Blar i University of Bergen Library på forfatter "Haavik, Jan"
-
Elevated body weight modulates subcortical volume change and associated clinical response following electroconvulsive therapy
Opel, Nils; Narr, Katherine L; Abbott, Christopher; Argyelan, Miklos; Espinoza, Randall; Emsell, Louise; Bouckaert, Filip; Sienaert, Pascal; Vandenbulcke, Mathieu; Nordanskog, Pia; Repple, Jonathan; Kavakbasi, Erhan; Jorgensen, Martin B.; Paulson, Olaf B.; Hanson, Lars G.; Dols, Annemieke; van Exel, Eric; Oudega, Mardien L.; Takamiya, Akihiro; Kishimoto, Taishiro; Ousdal, Olga Therese; Haavik, Jan; Hammar, Åsa Karin; Ødegaard, Ketil Joachim; Kessler, Ute; Bartsch, Hauke; Dale, Anders M.; Baune, Bernhard T; Dannlowski, Udo; Oltedal, Leif; Redlich, Ronny (Journal article; Peer reviewed, 2021)Background: Obesity is a frequent somatic comorbidity of major depression, and it has been associated with worse clinical outcomes and brain structural abnormalities. Converging evidence suggests that electroconvulsive ... -
Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis
Zhang-James, Yanli; Helminen, Emily C.; Liu, Jinru; Busatto, Geraldo F.; Calvo, Anna; Cercignani, Mara; Chaim-Avancini, Tiffany M.; Gabel, Matt C.; Harrison, Neil A.; Lazaro, Luisa; Lera-Miguel, Sara; Louza, Mario R.; Nicolau, Rosa; Rosa, Pedro G.; Schulte-Rutte, Martin; Zanetti, Marcus V.; Ambrosino, Sara; Asherson, Philip; Banaschewski, Tobias; Baranov, Alexandr; Baumeister, Sarah; Baur-Streubel, Ramona; Bellgrove, Mark A.; Biederman, Joseph; Bralten, Janita; Bramati, Ivanei; Brandeis, Daniel; Brem, Silvia; Buitelaar, Jan K.; Castellanos, Francisco X.; Chantiluke, Kaylita C.; Christakou, Anastasia; Coghill, David; Conzelmann, Annette; Cubillo, Ana; Dale, Anders M.; de Zeeuw, Patrick; Doyle, Alysa E.; Durston, Sarah; Earl, Eric A.; Epstein, Jeffery N.; Ethofer, Thomas; Fair, Damien A.; Fallgatter, Andreas J.; Frodl, Thomas; Gogberashvili, Tinatin; Haavik, Jan; Hartman, Catharina A.; Heslenfeld, Dirk J.; Hoekstra, Pieter J.; Hohmann, Sarah; Høvik, Marie Farstad; Jahanshad, Neda; Jernigan, Terry L.; Kardatzki, Bernd; Karkashadze, George A.; Kelly, Clare; Kohls, Gregor; Konrad, Kerstin; Kuntsi, Jonna; Lesch, Klaus-Peter; Lundervold, Astri J.; Malpas, Charles B.; Mattos, Paulo; McCarthy, Hazel; Mehta, Mitul A.; Namazova-Baranova, Leyla; Nigg, Joel T.; Novotny, Stephanie E.; O’Gorman Tuura, Ruth L.; Weiss, Eileen Oberwelland; Oosterlaan, Jaap; Oranje, Bob; Paloyelis, Yannis; Pauli, Paul; Plessen, Kerstin J.; Ramos-Quiroga, Josep Antoni; Reif, Andreas; Reneman, Liesbeth; Rubia, Katya; Schrantee, Anouk; Schwarz, Lena; Schweren, Lizanne J.S.; Seitz, Jochen; Shaw, Philip; Silk, Tim J.; Skokauskas, Norbert; Vila, Juan Carlos Soliva; Stevens, Michael C.; Sudre, Gustavo; Tamm, Leanne; Thompson, Paul M.; Tovar-Moll, Fernanda; van Erp, Theo G.M.; Vance, Alasdair; Vilarroya, Oscar; Vives-Gilabert, Yolanda; von Polier, Georg G.; Walitza, Susanne; Yoncheva, Yuliya N.; Ziegler, Georg C.; Franke, Barbara; Hoogman, Martine; Faraone, Stephen (Journal article; Peer reviewed, 2021)Attention-deficit/hyperactivity disorder (ADHD) affects 5% of children world-wide. Of these, two-thirds continue to have impairing symptoms of ADHD into adulthood. Although a large literature implicates structural brain ... -
An Exploratory Investigation of Goal Management Training in Adults With ADHD: Improvements in Inhibition and Everyday Functioning
