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Ruthenium-based antitumor drugs and delivery systems from monotherapy to combination therapy
(Journal article; Peer reviewed, 2022)Ruthenium complex is an important compound group for antitumor drug research and development. NAMI-A, KP1019, TLD1433 and other ruthenium complexes have entered clinical research. In recent years, the research on ruthenium ... -
Development of lung diffusion to adulthood following extremely preterm birth
(Journal article; Peer reviewed, 2022)Background: Gas exchange in extremely preterm (EP) infants must take place in fetal lungs. Childhood lung diffusing capacity of the lung for carbon monoxide (DLCO) is reduced; however, longitudinal development has not been ... -
Benthic invertebrates in Svalbard fjords—when metabarcoding does not outperform traditional biodiversity assessment
(Journal article; Peer reviewed, 2022)To protect and restore ecosystems and biodiversity is one of the 10 challenges identified by the United Nations’s Decade of the Ocean Science. In this study we used eDNA from sediments collected in two fjords of the Svalbard ... -
“Death audit is a fight” – provider perspectives on the ethics of the Maternal and Perinatal Death Surveillance and Response (MPDSR) system in Ethiopia
(Journal article; Peer reviewed, 2022)Background Maternal and neonatal health are regarded as important indicators of health in most countries. Death auditing through, for example, the Maternal and Perinatal Death Surveillance and Response (MPDSR) is viewed ... -
Simulation-based team-training in acute stroke: Is it safe to speed up?
(Journal article; Peer reviewed, 2022)Background In acute ischemic stroke (AIS), rapid treatment with intravenous thrombolysis (IVT) is crucial for good clinical outcome. Weekly simulation-based team-training of the stroke treatment team was implemented, ... -
Gaussian mixture models reveal highly diverse targeting tactics in a coastal fishing fleet
(Journal article; Peer reviewed, 2022)Fishermen make repeated choices with respect to when, where, and how to catch their target species. While these targeting tactics—and the factors shaping them—are known to fishers and some experts, knowledge about them is ... -
Births and deaths in Sidama in southern Ethiopia: findings from the 2018 Dale-Wonsho Health and Demographic Surveillance System (HDSS)
(Journal article; Peer reviewed, 2020)Background: Sidama is one of the most densely populated areas in Ethiopia. Information about the demographic characteristics is scarce, and most studies were census based on interviews. Earlier population studies from ... -
Hot towels: The bedrock of Meibomian gland dysfunction treatment – A review
(Journal article; Peer reviewed, 2022)Background Meibomian gland dysfunction (MGD) reduces quality-of-life and hinders work productivity of millions of patients, with high direct and indirect societal costs. Thickened meibum obstructs the glands and disrupts ... -
Brain‑correlates of processing local dependencies within a statistical learning paradigm
(Journal article; Peer reviewed, 2022)Statistical learning refers to the implicit mechanism of extracting regularities in our environment. Numerous studies have investigated the neural basis of statistical learning. However, how the brain responds to violations ... -
Association of oral bacteria with oral hygiene habits and self-reported gingival bleeding
(Journal article; Peer reviewed, 2022)Aim To describe associations of gingival bacterial composition and diversity with self-reported gingival bleeding and oral hygiene habits in a Norwegian regional-based population. Materials and Methods We examined the ... -
Crisis leadership in COVID-19: A qualitative study of Norwegian business leaders
(Journal article; Peer reviewed, 2022)Background: On March 11, 2020, the World Health Organization declared the novel coronavirus outbreak a global pandemic. The crisis that follows presented significant adverse challenges for organizations and business leaders ... -
Exploring stop signal reaction time over two sessions of the anticipatory response inhibition task
(Journal article; Peer reviewed, 2022)Various behavioural tasks measure response inhibition encompassing the ability to cancel unwanted actions, evaluated via stop signal reaction time (SSRT). It is unclear whether SSRT is an unchangeable inherent measure of ... -
Self-reported symptoms of anxiety and depression in chronic stroke patients with and without aphasia
(Journal article; Peer reviewed, 2017)Background: About half of the stroke population suffers from emotional difficulties, such as anxiety and depression post-stroke. Acquiring aphasia is seen to increase the risk of developing symptoms of emotional difficulties ... -
VACCELERATE Volunteer Registry: A European study participant database to facilitate clinical trial enrolment
(Journal article; Peer reviewed, 2022)Introduction: The coronavirus disease 2019 (COVID-19) pandemic has evidenced the key role of vaccine design, obtention, production and administration to successfully fight against infectious diseases and to provide efficient ... -
Host Transcriptional Signatures Predict Etiology in Community-Acquired Pneumonia: Potential Antibiotic Stewardship Tools
(Journal article; Peer reviewed, 2022)Background: Current approaches for pathogen identification in community-acquired pneumonia (CAP) remain suboptimal, leaving most patients without a microbiological diagnosis. If better diagnostic tools were available for ... -
Algorithmic failure as a humanities methodology: Machine learning’s mispredictions identify rich cases for qualitative analysis
(Journal article; Peer reviewed, 2022)This commentary tests a methodology proposed by Munk et al. (2022) for using failed predictions in machine learning as a method to identify ambiguous and rich cases for qualitative analysis. Using a dataset describing ... -
Differences in lung function, bronchial hyperresponsiveness and respiratory health between elite athletes competing in different sports
(Journal article; Peer reviewed, 2022)The aim of this study was to examine lung function, bronchial hyperresponsiveness (BHR) and exercise-induced respiratory symptoms in elite athletes performing different sports. Norwegian national-team athletes (30 swimmers, ... -
Shared genetic loci between depression and cardiometabolic traits
(Journal article; Peer reviewed, 2022-05-13)Epidemiological and clinical studies have found associations between depression and cardiovascular disease risk factors, and coronary artery disease patients with depression have worse prognosis. The genetic relationship ... -
Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1
(Journal article; Peer reviewed, 2022-06-02)Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. In different conditions, macrophage polarization can be induced by high-mobility group ... -
Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections
(Journal article; Peer reviewed, 2022)Background: Necrotising soft tissue infections (NSTIs) are rapidly progressing bacterial infections usually caused by either several pathogens in unison (polymicrobial infections) or Streptococcus pyogenes (mono-microbial ...
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