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    • The Truth behind the Zeros: A New Approach to Principal Component Analysis of the Neuropsychiatric Inventory 

      Hellton, Kristoffer Herland; Cummings, Jeffrey; Vik-Mo, Audun Osland; Nordrehaug, Jan Erik; Aarsland, Dag; Selbæk, Geir; Melvær, Giil Lasse (Journal article; Peer reviewed, 2021)
      Psychiatric syndromes in dementia are often derived from the Neuropsychiatric Inventory (NPI) using principal component analysis (PCA). The validity of this statistical approach can be questioned, since the excessive ...

    • Truths from Morocco: Knowledge Production and Danish-Moroccan Encounters in the Eighteenth Century 

      Skålevåg, Svein Atle (Journal article; Peer reviewed, 2023)
      In the 1750s the Danish kingdom and the Moroccan Empire came into contact, and concluded a bilateral treaty. As part of the accord, a Danish chartered company was established. The company was short-lived and the “special ...

    • Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients 

      Ulvik, Arve; Midttun, Øivind; McCann, Adrian; Meyer, Klaus; Tell, Grethe S.; Nygård, Ottar; Ueland, Per Magne (Journal article; Peer reviewed, 2020)
      Background Vitamin B-6 status is routinely measured as pyridoxal 5′-phosphate (PLP) in plasma. Low concentrations of PLP are associated with rheumatic, cardiovascular, and neoplastic diseases. We have previously shown ...

    • Tsunami risk communication and management: Contemporary gaps and challenges 

      Rafliana, Irina; Jalayer, Fatemeh; Cerase, Andrea; Cugliari, Lorenzo; Baiguera, Marco; Salmanidou, Dimitra; Necmioglu, Öcal; Aguirre-Ayerbe, Ignacio; Lorito, Stefano; Fraser, Stuart; Løvholt, Finn; Babeyko, Andrey; Salgado-Gálvez, Mario A.; Selva, Jacopo; De Risi, Raffaele; Sørensen, Mathilde Bøttger; Behrens, Jörn; Aniel-Quiroga, Iñigo; Del Zoppo, Marta; Belliazzi, Stefano; Pranantyo, Ignatius Ryan; Amato, Alessandro; Hancilar, Ufuk (Journal article; Peer reviewed, 2022)
      Very large tsunamis are associated with low probabilities of occurrence. In many parts of the world, these events have usually occurred in a distant time in the past. As a result, there is low risk perception and a lack ...

    • Tuberculosis-Associated Hemophagocytic Lymphohistiocytosis: A Review of Current Literature 

      Fauchald, Trym; Blomberg, Bjørn; Reikvam, Håkon (Journal article; Peer reviewed, 2023)
      Hemophagocytic lymphohistiocytosis (HLH) is a condition of immune dysregulation and hyperinflammation, leading to organ failure and death. Malignancy, autoimmune conditions, and infections, including Mycobacterium tuberculosis ...

    • Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report 

      Bjerkli, Inger-Heidi; Laurvik, Helene; Nginamau, Elisabeth Sivy; Søland, Tine Merete; Costea, Daniela Elena; Hov, Håkon; Uhlin-Hansen, Lars; Hadler-Olsen, Elin Synnøve; Steigen, Sonja Eriksson (Journal article; Peer reviewed, 2020)
      Background The majority of oral cavity cancers arise in the oral tongue. The aim of this study was to evaluate the prognostic value of tumor budding in oral tongue squamous cell carcinoma, both as a separate variable and ...

    • Tumor HPV status, level of regulatory T cells and macrophage infiltration predict up to 20-year non-disease-specific survival in oropharynx squamous cell carcinoma patients 

      Haave, Hilde; Ljøkjel, Borghild; Lybak, Helene; Moe, Svein Erik Emblem; Berge, Jan Erik; Vintermyr, Olav Karsten; Helgeland, Lars; Aarstad, Hans Jørgen (Journal article; Peer reviewed, 2022)
      Oropharynx squamous cell carcinoma (OPSCC) is of special interest because human papilloma virus (HPV) and/or smoking cause this disease. Influxes of inflammatory cells into such tumors are known to vary with prognoses. ...

    • Tumor infiltration levels of CD3, Foxp3 (+) lymphocytes and CD68 macrophages at diagnosis predict 5-year disease-specific survival in patients with oropharynx squamous cell carcinoma 

      Ljøkjel, Borghild; Haave, Hilde; Lybak, Stein; Vintermyr, Olav Karsten; Helgeland, Lars; Aarstad, Hans Jørgen (Journal article; Peer reviewed, 2022)
      Head and neck cancer (HNC) is the sixth most common cancer worldwide. Oropharyngeal (OP) cancers are of special interest because of possible underlying HPV infection which is tied to prognosis. Influxes of inflammatory ...

    • Tumor-associated lymphocytes and macrophages are related to stromal elastosis and vascular invasion in breast cancer 

      Chen, Ying; Klingen, Tor Audun; Aas, Hans; Wik, Elisabeth; Akslen, Lars Andreas (Journal article; Peer reviewed, 2021)
      The tumor microenvironment plays a critical role in breast cancer progression. Here, we investigated tumor-infiltrating lymphocytes (TILs) and associations with macrophage numbers, tumor stromal elastosis, vascular invasion, ...

