Browsing Faculty of Medicine by Title
Now showing items 9373-9392 of 9415
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X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study
(Journal article; Peer reviewed, 2023)Background The association between genetic variants on the X chromosome to risk of COPD has not been fully explored. We hypothesize that the X chromosome harbors variants important in determining risk of COPD related ... -
The X-factor in ART: does the use of assisted reproductive technologies influence DNA methylation on the X chromosome?
(Journal article; Peer reviewed, 2023)Background Assisted reproductive technologies (ART) may perturb DNA methylation (DNAm) in early embryonic development. Although a handful of epigenome-wide association studies of ART have been published, none have investigated ... -
X-Linked Genes and Risk of Orofacial Clefts: Evidence from Two Population-Based Studies in Scandinavia
(Peer reviewed; Journal article, 2012-06-19)Background: Orofacial clefts are common birth defects of complex etiology, with an excess of males among babies with cleft lip and palate, and an excess of females among those with cleft palate only. Although genes on the ... -
X-ray microanalytical studies of initial mineralization in induced heterotopic bone formation in guinea pigs
(Journal article, 1981)Allogenic demineralized dentin implanted in the abdominal wall of guinea pigs induced heterotopic osteoid and bone formation. Samples of this tissue were frozen at -140° C, freeze-dried at -80° C, infiltrated with Spurr® ... -
XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase
(Journal article; Peer reviewed, 2021)Replication-associated single-ended DNA double-strand breaks (seDSBs) are repaired predominantly through RAD51-mediated homologous recombination (HR). Removal of the non-homologous end-joining (NHEJ) factor Ku from resected ... -
Xeno-free 3D Culture of Mesenchymal Stromal Cells For Bone Tissue Engineering
(Doctoral thesis, 2020)Clinical translation of innovative regenerative approaches using mesenchymal stromal cells (MSCs) is urgently needed for the treatment of challenging bone defects. The overall aim of this thesis, comprising of one systematic ... -
Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues
(Journal article; Peer reviewed, 2023)Background Induced pluripotent stem cells (iPS) can be generated from various somatic cells and can subsequently be differentiated to multiple cell types of the body. This makes them highly promising for cellular therapy ... -
Xeno-free spheroids of human gingiva-derived progenitor cells for bone tissue engineering
(Journal article; Peer reviewed, 2020)Gingiva has been identified as a minimally invasive source of multipotent progenitor cells (GPCs) for use in bone tissue engineering (BTE). To facilitate clinical translation, it is important to characterize GPCs in xeno-free ... -
Xerostomia in 75–85-year-olds: A longitudinal population study
(Journal article; Peer reviewed, 2023)Background: Xerostomia can pose significant problems for many elderly people. Objectives: To investigate longitudinal changes in prevalence, persistence, progression, remission and incidence of xerostomia from age 75 ... -
Xpert MTB/RIF assay can be used on archived gastric aspirate and induced sputum samples for sensitive diagnosis of paediatric tuberculosis
(Peer reviewed; Journal article, 2015-09-29)Background: Tuberculosis (TB) in children is neglected, mainly due to lack of sensitive diagnostic tools. Recently Xpert MTB/RIF assay has revolutionized the diagnostic field, but its usefulness in pediatric TB has not ... -
Xpert MTB/RIF ultra for rapid diagnosis of extrapulmonary tuberculosis in a high‑income low‑tuberculosis prevalence setting
(Journal article; Peer reviewed, 2020)The diagnosis of extrapulmonary tuberculosis (EPTB) is often challenging due to paucibacillary nature of the disease. Xpert MTB/RIF Ultra (Ultra) has been developed to improve detection of Mycobacterium tuberculosis complex ... -
A year of contemplation: looking back and moving forward
(Peer reviewed; Journal article, 2009-07-13) -
Young adults with depression: A registry-based longitudinal study of work-life marginalisation. The Norwegian GP-DEP study
(Journal article; Peer reviewed, 2023)Aims: To explore the association between a depression diagnosis in young adulthood and risk of marginalisation at age 29 years, among those who had completed upper secondary school and those who had not completed at age ... -
Young ischaemic stroke incidence and demographic characteristics - The Norwegian stroke in the young study - A three-generation research program
(Journal article; Peer reviewed, 2019)Introduction: Norwegian Stroke in the Young Study (NOR-SYS) is a three-generation research program of young ischaemic stroke. In this study, we assessed ischaemic stroke incidence, education and work status among young ... -
Young people with epilepsy have an increased risk of eating disorder and poor quality diet
(Peer reviewed; Journal article, 2018-03)Objective: To investigate whether adolescents with epilepsy are at increased risk of having self‐reported eating disorder symptoms and poor quality diet compared to young people from the general population. Methods: We ... -
“Your heart keeps bleeding”: lived experiences of parents with a perinatal death in Northern Uganda
(Journal article; Peer reviewed, 2022-06-15)Background: Worldwide, two million babies are stillborn and 1.8 million babies die before completing seven days of life. Approximately 4% of pregnant women in Uganda experience perinatal death. The response following a ... -
Yrkeseksponering for elektromagnetiske felt blant radiografer ved bruk av magnetisk resonans
(Master thesis, 2018-06-22)In July 2016, the EU Electromagnetic Field Directive (Direktiv2013/35/EU, 2013) entered into force. Previous studies have shown that the action and limit values in the Directive can not be met when working with magnetic ... -
Zambian newborns exposed to HIV and antiretroviral drugs: Evolution of neutrophil cell count in the first 6 months. Sub-study of the ANRS 12174 trial in Zambia
(Master thesis, 2012-09-24)Background: The efficacy of antiretroviral drugs (ARVs) for the prevention of HIV transmission from mother to child is one of the greatest successes of antiretroviral therapy. However, concern has been expressed in several ... -
The Zebrafish Larva as a Model System for Myeloid Malignancies
(Doctoral thesis, 2024-02-23)Myeloid kreft er ein ukontrollert deling av dei myeloide stamcellene som finst i beinmergen. Døme på myeloid kreft er akutt myeloid leukemi (AML) og myelodysplastisk syndrom. Desse kreftformane er vanlegast hjå eldre ... -
Zebrafish Larvae as a Model Organism to Study Biotransformation
(Master thesis, 2023-05-22)The zebrafish larva is an increasingly used model organism in many fields of research, including drug development. Due to traits like their small size, rapid development, and high degree of genetic similarity with humans, ...