Jensen, Daniel André; Halmøy, Anne; Stubberud, Jan Egil; Haavik, Jan; Lundervold, Astri J.; Sørensen, Lin (Journal article; Peer reviewed, 2021)Background: Adults with attention deficit/hyperactivity disorder (ADHD) are predominantly treated with medication. However, there is also a need for effective, psychologically based interventions. As ADHD is strongly ... -
Familial co-aggregation of attention-deficit/ hyperactivity disorder and autoimmune diseases: a cohort study based on Swedish population-wide registers
Hegvik, Tor-Arne; Chen, Qi; Kuja-Halkola, Ralf; Klungsøyr, Kari; Butwicka, Agnieszka; Lichtenstein, Paul; Almqvist, Catarina; Faraone, Stephen V.; Haavik, Jan; Larsson, Henrik (Journal article; Peer reviewed, 2021)Background Attention-deficit/hyperactivity disorder (ADHD) has been associated with several autoimmune diseases (AD), both within individuals and across relatives, implying common underlying genetic or environmental factors ... -
GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production
Mahootchi, Elaheh; Homaei, Selina Cannon; Kleppe, Rune; Winge, Ingeborg; Hegvik, Tor-Arne; Perez, Roberto Megias; Totland, Christian; Mogavero, Floriana; Baumann, Anne; Glennon, Jeffrey Colm; Miletic, Hrvoje; Kursula, Petri; Haavik, Jan (Journal article; Peer reviewed, 2020)Carnosine and related β-alanine–containing peptides are believed to be important antioxidants, pH buffers, and neuromodulators. However, their biosynthetic routes and therapeutic potential are still being debated. This ... -
Gene-Environment Interactions in Attention-Deficit/Hyperactivity Disorder Symptom Dimensions: The Role of Unhealthy Food Habits
Li, Lin; Taylor, Mark J; Bälter, Katarina; xie, tian; Solberg, Berit Skretting; Haavik, Jan; Arias-Vásquez, Alejandro; Hartman, Catharina A; Larsson, Henrik (Journal article; Peer reviewed, 2021)Background: Dietary habits were investigated as environmental risk factors for Attention-Deficit/Hyperactivity Disorder (ADHD). However, no previous studies explored the effects of dietary factors on modifying the role of ... -
Genetic association study of childhood aggression across raters, instruments, and age
Ip, Hill F.; van der Laan, Camiel M.; Krapohl, Eva M. L.; Brikell, Isabell; Sánchez-Mora, Cristina; Nolte, Ilja M.; Pourcain, Beate St; Bolhuis, Koen; Palviainen, Teemu; Zafarmand, Hadi; Colodro-Conde, Lucía; Gordon, Scott; Zayats, Tetyana; Aliev, Fazil; Jiang, Chang; Wang, Carol A.; Saunders, Gretchen; Karhunen, Ville; Hammerschlag, Anke R.; Adkins, Daniel E.; Border, Richard; Peterson, Roseann E.; Prinz, Joseph A.; Thiering, Elisabeth; Seppälä, Iikka; Vilor-Tejedor, Natàlia; Ahluwalia, Tarunveer S.; Day, Felix R.; Hottenga, Jouke-Jan; Allegrini, Andrea G.; Rimfeld, Kaili; Chen, Qi; Yi, Lu; Martin, Joanna; Soler Artigas, Marìa; Rovira, Paula; Bosch, Rosa; Español, Gemma; Ramos-Quiroga, Josep Antonio; Neumann, Alexander; Haavik, Jan; Harris, Jennifer Ruth; Helgeland, Øyvind; Johansson, Stefan; Knudsen, Gun Peggy Strømstad; Njølstad, Pål Rasmus; Havdahl, Alexandra; Magnus, Per Minor; Reichborn-Kjennerud, Ted; Boomsma, Dorret I. (Journal article; Peer reviewed, 2021)Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from ... -
Genome Guided Personalized Drug Therapy in Attention Deficit Hyperactivity Disorder
Haavik, Jan (Journal article; Peer reviewed, 2022)ADHD is a common behavioral syndrome with a heritability of 70–80%. Genome wide sequencing and association studies indicate that ADHD risk variants are distributed across a wide range of allele frequencies and relative ... -
