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  • Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars) 

    Söderström, Sofie Karin; Lille-Langøy, Roger; Yadetie, Fekadu; Rauch, Mateusz; Milinski, Ana; Dejaegere, Annick; Stote, Roland H.; Goksøyr, Anders; Karlsen, Odd André (Journal article; Peer reviewed, 2022)
    Toxicity mediated by per- and polyfluoroalkyl substances (PFAS), and especially perfluoroalkyl acids (PFAAs), has been linked to activation of peroxisome proliferator-activated receptors (Ppar) in many vertebrates. Here, ...
  • Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy 

    Nielsen, Hans Jørgen; Nedrebø, Bjørn Gunnar; Fosså, Alexander; Andersen, John Roger; Assmus, Jörg; Dagsland, Vigdis Halvorsen; Dankel, Simon N; Gudbrandsen, Oddrun Anita; Fernø, Johan; Hjellestad, Iren Drange; Hjermstad, Marianne Jensen; Kolotkin, Ronette Loganzo; Thorsen, Håvard Luong; Mellgren, Gunnar; Flølo, Tone Nygaard (Journal article; Peer reviewed, 2022)
    Background/objectives There is limited long-term data comparing the outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, both with respect to body weight, quality of life (QOL) and ...
  • Longitudinal visualization for exploratory analysis of multiple sclerosis lesions 

    Sugathan, Sherin; Bartsch, Hauke; Riemer, Frank; Grüner, Eli Renate; Lawonn, Kai; Smit, Noeska Natasja (Journal article; Peer reviewed, 2022)
    In multiple sclerosis (MS), the amount of brain damage, anatomical location, shape, and changes are important aspects that help medical researchers and clinicians to understand the temporal patterns of the disease. Interactive ...
  • Disease-Course Adapting Machine Learning Prognostication Models in Elderly Patients Critically Ill With COVID-19: Multicenter Cohort Study With External Validation 

    Jung, Christian; Mamandipoor, Behrooz; Fjølner, Jesper; Bruno, Raphael Romano; Wernly, Bernhard; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter V.; Szczeklik, Wojciech; Czuczwar, Miroslaw; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans Kristian; Osmani, Venet (Journal article; Peer reviewed, 2022)
    Background:The COVID-19 pandemic caused by SARS-CoV-2 is challenging health care systems globally. The disease disproportionately affects the elderly population, both in terms of disease severity and mortality risk. ...
  • Acidification of the Nordic Seas 

    Fransner, Sara Filippa Krusmynta; Fröb, Friederike; Tjiputra, Jerry; Goris, Nadine; Lauvset, Siv Kari; Skjelvan, Ingunn; Jeansson, Emil; Omar, Abdirahman; Chierici, Melissa; Jones, Elizabeth Marie; Fransson, Agneta; Ólafsdóttir, Sólveig R.; Johannessen, Truls; Olsen, Are (Journal article; Peer reviewed, 2022)
    Due to low calcium carbonate saturation states, and winter mixing that brings anthropogenic carbon to the deep ocean, the Nordic Seas and their cold-water corals are vulnerable to ocean acidification. Here, we present a ...
  • Rapid post-glacial bedrock weathering in coastal Norway 

    Andersen, Jane Lund; Margreth, Annina; Fredin, Ola; Linge, Henriette; Goodfellow, Bradley W.; Faust, Johan Christoph; Knies, Jochen; Solbakk, Terje; Brook, Edward J.; Scheiber, Thomas; van der Lelij, Roelant; Burki, Valentin Josef; Rubensdotter, Brita Lena Eleonor Fredin; Himmler, Tobias; Yesilyurt, Serdar; Christl, Marcus; Vockenhuber, Christof; Akcar, Naki (Journal article; Peer reviewed, 2022)
    Quantifying bedrock weathering rates under diverse climate conditions is essential to understanding timescales of landscape evolution. Yet, weathering rates are often difficult to constrain, and associating a weathered ...
  • Anti-PD-L1/TGF-βR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer 

