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    • AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells 

      Lotsberg, Maria Lie; Wnuk-Lipinska, Katarzyna; Terry, Stéphane; Tan, Tuan Zea; Lu, Ning; Trachsel-Moncho, Laura; Røsland, Gro Vatne; Siraji, Muntequa Ishtiaq; Hellesøy, Monica; Rayford, Austin James; Jacobsen, Kirstine; Ditzel, Henrik J; Vintermyr, Olav Karsten; Bivona, Trever G; Minna, John; Brekken, Rolf A; Baguley, Bruce; Micklem, David; Akslen, Lars A.; Gausdal, Gro; Simonsen, Anne; Thiery, Jean Paul; Chouaib, Salem; Lorens, James; Engelsen, Agnete (Journal article; Peer reviewed, 2020)
      Introduction Acquired cancer therapy resistance evolves under selection pressure of immune surveillance and favors mechanisms that promote drug resistance through cell survival and immune evasion. AXL receptor tyrosine ...

    • AXL targeting by a specific small molecule or monoclonal antibody inhibits renal cell carcinoma progression in an orthotopic mice model 

      Chen, Tony Jialiang; Mydel, Piotr Mateusz; Benedyk-Machaczka, Małgorzata; Kamińska, Marta; Kalucka, Urszula; Blø, Magnus; Furriol, Jessica; Gausdal, Gro; Lorens, James Bradley; Osman, Tarig Al-Hadi; Marti, Hans Peter (Journal article; Peer reviewed, 2021)
      AXL tyrosine kinase activation enhances cancer cell survival, migration, invasiveness, and promotes drug resistance. AXL overexpression is typically detected in a high percentage of renal cell carcinomas (RCCs) and is ...

    • AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells 

      Li, Huiyu; Liu, Zhida; Liu, Longchao; Zhang, Hongyi; Han, Chuanhui; Girard, Luc; Park, Hyunsil; Zhang, Anli; Dong, Chunbo; Ye, Jianfeng; Rayford, Austin James; Peyton, Michael; Li, Xiaoguang; Avila, Kimberley; Cao, Xuezhi; Hu, Shuiqing; Alam, Md Maksudul; Akbay, Esra A.; Solis, Luisa M.; Behrens, Carmen; Hernandez-Ruiz, Sharia; Lu, Wei; Wistuba, Ignacio; Heymach, John V.; Chisamore, Michael; Micklem, David Robert; Gabra, Hani; Gausdal, Gro; Lorens, James; Li, Bo; Fu, Yang-Xin; Minna, John D.; Brekken, Rolf A. (Journal article; Peer reviewed, 2022)
      Mutations in STK11/LKB1 in non-small cell lung cancer (NSCLC) are associated with poor patient responses to immune checkpoint blockade (ICB), and introduction of a Stk11/Lkb1 (L) mutation into murine lung adenocarcinomas ...

    • Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model 

      Hoel, August; Osman, Tarig; Hoel, Fredrik; Elsaid, Hassan Osman Alhassan; Chen, Tony; Landolt, Lea Zoe; Babickova, Janka; Tronstad, Karl Johan; Lorens, James B.; Gausdal, Gro; Marti, Hans-Peter; Furriol, Jessica (Journal article; Peer reviewed, 2021)
      Renal fibrosis is a progressive histological manifestation leading to chronic kidney disease (CKD) and associated with mitochondrial dysfunction. In previous work, we showed that Bemcentinib, an Axl receptor tyrosine kinase ...

    • Azimuthal correlations of prompt D mesons with charged particles in pp and p–Pb collisions at √sNN=5.02TeV 

