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    • “I smile, but Without Showing My Teeth”: The Lived Experience of Cleft, Lip, and Palate in Adults 

      Moi, Asgjerd Litleré; Gjengedal, Harald; Lybak, Kari; Vindenes, Hallvard (Journal article; Peer reviewed, 2020)
      Objective: To explore and describe the experience of growing up with unilateral cleft lip and palate (CLP) in adults. Design: Face-to-face interviews. Giorgi’s phenomenological method was used for analysis. Parti ...

    • “I Turned to Things That Mean More to Me”: Unpacking the Activist Trajectories of Syrians in Oslo 

      Selim, Amany (Journal article; Peer reviewed, 2021)
      The article examines how Syrians’ activist trajectories have evolved in exile contexts of small Syrian communities and limited mobilization structures. Based on in-depth interviews with Syrians in Oslo, I argue that the ...

    • ‘I wanted to go, but they said wait’: Mothers’ bargaining power and strategies in careseeking for ill newborns in Ethiopia 

      Onarheim, Kristine Husøy; Moland, Karen Marie Ingeborg; Molla, Mitike; Miljeteig, Ingrid (Journal article; Peer reviewed, 2020)
      Introduction To prevent the 2.6 million newborn deaths occurring worldwide every year, health system improvements and changes in care-taker behaviour are necessary. Mothers are commonly assumed to be of particular importance ...

    • Ibadism and Law in Historical Contexts 

      Vikør, Knut S. (Journal article; Peer reviewed, 2020)
      Not Sunnis and not Shi’is, the Ibāḍī Muslims of Oman and some areas of North Africa form a “third branch” of Islam, with their own version of the Sharīʿa law. The development of this law displays many interconnections with ...

    • Ice-algal carbon supports harp and ringed seal diets in the European Arctic: evidence from fatty acid and stable isotope markers 

      Kunisch, Erin; Graeve, Martin; Gradinger, Rolf; Haug, Tore; Kovacs, Kit M.; Lydersen, Christian; Varpe, Øystein Heggernes; Bluhm, Bodil (Journal article; Peer reviewed, 2021)
      Sea-ice declines in the European Arctic have led to substantial changes in marine food webs. To better understand the biological implications of these changes, we quantified the contributions of ice-associated and pelagic ...

    • The Iceland-Faroe Slope Jet: a conduit for dense water toward the Faroe Bank Channel overflow 

      Semper, Stefanie; Pickart, Robert S.; Våge, Kjetil; Larsen, Karin Margretha H.; Hátún, Hjálmar; Hansen, Bogi (Journal article; Peer reviewed, 2020)
      Dense water from the Nordic Seas passes through the Faroe Bank Channel and supplies the lower limb of the Atlantic Meridional Overturning Circulation, a critical component of the climate system. Yet, the upstream pathways ...

    • Iconoclasm - A Road to Modernization? 

      Bagge, Sverre Håkon (Journal article; Peer reviewed, 2022)
      My point of departure is a conflict over images in the churches in Bergen, Norway in the 1560s, around 30 years after the Reformation. This introduced a brief period of iconoclasm in Denmark–Norway, inspired by Reformed ...

    • Identification and characterization of aptameric inhibitors of human neutrophil elastase 

      Malicki, Stanisław; Książek, Mirosław; Sochaj Gregorczyk, Alicja; Kaminska, Marta; Golda, Anna; Chruścicka, Barbara; Mizgalska, Danuta; Potempa, Jan; Marti, Hans Peter; Kozieł, Joanna; Wieczorek, Maciej; Pieczykolan, Jerzy; Mydel, Piotr Mateusz; Dubin, Grzegorz (Journal article; Peer reviewed, 2023)
      Human neutrophil elastase (HNE) plays a pivotal role in innate immunity, inflammation, and tissue remodeling. Aberrant proteolytic activity of HNE contributes to organ destruction in various chronic inflammatory diseases ...

    • Identification and characterization of the Atlantic salmon peptide transporter 1a 

      Gomes, Ana S.; Vacca, Francesca; Cinquetti, Raffaella; Murashita, Koji; Barca, Amilcare; Bossi, Elena; Rønnestad, Ivar; Verri, Tiziano (Journal article; Peer reviewed, 2020)
      Peptide transporter 1 (PepT1) mediates the uptake of dietary di-/tripeptides in vertebrates. However, in teleost fish gut, more than one PepT1-type transporter might operate, because of teleost-specific whole gen(om)e ...

