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    • Genome- and transcriptomederived microsatellite loci in lumpfsh Cyclopterus lumpus: molecular tools for aquaculture, conservation and fsheries management 

      Maduna, Simo; Vivian-Smith, Adam; Jónsdóttir, Ólöf Dóra Bartels; Imsland, Albert; Klutsch, Cornelya; Nyman, Tommi; Eiken, Hans Geir; Hagen, Snorre (Journal article; Peer reviewed, 2020)
      The lumpfish Cyclopterus lumpus is commercially exploited in numerous areas of its range in the North Atlantic Ocean, and is important in salmonid aquaculture as a biological agent for controlling sea lice. Despite the ...

    • Genome-wide analyses of vocabulary size in infancy and toddlerhood: associations with ADHD, literacy and cognition-related traits 

      Verhoef, Ellen; Allegrini, Andrea G.; Jansen, Philip R.; Lange, Katherine; Wang, Carol A.; Morgan, Angela; Ahluwalia, Tarunveer S.; Symeonides, Christos; Eising, Else; Franken, Marie-Christine; Hypponen, Elina; Mansell, Toby; Olislagers, Mitchell; Omerovic, Emina; Rimfeld, Kaili; Schlag, Fenja; Selzam, Saskia; Shapland, Chin Yang; Tiemeier, Henning; Whitehouse, Andrew J.O.; Saffery, Richard; Bønnelykke, Klaus; Reilly, Sheena; Pennell, Craig E.; Wake, Melissa; Cecil, Charlotte A. M.; Plomin, Robert; Fisher, Simon E.; St Pourcain, Beate; Andreassen, Ole; Bartels, Meike; Boomsma, Dorret; Dale, Philip S.; Ehli, Erik; Fernandez-Orth, Dietmar; Guxens, Mònica; Hakulinen, Christian; Harris, Kathleen Mullan; Haworth, Simon; de Hoyos, Lucía; Jaddoe, Vincent; Keltikangas-Järvinen, Liisa; Lehtimäki, Terho; Middeldorp, Christel; Min, Josine L.; Mishra, Pashupati P.; Njølstad, Pål Rasmus; Sunyer, Jordi; Tate, Ashley E.; Timpson, Nicholas; van der Laan, Camiel; Vrijheid, Martine; Vuoksimaa, Eero; Whipp, Alyce M.; Ystrøm, Eivind (Journal article; Peer reviewed, 2024)
      Background The number of words children produce (expressive vocabulary) and understand (receptive vocabulary) changes rapidly during early development, partially due to genetic factors. Here, we performed a meta–genome-wide ...

    • Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression 

      Holen, Børge; Shadrin, Alexey; Icick, Romain; Filiz, Tahir Tekin; Hindley, Guy Frederick Lanyon; Rødevand, Linn; O'Connell, Kevin Sean; Hagen, Espen; Frei, Oleksandr; Bahrami, Shahram; Cheng, Weiqiu; Parker, Nadine; Woldeyohannes, Markos Tesfaye; Jaholkowski, Piotr Pawel; Karadag, Naz; Dale, Anders M; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Journal article; Peer reviewed, 2023)
      Opioid use disorder (OUD) and mental disorders are often comorbid, with increased morbidity and mortality. The causes underlying this relationship are poorly understood. Although these conditions are highly heritable, their ...

    • Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability 

      Holen, Børge; Kutrolli, Gleda; Shadrin, Alexey; Icick, Romain; Hindley, Guy; Rødevand, Linn; O'Connell, Kevin Sean; Frei, Oleksandr; Parker, Nadine; Tesfaye, Markos; Deak, Joseph D.; Jaholkowski, Piotr Pawel; Dale, Anders M.; Djurovic, Srdjan; Andreassen, Ole; Smeland, Olav Bjerkehagen (Journal article; Peer reviewed, 2023)
      Background Opioid use disorder (OUD), a serious health burden worldwide, is associated with lower cognitive function. Recent studies have demonstrated a negative genetic correlation between OUD and general cognitive ...

    • Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa 

      Bang, Lasse; Bahrami, Shahram; Hindley, Guy; Smeland, Olav Bjerkehagen; Rødevand, Linn; Jaholkowski, Piotr Pawel; Shadrin, Alexey; O'Connell, Kevin Sean; Frei, Oleksandr; Lin, Aihua; Rahman, Zillur; Cheng, Weiqiu; Parker, Nadine; Fan, Chun C.; Dale, Anders M.; Djurovic, Srdjan; Bulik, Cynthia M.; Andreassen, Ole (Journal article; Peer reviewed, 2023)
      Anorexia nervosa (AN) is a heritable eating disorder (50–60%) with an array of commonly comorbid psychiatric disorders and related traits. Although significant genetic correlations between AN and psychiatric disorders and ...

    • Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci 

      Wiström, Erik David; O'Connell, Kevin Sean; Karadag, Naz; Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Lin, Aihua; Cheng, Weiqiu; Steen, Nils Eiel; Shadrin, Alexey; Frei, Oleksandr; Djurovic, Srdjan; Dale, Anders M.; Andreassen, Ole A.; Smeland, Olav Bjerkehagen (Journal article; Peer reviewed, 2022)
      Background and aim Schizophrenia (SCZ) and bipolar disorder (BD) have a high comorbidity of alcohol use disorder (AUD), and both comorbid AUD and excessive alcohol consumption (AC) have been linked to greater illness ...

    • Genome-wide Association Analysis of Parkinson’s Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci 

      Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Bahrami, Shahram; Broce, Iris J.; Tesli, Martin Steen; Frei, Oleksandr; Wirgenes, Katrine Verena; O`Connell, Kevin; Krull, Florian; Bettella, Francesco; Steen, Nils Eiel; Sugrue, Leo P.; Wang, Yunpeng; Svenningsson, Per; Sharma, Manu; Pihlstrøm, Lasse; Toft, H. Mathias S.; O’Donovan, Michael; Djurovic, Srdjan; Desikan, Rahul S; Dale, Anders M.; Andreassen, Ole Andreas (Journal article; Peer reviewed, 2021)
      Background Parkinson’s disease (PD) and schizophrenia (SCZ) are heritable brain disorders that involve dysregulation of the dopaminergic system. Epidemiological studies have reported potential comorbidity between the ...

    • Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci 

      Jaholkowski, Piotr Pawel; Hindley, Guy; Shadrin, Alexey; Tesfaye, Markos; Bahrami, Shahram; Nerhus, Mari; Rahman, Zillur; O'Connell, Kevin Sean; Holen, Børge; Parker, Nadine; Cheng, Weiqiu; Lin, Aihua; Rødevand, Linn; Karadag, Naz; Frei, Oleksandr; Djurovic, Srdjan; Dale, Anders M.; Smeland, Olav Bjerkehagen; Andreassen, Ole (Journal article; Peer reviewed, 2023)
      Low vitamin D (vitD) levels have been consistently reported in schizophrenia (SCZ) suggesting a role in the etiopathology. However, little is known about the role of underlying shared genetic mechanisms. We applied a ...

    • Genome-wide association meta-analysis of childhood and adolescent internalizing symptoms 