Goal management training improves executive control in adults with ADHD: an open trial employing attention network theory to examine effects on attention
Jensen, Daniel Andre; Lundervold, Astri J.; Stubberud, Jan Egil; Halmøy, Anne; Haavik, Jan; Sørensen, Lin (Journal article; Peer reviewed, 2022)Background Adults with Attention-Deficit/Hyperactivity Disorder (ADHD) typically experience poorer attentional control. According to the attention network theory, attentional control relies on three interacting networks ... -
Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole—In Vitro and In Vivo Investigations
Betari, Nibal; Sahlholm, Kristoffer; Morató, Xavier; Godoy-Marín, Héctor; Jáuregui, Olga; Teigen, Knut; Ciruela, Francisco; Haavik, Jan (Journal article; Peer reviewed, 2020)Serotonin (5-HT) is a hormone and neurotransmitter that modulates neural activity as well as a wide range of other physiological processes including cardiovascular function, bowel motility, and platelet aggregation. 5-HT ... -
Innovative approaches in investigating inter-beat intervals: Graph theoretical method suggests altered autonomic functioning in adolescents with ADHD
Kvadsheim, Elisabet; Fasmer, Ole Bernt; Fasmer, Erlend Eindride; Hauge, Erik Rønneberg; Thayer, Julian F.; Osnes, Berge; Haavik, Jan; Koenig, Julian; Adolfsdottir, Steinunn; Plessen, Kerstin J.; Sørensen, Lin (Journal article; Peer reviewed, 2022)Cardiac inter-beat intervals (IBIs) are considered to reflect autonomic functioning and self-regulatory abilities and are often investigated by traditional time- and frequency domain analyses. These analyses investigate ... -
Insomnia, Alcohol Consumption and ADHD Symptoms in Adults
Lundervold, Astri J.; Jensen, Daniel André; Haavik, Jan (Journal article; Peer reviewed, 2020)Introduction Substance use disorders and insomnia are common in the general population, and particularly among adults with attention-deficit/hyperactivity disorder (ADHD). Here we investigated the relationship between ... -
Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders
Fanelli, Giuseppe; Franke, Barbara; De Witte, Ward; Ruisch, I. Hyun; Haavik, Jan; van Gils, Veerle; Jansen, Willemijn J.; Vos, Stephanie J. B.; Lind, Lars; Buitelaar, Jan K.; Banaschewski, Tobias; Dalsgaard, Søren; Serretti, Alessandro; Mota, Nina Roth; Poelmans, Geert; Bralten, Janita (Journal article; Peer reviewed, 2022)The prevalence of somatic insulinopathies, like metabolic syndrome (MetS), obesity, and type 2 diabetes mellitus (T2DM), is higher in Alzheimer’s disease (AD), autism spectrum disorder (ASD), and obsessive-compulsive ... -
Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum
Yang, Zhiyu; Wu, Hanrui; Lee, Phil H.; Tsetsos, Fotis; Davis, Lea K.; Yu, Dongmei; Lee, Sang Hong; Dalsgaard, Søren; Haavik, Jan; Barta, Csaba; Zayats, Tetyana; Eapen, Valsamma; Wray, Naomi R.; Devlin, Bernie; Daly, Mark; Neale, Benjamin; Børglum, Anders D.; Crowley, James J.; Scharf, Jeremiah; Mathews, Carol A.; Faraone, Stephen V.; Franke, Barbara; Mattheisen, Manuel; Smoller, Jordan W.; Paschou, Peristera (Journal article; Peer reviewed, 2021)Background Tourette syndrome (TS) is often found comorbid with other neurodevelopmental disorders across the impulsivity-compulsivity spectrum, with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder ... -
