Wiker, Harald G; Kalananthan, Tharmini; Nordeide, Eli; Eagan, Tomas Mikal; Nielsen, Rune (Peer reviewed; Journal article, 2019-08-14)
      Background The low bacterial load in samples acquired from the lungs, have made studies on the airway microbiome vulnerable to contamination from bacterial DNA introduced during sampling and laboratory processing. We have ...

    • Laboratory tests in out-of-hours services in Norway. Studies with special emphasis on use and consequences of C-reactive protein test in children 

      Rebnord, Ingrid Keilegavlen (Doctoral thesis, 2017-05-31)
      Background: Children with infections and respiratory symptoms have the highest contact rate with Norwegian out-of-hours (OOH) services, especially in the youngest age group, and during the winter season. Many contacts are ...

    • Labour onset and early labour. An exploration of first-time mothers’ and midwives’ experiences 

      Eri, Tine Schauer (Doctoral thesis, 2011-10-28)
      This dissertation is about how women experience waiting for the onset of labour, and how first-time mothers and midwives communicate during the early phases of labour. Most women in Norway give birth in public hospitals, ...

    • Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma 

      Obad, Nina; Espedal, Heidi; Jirík, Radovan; Sakariassen, Per Øystein; Rygh, Cecilie Brekke; Lund-Johansen, Morten; Taxt, Torfinn; Niclou, Simone Pierrette; Bjerkvig, Rolf; Keunen, Olivier (Peer reviewed; Journal article, 2017)
      Neo-angiogenesis represents an important factor for the delivery of oxygen and nutrients to a growing tumour, and is considered to be one of the main pathodiagnostic features of glioblastomas (GBM). Anti-angiogenic therapy ...

    • The laminin response in inflammatory bowel disease: Protection or malignancy? 

      Spenle, Caroline; Lefebvre, Olivier; Lacroute, Joel; Mechine-Neuville, Agnes; Barreau, Frederick; Blottiere, Herve M; Duclos, Bernard; Arnold, Christiane; Hussenet, Thomas; Hemmerle, Joseph; Gullberg, Donald; Kedinger, Michele; Sorokin, Lydia; Orend, Gertraud; Simon-Assmann, Patricia (Peer reviewed; Journal article, 2014-10-27)
      Laminins (LM), basement membrane molecules and mediators of epithelial-stromal communication, are crucial in tissue homeostasis. Inflammatory Bowel Diseases (IBD) are multifactorial pathologies where the microenvironment ...

    • Langtidsoppfølging av pasienter med Oral Lichen Planus - en retrospektiv studie 

      Strann, Linn Oppedal; Klyve, Rachel Fleten (Master thesis, 2010-02-01)
      The aim of this study was to evaluate progression of clinical appearance and symptoms in patients diagnosed with oral lichen planus (OLP), and observe if any malign transformation occurred. The study was retrospective and ...

    • Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in utero – the Norwegian Mother and Child Cohort Study 

      Husebye, Elisabeth Synnøve Nilsen; Gilhus, Nils Erik; Spigset, Olav; Daltveit, Anne Kjersti; Bjørk, Marte-Helene (Peer reviewed; Journal article, 2020)
      Background and purpose: The purpose was to examine the consequences of antiepileptic drug (AED) exposure during pregnancy on language abilities in children aged 5 and 8 years of mothers with epilepsy. Methods: The study ...

    • A large community outbreak of waterborne giardiasis- delayed detection in a non-endemic urban area 

      Nygård, Karin; Schimmer, Barbara; Søbstad, Øystein; Walde, Anna; Tveit, Ingvar; Langeland, Nina; Hausken, Trygve; Aavitsland, Preben (BMC Public Health 6(141), Peer reviewed; Journal article, 2006-05-25)
      Background: Giardia is not endemic in Norway, and more than 90% of reported cases acquire the infection abroad. In late October 2004, an increase in laboratory confirmed cases of giardiasis was reported in the city of ...

    • Large-scale external validation and comparison of prognostic models: An application to chronic obstructive pulmonary disease 

      Guerra, Beniamino; Haile, Sarah R.; Lamprecht, Bernd; Ramírez, Ana S.; Martinez-Camblor, Pablo; Kaiser, Bernhard; Alfageme, Inmaculada; Almagro, Pere; Casanova, Ciro; Esteban-González, Cristóbal; Soler-Cataluña, Juan J.; de-Torres, Juan P.; Miravitlles, Marc; Celli, Bartolomé R.; Marin, Jose M.; ter Riet, Gerben; Sobradillo, Patricia; Lange, Peter; Garcia-Aymerich, Judith; Antó, Jósep Maria; Turner, Alice M.; Han, Meilan K.; Langhammer, Arnulf; Leivseth, Linda; Bakke, Per S.; Johannessen, Ane; Oga, Toru; Cosio, Borja; Ancochea-Bermúdez, Julio; Echazarreta, Andrés; Roche, Nicolas; Burgel, Pierre-Régis; Sin, Don D.; Soriano, Joan B.; Puhan, Milo A. (Peer reviewed; Journal article, 2018-03-02)
      Background: External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive pulmonary disease ...