      Jami, Eshim S.; Hammerschlag, Anke R.; Ip, Hill F.; Allegrini, Andrea G.; Benyamin, Beben; Border, Richard; Diemer, Elizabeth W.; Jiang, Chang; Karhunen, Ville; Lu, Yi; Lu, Qing; Mallard, Travis T.; Mishra, Pashupati P.; Nolte, Ilja M.; Palviainen, Teemu; Peterson, Roseann E.; Sallis, Hannah M.; Shabalin, Andrey A.; Tate, Ashley E.; Thiering, Elisabeth; Vilor-Tejedor, Natàlia; Wang, Carol; Zhou, Ang; Adkins, Daniel E.; Alemany, Silvia; Ask, Helga; Chen, Qi; Corley, Robin P.; Ehli, Erik A.; Evans, Luke M.; Havdahl, Alexandra; Hagenbeek, Fiona A.; Hakulinen, Christian; Henders, Anjali K.; Hottenga, Jouke Jan; Korhonen, Tellervo; Mamun, Abdullah; Marrington, Shelby; Neumann, Alexander; Rimfeld, Kaili; Rivadeneira, Fernando; Silberg, Judy L.; van Beijsterveldt, Catharina E.; Vuoksimaa, Eero; Whipp, Alyce M.; Tong, Xiaoran; Andreassen, Ole; Boomsma, Dorret I.; Brown, Sandra A.; Burt, S. Alexandra; Copeland, William; Dick, Danielle M.; Harden, K. Paige; Harris, Kathleen Mullan; Hartman, Catharina A.; Heinrich, Joachim; Hewitt, John K.; Hopfer, Christian; Hypponen, Elina; Jarvelin, Marjo-Riitta; Kaprio, Jaakko; Keltikangas-Järvinen, Liisa; Klump, Kelly L.; Krauter, Kenneth; Kuja-Halkola, Ralf; Larsson, Henrik; Lehtimäki, Terho; Lichtenstein, Paul; Lundström, Sebastian; Maes, Hermine H.; Magnus, Per Minor; Munafò, Marcus R.; Najman, Jake M.; Njølstad, Pål Rasmus; Oldehinkel, Albertine J.; Pennell, Craig E.; Plomin, Robert; Reichborn-Kjennerud, Ted; Reynolds, Chandra; Rose, Richard J.; Smolen, Andrew; Snieder, Harold; Stallings, Michael; Standl, Marie; Sunyer, Jordi; Tiemeier, Henning; Wadsworth, Sally J.; Wall, Tamara L.; Whitehouse, Andrew J.O.; Williams, Gail M.; Ystrøm, Eivind; Nivard, Michel G.; Bartels, Meike; Middeldorp, Christel M. (Journal article; Peer reviewed, 2022)
      Objective: To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. Method: In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated ...

    • Genome-wide association study identifies 30 loci associated with bipolar disorder 

