• Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia 

  Bruserud, Øystein; Reikvam, Håkon; Brenner, Annette (Journal article; Peer reviewed, 2022-01-23)

  Toll-like receptor 4 (TLR4) is a pattern-recognizing receptor that can bind exogenous and endogenous ligands. It is expressed by acute myeloid leukemia (AML) cells, several bone marrow stromal cells, and nonleukemic cells ...

• Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study 

  Pettersen, Trond Røed; Schjøtt, Jan Didrik; Allore, Heather G; Bendz, Bjørn; Borregaard, Britt; Fridlund, Bengt Gotthard Anton; Larsen, Alf Inge; Nordrehaug, Jan Erik; Rotevatn, Svein; Wentzel-Larsen, Tore; Norekvål, Tone Merete (Journal article; Peer reviewed, 2022)

  Objective: To determine patient perceptions of generic medicines 2 and 6 months after percutaneous coronary intervention (PCI), and to determine whether these perceptions moderate medication adherence. Design: Prospective ...

• The Association between Serum Serine and Glycine and Related-Metabolites with Pancreatic Cancer in a Prospective Cohort Study 

  Luu, Hung N.; Paragomi, Pedram; Wang, Renwei; Huang, Joyce Y.; Adams-Haduch, Jennifer; Midttun, Øivind; Ulvik, Arve; Nguyen, Tin C.; Brand, Randall E.; Gao, Yutang; Ueland, Per Magne; Yuan, Jian-Min (Journal article; Peer reviewed, 2022-04-28)

  Background: Serine and glycine play an important role in the folate-dependent one-carbon metabolism. The metabolism of serine and glycine has been shown to be associated with cancer cell proliferation. No prior epidemiologic ...

• Put your weight behind it—Effect of body mass index on the active second stage of labour: A retrospective cohort study 

  Østborg, Tilde Broch; Sande, Ragnar; Kessler, Jørg; Tappert, Christian; Von, Brandis Philip; Eggebø, Torbjørn Moe (Journal article; Peer reviewed, 2022)

  Objective: To explore the duration of the active phase of the second stage of labour in relation to maternal pre-pregnant body mass index (BMI). Design: Retrospective cohort study. Setting: Labour wards of three ...

• CA-125 levels are predictive of survival in low-grade serous ovarian cancer—A multicenter analysis 

  Wohlmuth, Christoph; Djedovic, Vladimir; Kjær, Susanne K.; Jensen, Allan; Glasspool, Rosalind; Roxburgh, Patricia; Defazio, Anna; Johnatty, Sharon E.; Webb, Penelope M.; Modugno, Francesmary; Lambrechts, Diether; Schildkraut, Joellen M.; Berchuck, Andrew; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Høgdall, Estrid; Høgdall, Claus K.; Goode, Ellen L.; Winham, Stacey J.; Matsuo, Keitaro; Karlan, Beth Y.; Lester, Jenny; Goodman, Marc T.; Thompson, Pamela J.; Pejovic, Tanja; Riggan, Marjorie J.; Lajkosz, Katherine; Tone, Alicia; May, Taymaa (Journal article; Peer reviewed, 2022-04-13)

  Objective: Studies on low-grade serous ovarian cancer (LGSC) are limited by a low number of cases. The aim of this study was to define the prognostic significance of age, stage, and CA-125 levels on survival in a ...

• Book Review: The Law of the Sea, by Robin Churchill, Vaughan Lowe, and Amy Sander 

  Siekiera, Joanna (Journal article; Peer reviewed, 2022)

• Potential and limitation of 230Th-excess as a chronostratigraphic tool for late Quaternary Arctic Ocean sediment studies: An example from the Southern Lomonosov Ridge 

  Purcell, Karl Guy Romeo; Hillaire-Marcel, Claude; de Vernal, Anne; Ghaleb, Bassam; Stein, Ruediger (Journal article; Peer reviewed, 2022)

  Recently, the use of “extinction ages” of excesses in U-series isotopes (230Thxs, 231Paxs) has been proposed for the setting of benchmark ages of up to ~350 and ~150 ka, respectively, in late Quaternary marine records from ...

