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    • Tumor-associated lymphocytes and macrophages are related to stromal elastosis and vascular invasion in breast cancer 

      Chen, Ying; Klingen, Tor Audun; Aas, Hans; Wik, Elisabeth; Akslen, Lars Andreas (Journal article; Peer reviewed, 2021)
      The tumor microenvironment plays a critical role in breast cancer progression. Here, we investigated tumor-infiltrating lymphocytes (TILs) and associations with macrophage numbers, tumor stromal elastosis, vascular invasion, ...

    • Tumor-associated macrophages in gliomas—basic insights and treatment opportunities 

      Andersen, Johannes Kaasa; Miletic, Hrvoje; Hossain, Md Jubayer al (Journal article; Peer reviewed, 2022)
      Glioma refers to a group of primary brain tumors which includes glioblastoma (GBM), astrocytoma and oligodendroglioma as major entities. Among these, GBM is the most frequent and most malignant one. The highly infiltrative ...

    • Tumor-Derived Lactic Acid Contributes to the Paucity of Intratumoral ILC2s 

      Wagner, Marek; Ealey, Kafi N; Tetsu, Hiroe; Kiniwa, Tsuyoshi; Motomura, Yasutaka; Moro, Kazuyo; Koyasu, Shigeo (Journal article; Peer reviewed, 2020)
      Group 2 innate lymphoid cells (ILC2s) are abundant in non-lymphoid tissues and increase following infectious and inflammatory insults. In solid tumors, however, ILC2s constitute a relatively small proportion of immune ...

    • Tumor-penetrating peptide for systemic targeting of Tenascin-C 

      Lingasamy, Prakash; Tobi, Allan; Kurm, Kaarel; Kopanchuk, Sergei; Sudakov, Aleksander; Salumäe, Markko; Rätsep, Tõnu; Asser, Toomas; Bjerkvig, Rolf; Teesalu, Tambet (Journal article; Peer reviewed, 2020)
      Extracellular matrix in solid tumors has emerged as a specific, stable, and abundant target for affinity-guided delivery of anticancer drugs. Here we describe the homing peptide that interacts with the C-isoform of Tenascin-C ...

    • Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer 

      Ytre-Hauge, Sigmund; Salvesen, Øyvind; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021-01)
      Background: To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ...

    • Tuning and Development of an Individual-Based Model of the Herring Spawning Migration 

      Kelly, Cian; Michelsen, Finn Are; Kolding, Jeppe; Alver, Morten (Journal article; Peer reviewed, 2022-01-13)
      Norwegian spring spawning herring is a migratory pelagic fish stock that seasonally navigates between distant locations in the Norwegian Sea. The spawning migration takes place between late winter and early spring. In this ...

    • Tuning the electronic band structure of metal surfaces for enhancing high-order harmonic generation 

      Agueny, Hicham (Journal article; Peer reviewed, 2021)
      High-harmonic generation (HHG) from the condensed matter phase holds promise to promote future cutting-edge research in the emerging field of attosecond nanoscopy. The key for the progress of the field relies on the ...

    • Turbidites, topography and tectonics: Evolution of submarine channel-lobe systems in the salt-influenced Kwanza Basin, offshore Angola 

      Howlett, Danielle; Gawthorpe, Rob; Ge, Zhiyuan; Rotevatn, Atle; Jackson, Christopher A.-L. (Journal article; Peer reviewed, 2021)
      Understanding the evolution of submarine channel‐lobe systems on salt‐influenced slopes is challenging as these systems react to subtle, syn‐depositional changes in sea‐floor topography. The impact of large blocking ...

    • Turbulence in a coastal environment: the case of Vindeby 

      Putri, Rieska Mawarni; Cheynet, Etienne; Obhrai, Charlotte; Jakobsen, Jasna Bogunovic (Journal article; Peer reviewed, 2022)
      The one-point and two-point power spectral densities of the wind velocity fluctuations are studied using the observations from an offshore mast at Vindeby Offshore Wind Farm, for a wide range of thermal stratifications of ...

    • Turnover of IPS employment specialists: Rates and predictors 

      Butenko, Daniil; Rinaldi, Miles; Brinchmann, Beate; Killackey, Eoin; Johnsen, Erik; Mykletun, Arnstein (Journal article; Peer reviewed, 2022)
      Background: There are anecdotal reports of high job turnover of Individual Placement and Support employment specialists. However, no studies have addressed this issue. Objective: To explore whether turnover rates among ...