      Stahl, Eli A.; Breen, Gerome; Forstner, Andreas J.; McQuillin, Andrew; Ripke, Stephan; Trubetskoy, Vassily; Mattheisen, Manuel; Wang, Yunpeng; Coleman, Jonathan R.I.; Gaspar, Héléna A.; de Leeuw, Christiaan A.; Steinberg, Stacy; Pavlides, Jennifer M. Whitehead; Trzaskowski, Maciej; Byrne, Enda M.; Pers, Tune H.; Holmans, Peter A.; Richards, Alexander L.; Abbott, Liam; Agerbo, Esben; Akil, Huda; Albani, Diego; Alliey-Rodriguez, Ney; Als, Thomas D.; Anjorin, Adebayo; Antilla, Verneri; Awasthi, Swapnil; Badner, Judith A.; Bækvad-Hansen, Marie; Barchas, Jack D.; Bass, Nicholas; Bauer, Michael; Belliveau, Richard; Bergen, Sarah E.; Pedersen, Carsten Bøcker; Bøen, Erlend; Boks, Marco P.; Boocock, James; Budde, Monika; Bunney, William; Burmeister, Margit; Bybjerg-Grauholm, Jonas; Byerley, William; Casas, Miquel; Cerrato, Felecia; Cervantes, Pablo; Chambert, Kimberly; Charney, Alxander W.; Chen, Danfeng; Churchhouse, Claire; Clarke, Toni-Kim; Coryell, William; Craig, David W.; Cruceanu, Cristiana; Curtis, David; Czerski, Piotr M.; Dale, Anders; de Jong, Simone; Degenhardt, Franziska; Del-Favero, Jurgen; Depaulo, J. Raymond; Djurovic, Srdjan; Dobbyn, Amanda L.; Dumont, Ashley; Elvsåshagen, Torbjørn; Escott-Price, Valentina; Fan, Chun Chieh; Fischer, Sascha B.; Flickinger, Matthew; Foroud, Tatiana M.; Forty, Liz; Frank, Josef; Fraser, Christine; Freimer, Nelson B.; Frisén, Louise; Gade, Katrin; Gage, Diane; Garnham, Julie; Giambartolomei, Claudia; Pedersen, Marianne Giørtz; Goldstein, Jaqueline; Gordon, Scott D.; Gordon-Smith, Katherine; Green, Elaine K.; Green, Melissa J.; Greenwood, Tifany A.; Grove, Jakob; Guan, Weihua; Guzman-Parra, José; Hamshere, Marian L.; Hautzinger, Martin; Heilbronner, Urs; Herms, Stefan; Hipolito, Maria; Hoffmann, Per; Holland, Dominic; Huckins, Laura; Jamain, Stéphane; Johnson, Jessica S.; Juréus, Anders; Kandaswamy, Radhika; Karlsson, Robert; Kennedy, James L.; Kittel-Schneider, Sarah; Knowles, James A.; Kogevinas, Manolis; Koller, Anna C.; Kupka, Ralph; Lavebratt, Catharina; Lawrence, Jacob; Lawson, William B.; Leber, Markus; Lee, Phil H.; Levy, Shawn E.; Li, Jun Z.; Liu, Chunyu; Lucae, Susanne; Maaser, Anna; MacIntyre, Donald J.; Mahon, Pamela B.; Maier, Wolfgang; Martinsson, Lina; McCarroll, Steve; McGuffin, Peter; McInnis, Melvin G.; McKay, James D.; Medeiros, Helena; Medland, Sarah E.; Meng, Fan; Milani, Lili; Montgomery, Grant W.; Morris, Derek W.; Mühleisen, Thomas W.; Mullins, Niamh; Nguyen, Hoang; Nievergelt, Caroline M.; Adolfsson, Annelie Nordin; Nwulia, Evaristus A.; O'Donovan, Claire; Loohuis, Loes M. Olde; Ori, Anil P.S.; Oruc, Lilijana; Ösby, Urban; Perlis, Roy H.; Perry, Amy; Pfennig, Andrea; Potash, James B.; Purcell, Shaun M.; Regeer, Eline J.; Reif, Andreas; Reinbold, Céline S.; Rice, John P.; Rivas, Fabio; Rivera, Margarita; Roussos, Panos; Ruderfer, Douglas M.; Ryu, Euijung; Sánchez-Mora, Cristina; Schatzberg, Alan F.; Scheftner, William A.; Schork, Nicholas J.; Shannon Weickert, Cynthia; Shehktman, Tatyana; Shilling, Paul D.; Sigurdsson, Engilbert; Slaney, Claire; Smeland, Olav Bjerkehagen; Sobell, Janet L.; Søholm Hansen, Christine; Spijker, Anne T.; St Clair, David; Steffens, Michael; Strauss, John S.; Streit, Fabian; Strohmaier, Jana; Szelinger, Szabolcs; Thompson, Robert C.; Thorgeirsson, Thorgeir E; Treutlein, Jens; Vedder, Helmut; Wang, Weiqing; Watson, Stanley J.; Weickert, Thomas W.; Witt, Stephanie H.; Xi, Simon; Xu, Wei; Young, Allan H.; Zandi, Peter; Zhang, Peng; Zöllner, Sebastian; Adolfsson, Rolf; Agartz, Ingrid; Alda, Martin; Backlund, Lena; Baune, Bernhard T.; Bellivier, Frank; Berrettini, Wade H.; Biernacka, Joanna M.; Blackwood, Douglas H.R.; Boehnke, Michael; Børglum, Anders D.; Corvin, Aiden; Craddock, Nicholas; Daly, Mark J.; Dannlowski, Udo; Esko, Tõnu; Etain, Bruno; Frye, Mark; Fullerton, Janice M.; Gershon, Elliot S.; Gill, Michael; Goes, Fernando; Grigoroiu-Serbanescu, Maria; Hauser, Joanna; Hougaard, David M.; Hultman, Christina M.; Jones, Ian; Jones, Lisa A.; Kahn, René S.; Kirov, George; Landén, Mikael; Leboyer, Marion; Lewis, Cathryn M.; Li, Qingqin S.; Lissowska, Jolanta; Martin, Nicholas G.; Mayoral, Fermin; McElroy, Susan L.; McIntosh, Andrew M.; McMahon, Francis J.; Melle, Ingrid; Metspalu, Andres; Mitchell, Philip B.; Morken, Gunnar; Mors, Ole; Mortensen, Preben Bo; Müller-Myhsok, Bertram; Myers, Richard M.; Neale, Benjamin M.; Nimgaonkar, Vishwajit; Nordentoft, Merete; Nöthen, Markus M.; O'Donovan, Michael C; Ødegaard, Ketil Joachim; Owen, Michael J.; Paciga, Sara A.; Pato, Carlos; Pato, Michele T.; Posthuma, Danielle; Ramos-Quiroga, Josep Antoni; Ribasés, Marta; Rietschel, Marcella; Rouleau, Guy A.; Schalling, Martin; Schofield, Peter R.; Schulze, Thomas G.; Serretti, Alessandro; Smoller, Jordan W.; Stefansson, Hreinn; Stefansson, Kari; Stordal, Eystein; Sullivan, Patrick F.; Turecki, Gustavo; Vaaler, Arne; Vieta, Eduard; Vincent, John B.; Werge, Thomas; Nurnberger, John I.; Wray, Naomi R.; Di Florio, Arianna; Edenberg, Howard J.; Cichon, Sven; Ophoff, Roel A.; Scott, Laura J.; Andreassen, Ole Andreas; Kelsoe, John; Sklar, Pamela (Journal article; Peer reviewed, 2019)
      Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with ...

