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Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function
(Journal article; Peer reviewed, 2022)Objective: Neonatal lupus erythematosus (NLE) may develop after transplacental transfer of maternal autoantibodies with cardiac manifestations (congenital heart block, CHB) including atrioventricular block, atrial and ... -
Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes
(Journal article; Peer reviewed, 2022-05-05)Persons with type 2 diabetes born in the regions of famine exposures have disproportionally elevated risk of vision-threatening proliferative diabetic retinopathy (PDR) in adulthood. However, the underlying mechanisms are ... -
The value of histological examination in the diagnosis of tuberculous lymphadenitis in the era of rapid molecular diagnosis
(Journal article; Peer reviewed, 2022)Extrapulmonary tuberculosis often poses a diagnostic challenge. This study aimed to assess the value of histological examination in diagnosing tuberculous lymphadenitis (LNTB) when performed simultaneously with rapid ... -
Stable Southern Hemisphere westerly winds throughout the Holocene until intensification in the last two millennia
(Journal article; Peer reviewed, 2022)The Southern Hemisphere westerly winds sustain the Southern Ocean’s role as one of Earth’s main carbon sinks, and have helped sequester nearly half the anthropogenic CO2 stored in the ocean. Observations show shifts in the ... -
Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes
(Journal article; Peer reviewed, 2022)Improved models of experimental diabetes are needed to develop cell therapies for diabetes. Here, we introduce the B6 RIP-DTR mouse, a model of experimental diabetes in fully immunocompetent animals. These inbred mice ... -
Prematur ovarialinsuffisiens
(Journal article; Peer reviewed, 2022)Prematur ovarialinsuffisiens defineres som tap av ovariefunksjon før 40 års alder og er en kompleks tilstand med heterogen etiologi. Tidlig diagnose og igangsetting av hormonerstattende behandling er viktig for å lindre ... -
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
(Journal article; Peer reviewed, 2022)We investigated genomic and transcriptomic changes in paired tumor samples of 29 in-house multiple myeloma (MM) patients and 28 patients from the MMRF CoMMpass study before and after treatment. A change in clonal composition ... -
Physician participation in quality improvement work- interest and opportunity: a cross-sectional survey
(Journal article; Peer reviewed, 2022-10-25)Background: Lack of physician involvement in quality improvement threatens the success and sustainability of quality improvement measures. It is therefore important to assess physicians´ interests and opportunities to be ... -
Geographical variation in orthopedic procedures in Norway: Cross-sectional population-based study
(Journal article; Peer reviewed, 2022)Background: Standardized surgery rates for common orthopedic procedures vary across geographical areas in Norway. We explored whether area-level factors related to demand and supply in publicly funded healthcare are ... -
MRI adipose tissue segmentation and quantification in R (RAdipoSeg)
(Journal article; Peer reviewed, 2022-10-08)Background: Excess adipose tissue is associated with increased cardiovascular and metabolic risk, but the volume of visceral and subcutaneous adipose tissue poses different metabolic risks. MRI with fat suppression can be ... -
Assessment of Small Bowel Motility and SMA Blood Flow Studied with Transabdominal Ultrasound
(Journal article; Peer reviewed, 2022)Purpose: Gastrointestinal ultrasound (GIUS) is a noninvasive imaging technique that may be used to study physiological changes in the small bowel. The aim of the study was to investigate the feasibility of measuring blood ... -
Hypersementose og endodontiske implikasjoner
(Journal article; Peer reviewed, 2022)Hypersementose er forbundet med lokale og systemiske faktorer, men etiologien er ikke godt kartlagt. Vanskeligheter med å bedømme røntgenologisk tykkelse på sementlaget ved hypersementose, vil direkte kunne påvirke beslutning ... -
Impact of rapid molecular testing on diagnosis, treatment and management of community-acquired pneumonia in Norway: a pragmatic randomised controlled trial (CAPNOR)
(Journal article; Peer reviewed, 2022)Background: Community-acquired pneumonia (CAP) causes a large burden of disease. Due to difficulties in obtaining representative respiratory samples and insensitive standard microbiological methods, the microbiological ... -
Exploring seismic detection and resolution thresholds of fault zones and gas seeps in the shallow subsurface using seismic modelling
(Journal article; Peer reviewed, 2022)Seismic resolution and illumination issues are sources of challenges in the detailed imaging and detection of subsurface fault architecture and fluid migration. Improved constraints on resolution can provide input into ... -
Dietary practices and nutritional status of young children in the former ensete monoculture dominated Sidama region, southern Ethiopia: A community based cross-sectional study
(Journal article; Peer reviewed, 2022-09-14)Background: Child undernutrition is a challenge in Ethiopia, where morbidity and mortality among children are attributed to it. This study aimed to describe the dietary practices, household food insecurity, and nutritional ... -
Assessing the Anti-Inflammatory Effects of an Orally Dosed Enzymatically Liberated Fish Oil in a House Dust Model of Allergic Asthma
(Journal article; Peer reviewed, 2022-10-14)Eosinophils are a major driver of inflammation in a number of human diseases, including asthma. Biologic therapies targeting IL-5 have enabled better control of severe eosinophilic asthma, but no such advances have been ... -
Explaining Backlash: Social Hierarchy and Men’s Rejection of Women’s Rights Reforms
(Journal article; Peer reviewed, 2022)Governments promote gender-sensitive policies, yet little is known about why reform campaigns evoke backlash. Drawing on social position theory, we test whether marginalized (women’s organizations) or intrusive (Western ... -
Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment
(Journal article; Peer reviewed, 2022)Background: We have previously reported that the safety and efficacy of ipilimumab in real-world patients with metastatic melanoma were comparable to clinical trials. Few studies have explored health-related quality of ... -
Plasma unmetabolized folic acid in pregnancy and risk of autistic traits and language impairment in antiseizure medication-exposed children of women with epilepsy
(Journal article; Peer reviewed, 2022)Background: Fetal exposure to unmetabolized folic acid (UMFA) during pregnancy may be associated with adverse neurodevelopment. Antiseizure medication (ASM) may interact with folate metabolism. Women with epilepsy using ... -
Multiomics in the central Arctic Ocean for benchmarking biodiversity change
(Journal article; Peer reviewed, 2022-10-17)Multiomics approaches need to be applied in the central Arctic Ocean to benchmark biodiversity change and to identify novel species and their genes. As part of MOSAiC, EcoOmics will therefore be essential for conservation ...
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