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  • Wavelet Screening identifies regions highly enriched for differentially methylated loci for orofacial clefts 

    Denault, William Robert Paul; Romanowska, Julia; Haaland, Øystein Ariansen; Lyle, Robert; Taylor, Jack A.; Xu, Zongli; Lie, Rolv T.; Gjessing, Håkon K.; Jugessur, Astanand (Journal article; Peer reviewed, 2021)
    DNA methylation is the most widely studied epigenetic mark in humans and plays an essential role in normal biological processes as well as in disease development. More focus has recently been placed on understanding ...
  • Effects of nuisance submerged vegetation on the fauna in Norwegian rivers 

    Velle, Gaute; Skoglund, Helge; Barlaup, Bjørn Torgeir (Journal article; Peer reviewed, 2021)
    The abundance of aquatic vegetation is increasing in rivers and lakes worldwide. The aim of this study was to find how the macrophyte Juncus bulbosus Linnaeus affects salmonids and benthic macroinvertebrates in Norwegian ...
  • Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors 

    Torgersen, Kristin Stensland; Bahrami, Shahram; Frei, Oleksandr; Shadrin, Alexey; O'Connell, Kevin Sean; Smeland, Olav Bjerkehagen; Munkhaugen, John; Djurovic, Srdjan; Dammen, Toril; Andreassen, Ole A. (Journal article; Peer reviewed, 2021)
    Neuroticism is associated with poor health, cardiovascular disease (CVD) risk factors and coronary artery disease (CAD). The conditional/conjunctional false discovery rate method (cond/conjFDR) was applied to genome wide ...
  • Calibration and assessment of electrochemical low-cost sensors in remote alpine harsh environments 

    Dallo, Frederico; Zannoni, Daniele; Gabrieli, Jacopo; Cristofanelli, Paolo; Calzolari, Francescopiero; de Blasi, Fabrizio; Spolaor, Andrea; Battistel, Dario; Lodi, Rachele; Cairns, Warren R. L.; Fjæraa, Ann Mari; Bonasoni, Paolo; Barbante, Carlo (Journal article; Peer reviewed, 2021)
    This work presents results from an original open-source low-cost sensor (LCS) system developed to measure tropospheric O3 in a remote high altitude alpine site. Our study was conducted at the Col Margherita Observatory ...
  • Characterization of the atmospheric environment during extreme precipitation events associated with atmospheric rivers in Norway - Seasonal and regional aspects 

    Michel, Clio; Sorteberg, Asgeir; Eckhardt, Sabine; Weijenborg, Christian; Stohl, Andreas; Cassiani, Massimo (Journal article; Peer reviewed, 2021)
    Extreme precipitation events in Norway in all seasons are often linked to atmospheric rivers (AR). We show that during the period 1979–2018 78.5% of the daily extreme precipitation events in Southwestern Norway are linked ...
  • Population dynamic regulators in an empirical predator-prey system 

    Frank, Anna-Simone Josefine; Subbey, S.; Kobras, Melanie; Gjøsæter, H. (Journal article; Peer reviewed, 2021)
    Capelin (Mallotus villosus) is a short-lived (1–4 years) fish species, that plays a crucial role by dominating the intermediate trophic level in the Barents Sea. Several episodes of extreme biomass decline (collapse) have ...
  • Preference-based instrumental variables in health research rely on important and underreported assumptions: a systematic review 

    Widding-Havneraas, Tarjei; Chaulagain, Ashmita; Lyhmann, Ingvild; Zachrisson, Henrik Daae; Elwert, Felix; Markussen, Simen; McDaid, David; Mykletun, Arnstein (Journal article; Peer reviewed, 2021)
    Objective: Preference-based instrumental variables (PP IV) designs can identify causal effects when patients receive treatment due to variation in providers’ treatment preference. We offer a systematic review and methodological ...
  • The salmon louse genome: Copepod features and parasitic adaptations 

    Skern-Mauritzen, Rasmus; Malde, Ketil; Eichner, Christiane; Dondrup, Michael; Furmanek, Tomasz; Besnier, Francois; Komisarczuk, Anna Zofia; Nuhn, Michael; Dalvin, Sussie; Edvardsen, Rolf Brudvik; Klages, Sven; Huettel, Bruno; Stueber, Kurt; Grotmol, Sindre; Karlsbakk, Egil Erlingsson; Kersey, Paul; Leong, Jong S; Glover, Kevin Alan; Reinhardt, Richard; Lien, Sigbjørn; Jonassen, Inge; Koop, Ben F; Nilsen, Frank (Journal article; Peer reviewed, 2021)
    Copepods encompass numerous ecological roles including parasites, detrivores and phytoplankton grazers. Nonetheless, copepod genome assemblies remain scarce. Lepeophtheirus salmonis is an economically and ecologically ...
  • 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans 

    Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi; Ellegaard, Maria; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Bøen, Rune; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Ching, Christopher R. K.; Cichon, Sven; Ciufolini, Simone; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dale, Anders M.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J. C.; Zubicaray, Greig I. de; Zwarte, Sonja M. C. de; Desrivieres, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fejgin, Kim; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Haberg, Asta Kristine; Hall, Jeremy; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek P.; Hillegers, Manon H. J.; Hoffmann, Per; Holleran, Laurena; Holmes, Avram J.; Johansson, Stefan; Jönsson, Erik Gunnar; Hellard, Stephanie Francoise Claire Le; Lundervold, Arvid; Lundervold, Astri J.; Moberget, Torgeir; Nordvik, Jan Egil; Sando, Sigrid Botne; Steen, Vidar Martin; Tamnes, Christian Krog; Agartz, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole; Homuth, Georg; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E.; Ikeda, Masashi; Jahanshad, Neda; Jockwitz, Christiane; Jørgensen, Niklas R.; Kikuchi, Masataka; Knowles, Emma E. M.; Kumar, Kuldeep; Leu, Costin; Linden, David E. J.; Liu, Jingyu; Maillard, Anne M.; Martin, Nicholas G.; Martin-Brevet, Sandra; Mather, Karen A.; Mathias, Samuel R.; McMahon, Katie L.; McRae, Allan F.; Medland, Sarah E.; Meyer-Lindenberg, Andreas; Modenato, Claudia; Monereo Sánchez, Jennifer; Morris, Derek W.; Mühleisen, Thomas W.; Murray, Robin M.; Nielsen, Jacob; Nyberg, Lars; Olde Loohuis, Loes M.; Ophoff, Roel A.; Owen, Michael J.; Paus, Tomas; Pausova, Zdenka; Peralta, Juan M.; Pike, G. Bruce; Prieto, Carlos; Quinlan, Erin B.; Reinbold, Céline S.; Reis Marques, Tiago; Rucker, James J. H.; Sachdev, Perminder S.; Schofield, Peter R.; Schork, Andrew J.; Schumann, Gunter; Shin, Jean; Shumskaya, Elena; Silva, Ana I.; Sisodiya, Sanjay M.; Stein, Dan J.; Strike, Lachlan T.; Suzuki, Ikuo K.; Teumer, Alexander; Thalamuthu, Anbupalam; Tordesillas-Gutiérrez, Diana; Uhlmann, Anne; Ulfarsson, Magnus O.; van ‘t Ent, Dennis; van den Bree, Marianne B. M.; Vanderhaeghen, Pierre; Vassos, Evangelos; Wen, Wei; Wittfeld, Katharina; Wright, Margaret J.; Stefansson, Hreinn; Stefansson, Kari; Jacquemont, Sébastien; Thompson, Paul M. (Journal article; Peer reviewed, 2021)
    Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...
  • Improving Sequential Decisions – Efficiently Accounting for Future Learning 

    Wang, Lingya; Oliver, Dean (Journal article; Peer reviewed, 2021)
    In sequential field development planning, past decisions not only directly affect the maximum achievable expected NPV but also influence the future information that can be used to reduce geological uncertainty. To act ...
  • Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response 

    Akkouh, Ibrahim; Hribkova, Hana; Grabiec, Marta; Budinska, Eva; Szabo, Attila; Kasparek, Tomas; Andreassen, Ole Andreas; Sun, Yuh-Man; Djurovic, Srdjan (Journal article; Peer reviewed, 2021)
    Astrocytes are the most abundant cell type in the human brain and are important regulators of several critical cellular functions, including synaptic transmission. Although astrocytes are known to play a central role in ...
  • Ways of counting in Micronesia 

    Bender, Andrea; Beller, Sieghard (Journal article; Peer reviewed, 2021)
    In many languages in Micronesia, clever ways of extending their counting systems to numbers far beyond imagination were developed in precolonial times. Here, we provide an exhaustive overview of these systems, highlight ...
  • The Climate Response to Emissions Reductions Due to COVID-19: Initial Results From CovidMIP 

    Jones, Chris D.; Hickman, Jonathan; Rumbold, Steven T; Walton, Jeremy; Lamboll, Robin; Skeie, Ragnhild Bieltvedt; Fiedler, Stephanie; Forster, Piers M.; Rogelj, Joeri; Abe, Manabu; Botzet, Michael; Calvin, Katherine; Cassou, Christophe; Cole, Jason N S; Davini, Paolo; Deushi, Makoto; Dix, Martin; Fyfe, John; Gillett, Nathan P.; Ilyina, Tatiana; Kawamiya, Michio; Kelley, Maxwell; Kharin, Slava; Koshiro, Tsuyoshi; Li, Hongmei; MacKallah, Chloe; Müller, Wolfgang A.; Nabat, Pierre; Van Noije, Twan; Nolan, Paul; Ohgaito, Rumi; Oliviè, Dirk Jan Leo; Oshima, Naga; Parodi, Jose; Reerink, Thomas J.; Ren, Lili; Romanou, Anastasia; Séférian, Roland; Tang, Yangming; Timmreck, Claudia; Tjiputra, Jerry; Tourigny, Etienne; Tsigaridis, Kostas; Wang, Hailong; Wu, Mingxuan; Wyser, Klaus; Yang, Shuting; Yang, Yang; Ziehn, Tilo (Journal article; Peer reviewed, 2021)
    Many nations responded to the corona virus disease-2019 (COVID-19) pandemic by restricting travel and other activities during 2020, resulting in temporarily reduced emissions of CO2, other greenhouse gases and ozone and ...
  • Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank 

