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  • Potential Transcriptional Biomarkers to Guide Glucocorticoid Replacement in Autoimmune Addison's Disease 

    Sævik, Åse Bjorvatn; Wolff, Anette Susanne Bøe; Björnsdottir, Sigridur; Simunkova, Katerina; Hynne, Martha Schei; Dolan, David William Peter; Bratland, Eirik; Knappskog, Per M; Methlie, Paal; Carlsen, Siri; Isaksson, Magnus; Bensing, Sophie; Kämpe, Olof; Husebye, Eystein S; Løvås, Kristian; Øksnes, Marianne (Journal article; Peer reviewed, 2021)
    Background No reliable biomarkers exist to guide glucocorticoid (GC) replacement treatment in autoimmune Addison’s disease (AAD), leading to overtreatment with alarming and persistent side effects or undertreatment, which ...
  • Sex-Specific Limitations in Physical Health in Primary Adrenal Insufficiency 

    Didriksen, Nora Møller; Sævik, Åse Bjorvatn; Sortland, Linn Solveig; Øksnes, Marianne; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2021)
    Background: Patients with primary adrenal insufficiency (PAI) suffer reduced quality of life (QoL), but comparisons with large-scale normative data are scarce. The clinical characteristics associated with reduced QoL are ...
  • Transport of mafic magma through the crust and sedimentary basins: Jameson Land, East Greenland 

    Eide, Christian Haug; Schofield, Nick; Howell, John Anthony; Jerram, Dougal Alexander (Journal article; Peer reviewed, 2021)
    Igneous sheet-complexes transport magma through the crust, but most studies have focused on single segments of the magma transport system or have low resolution. In the Jameson Land Basin in East Greenland, seismic reflection ...
  • A nonlinear multi-scale model for blood circulation in a realistic vascular system 

    Qohar, Ulin Nuha Abdul; Munthe-Kaas, Antonella Zanna; Nordbotten, Jan Martin; Hanson, Erik Andreas (Journal article; Peer reviewed, 2021)
    In the last decade, numerical models have become an increasingly important tool in biological and medical science. Numerical simulations contribute to a deeper understanding of physiology and are a powerful tool for better ...
  • Epistemic uncertainty quantification in deep learning classification by the Delta method 

    Nilsen, Geir Kjetil; Munthe-Kaas, Antonella Zanna; Skaug, Hans Julius; Brun, Morten (Journal article; Peer reviewed, 2021)
    The Delta method is a classical procedure for quantifying epistemic uncertainty in statistical models, but its direct application to deep neural networks is prevented by the large number of parameters . We propose a low ...
  • Analysis of multiple scattering errors in LISST-VSF volume scattering function measurements using Monte Carlo simulations and experimental data 

    Ugulen, Håvard Stavn; Sandven, Håkon; Hamre, Børge; Kristoffersen, Arne Skodvin; Sætre, Camilla (Journal article; Peer reviewed, 2021)
    A Monte Carlo algorithm has been developed to investigate the effects of multiple scattering on the volume scattering function measured by the LISST-VSF instrument. The developed algorithm is compared to experimental results ...
  • Phosphatidylserine receptors enhance SARS-CoV-2 infection 

    Bohan, Dana; Van Ert, Hanora; Ruggio, Natalie; Rogers, Kai J; Badreddine, Mohammad; Aguilar Briseno, José A; Elliff, Jonah; Rojas Chavez, Roberth Anthony; Gao, Boning; Stokowy, Tomasz; Christakou, Eleni; Kursula, Petri; Micklem, David Robert; Gausdal, Gro; Haim, Hillel; Minna, John; Lorens, James Bradley; Maury, Wendy (Journal article; Peer reviewed, 2021)
    Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through virion-associated PS binding that is termed apoptotic mimicry. Here we show that this broadly shared uptake mechanism is utilized by ...
  • Toxicity assessment of urban marine sediments from Western Norway using a battery of stress-activated receptors and cell-based bioassays from fish 

    Goksøyr, Siri Øfsthus; Sørensen, Helene; Grøsvik, Bjørn Einar; Pampanin, Daniela Maria; Goksøyr, Anders; Karlsen, Odd André (Journal article; Peer reviewed, 2021)
    A luciferase reporter gene-based bioassay battery consisting of stress-activated receptors from fish, complemented with traditional fish cell-based bioassays, were used to assess the toxicity of marine sediment samples ...
  • Melt volume at Atlantic volcanic rifted margins controlled by depth-dependent extension and mantle temperature 

    Lu, Gang; Huismans, Ritske Sipke (Journal article; Peer reviewed, 2021)
    Breakup volcanism along rifted passive margins is highly variable in time and space. The factors controlling magmatic activity during continental rifting and breakup are not resolved and controversial. Here we use numerical ...
  • When young children grieve: Supporting daycare children following bereavement — A parent’s perspective 

    Lytje, Martin; Dyregrov, Atle (Journal article; Peer reviewed, 2021)
    Thirteen parents who lost the mother or father to their child were interviewed, using semi-structured interviews. Participants reflect on their young children’s (3–6) grief, support needs, and what they learned from this ...
  • Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry 