      Acharya, Shreyasi; Adamová, Dagmar; Adler, Alexander; Adolfsson, Jonatan; Aggarwal, Madan M.; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Nikita; Ahammed, Zubayer; Ahmad, Shafiq F.; Alme, Johan; Altenkaemper, Lucas; Djuvsland, Øystein; Eikeland, Viljar Nilsen; Ersdal, Magnus Rentsch; Fionda, Fiorella Maria Celeste; Grøttvik, Ola Slettevoll; Lofnes, Ingrid Mckibben; Nystrand, Joakim; Rehman, Attiq Ur; Røhrich, Dieter; Tambave, Ganesh Jagannath; Ullaland, Kjetil; Wagner, Boris; Yang, Shiming; Yuan, Shiming; Zhou, Zhuo; Arsene, Ionut Cristian; Dordic, Olja; Lardeux, Antoine Xavier; Mahmood, Sohail Musa; Malik, Qasim Waheed; Neagu, Alexandra; Richter, Matthias; Røed, Ketil; Skaali, Toralf Bernhard; Tveter, Trine Spedstad; Wikne, Jon Christopher; Helstrup, Håvard; Hetland, Kristin Fanebust; Kileng, Bjarte; Nesbø, Simon Voigt; Storetvedt, Maksim Melnik; Langøy, Rune; Lien, Jørgen André; Ahn, Sang Un; Akindinov, Alexander; Al-Turany, Mohammed; Alam, Sk Noor; De Albuquerque, Danilo Silva; ALICE, Collaboration (Journal article; Peer reviewed, 2020-10-22)
      The measurement of the azimuthal-correlation function of prompt D mesons with charged particles in pp collisions at s√=5.02 TeV and p–Pb collisions at sNN−−−√=5.02 TeV with the ALICE detector at the LHC is reported. The ...

    • «Å leve i krysspresset mellom foreldrerollen og kreftsykdommen»- En kvalitativ studie av unge voksne kreftpasienters erfaringer 

      Hauken, May Aasebø; Løndalen, Lillian Levik; Iversen, Anette Christine (Journal article; Peer reviewed, 2021)
      Kreft i ung, voksen alder (18–35 år) er sjelden. Behandlingen er oftest aggressiv og langvarig med påfølgende fysiske og psykososiale senskader. Vi har imidlertid lite kunnskap om utfordringene unge voksne kreftpasienter ...

    • B cells and autoantibodies in AIRE deficiency 

      Wolff, Anette Susanne Bøe; Braun, Sarah; Husebye, Eystein Sverre; Oftedal, Bergithe Eikeland (Journal article; Peer reviewed, 2021)
      Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare but severe monogenetic autoimmune endocrine disease caused by failure of the Autoimmune Regulator (AIRE). AIRE regulates the negative selection of T cells in the ...

    • b-Coloring Parameterized by Clique-Width 

      Jaffke, Lars; Lima, Paloma Thome de; Lokshtanov, Daniel (Journal article; Peer reviewed, 2021)
      We provide a polynomial-time algorithm for b-Coloring on graphs of constant clique-width. This unifies and extends nearly all previously known polynomial-time results on graph classes, and answers open questions posed by ...

    • b-Coloring Parameterized by Clique-Width 

      Jaffke, Lars; Lima, Paloma T.; Lokshtanov, Daniel (Journal article; Peer reviewed, 2023)
      We provide a polynomial-time algorithm for b- Coloring on graphs of constant clique-width. This unifies and extends nearly all previously known polynomial time results on graph classes, and answers open questions posed by ...

    • B-vitamin Treatment Modifies the Mortality Risk Associated with Calcium Channel Blockers in Patients with Suspected Stable Angina Pectoris: A Prospective Cohort Study 

      Dhar, Indu; Svingen, Gard Frodahl Tveitevåg; Bjørnestad, Espen Øglænd; Ulvik, Arve; Saeed, Sahrai; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2023)
      Background Calcium channel blockers (CCBs) are used for the treatment of cardiovascular disease (CVD), including angina pectoris, and hypertension; however, the effect on survival remains uncertain. CCBs impair fibrinolysis ...

    • “Back to Eden”: An explorative qualitative study on traditional medicine use during pregnancy among selected women in Lusaka Province, Zambia 

      el Hajj, Magalie; Sitali, Doreen Chilolo; Vwalika, Bellington; Holst, Lone (Journal article; Peer reviewed, 2020)
      Background and purpose: No qualitative study on traditional medicine use among Zambian pregnant women has ever been conducted. Accordingly, this study was performed to explore the perceptions, motivations and experiences ...