• Cortical thickness changes after computerized working memory training in patients with mild cognitive impairment 

  Hol, Haakon Ramsland; Flak, Marianne Møretrø; Chang, Linda; Løhaugen, Gro; Bjuland, Knut Jørgen; Rimol, Lars Morten; Engvig, Andreas; Skranes, Jon Sverre; Ernst, Thomas; Madsen, Bengt-Ove; Hernes, Susanne M S (Journal article; Peer reviewed, 2022-04-04)

  Background: Adaptive computerized working memory (WM) training has shown favorable effects on cerebral cortical thickness as compared to non-adaptive training in healthy individuals. However, knowledge of WM training-related ...

• Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain 

  Holmgren, Asbjørn; Hansson, Lars; Bjerkaas-Kjeldal, Kristine; Impellizzeri, Agata Antonia Rita; Gilfillan, Gregor; Djurovic, Srdjan; Hughes, Timothy (Journal article; Peer reviewed, 2022)

  The gene ankyrin-3 (ANK3) has been consistently associated with bipolar disorder (BD) in several genome-wide association studies (GWAS). The exact molecular mechanisms underlying this genetic association remain unknown. ...

• Training a supermodel with noisy and sparse observations: A case study with CPT and the synch rule on SPEEDO-v.1 

  Schevenhoven, Francine Janneke; Carrassi, Alberto (Journal article; Peer reviewed, 2022)

  As an alternative to using the standard multi-model ensemble (MME) approach to combine the output of different models to improve prediction skill, models can also be combined dynamically to form a so-called supermodel. The ...

• A Novel Prophylaxis Strategy Using Liposomal Vaccine Adjuvant CAF09b Protects against Influenza Virus Disease 

  Zimmermann, Julie; Schmidt, Signe Tandrup; Trebbien, Ramona; Cox, Rebecca Jane; Zhou, Fan; Follmann, Frank; Pedersen, Gabriel Kristian; Christensen, Dennis (Journal article; Peer reviewed, 2022-02-06)

  The SARS-CoV-2 pandemic caused a massive health and societal crisis, although the fast development of effective vaccines reduced some of the impact. To prepare for future respiratory virus pandemics, a pan-viral prophylaxis ...

• Prenatal dexamethasone treatment for classic 21-hydroxylase deficiency in Europe 

  Nowotny, Hanna; Neumann, Uta; Tardy-Guidollet, Veronique; Faisal Ahmed, Ahmed; Baronio, Federico; Battelino, Tadej; Bertherat, Jerome; Blankenstein, Oliver; Bonomi, Marco; Bouvattier, Claire; De la Perrière, Aude Brac; Brucker, Sara; Cappa, Marco; Chanson, Philippe; Van der Grinten, Hedi L. Claahsen; Colao, Annamaria; Cools, Martine; Davies, Justin H.; Dorr, Helmut-Gunther; Fenske, Wiebke K.; Ghigo, Ezio; Giordano, Roberta; Gravholt, Claus H.; Huebner, Angela; Husebye, Eystein Sverre; Igbokwe, Rebecca; Juul, Anders; Kiefer, Florian W.; Leger, Juliane; Menassa, Rita; Meyer, Gesine; Neocleous, Vassos; Phylactou, Leonidas A.; Rohayem, Julia; Russo, Gianni; Scaroni, Carla; Touraine, Philippe; Unger, Nicole; Vojtkova, Jarmila; Yeste, Diego; Lajic, Svetlana; Reisch, Nicole (Journal article; Peer reviewed, 2022)

  Objective: To assess the current medical practice in Europe regarding prenatal dexamethasone (Pdex) treatment of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. Design and methods: A questionnaire ...

• Factors associated with coronary heart disease in COPD patients and controls 

  Svendsen, Christina D.; Kuiper, Karel Kier-Jan; Ostridge, Kristoffer; Larsen, Terje Hjalmar; Nielsen, Rune; Hodneland, Vidar; Nordeide, Eli; Bakke, Per S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2022-04-27)

  Background: COPD and coronary heart disease (CHD) frequently co-occur, yet which COPD phenotypes are most prone to CHD is poorly understood. The aim of this study was to see whether COPD patients did have a true higher ...