    • Genome-wide association study identifies Sjögren’s risk loci with functional implications in immune and glandular cells 

      Khatri, Bhuwan; Tessneer, Kandice L.; Rasmussen, Astrid; Aghakhanian, Farhang; Reksten, Tove Ragna; Adler, Adam; Alevizos, Ilias; Anaya, Juan-Manuel; Aqrawi, Lara A.; Baecklund, Eva; Brun, Johan Gorgas; Bucher, Sara Magnusson; Eloranta, Maija-Leena; Engelke, Fiona; Forsblad-d’Elia, Helena; Glenn, Stuart B.; Hammenfors, Daniel; Imgenberg-Kreuz, Juliana; Jensen, Janicke Liaaen; Johnsen, Svein Joar Auglæn; Jonsson, Malin Viktoria; Kvarnström, Marika; Kelly, Jennifer A.; Li, He; Mandl, Thomas; Martín, Javier; Nocturne, Gaétane; Norheim, Katrine Brække; Palm, Øyvind; Skarstein, Kathrine; Stolarczyk, Anna M.; Taylor, Kimberly E.; Teruel, Maria; Theander, Elke; Venuturupalli, Swamy; Wallace, Daniel J.; Grundahl, Kiely M.; Hefner, Kimberly S.; Radfar, Lida; Lewis, David M.; Stone, Donald U.; Kaufman, C. Erick; Brennan, Michael T.; Guthridge, Joel M.; James, Judith A.; Scofield, R. Hal; Gaffney, Patrick M.; Criswell, Lindsey A.; Jonsson, Roland; Eriksson, Per; Bowman, Simon J.; Omdal, Roald; Rönnblom, Lars; Warner, Blake; Rischmueller, Maureen; Witte, Torsten; Farris, A. Darise; Mariette, Xavier; Alarcon-Riquelme, Marta E.; Shiboski, Caroline H.; Herlenius, Marie Elisabeth Wahren; Ng, Wan-Fai; Sivils, Kathy L.; Adrianto, Indra; Nordmark, Gunnel; Lessard, Christopher J. (Journal article; Peer reviewed, 2022)
      Sjögren’s disease is a complex autoimmune disease with twelve established susceptibility loci. This genome-wide association study (GWAS) identifies ten novel genome-wide significant (GWS) regions in Sjögren’s cases of ...

