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Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report
(Journal article; Peer reviewed, 2020)Background The majority of oral cavity cancers arise in the oral tongue. The aim of this study was to evaluate the prognostic value of tumor budding in oral tongue squamous cell carcinoma, both as a separate variable and ... -
Tumor HPV status, level of regulatory T cells and macrophage infiltration predict up to 20-year non-disease-specific survival in oropharynx squamous cell carcinoma patients
(Journal article; Peer reviewed, 2022)Oropharynx squamous cell carcinoma (OPSCC) is of special interest because human papilloma virus (HPV) and/or smoking cause this disease. Influxes of inflammatory cells into such tumors are known to vary with prognoses. ... -
Tumor infiltration levels of CD3, Foxp3 (+) lymphocytes and CD68 macrophages at diagnosis predict 5-year disease-specific survival in patients with oropharynx squamous cell carcinoma
(Journal article; Peer reviewed, 2022)Head and neck cancer (HNC) is the sixth most common cancer worldwide. Oropharyngeal (OP) cancers are of special interest because of possible underlying HPV infection which is tied to prognosis. Influxes of inflammatory ... -
Tumor-associated lymphocytes and macrophages are related to stromal elastosis and vascular invasion in breast cancer
(Journal article; Peer reviewed, 2021)The tumor microenvironment plays a critical role in breast cancer progression. Here, we investigated tumor-infiltrating lymphocytes (TILs) and associations with macrophage numbers, tumor stromal elastosis, vascular invasion, ... -
Tumor-associated macrophages in gliomas—basic insights and treatment opportunities
(Journal article; Peer reviewed, 2022)Glioma refers to a group of primary brain tumors which includes glioblastoma (GBM), astrocytoma and oligodendroglioma as major entities. Among these, GBM is the most frequent and most malignant one. The highly infiltrative ... -
Tumor-Derived Lactic Acid Contributes to the Paucity of Intratumoral ILC2s
(Journal article; Peer reviewed, 2020)Group 2 innate lymphoid cells (ILC2s) are abundant in non-lymphoid tissues and increase following infectious and inflammatory insults. In solid tumors, however, ILC2s constitute a relatively small proportion of immune ... -
Tumor-penetrating peptide for systemic targeting of Tenascin-C
(Journal article; Peer reviewed, 2020)Extracellular matrix in solid tumors has emerged as a specific, stable, and abundant target for affinity-guided delivery of anticancer drugs. Here we describe the homing peptide that interacts with the C-isoform of Tenascin-C ... -
Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer
(Journal article; Peer reviewed, 2021-01)Background: To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ... -
Tuning and Development of an Individual-Based Model of the Herring Spawning Migration
(Journal article; Peer reviewed, 2022-01-13)Norwegian spring spawning herring is a migratory pelagic fish stock that seasonally navigates between distant locations in the Norwegian Sea. The spawning migration takes place between late winter and early spring. In this ... -
Tuning the electronic band structure of metal surfaces for enhancing high-order harmonic generation
(Journal article; Peer reviewed, 2021)High-harmonic generation (HHG) from the condensed matter phase holds promise to promote future cutting-edge research in the emerging field of attosecond nanoscopy. The key for the progress of the field relies on the ... -
Turbidites, topography and tectonics: Evolution of submarine channel-lobe systems in the salt-influenced Kwanza Basin, offshore Angola
(Journal article; Peer reviewed, 2021)Understanding the evolution of submarine channel‐lobe systems on salt‐influenced slopes is challenging as these systems react to subtle, syn‐depositional changes in sea‐floor topography. The impact of large blocking ... -
Turbulence in a coastal environment: the case of Vindeby
(Journal article; Peer reviewed, 2022)The one-point and two-point power spectral densities of the wind velocity fluctuations are studied using the observations from an offshore mast at Vindeby Offshore Wind Farm, for a wide range of thermal stratifications of ... -
Turnover of IPS employment specialists: Rates and predictors
(Journal article; Peer reviewed, 2022)Background: There are anecdotal reports of high job turnover of Individual Placement and Support employment specialists. However, no studies have addressed this issue. Objective: To explore whether turnover rates among ... -
Twenty years of Dipterology through the pages of Zootaxa
(Journal article; Peer reviewed, 2021)We present a summary and analysis of the Diptera-related information published in Zootaxa from 2001 to 2020, with a focus on taxonomic papers. Altogether, 2,527 papers on Diptera were published, including 2,032 taxonomic ... -
Twenty-One Years of Phytoplankton Bloom Phenology in the Barents, Norwegian, and North Seas
(Journal article; Peer reviewed, 2021)Phytoplankton blooms provide biomass to the marine trophic web, contribute to the carbon removal from the atmosphere and can be deadly when associated with harmful species. This points to the need to understand the phenology ... -
Twinning-by-Construction: Ensuring Correctness for Self-adaptive Digital Twins
(Journal article; Peer reviewed, 2022)Digital twin applications use digital artefacts to twin physical systems. The purpose is to continuously mirror the structure and behavior of the physical system, such that users can analyse the physical system by means ... -
Two apolipoproteins in salmon louse (Lepeophtheirus salmonis), apolipoprotein 1 knock down reduces reproductive capacity
(Journal article; Peer reviewed, 2021)The salmon louse, Lepeophtheirus salmonis is an ectoparasite of salmonid fish in the Northern Hemisphere, causing large economical losses in the aquaculture industry and represent a threat to wild populations of salmonids. ... -
Two dark matter candidates in three-Higgs-doublet models with S3 symmetry
(Journal article; Peer reviewed, 2022)Models with an extended scalar electroweak sector can have vanishing vacuum expectation values in a basis where an underlying symmetry is imposed. Such extensions are very well motivated. If a symmetry prevents couplings ... -
Two decades of match-mismatch in Northeast Arctic cod – Feeding conditions and survival
(Journal article; Peer reviewed, 2022)The successful recruitment of Northeast Arctic (NEA) cod is thought to depend on sufficient and suitable prey for the newly hatched larvae, in particular the nauplii stages of the lipid-rich calanoid copepod species Calanus ... -
Two hundred years of zooplankton vertical migration research
(Journal article; Peer reviewed, 2021)Vertical migration is a geographically and taxonomically widespread behaviour among zooplankton that spans across diel and seasonal timescales. The shorter-term diel vertical migration (DVM) has a periodicity of up to 1 ...