• Dansgaard-Oeschger and Heinrich event temperature anomalies in the North Atlantic set by sea ice, frontal position and thermocline structure 

  Pedro, J.B.; Andersson, Carin; Vettoretti, G.; Voelker, A.H.L.; Waelbroeck, C.; Dokken, Trond Martin; Jensen, Mari Fjalstad; Rasmussen, S.O.; Sessford, Evangeline; Jochum, M.; Nisancioglu, Kerim Hestnes (Journal article; Peer reviewed, 2022)

  We use eighteen timescale-synchronised near-surface temperature reconstructions spanning 10–50 thousand years before present to clarify the regional expression of Dansgaard-Oeschger (D-O) and Heinrich (H) events in the ...

• Safety and Clinical Efficacy of Mesenchymal Stem Cell Treatment in Traumatic Spinal Cord Injury, Multiple Sclerosis and Ischemic Stroke – A Systematic Review and Meta-Analysis 

  Kvistad, Christopher Elnan; Kråkenes, Torbjørn; Gjengedal, Gudveig Cecilie Gjerde; Mustafa, Kamal Babikeir Elnour; Rekand, Tiina; Bø, Lars (Journal article; Peer reviewed, 2022-05-30)

  Background: Mesenchymal stem cells (MSCs) is an attractive candidate in regenerative research and clinical trials have assessed their therapeutic potential in different neurological conditions with disparate etiologies. ...

• Minimal important change was on the lower spectrum of previous estimates and responsiveness was sufficient for core outcomes in chronic low back pain 

  Bråten, Lars Christian Haugli; Grøvle, Lars; Wigemyr, Monica; Wilhelmsen, Maja; Gjefsen, Elisabeth; Espeland, Ansgar; Haugen, Anne Julsrud; Skouen, Jan Sture; Brox, Jens Ivar; Zwart, John Anker Henrik; Storheim, Kjersti; Ostelo, Raymond WJG.; Grotle, Margreth (Journal article; Peer reviewed, 2022)

  Objectives: The objective of this study was to estimate the minimal important change (MIC) and responsiveness of core patient reported outcome measures for chronic low back pain (LBP) and Modic changes. Study Design and ...

• Acute kidney injury in patients with COVID-19 in the intensive care unit: Evaluation of risk factors and mortality in a national cohort 

  Aukland, Eirik Aasen; Klepstad, Pål; Aukland, Stein Magnus; Zamanzad Ghavidel, Fatemeh; Buanes, Eirik Alnes (Journal article; Peer reviewed, 2022)

  Objectives: Acute kidney injury (AKI) is a frequent complication among critical ill patients with COVID-19, but the actual incidence is unknown as AKI-incidence varies from 25% to 89% in intensive care unit (ICU) populations. ...

• Mathematical modelling of follicular growth and ovarian stimulation 

  Fischer-Holzhausen, Sophie; Röblitz, Susanna (Journal article; Peer reviewed, 2022)

  The aim of ovarian stimulation in fertility treatment is to increase the number of large follicles and hence the number of eggs that can be retrieved for in vitro fertilisation (IVF). However, large inter- and intra-individual ...

• Etiske dilemmaer for sykehjemsleger under covid-19-pandemien 

  Mclean, Emily; Onarheim, Kristine Husøy; Schanche, Elisabeth; Schaufel, Margrethe Aase; Miljeteig, Ingrid (Journal article; Peer reviewed, 2022)

  Bakgrunn: Sykehjemsbeboere var ekstra sårbare for et alvorlig forløp av covid-19. Tidlig i pandemien ble det derfor bestemt at sykehjemmene måtte beskyttes gjennom tiltak som besøksforbud og testing- og isolasjonsregimer. ...

• European Society of Paediatric Radiology Artificial Intelligence taskforce: a new taskforce for the digital age 

  Laborie, Lene Bjerke; Naidoo, Jaishree; Pace, Erika; Ciet, Pierluigi; Eade, Christine; Wagner, Matthias W.; Huisman, Thierry A. G. M.; Shelmerdine, Susan C. (Journal article; Peer reviewed, 2022)

  A new task force dedicated to artificial intelligence (AI) with respect to paediatric radiology was created in 2021 at the International Paediatric Radiology (IPR) meeting in Rome, Italy (a joint society meeting by the ...

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