• An environmentally benign and high-rate Appel type reaction 

  Fuenzalida, Nicolas Mattias del Rio; Alme, Eirin; Lundevall, Frida Johanne; Bjørsvik, Hans-René (Journal article; Peer reviewed, 2022)

  A high rate, selective, and productive Appel type reaction was developed. The method allows for ipso-substitution of the alcoholic hydroxy group with halogens ∈ [Cl, Br, I]. The method demands mild reaction conditions that ...

• Effectiveness of Internet-Based Cognitive Behavioral Therapy with Telephone Support for Noncardiac Chest Pain: Randomized Controlled Trial 

  Thesen, Terje; Himle, Joseph A.; Martinsen, Egil Wilhelm; Walseth, Liv Tveit; Thorup, Frode; Gallefoss, Frode; Jonsbu, Egil (Journal article; Peer reviewed, 2022)

  Background: Noncardiac chest pain has a high prevalence and is associated with reduced quality of life, anxiety, avoidance of physical activity, and high societal costs. There is a lack of an effective, low-cost, easy to ...

• Diagnostic stewardship aiming at expectorated or induced sputum promotes microbial diagnosis in community-acquired pneumonia 

  Waagsbø, Bjørn; Buset, Eva Margrethe; Longva, Jørn-Åge; Bjerke, Merete; Bakkene, Birgitte; Ertesvåg, Anne-Stine; Holmen, Hanne; Nikodojevic, Marko; Tran, To Thy; Christensen, Andreas; Nilsen, Einar; Damås, Jan Kristian; Heggelund, Lars (Journal article; Peer reviewed, 2022)

  Purpose: Studies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, ...

• Exercise Training in Duchenne Muscular Dystrophy: A Systematic Review and Meta-Analysis 

  Hammer, Stian; Toussaint, Michel; Vollsæter, Maria; Tvedt, Marianne Nesbjørg; Røksund, Ola Drange; Reychler, Gregory; Lund, Hans; Andersen, Tiina Maarit (Journal article; Peer reviewed, 2022)

  Objective: To evaluate the effects and safety of exercise training, and to determine the most effective exercise intervention for people with Duchenne muscular dystrophy. Exercise training was compared with no training, ...

• Predictive Agent-Based Crowd Model Design Using Decentralized Control Systems 

  Berceanu, Cristian; Banu, Ionut; Husebø, Bettina; Patrascu, Monica (Journal article; Peer reviewed, 2022)

  As a complex system, crowd dynamics emerge bottom-up from the local interactions between pedestrians as component subsystems. This article proposes a predictive agent-based crowd simulation model to analyze the outcomes ...

• Addressing the clinical unmet needs in primary Sjögren's Syndrome through the sharing, harmonization and federated analysis of 21 European cohorts 

  Pezoulas, Vasileios C.; Goules, Andreas; Kalatzis, Fanis; Chatzis, Luke; Kourou, Konstantina D.; Venetsanopoulou, Aliki; Exarchos, Themis P.; Gandolfo, Saviana; Votis, Konstantinos; Zampeli, Evi; Burmeister, Jan; May, Thorsten; Marcelino Pérez, Manuel; Lishchuk, Iryna; Chondrogiannis, Thymios; Andronikou, Vassiliki; Varvarigou, Theodora; Filipovic, Nenad; Tsiknakis, Manolis; Baldini, Chiara; Bombardieri, Michele; Bootsma, Hendrika; Bowman, Simon J.; Shahnawaz Soyfoo, Muhammad; Parisis, Dorian; Delporte, Christine; Devauchelle-Pensec, Valérie; Pers, Jacques-Olivier; Dörner, Thomas; Bartoloni, Elena; Gerli, Roberto; Giacomelli, Roberto; Jonsson, Roland; Ng, Wan-Fai; Priori, Roberta; Ramos-Casals, Manuel; Sivils, Kathy; Skopouli, Fotini; Torsten, Witte; A. G. van Roon, Joel; Xavier, Mariette; De Vita, Salvatore; Tzioufas, Athanasios G.; Fotiadis, Dimitrios I. (Journal article; Peer reviewed, 2022)

  For many decades, the clinical unmet needs of primary Sjögren’s Syndrome (pSS) have been left unresolved due to the rareness of the disease and the complexity of the underlying pathogenic mechanisms, including the ...