    Kulkarni, Amit; Ferreira, Tiago; Bretscher, Clemens; Grewenig, Annabel; El-Andaloussi, Nazim; Bonifati, Serena; Marttila, Tiina; Palissot, Valèrie; Hossain, Jubayer A.; Azuaje, Francisco; Miletic, Hrvoje; Ystaas, Lars Andreas Rømo; Golebiewska, Anna; Niclou, Simone Pierrette; Roeth, Ralf; Niesler, Beate; Weiss, Amélie; Brino, Laurent; Marchini, Antonio (Journal article; Peer reviewed, 2021)
    H-1 parvovirus (H-1PV) is a promising anticancer therapy. However, in-depth understanding of its life cycle, including the host cell factors needed for infectivity and oncolysis, is lacking. This understanding may guide ...
  • Current status of thulium fibre laser lithotripsy: an up-to-date review 

    Jones, Patrick; Beisland, Christian; Ulvik, Øyvind (Journal article; Peer reviewed, 2021)
    Objective To perform an up-to-date review to scope the current status of the thulium fibre laser (TFL) in the setting of stone lithotripsy and provide a guide for the clinical urologist. Methods A review of world ...
  • Ion transporters and osmoregulation in the kidney of teleost fishes as a function of salinity 

    Takvam, Marius; Wood, Chris M.; Kryvi, Harald; Nilsen, Tom Ole (Journal article; Peer reviewed, 2021-04-20)
    Euryhaline teleosts exhibit major changes in renal function as they move between freshwater (FW) and seawater (SW) environments, thus tolerating large fluctuations in salinity. In FW, the kidney excretes large volumes of ...
  • How Does Implant Survivorship Vary with Different Corail Femoral Stem Variants? Results of 51,212 Cases with Up to 30 Years Of Follow-up from the Norwegian Arthroplasty Register 

    Melbye, Silje Marie; Haug, Sofie Cecilia Dietrich; Fenstad, Anne Marie; Furnes, Ove Nord; Gjertsen, Jan-Erik; Hallan, Geir (Journal article; Peer reviewed, 2021)
    Background: The Corail® cementless stem (DePuy Synthes) has been used in Norway since 1987 and is one of the most frequently used stems in THA worldwide. Although the published survival results of the standard Corail stem ...
  • The social dilemma in artificial intelligence development and why we have to solve it 

    Strümke, Inga; Slavkovik, Marija; Madai, Vince Istvan (Journal article; Peer reviewed, 2021)
    While the demand for ethical artificial intelligence (AI) systems increases, the number of unethical uses of AI accelerates, even though there is no shortage of ethical guidelines. We argue that a possible underlying cause ...
  • The effect of Zhang’s guideline versus the WHO partograph on childbirth experience measured by the Childbirth Experience Questionnaire in the Labor Progression Study (LaPS): A cluster randomized trial 

    Rozsa, Daniella Judit; Dalbye, Rebecka; Bernitz, Stine; Blix, Ellen; Dalen, Ingvild; Braut, Geir Sverre; Eggebø, Torbjørn Moe; Øian, Pål; Sande, Ragnar Kvie (Journal article; Peer reviewed, 2021)
    Introduction Childbirth experience is an increasingly recognized and important measure of quality of obstetric care. Previous research has shown that it can be affected by intrapartum care and how labor is followed. A ...
  • Syn-rift sediment gravity flow deposition on a Late Jurassic fault-terraced slope, northern North Sea 

    Tillmans, Fabian; Gawthorpe, Robert Leslie; Jackson, Christopher AL; Rotevatn, Atle (Journal article; Peer reviewed, 2021)
    Structurally controlled bathymetry in rifts has a significant influence on sediment routing pathways and depositional architecture of sediment gravity flow deposits. In contrast to rift segments characterized by crustal-scale ...
  • Mental health responses to COVID-19 around the world 

    Olff, Miranda; Primasari, Indira; Qing, Yulan; Coimbra, Bruno M.; Hovnanyan, Ani; Grace, Emma; Williamson, Rachel E.; Hoeboer, Chris M.; Aakvaag, Helene Flood; Ajdukovic, Dean; Anastassiou-Hadjicharalambous, Xenia; Bakker, Anne; Bröcker, Erine E.; Cantoni, Lucia; Cloitre, Marylène; de Soir, Erik LJL; Dragan, Małgorzata; Dyregrov, Atle; El-Hage, Wissam; Ford, Julian D.; Haagsma, Juanita A.; Javakhishvili, Jana D.; Kassam-Adams, Nancy; Kristensen, Christian H.; Langevin, Rachel; Lanza, Juliana A.; Lueger-Schuster, Brigitte; Manickam, Leister S. S.; Marengo, Davide; Mello, Marcelo F.; Nickerson, Angela; Oe, Misari; Ozgen, Mihriban Heval; Rabellino, Daniela; Sales, Luisa; Salgado, Carolina; Schellong, Julia; Schnyder, Ulrich; Seedat, Soraya; Semenova, Nadezhda B.; Smith, Andrew J.; Sobczak, Sjacko; ter Heide, Jackie June; Vazquez, Carmelo; Videira Pinto, Janaina; Wagner, Anne C.; Wang, Li; Zrnic, Irina (Journal article; Peer reviewed, 2021)
    Background: The mental health impact of the COVID-19 crisis may differ from previously studied stressful events in terms of psychological reactions, specific risk factors, and symptom severity across geographic regions ...
  • Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs 

    Shanbhag, Siddharth; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Yassin, Mohammed Ahmed Alamin Yousif; Dongre, Harsh Nitin; Costea, Daniela Elena; Tangl, Stefan; Stavropoulos, Andreas; Bolstad, Anne Isine; Suliman, Salwa; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021-11-30)
    Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation and bone regeneration capacity of mesenchymal stromal cells (MSC). Gingiva-derived progenitor cells (GPC) represent a less invasive alternative ...

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