    • Back to the basics of polar expeditions: personality hardiness, fear, and nutrition in polar environments 

      Johnsen, Bjørn Helge; Gjeldnes, Rune (Journal article; Peer reviewed, 2023)
      The present paper aims at presenting an overview of findings relating personality hardiness to adaptation to polar environments. Several studies from the Operational Psychology Research group at the University of Bergen ...

    • Background removal from global auroral images: Data driven dayglow modelling 

      Ohma, Anders; Madelaire, Michael; Laundal, Karl Magnus; Reistad, Jone Peter; Hatch, Spencer Mark; Gasparini, Sara; Walker, Simon (Journal article; Peer reviewed, 2023)
      Global images of auroras obtained by cameras on spacecraft are a key tool for studying the near-Earth environment. However, the cameras are sensitive not only to auroral emissions produced by precipitating particles, but ...

    • Backward evaluation in peer assessment: A scoping review 

      Misiejuk, Kamila; Wasson, Barbara (Journal article; Peer reviewed, 2021)
      Implementing backward evaluation as part of the peer assessment process enables students to react to the feedback they receive on their work within one peer assessment activity cycle. The emergence of online peer assessment ...

    • Bacteraemia, Malaria, and Case Fatality Among Children Hospitalized With Fever in Dar es Salaam, Tanzania 

      Moyo, Sabrina John; Manyahi, Joel; Blomberg, Bjørn; Tellevik, Marit Gjerde; Masoud, Nahya Salim; Aboud, Said; Manji, Karim; Roberts, Adam P.; Hanevik, Kurt; Mørch, Kristine; Langeland, Nina (Journal article; Peer reviewed, 2020)
      Background: Febrile illness is the commonest cause of hospitalization in children <5 years in sub-Saharan Africa, and bacterial bloodstream infections and malaria are major causes of death. Methods: From March 2017 to ...

    • Bacterial contamination of coffee and personal exposure to inhalable dust and endotoxin in primary coffee processing factories in Ethiopia 

      Abaya, Samson Wakuma; Bråtveit, Magne; Kumie, Abera; Deressa, Wakgari; Moen, Bente Elisabeth (Journal article; Peer reviewed, 2023)
      Introduction and objective: Endotoxins from gram-negative bacteria might be released when the coffee cherries are processed and may cause respiratory health problems among workers in the coffee industry. The relationship ...

    • Bag-in-the-lens intraocular lens in paediatric cataract surgery: intraoperative and postoperative outcomes 

      Boonstra, Nils-Erik; Haugen, Olav H. (Journal article; Peer reviewed, 2021)
      Purpose: To report intra- and postoperative surgical outcome using the bag-in-the-lens (BIL) technique in paediatric cataract surgery. Methods: In a retrospective case series, we studied the outcomes of children aged ...

    • Baked cod consumption delayed the development of kidney and liver dysfunction and affected plasma amino acid concentrations, but did not affect blood pressure, blood glucose or liver triacylglycerol concentrations in obese fa/fa Zucker rats. 

      Vikøren, Linn A.; Drotningsvik, Aslaug; Midttun, Øivind; McCann, Adrian; Bergseth, Marthe Tønder; Austgulen, Maren H.; Mellgren, Gunnar; Ueland, Per Magne; Gudbrandsen, Oddrun Anita (Journal article; Peer reviewed, 2021)
      Obesity is associated with changes in amino acid metabolism, and studies show that ingestion of fish proteins influence amino acid composition in plasma and urine, in addition to affecting risk factors for metabolic syndrome. ...

    • The balance between NAD+ biosynthesis and consumption in ageing 

      Strømland, Øyvind; Diab, Joseph; Ferrario, Eugenio; Sverkeli, Lars Jansen; Ziegler, Mathias (Journal article; Peer reviewed, 2021)
      Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme in redox reactions. NAD+ is also important in cellular signalling as it is consumed by PARPs, SARM1, sirtuins and CD38. Cellular NAD+ levels regulate several ...

    • Balanced judicious bipartition is fixed-parameter tractable 

      Lokshtanov, Daniel; Saurabh, Saket; Sharma, Roohani; Zehavi, Meirav (Journal article; Peer reviewed, 2019)
      The family of judicious partitioning problems, introduced by Bollobás and Scott to the field of extremal combinatorics, has been extensively studied from a structural point of view for over two decades. This rich realm of ...