• Recurrence of postpartum hemorrhage, maternal and paternal contribution, and the effect of offspring birthweight and sex: a population-based cohort study 

  Linde, Lorentz Erland; Ebbing, Cathrine; Moster, Dag; Kessler, Jørg; Baghestan, Elham; Gissler, Mika; Rasmussen, Svein (Journal article; Peer reviewed, 2022)

  Purpose: This study examines individual aggregation of postpartum hemorrhage (PPH), paternal contribution and how offspring birthweight and sex influence recurrence of PPH. Further, we wanted to estimate the proportion of ...

• LRFN5 locus structure is associated with autism and influenced by the sex of the individual and locus conversions 

  Lybæk, Helle; Robson, Michael; de Leeuw, Nicole; Hehir-Kwa, Jayne Y.; Jeffries, Aaron; Haukanes, Bjørn Ivar; Berland, Siren; de Bruijn, Diederik; Mundlos, Stefan; Spielmann, Malte; Houge, Gunnar Douzgos (Journal article; Peer reviewed, 2022)

  LRFN5 is a regulator of synaptic development and the only gene in a 5.4 Mb mammalian-specific conserved topologically associating domain (TAD); the LRFN5 locus. An association between locus structural changes and developmental ...

• Kaplan-Meier and Cox Regression Are Preferable for the Analysis of Time to Revision of Joint Arthroplasty: Thirty-One Years of Follow-up for Cemented and Uncemented THAs Inserted from 1987 to 2000 in the Norwegian Arthroplasty Register 

  Lie, Stein Atle; Fenstad, Anne Marie; Lygre, Stein Håkon Låstad; Kroken, Gard; Dybvik, Eva Hansen; Gjertsen, Jan-Erik; Hallan, Geir; Dale, Håvard; Furnes, Ove Nord (Journal article; Peer reviewed, 2022)

  Background: Previous studies have suggested that the probability function of 1 minus the Kaplan-Meier survivorship overestimates revision rates of implants and that patient death should be included in estimates as a competing ...

• Buegangsdehiscens 

  Goplen, Frederik Kragerud; Hess-Erga, Jeanette; Opheim, Leif Runar; Silvola, Juha Tapio; Stene, Brit Kari; Törpel, Jörg; Uppheim, Alexander; Bunne, Bodil Iris Marie (Journal article; Peer reviewed, 2022)

  Buegangsdehiscens er en tilstand med plagsomme øresymptomer og svimmelhet forårsaket av en defekt i benet mellom det indre øret og midtre skallegrop. Sykdommen er ufarlig, og for mange pasienter er det tilstrekkelig med ...

• MicroRNA-138 abates fibroblast motility with effect on invasion of adjacent cancer cells 

  Rajthala, Saroj; Parajuli, Himalaya; Dongre, Harsh Nitin; Ljøkjel, Borghild; Hoven, Kristin Marie; Kvalheim, Arild; Lybak, Stein; Neppelberg, Evelyn; Sapkota, Dipak; Johannessen, Anne Christine; Costea, Daniela Elena (Journal article; Peer reviewed, 2022-03-17)

  Background: Recent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in CAFs in oral squamous cell carcinoma (OSCC) and its ...

• The nonlinearities in the galvanostatic charging curves of supercapacitors provide insights into charging mechanisms 

  Helseth, Lars Egil (Journal article; Peer reviewed, 2022)

  Supercapacitors are often charged using constant currents. The capacitance can be determined from the slope of the voltage-time curve if the measured voltage over the supercapacitor increases linearly with time. However, ...

• Early Evolutionary Selection of NAD Biosynthesis Pathway in Bacteria 

  Sharma, Suraj; Hsieh, Yin-Chen; Dietze, Jørn; Bockwoldt, Mathias; Strømland, Øyvind; Ziegler, Mathias; Heiland, Ines (Journal article; Peer reviewed, 2022)

  Bacteria use two alternative pathways to synthesize nicotinamide adenine dinucleotide (NAD) from nicotinamide (Nam). A short, two-step route proceeds through nicotinamide mononucleotide (NMN) formation, whereas the other ...