    • A genome-wide association study of bronchodilator response in participants of European and African ancestry from six independent cohorts 

      Gereige, Jessica D.; Xu, Hanfei; Ortega, Victor E.; Cho, Michael H.; Liu, Ming; Sakornsakolpat, Phuwanat; Silverman, Edwin K.; Beaty, Terri H.; Miller, Bruce E.; Bakke, Per S.; Gulsvik, Amund; Hersh, Craig P.; Morrow, Jarrett D.; Ampleford, Elizabeth J.; Hawkins, Gregory A.; Bleecker, Eugene R.; Meyers, Deborah A.; Peters, Stephen P.; Celedón, Juan C.; Tantisira, Kelan; Li, Jiang; Dupuis, Josée; O’connor, George T. (Journal article; Peer reviewed, 2022)
      Introduction Bronchodilator response (BDR) is a measurement of acute bronchodilation in response to short-acting β2-agonists, with a heritability between 10 and 40%. Identifying genetic variants associated with BDR may ...

    • Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain 

      Toker, Lilah; Tran, Gia T.; Sundaresan, Janani; Tysnes, Ole-Bjørn; Alves, Guido; Haugarvoll, Kristoffer; Nido, Gonzalo S.; Dölle, Christian; Tzoulis, Charalampos (Journal article; Peer reviewed, 2021)
      Background: Parkinson’s disease (PD) is a complex, age-related neurodegenerative disorder of largely unknown etiology. PD is strongly associated with mitochondrial respiratory dysfunction, which can lead to epigenetic ...

    • Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers 

      Jansen, Iris E.; van der Lee, Sven J.; Gomez-Fonseca, Duber; de Rojas, Itziar; Dalmasso, Maria Carolina; Grenier-Boley, Benjamin; Athanasiu, Lavinia; Bahrami, Shahram; Bergh, Sverre; Djurovic, Srdjan; Fladby, Tormod; Jarholm, Jonas Alexander; Knapskog, Anne Brita; Pålhaugen, Lene; Saltvedt, Ingvild; Selbæk, Geir; Selnes, Per; Andreassen, Ole; Shadrin, Alexey; Skoog, Ingmar; Soininen, Hilkka; Tsolaki, Magda; Van Broeckhoven, Christine; Van Dongen, Jasper; van Swieten, John C.; Vandenberghe, Rik; Vidal, Jean-Sébastien; Visser, Pieter J.; Vogelgsang, Jonathan; Waern, Margda; Wagner, Michael; Wiltfang, Jens; Wittens, Mandy M.J.; Zetterberg, Henrik; Zulaica, Miren; van Duijn, Cornelia M.; Bjerke, Maria; Engelborghs, Sebastiaan; Jessen, Frank; Teunissen, Charlotte E.; Pastor, Pau; Hiltunen, Mikko; Ingelsson, Martin; Clarimón, Jordi; Sleegers, Kristel; Ruiz, Agustín; Ramirez, Alfredo; Cruchaga, Carlos; Lambert, Jean-Charles; van der Flier, Wiesje M. (Journal article; Peer reviewed, 2022)
      Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer’s disease (AD) more directly than clinical diagnosis. Initiated by the European ...