    • Tumor-associated macrophages in gliomas—basic insights and treatment opportunities 

      Andersen, Johannes Kaasa; Miletic, Hrvoje; Hossain, Md Jubayer al (Journal article; Peer reviewed, 2022)
      Glioma refers to a group of primary brain tumors which includes glioblastoma (GBM), astrocytoma and oligodendroglioma as major entities. Among these, GBM is the most frequent and most malignant one. The highly infiltrative ...

    • Tumor-Derived Lactic Acid Contributes to the Paucity of Intratumoral ILC2s 

      Wagner, Marek; Ealey, Kafi N; Tetsu, Hiroe; Kiniwa, Tsuyoshi; Motomura, Yasutaka; Moro, Kazuyo; Koyasu, Shigeo (Journal article; Peer reviewed, 2020)
      Group 2 innate lymphoid cells (ILC2s) are abundant in non-lymphoid tissues and increase following infectious and inflammatory insults. In solid tumors, however, ILC2s constitute a relatively small proportion of immune ...

    • Tumor-penetrating peptide for systemic targeting of Tenascin-C 

      Lingasamy, Prakash; Tobi, Allan; Kurm, Kaarel; Kopanchuk, Sergei; Sudakov, Aleksander; Salumäe, Markko; Rätsep, Tõnu; Asser, Toomas; Bjerkvig, Rolf; Teesalu, Tambet (Journal article; Peer reviewed, 2020)
      Extracellular matrix in solid tumors has emerged as a specific, stable, and abundant target for affinity-guided delivery of anticancer drugs. Here we describe the homing peptide that interacts with the C-isoform of Tenascin-C ...

    • Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer 

      Ytre-Hauge, Sigmund; Salvesen, Øyvind; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021-01)
      Background: To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ...

    • Tuning and Development of an Individual-Based Model of the Herring Spawning Migration 

      Kelly, Cian; Michelsen, Finn Are; Kolding, Jeppe; Alver, Morten (Journal article; Peer reviewed, 2022-01-13)
      Norwegian spring spawning herring is a migratory pelagic fish stock that seasonally navigates between distant locations in the Norwegian Sea. The spawning migration takes place between late winter and early spring. In this ...

    • Tuning the electronic band structure of metal surfaces for enhancing high-order harmonic generation 

      Agueny, Hicham (Journal article; Peer reviewed, 2021)
      High-harmonic generation (HHG) from the condensed matter phase holds promise to promote future cutting-edge research in the emerging field of attosecond nanoscopy. The key for the progress of the field relies on the ...

    • Turbidites, topography and tectonics: Evolution of submarine channel-lobe systems in the salt-influenced Kwanza Basin, offshore Angola 

      Howlett, Danielle; Gawthorpe, Rob; Ge, Zhiyuan; Rotevatn, Atle; Jackson, Christopher A.-L. (Journal article; Peer reviewed, 2021)
      Understanding the evolution of submarine channel‐lobe systems on salt‐influenced slopes is challenging as these systems react to subtle, syn‐depositional changes in sea‐floor topography. The impact of large blocking ...

    • Turbulence in a coastal environment: the case of Vindeby 

      Putri, Rieska Mawarni; Cheynet, Etienne; Obhrai, Charlotte; Jakobsen, Jasna Bogunovic (Journal article; Peer reviewed, 2022)
      The one-point and two-point power spectral densities of the wind velocity fluctuations are studied using the observations from an offshore mast at Vindeby Offshore Wind Farm, for a wide range of thermal stratifications of ...

    • Turnover of IPS employment specialists: Rates and predictors 

      Butenko, Daniil; Rinaldi, Miles; Brinchmann, Beate; Killackey, Eoin; Johnsen, Erik; Mykletun, Arnstein (Journal article; Peer reviewed, 2022)
      Background: There are anecdotal reports of high job turnover of Individual Placement and Support employment specialists. However, no studies have addressed this issue. Objective: To explore whether turnover rates among ...

    • Twenty years of Dipterology through the pages of Zootaxa 

      Whitmore, Daniel; Gaimari, Stephen D.; Nihei, Silvio S.; Evenhuis, Neal L.; Kurina, Olavi; Borkent, Christopher J.; Sinclair, Bradley J.; O'Hara, James E.; Zhang, Zhi-Qiang; Moulton, John K.; Ribeiro, Guilherme Cunha; Bickel, Daniel J.; Gilka, Wojciech; Andersen, Trond; Rossaro, Bruno; Whittington, Andrew E.; Lamas, Carlos José Einicker; Heller, Kai; Kehlmaier, Christian; Courtney, Gregory W.; Kerr, Peter H.; Blagoderov, Vladimir (Journal article; Peer reviewed, 2021)
      We present a summary and analysis of the Diptera-related information published in Zootaxa from 2001 to 2020, with a focus on taxonomic papers. Altogether, 2,527 papers on Diptera were published, including 2,032 taxonomic ...

    • Twenty-One Years of Phytoplankton Bloom Phenology in the Barents, Norwegian, and North Seas 

      Silva, Edson; Counillon, François; Brajard, Julien; Korosov, Anton; Pettersson, Lasse H; Samuelsen, Annette; Keenlyside, Noel (Journal article; Peer reviewed, 2021)
      Phytoplankton blooms provide biomass to the marine trophic web, contribute to the carbon removal from the atmosphere and can be deadly when associated with harmful species. This points to the need to understand the phenology ...