    Cheng, Bo; Ding, Kaikai; Chen, Pengxiang; Ji, Jianxiong; Luo, Tao; Guo, Xiaofan; Qiu, Wei; Ma, Chunhong; Meng, Xue; Wang, Jian; Yu, Jinming; Liu, Yuan (Journal article, 2022)
    Background Second-generation programmed cell death-protein 1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors, such as bintrafusp alfa (M7824), SHR-1701, and YM101, have been developed to simultaneously block PD-1/PD-L1 ...
  • Climate resilience and the human-water dynamics. The case of tomato production in Morocco 

    Benabderrazik, Kenza; Kopainsky, Birgit; Monastyrnaya, Elena; Thompson, William; Tazi, L.; Jörin, Jonas; Six, Johan (Journal article; Peer reviewed, 2022)
    In Morocco, droughts are an increasing threat affecting water availability, agricultural production and producers' livelihoods. Moreover, water demand for irrigation has led to overexploitation of the groundwater table ...
  • Changes in eicosapentaenoic acid and docosahexaenoic acid and risk of cardiovascular events and atrial fibrillation: A secondary analysis of the OMEMI trial 

    Myhre, Peder Langeland; Kalstad, Are; Tveit, Sjur Hansen; Laake, Kristian; Schmidt, Erik B.; Smith, Pål; Nilsen, Dennis W.T.; Tveit, Arnljot; Solheim, Svein; Arnesen, Harald; Seljeflot, Ingebjørg (Journal article; Peer reviewed, 2022)
    Background The cardiovascular benefit from n-3 polyunsaturated fatty acids (PUFAs) after acute myocardial infarction (AMI) is controversial, and the importance of serum eicosapentaenoic acid (EPA) and docosahexaenoic acid ...
  • The effect of gadolinium-based contrast-agents on automated brain atrophy measurements by FreeSurfer in patients with multiple sclerosis 

    Lie, Ingrid Anne; Kerklingh, Emma; Wesnes, Kristin; van Nederpelt, David R.; Brouwer, Iman; Torkildsen, Øivind; Myhr, Kjell-Morten; Barkhof, Frederik; Bø, Lars; Vrenken, Hugo (Journal article; Peer reviewed, 2022)
    Objective To determine whether reliable brain atrophy measures can be obtained from post-contrast 3D T1-weighted images in patients with multiple sclerosis (MS) using FreeSurfer. Methods Twenty-two patients with MS ...
  • In-office thermal systems for the treatment of dry eye disease 

    Beining, Marie Wangen; Magnø, Morten Scherven; Moschowits, Emily; Olafsson, Jonatan; Vehof, Jelle; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2022)
    Dry eye disease affects millions of people worldwide, causing pain, vision disturbance, and reduced productivity. Meibomian gland dysfunction, a major cause of dry eye, is characterized by chronic glandular inflammation, ...
  • Placental weight centiles adjusted for age, parity and fetal sex 

    Flatley, Christopher; Sole-Navais, Pol; Vaudel, Marc; Helgeland, Øyvind; Modzelewska, Dominika; Johansson, Stefan; Jacobsson, Bo; Njølstad, Pål Rasmus (Journal article; Peer reviewed, 2022)
    Introduction The weight of the placenta can be indicative of efficacy in nutrient and oxygen supply. Furthermore, it has been suggested that a measure of the placenta's ability to adequately supply nutrients to the fetus ...
  • Identification of microRNAs from medicinal plant Murraya Koenigii by high-throughput sequencing and their functional implications in secondary metabolite biosynthesis 

    Gutiérrez-García, Claudia; Ahmed, Shiek S. S. J.; Ramalingam, Sathishkumar; Selvaraj, Dhivya; Srivastava, Aashish; Paul, Sujay; Sharma, Ashutosh (Journal article; Peer reviewed, 2022)
    MicroRNAs (miRNAs) are small noncoding RNA molecules that play crucial post-transcriptional regulatory roles in plants, including development and stress-response signaling. However, information about their involvement in ...
  • Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction 