    • Genomes of Thaumarchaeota from deep sea sediments reveal specific adaptations of three independently evolved lineages 

      Kerou, Melina; Ponce-Toledo, Rafael I.; Zhao, Rui; Abby, Sophie S.; Hirai, Miho; Nomaki, Hidetaka; Takaki, Yoshihiro; Nunoura, Takuro; Jørgensen, Steffen Leth; Schleper, Christa (Journal article; Peer reviewed, 2021)
      Marine sediments represent a vast habitat for complex microbiomes. Among these, ammonia oxidizing archaea (AOA) of the phylum Thaumarchaeota are one of the most common, yet little explored, inhabitants, which seem ...

    • Genomic Adaptations to an Endoparasitic Lifestyle in the Morphologically Atypical Crustacean Sacculina carcini (Cirripedia: Rhizocephala) 

      Martin, Sebastian; Lesny, Peter; Glenner, Henrik; Hecht, Jochen; Vilcinskas, Andreas; Bartolomaeus, Thomas; Podsiadlowski, Lars (Journal article; Peer reviewed, 2022)
      The endoparasitic crustacean Sacculina carcini (Cirripedia: Rhizocephala) has a much simpler morphology than conventional filter-feeding barnacles, reflecting its parasitic lifestyle. To investigate the molecular basis of ...

    • Genomic alterations associated with mutational signatures, DNA damage repair and chromatin remodeling pathways in cervical carcinoma 

      Halle, Mari Kyllesø; Sundaresan, Aishwarya; Zhang, Jianqing; Pedamallu, Chandra S.; Srinivasasainagendra, Vinodh; Blair, Jessica; Brooke, Dewey; Bertelsen, Bjørn; Woie, Kathrine; Shrestha, Sadeep; Tiwari, Hemant K.; Wong, Yick Fu; Krakstad, Camilla; Ojesina, Akinyemi I (Journal article; Peer reviewed, 2021)
      Despite recent advances in the prevention of cervical cancer, the disease remains a leading cause of cancer-related deaths in women worldwide. By applying the GISTIC2.0 and/or the MutSig2CV algorithms on 430 whole-exome-sequenced ...

    • Genomic analysis of pasteurella atlantica provides insight on its virulence factors and phylogeny and highlights the potential of reverse vaccinology in aquaculture 

      Ellul, Rebecca Marie; Kalatzis, Panos G.; Frantzen, Cyril Alexander; Haugland, Gyri Teien; Gulla, Snorre; Colquhoun, Duncan John; Middelboe, Mathias; Wergeland, Heidrun Inger; Rønneseth, Anita (Journal article; Peer reviewed, 2021)
      Pasteurellosis in farmed lumpsuckers, Cyclopterus lumpus, has emerged as a serious disease in Norwegian aquaculture in recent years. Genomic characterization of the causative agent is essential in understanding the biology ...

    • Genomic analysis reveals neutral and adaptive patterns that challenge the current management regime for East Atlantic cod Gadus morhua L 

      Johansen, Torild; Besnier, Francois; Sanchez, Maria Quintela; Jorde, Per Erik; Glover, Kevin; Westgaard, Jon-Ivar; Dahle, Geir; Lien, Sigbjørn; Kent, Matthew Peter (Journal article; Peer reviewed, 2020)
      Challenging long‐held perceptions of fish management units can help to protect vulnerable stocks. When a fishery consisting of multiple genetic stocks is managed as a single unit, overexploitation and depletion of minor ...

    • Genomic characterization and therapeutic targeting of HPV undetected cervical carcinomas 

      Ruiz, Fiona J.; Sundaresan, Aishwarya; Zhang, Jin; Pedamallu, Chandra S.; Halle, Mari K.; Srinivasasainagendra, Vinodh; Zhang, Jianqing; Muhammad, Naoshad; Stanley, Jennifer; Markovina, Stephanie; Tiwari, Hemant K.; Grigsby, Perry W.; Krakstad, Camilla; Schwarz, Julie K.; Ojesina, Akinyemi I. (Journal article; Peer reviewed, 2021)
      Cervical cancer tumors with undetectable HPV (HPVU) have been underappreciated in clinical decision making. In this study, two independent CC datasets were used to characterize the largest cohort of HPVU tumors to date ...