• Correlation between gene expression and MRI STIR signals in patients with chronic low back pain and Modic changes indicates immune involvement 

  Vigeland, Maria Dehli; Flåm, Siri Tennebø; Vigeland, Magnus Dehli; Espeland, Ansgar; Kristoffersen, Per Martin; Vetti, Nils; Wigemyr, Monica; Bråten, Lars Christian Haugli; Gjefsen, Elisabeth; Schistad, Ellina Iordanova; Haugen, Anne Julsrud; Johanessen, Anne Froholdt; Skouen, Jan Sture; Zwart, John Anker Henrik; Storheim, Kjersti; Pedersen, Linda Margareth; Lie, Benedicte Alexandra (Journal article; Peer reviewed, 2022-01-07)

  Disability and distress caused by chronic low back pain (LBP) lacking clear pathoanatomical explanations cause huge problems both for patients and society. A subgroup of patients has Modic changes (MC), identifiable by MRI ...

• Systematic reporting of medical kidney biopsies 

  Leh, Sabine; Dendooven, Amélie (Journal article; Peer reviewed, 2022)

  The medical kidney biopsy has an important added value in patient care in nephrology. In order to facilitate communication between the pathologist and the nephrologist and optimize patient care, both the content and form ...

• Enhancement of cranial nerves in Lyme neuroborreliosis: incidence and correlation with clinical symptoms and prognosis 

  Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Dareez, Muhammad Nazeer; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse Daasvand; Reiso, Harald; Lorentzen, Åslaug Rudjord; Harbo, Hanne; Beyer, Mona Kristiansen (Journal article; Peer reviewed, 2022)

  Purpose Symptoms of cranial neuritis are a common presentation of Lyme neuroborreliosis (LNB). Imaging studies are scarce and report contradictory low prevalence of enhancement compared to clinical studies of cranial ...

• Association of adverse childhood experiences with the development of multiple sclerosis 

  Eid, Karine; Torkildsen, Øivind; Aarseth, Jan Harald; Aalstad, Mari; Bhan, Alok; Celius, Elisabeth Gulowsen; Cortese, Marianna; Daltveit, Anne Kjersti Nesje; Holmøy, Trygve; Myhr, Kjell-Morten; Riise, Trond; Schuler, Stephan; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)

  Objective To study whether exposure to childhood emotional, sexual or physical abuse is associated with subsequent multiple sclerosis (MS) development. Methods A nationwide, prospective cohort study based on participants ...

• Changes in colonic enteroendocrine cells of patients with irritable bowel syndrome following fecal microbiota transplantation 

  Mazzawi, Tarek; Hausken, Trygve; El-Salhy, Magdy (Journal article; Peer reviewed, 2022)

  Objectives The aim was to investigate the effect of fecal microbiota transplantation (FMT) on colonic enteroendocrine cells densities in patients with irritable bowel syndrome (IBS). Materials and methods This study ...

• Lack of population genetic structure of lumpfish along the Norwegian coast: A reappraisal based on EST-STRs analyses 

  Jónsdóttir, Ólöf Dóra Bartels; Gíslason, Davíð; Ólafsdóttir, Guðbjörg; Maduna, Simo; Hagen, Snorre; Reynolds, Patrick; Sveinsson, Sæmundur; Imsland, Albert (Journal article; Peer reviewed, 2022)

  Lumpfish is now the single most important cleaner fish species to date and there is an extensive lumpfish translocation along the Norwegian coast. A reliable baseline information about the population genetic structure of ...

• Trends in Mortality Due to Myocardial Infarction, Stroke, and Pulmonary Embolism in Patients Receiving Dialysis 

  Ocak, Gurbey; Boenink, Rianne; Noordzij, Marlies; Bos, Willem Jan W.; Vikse, Bjørn Egil; Cases, Aleix; Kerschbaum, Julia; Helve, Jaakko; Nordio, Maurizio; Arici, Mustafa; Mercadal, Lucile; Wanner, Christoph; Palsson, Runolfur; Hommel, Kristine; De Meester, Johan; Kostopoulou, Myrto; Santamaria, Rafael; Rodrigo, Emilio; Rydell, Helena; Bell, Samira; Massy, Ziad A.; Jager, Kitty J.; Kramer, Anneke (Journal article; Peer reviewed, 2022)

  Importance: During the past decades, improvements in the prevention and management of myocardial infarction, stroke, and pulmonary embolism have led to a decline in cardiovascular mortality in the general population. ...

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