    • Identification and characterization of two salmon louse heme peroxidases and their potential as vaccine antigens 

      Gislefoss, Elisabeth; Gamil, Amr Ahmed Abdelrahim; Øvergård, Aina-Cathrine; Evensen, Øystein (Journal article; Peer reviewed, 2023)
      Salmon louse, Lepeophtheirus salmonis, represents major challenge for salmon farming. Current treatments impose welfare issues and are costly, whereas prophylactic measures are unavailable. Two salmon louse heme peroxidases ...

    • Identification and functional characterization of a novel susceptibility locus for small vessel vasculitis with MPO-ANCA 

      Dahlqvist, Johanna; Ekman, Diana; Sennblad, Bengt; Kozyrev, Sergey V.; Nordin, Jessika; Karlsson, Åsa; Meadows, Jennifer R. S.; Hellbacher, Erik; Rantapää-Dahlqvist, Solbritt; Berglin, Ewa; Stegmayr, Bernd; Haslund, Bo; Palm, Øyvind; Haukeland, Hilde; Gunnarsson, Iva; Bruchfeld, Annette; Segelmark, Mårten; Ohlsson, Sophie; Mohammad, Aladdin J.; Svärd, Anna Jessica; Pullerits, Rille; Herlitz, Hans; Söderbergh, Annika; Pielberg, Gerli Rosengren; Rosenberg, Lina Hultin; Bianchi, Matteo; Muren, Eva; Omdal, Roald; Jonsson, Roland; Eloranta, Maija-Leena; Rönnblom, Lars; Söderkvist, Peter; Knight, Ann; Eriksson, Per; Lindblad-Toh, Kerstin (Journal article; Peer reviewed, 2021)
      Objective To identify and characterize genetic loci associated with the risk of developing ANCA-associated vasculitides (AAV). Methods Genetic association analyses were performed after Illumina sequencing of 1853 genes ...

    • Identification and genetic characterization of Saprolegnia parasitica, isolated from farmed and wild fish in Finland 

      Engblom, Christine; Landor, Lotta Anni Ingeborg; Sjöqvist, Conny; Korkea-aho, Tiina; Viljamaa-Dirks, Satu; Paulin, Lars; Wiklund, Tom (Journal article; Peer reviewed, 2023)
      Oomycete infections in farmed fish are one of the most significant disease issues in salmonid aquaculture worldwide. In the present study, Saprolegnia spp. in different farmed fish species in Finland were identified, and ...

    • Identification and quantification of valuable platform chemicals in aqueous product streams from a preliminary study of a large pilot-scale steam explosion of woody biomass using quantitative nuclear magnetic resonance spectroscopy 

      Ghoreishi, Solmaz; Løhre, Camilla; Hermundsgård, Dag Helge; Molnes, Joakim Lindgaard; Tanase-Opedal, Mihaela; Brusletto, Rune; Barth, Tanja (Journal article; Peer reviewed, 2022)
      Steam explosion breaks down the polymeric matrix and enables the recovery of valuable compounds from lignocellulosic feedstock. In the steam explosion process, biomass is treated with high-pressure steam which subsequently ...

    • Identification of a Blood-Based Protein Biomarker Panel for Lung Cancer Detection 

      El-Khoury, Victoria; Schritz, Anna; Kim, Sang-Yoon; Lesur, Antoine; Sertamo, Katriina; Bernardin, Francois; Petritis, Konstantinos; Pirrotte, Patrick; Selinsky, Cheryl; Whiteaker, Jeffrey R; Zhang, Haizhen; Kennedy, Jacob J; Lin, Chenwei; Lee, Lik Wee; Yan, Ping; Tran, Nhan L; Inge, Landon J; Chalabi, Khaled; Decker, Georges; Bjerkvig, Rolf; Paulovich, Amanda G; Berchem, Guy; Kim, Yeoun Jin (Journal article; Peer reviewed, 2020)
      Lung cancer is the deadliest cancer worldwide, mainly due to its advanced stage at the time of diagnosis. A non-invasive method for its early detection remains mandatory to improve patients’ survival. Plasma levels of 351 ...

    • Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes 

      Knutsen, Erik; Sajib, Saikat Das; Fiskaa, Tonje; Lorens, James Bradley; Gudjonsson, Thorarinn; Mælandsmo, Gunhild Mari; Johansen, Steinar Daae; Seternes, Ole Morten; Perander, Maria (Journal article; Peer reviewed, 2023)
      Epithelial-mesenchymal transition (EMT) is a cellular plasticity program critical for embryonic development and tissue regeneration, and aberrant EMT is associated with disease including cancer. The high degree of plasticity ...

    • Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients—a genome-wide association study adjusting for smoking habits 

      Smith, Robert Løvsletten; O’Connell, Kevin; Athanasiu, Lavinia; Djurovic, Srdjan; Kringen, Marianne K.; Andreassen, Ole Andreas; Molden, Espen (Journal article; Peer reviewed, 2020)
      Clozapine (CLZ) is the superior antipsychotic drug for treatment of schizophrenia, but exhibits an extensive interpatient pharmacokinetic variability. Here, we conducted a genome-wide association study (GWAS) of CLZ serum ...

    • Identification of a Phage Display-Derived Peptide Interacting with the N-Terminal Region of Factor VII Activating Protease (FSAP) Enables Characterization of Zymogen Activation 

      Berge-Seidl, Sebastian; Nielsen, Nis Valentin; Alfonso, Armando A Rodriguez; Etscheid, Michael; Kandanur, Sai Priya Sarma; Haug, Bengt Erik; Stensland, Maria; Thiede, Bernd; Karacan, M; Preising, N; Wiese, S; Standker, L; Declerck, Paul J.; Løset, Geir Åge; Kanse, Sandip (Journal article; Peer reviewed, 2022)
      Factor VII Activating protease (FSAP) has a protective effect in diverse disease conditions as inferred from studies in FSAP–/– mice and humans deficient in FSAP activity due to single-nucleotide polymorphism. The zymogen ...

    • Identification of biomarkers for glycaemic deterioration in type 2 diabetes 

      Slieker, Roderick C.; Donnelly, Louise A.; Akalestou, Elina; Lopez-Noriega, Livia; Melhem, Rana; Güneş, Ayşim; Abou Azar, Frederic; Efanov, Alexander; Georgiadou, Eleni; Muniangi-Muhitu, Hermine; Sheikh, Mahsa; Giordano, Giuseppe N.; Åkerlund, Mikael; Ahlqvist, Emma; Ali, Ashfaq; Banasik, Karina; Brunak, Søren; Barovic, Marko; Bouland, Gerard A.; Burdet, Frédéric; Canouil, Mickaël; Dragan, Iulian; Elders, Petra J. M.; Fernandez, Celine; Festa, Andreas; Fitipaldi, Hugo; Froguel, Phillippe; Gudmundsdottir, Valborg; Gudnason, Vilmundur; Gerl, Mathias J.; van der Heijden, Amber A.; Jennings, Lori L.; Hansen, Michael K.; Kim, Min; Leclerc, Isabelle; Klose, Christian; Kuznetsov, Dmitry; Mansour Aly, Dina; Mehl, Florence; Marek, Diana; Melander, Olle; Niknejad, Anne; Ottosson, Filip; Pavo, Imre; Duffin, Kevin; Syed, Samreen K.; Shaw, Janice L.; Cabrera, Over; Pullen, Timothy J.; Simons, Kai; Solimena, Michele; Suvitaival, Tommi; Wretlind, Asger; Rossing, Peter; Lyssenko, Valeriya; Legido Quigley, Cristina; Groop, Leif; Thorens, Bernard; Franks, Paul W.; Lim, Gareth E.; Estall, Jennifer; Ibberson, Mark; Beulens, Joline W. J.; ’t Hart, Leen M; Pearson, Ewan R.; Rutter, Guy A. (Journal article; Peer reviewed, 2023)
      We identify biomarkers for disease progression in three type 2 diabetes cohorts encompassing 2,973 individuals across three molecular classes, metabolites, lipids and proteins. Homocitrulline, isoleucine and 2-aminoadipic ...

    • Identification of BST2 Contributing to the Development of Glioblastoma Based on Bioinformatics Analysis 

      Kong, Yang; Xue, Zhiwei; Wang, Haiying; Cui, Guangqiang; Chen, Anjing; Liu, Jie; Wang, Jian; Li, Xingang; Huang, Bin (Journal article; Peer reviewed, 2022)
      Rigorous molecular analysis of the immune cell environment and immune response of human tumors has led to immune checkpoint inhibitors as one of the most promising strategies for the treatment of human cancer. However, in ...

    • Identification of critical enzymes in the salmon louse chitin synthesis pathway as revealed by RNA interference-mediated abrogation of infectivity 

      Braden, Laura; Michaud, Dylan; Igboeli, Okechukwu O.; Dondrup, Michael; Hamre, Lars Are; Dalvin, Sussie; Purcell, Sara; Kongshaug, Heidi; Eichner, Christiane; Nilsen, Frank; Fast, Mark D. (Journal article; Peer reviewed, 2020)
      Treatment of infestation by the ectoparasite Lepeophtheirus salmonis relies on a small number of chemotherapeutant treatments that currently meet with limited success. Drugs targeting chitin synthesis have been largely ...