    • Large-scale genomics unveil polygenic architecture of human cortical surface area 

      Chen, Chi-Hua; Peng, Qian; Schork, Andrew J.; Lo, Min-Tzu; Fan, Chun-Chieh; Wang, Yunpeng; Desikan, Rahul S.; Bettella, Franscesco; Hagler, Donald J.; Westlye, Lars Tjelta; Kremen, William S.; Jernigan, Terry L.; Le Hellard, Stephanie; Steen, Vidar Martin; Espeseth, Thomas; Huentelman, Matt; Håberg, Asta; Agartz, Ingrid; Djurovic, Srdjan; Andreassen, Ole Andreas; Schork, Nicholas; Dale, Anders (Peer reviewed; Journal article, 2015-07-20)
      Little is known about how genetic variation contributes to neuroanatomical variability, and whether particular genomic regions comprising genes or evolutionarily conserved elements are enriched for effects that influence ...

    • Large-scale resting state network correlates of cognitive impairment in Parkinson’s disease and related dopaminergic deficits 

      Lebedev, Alexander; Westman, Eric; Simmons, Andrew; Lebedeva, Aleksandra; Siepel, Françoise J.; Pereira, Joana B.; Aarsland, Dag (Peer reviewed; Journal article, 2014-04-03)
      Cognitive impairment is a common non-motor feature of Parkinson’s disease (PD). Understanding the neural mechanisms of this deficit is crucial for the development of efficient methods for treatment monitoring and augmentation ...

    • Laryngeal response patterns during mechanically assisted cough in Amyotrophic Lateral Sclerosis 

      Andersen, Tiina Maarit (Doctoral thesis, 2018-06-21)
      Background: Patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical cough assist devices using the technique of mechanical insufflationexsufflation (MI-E) in order to improve cough and enhance clearance ...

    • Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis 

      Andersen, Tiina Maarit; Sandnes, Astrid; Brekka, Anne Kristine; Hilland, Magnus; Clemm, Hege; Fondenes, Ove; Tysnes, Ole Bjørn; Heimdal, John-Helge; Halvorsen, Thomas; Vollsæter, Maria; Røksund, Ola Drange (Peer reviewed; Journal article, 2017)
      Background: Most patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical insufflation–exsufflation (MI-E) in order to improve cough. This method often fails in ALS with bulbar involvement, allegedly ...

    • Laryngeal tube use in out-of-hospital cardiac arrest by paramedics in Norway 

      Sunde, Geir Arne; Brattebø, Guttorm; Ødegården, Terje; Kjernlie, Dag Frode; Rødne, Emma Sjøgren; Heltne, Jon-Kenneth (Peer reviewed; Journal article, 2012-12-18)
      Background: Although there are numerous supraglottic airway alternatives to endotracheal intubation, it remains unclear which airway technique is optimal for use in prehospital cardiac arrests. We evaluated the use of the ...

    • Larynx during exercise: the unexplored bottleneck of the airways 

      Røksund, Ola Drange; Heimdal, John-Helge; Olofsson, Jan; Maat, Robert; Halvorsen, Thomas (Peer reviewed; Journal article, 2014-07-18)
      Exercise-induced shortness of breath is not uncommon in otherwise healthy young people. Based on the presenting symptoms alone, it is challenging to distinguish exercise-induced asthma (EIA) from exercise-induced obstruction ...

    • Larynx in exercising humans. The unexplored bottleneck of the airways 

      Røksund, Ola Drange (Doctoral thesis; Peer reviewed, 2012-06-21)

    • Laserbehandling av infeksjoner ved dentale implantater 

      Alstad, Miriam Elisabeth; Angelsen, Stine Victoria (Master thesis, 2009-04-27)
      En gjennomgang av litteraturen indikerer at peri- implantatrelaterte sykdommer oppstår svært ofte etter implantatforankret protetikk. Det er derfor viktig at det utarbeides forslag til behandlingsprotokoller og utprøves ...

    • Laserbehandling av infiserte tannkjøttslommer 

      Espervik, Annika; Eriksen, Elisabeth Schilbred (Master thesis, 2009-04-27)
      De fleste pasienter med kronisk marginal periodontitt responderer godt på tradisjonell periodontal behandling, men ca. 10 % ser ut til å ha en bakterieflora som er særlig behandlingsresistent. For disse pasientene er ...