    Mundal, Siv Boon; Rakner, Johanne Johnsen; Silva, Gabriela; Gierman, Lobke; Austdal, Marie; Basnet, Purusotam; Elschot, Mattijs; Bakke, Siril Skaret; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Moses, Eric; Acharya, Ganesh; Bjørge, Line; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2022)
    Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are ...
  • Experiences of Norwegian Mothers Attending an Online Course of Therapeutic Writing Following the Unexpected Death of a Child 

    Lehmann, Olga V.; Neimeyer, Robert A.; Thimm, Jens; Hjeltnes, Aslak; Lengelle, Reinekke; Kalstad, Trine Giving (Journal article; Peer reviewed, 2022-01-27)
    The unexpected death of a child is one of the most challenging losses as it fractures survivors’ sense of parenthood and other layers of identity. Given that not all the bereaved parents who have need for support respond ...
  • Substantial Sparing of Organs at Risk with Modern Proton Therapy in Lung Cancer, but Altered Breathing Patterns Can Jeopardize Target Coverage 

    Boer, Camilla Grindeland; Fjellanger, Kristine; Sandvik, Inger Marie; Ugland, Maren; Engeseth, Grete May; Hysing, Liv Bolstad (Journal article; Peer reviewed, 2022-03-08)
    Enhancing treatment of locally advanced non-small cell lung cancer (LA-NSCLC) by using pencil beam scanning proton therapy (PBS-PT) is attractive, but little knowledge exists on the effects of uncertainties occurring between ...
  • Association of Excessive Sleepiness, Pathological Fatigue, Depression, and Anxiety With Different Severity Levels of Obstructive Sleep Apnea 

    Mjelle, Karin Elisabeth Sundt; Lehmann, Sverre; Saxvig, Ingvild W.; Gulati, Shashi; Bjorvatn, Bjørn (Journal article; Peer reviewed, 2022-03-31)
    Objective: The aim of this study was to investigate possible associations between obstructive sleep apnea and fatigue. This naturally led to considering the association between OSA and excessive sleepiness, depression, and ...
  • Basosquamous Basal Cell Carcinoma with Bone Marrow Metastasis 

    Thunestvedt, Lise Mayrin Økland; Helgeland, Lars; Bachmann, Ingeborg Margrethe; Karlsdottir, Åsa; Haslerud, Torjan Magne; Reikvam, Håkon (Journal article; Peer reviewed, 2022-03-23)
    Basal cell carcinoma (BCC) is the most common cancer in Caucasians. It is slow growing and rarely metastasizes. If left untreated over time, invasive growth can occur. We present a patient case with a primary BCC located ...
  • DeepOtolith v1.0: An Open-Source AI Platform for Automating Fish Age Reading from Otolith or Scale Images 

    Politikos, Dimitris V.; Sykiniotis, Nikolaos; Petasis, Georgios; Dedousis, Pavlos; Ordonez, Alba; Vabø, Rune; Anastasopoulou, Aikaterini; Moen, Endre; Mytilineou, Chryssi; Salberg, Arnt-Børre; Chatzispyrou, Archontia; Malde, Ketil (Journal article; Peer reviewed, 2022-05-29)
    Every year, marine scientists around the world read thousands of otolith or scale images to determine the age structure of commercial fish stocks. This knowledge is important for fisheries and conservation management. ...
  • Lifelong exposure to residential greenspace and the premenstrual syndrome: A population-based study of Northern European women 

    Triebner, Kai Philipp; Markevych, Iana; Bertelsen, Randi Jacobsen; Skottvoll, Bente Sved; Hustad, Simon Steinar; Forsberg, Bertil; Franklin, Karl A; Holm, Mathias; Lindberg, Eva; Heinrich, Joachim; Real, Francisco Gomez; Dadvand, Payam (Journal article; Peer reviewed, 2022)
    Background: The premenstrual syndrome (PMS) causes clinically relevant psychological and physical symptoms in up to 20% of women of reproductive age. To date, no studies have investigated the relationship between PMS and ...

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