    O'Connell, Kevin S.; Sønderby, Ida Elken; Frei, Oleksandr; van der Meer, Dennis; Athanasiu, Lavinia; Smeland, Olav Bjerkehagen; Alnæs, Dag; Kaufmann, Tobias; Westlye, Lars Tjelta; Steen, Vidar Martin; Andreassen, Ole Andreas; Hughes, Timothy; Djurovic, Srdjan (Journal article; Peer reviewed, 2021)
    Background Altered expression of the complement component C4A gene is a known risk factor for schizophrenia. Further, predicted brain C4A expression has also been associated with memory function highlighting that altered ...
  • The anatomic centers of the femoral and tibial insertions of the anterior cruciate ligament: a systematic review of imaging and cadaveric studies reporting normal center locations 

    Parkar, Anagha P; Adriaensen, Miraude E.A.M.P.; Vindfeld, Søren; Solheim, Eirik (Journal article; Peer reviewed, 2016)
    Background: The anterior cruciate ligament (ACL) is regularly reconstructed if knee joint function is impaired. Anatomic graft tunnel placement, often assessed with varying measurement methods, in the femur and tibia is ...
  • Capacity Building for a Stronger Workforce in the Public Healthcare Sector 

    Netteland, Grete; Hansen, Cecilie Johanne Slokvik; Wasson, Barbara (Journal article; Peer reviewed, 2021)
    In a more and more demanding sector, healthcare leaders are in need of relevant and up-to-date competencies. The paper describes the iComPAss-project that aimed to increase the quality of a Master’s programme for healthcare ...
  • Sex-Specific Associations between Blood Pressure and Risk of Atrial Fibrillation Subtypes in the Tromsø Study 

    Espnes, Hilde; Ball, Jocasta; Løchen, Maja-Lisa; Wilsgaard, Tom; Njølstad, Inger; Mathiesen, Ellisiv B; Gerdts, Eva; Sharashova, Ekaterina (Journal article; Peer reviewed, 2021)
    The aim of this study was to explore sex-specific associations between systolic blood pressure (SBP), hypertension, and the risk of incident atrial fibrillation (AF) subtypes, including paroxysmal, persistent, and permanent ...
  • Rapid climate changes during the Lateglacial and the early Holocene as seen from plant community dynamics in the Polar Urals, Russia 

    Bjune, Anne E.; Greve Alsos, Inger; Brendryen, Jo; Edwards, Mary E.; Haflidason, Haflidi; Johansen, Maren S.; Mangerud, Jan; Paus, Aage; Regnéll, Carl; Svendsen, John-Inge; Clarke, Charlotte L. (Journal article; Peer reviewed, 2021)
    A detailed, well-dated record of pollen and sedimentary ancient DNA (sedaDNA) for the period 15 000–9500 cal a bp describes changes at Lake Bolshoye Shchuchye in the Polar Ural Mountains, located far east of the classical ...
  • A multilevel dataset of microplastic abundance in the world’s upper ocean and the Laurentian Great Lakes 

    Isobe, Atsuhiko; Azuma, Takafumi; Cordova, Muhammad Reza; Cózar, Andrés; Galgani, Francois; Hagita, Ryuichi; Kanhai, La Daana; Imai, Keiri; Iwasaki, Shinsuke; Kako, Shin’ichro; Kozlovskii, Nikolai; Lusher, Amy L; Mason, Sherri A; Michida, Yutaka; Mituhasi, Takahisa; Morii, Yasuhiro; Mukai, Tohru; Popova, Anna; Shimizu, Kenichi; Tokai, Tadashi; Uchida, Keiichi; Yagi, Mitsuharu; Zhang, Weiwei (Journal article, 2021)
    A total of 8218 pelagic microplastic samples from the world’s oceans were synthesized to create a dataset composed of raw, calibrated, processed, and gridded data which are made available to the public. The raw microplastic ...
  • Short-term outcome after open-heart surgery for severe chronic rheumatic heart disease in a low-income country, with comparison with an historical control group: an observational study 

    Hauge, Ståle Wågen; Dalen, Havard; Estensen, Mette-Elise; Persson, Robert Matongo; Abebe, Sintayehu; Mekonnen, Desalew; Nega, Berhanu; Solholm, Atle; Farstad, Marit; Bogale, Nigussie; Graven, Torbjorn; Nielssen, Niels-Erik; Brekke, Hege Kristin; Vikenes, Kjell; Haaverstad, Rune (Journal article; Peer reviewed, 2021)
    Objectives Rheumatic heart disease (RHD) is a major burden in low-income and middle-income countries (LMICs). Cardiac surgery is the only curative treatment. Little is known about patients with severe chronic RHD operated ...

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