    • Twenty years of Dipterology through the pages of Zootaxa 

      Whitmore, Daniel; Gaimari, Stephen D.; Nihei, Silvio S.; Evenhuis, Neal L.; Kurina, Olavi; Borkent, Christopher J.; Sinclair, Bradley J.; O'Hara, James E.; Zhang, Zhi-Qiang; Moulton, John K.; Ribeiro, Guilherme Cunha; Bickel, Daniel J.; Gilka, Wojciech; Andersen, Trond; Rossaro, Bruno; Whittington, Andrew E.; Lamas, Carlos José Einicker; Heller, Kai; Kehlmaier, Christian; Courtney, Gregory W.; Kerr, Peter H.; Blagoderov, Vladimir (Journal article; Peer reviewed, 2021)
      We present a summary and analysis of the Diptera-related information published in Zootaxa from 2001 to 2020, with a focus on taxonomic papers. Altogether, 2,527 papers on Diptera were published, including 2,032 taxonomic ...

    • Twenty-One Years of Phytoplankton Bloom Phenology in the Barents, Norwegian, and North Seas 

      Silva, Edson; Counillon, François; Brajard, Julien; Korosov, Anton; Pettersson, Lasse H; Samuelsen, Annette; Keenlyside, Noel (Journal article; Peer reviewed, 2021)
      Phytoplankton blooms provide biomass to the marine trophic web, contribute to the carbon removal from the atmosphere and can be deadly when associated with harmful species. This points to the need to understand the phenology ...

    • Twinning-by-Construction: Ensuring Correctness for Self-adaptive Digital Twins 

      Kamburjan, Eduard; Din, Crystal Chang; Schlatte, Rudolf; Tapia Tarifa, Silvia Lizeth; Johnsen, Einar Broch (Journal article; Peer reviewed, 2022)
      Digital twin applications use digital artefacts to twin physical systems. The purpose is to continuously mirror the structure and behavior of the physical system, such that users can analyse the physical system by means ...

    • Two apolipoproteins in salmon louse (Lepeophtheirus salmonis), apolipoprotein 1 knock down reduces reproductive capacity 

      Khan, Muhammad Tanveer; Dalvin, Sussie; Nilsen, Frank; Male, Rune (Journal article; Peer reviewed, 2021)
      The salmon louse, Lepeophtheirus salmonis is an ectoparasite of salmonid fish in the Northern Hemisphere, causing large economical losses in the aquaculture industry and represent a threat to wild populations of salmonids. ...

    • Two dark matter candidates in three-Higgs-doublet models with S3 symmetry 

      Kuncinas, Anton; Øgreid, Odd Magne; Osland, Per; Rebelo, Margarida Nesbitt (Journal article; Peer reviewed, 2022)
      Models with an extended scalar electroweak sector can have vanishing vacuum expectation values in a basis where an underlying symmetry is imposed. Such extensions are very well motivated. If a symmetry prevents couplings ...

    • Two decades of match-mismatch in Northeast Arctic cod – Feeding conditions and survival 

      Kajiya Endo, Clarissa Akemi; Stige, Leif Christian; Skogen, Morten D.; Ciannelli, Lorenzo; Vikebø, Frode Bendiksen (Journal article; Peer reviewed, 2022)
      The successful recruitment of Northeast Arctic (NEA) cod is thought to depend on sufficient and suitable prey for the newly hatched larvae, in particular the nauplii stages of the lipid-rich calanoid copepod species Calanus ...

    • Two hundred years of zooplankton vertical migration research 

      Bandara, Kanchana; Varpe, Øystein; Wijewardene, Lishani; Tverberg, Vigdis; Eiane, Ketil (Journal article; Peer reviewed, 2021)
      Vertical migration is a geographically and taxonomically widespread behaviour among zooplankton that spans across diel and seasonal timescales. The shorter-term diel vertical migration (DVM) has a periodicity of up to 1 ...

    • Two new deep-water species of Ampharetidae (Annelida: Polychaeta) from the eastern Australian continental margin 

      Gunton, Laetitia M; Kupriyanova, Elena K.; Alvestad, Tom (Journal article; Peer reviewed, 2020-08-12)
      Two new species, Melinnopsis gardelli sp. nov. and Melinnopsis chadwicki sp. nov. (Annelida, Ampharetidae, Melinninae), are described from deep waters off the east coast of Australia. One hundred and 11 specimens were ...

    • Two New Families of Quadratic APN Functions 

      Li, Kangquan; Zhou, Yue; Li, Chunlei; Qu, Longjiang (Journal article; Peer reviewed, 2022)

    • Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases 

      Jellas, Khadija el; Dušátková, Petra; Haldorsen, Ingfrid S.; Molnes, Janne; Tjora, Erling; Johansson, Bente Berg; Fjeld, Karianne; Johansson, Stefan; Průhová, Štěpánka; Groop, Leif; Löhr, J. Matthias; Njølstad, Pål Rasmus; Molven, Anders (Journal article; Peer reviewed, 2022)
      Context Maturity onset diabetes of the young, type 8 (MODY8) is associated with mutations in the CEL gene, which encodes the digestive enzyme carboxyl ester lipase. Several diabetes cases and families have in recent years ...