Involvement of the 14-3-3 Gene Family in Autism Spectrum Disorder and Schizophrenia: Genetics, Transcriptomics and Functional Analyses
Torrico, Bàrbara; Antón-Galindo, Ester; Fernàndez-Castillo, Noèlia; Rojo-Francàs, Eva; Ghorbani, Sadaf; Pineda-Cirera, Laura; Hervas, Amaia; Rueda, Isabel; Moreno, Estefanía; Fullerton, Janice M.; Casadó, Vicent; Buitelaar, Jan K; Rommelse, Nanda; Franke, Barbara; Reif, Andreas; Chiocchetti, Andreas G; Freitag, Christine; Kleppe, Rune; Haavik, Jan; Toma, Claudio; Cormand, Bru (Journal article; Peer reviewed, 2020)The 14-3-3 protein family are molecular chaperones involved in several biological functions and neurological diseases. We previously pinpointed YWHAZ (encoding 14-3-3ζ) as a candidate gene for autism spectrum disorder (ASD) ... -
Labor epidural analgesia and subsequent risk of offspring autism spectrum disorder and attention-deficit/hyperactivity disorder: A cross-national cohort study of over 4.5 million individuals and their siblings in Finland, Norway, and Sweden
Hegvik, Tor-Arne; Klungsøyr, Kari; Kuja-Halkola, Ralf; Remes, Hanna; Haavik, Jan; D*Onofrio, Brian M.; Metsä-Simola, Niina; Engeland, Anders; Fazel, Seena; Lichtenstein, Paul; Martikainen, Pekka; Larsson, Henrik; Sariaslan, Amir (Journal article; Peer reviewed, 2023)Background A recent study has suggested that labor epidural analgesia may be associated with increased rates of offspring autism spectrum disorder. Subsequent replication attempts have lacked sufficient power to confidently ... -
Male to female ratios in autism spectrum disorders by age, intellectual disability and attention-deficit/hyperactivity disorder
Posserud, Maj-Britt; Skretting Solberg, Berit; Engeland, Anders; Haavik, Jan; Klungsøyr, Kari (Journal article; Peer reviewed, 2021)Objective To examine the gender distribution in ASD in adults compared with children and the impact of comorbid intellectual disability (ID) and attention-deficit/hyperactivity disorder (ADHD) on the male to female ratio ... -
Personalized Medicine to Improve Treatment of Dopa-Responsive Dystonia—A Focus on Tyrosine Hydroxylase Deficiency
Nygaard, Gyrid; Szigetvari, Peter D.; Grindheim, Ann Kari; Ruoff, Peter; Martinez, Aurora; Haavik, Jan; Kleppe, Rune; Flydal, Marte I. (Journal article; Peer reviewed, 2021)Dopa-responsive dystonia (DRD) is a rare movement disorder associated with defective dopamine synthesis. This impairment may be due to the fact of a deficiency in GTP cyclohydrolase I (GTPCHI, GCH1 gene), sepiapterin ... -
Population prevalence and inheritance pattern of recurrent CNVs associated with neurodevelopmental disorders in 12,252 newborns and their parents
Smajlagic, Dinka; Lavrichenko, Ksenia; Berland, Siren; Helgeland, Øyvind; Knudsen, Gun Peggy Strømstad; Vaudel, Marc; Haavik, Jan; Knappskog, Per; Njølstad, Pål Rasmus; Houge, Gunnar; Johansson, Stefan (Journal article; Peer reviewed, 2020)Recurrent copy number variations (CNVs) are common causes of neurodevelopmental disorders (NDDs) and associated with a range of psychiatric traits. These CNVs occur at defined genomic regions that are particularly prone ... -
The quaternary structure of human tyrosine hydroxylase: effects of dystonia‐associated missense variants on oligomeric state and enzyme activity
Szigetvari, Peter Daniel; Muruganandam, Gopinath; Kallio, Juha; Hallin, Erik Ingmar; Fossbakk, Agnete; Loris, Remy; Kursula, Inari; Møller, Lisbeth Birk; Knappskog, Per; Kursula, Petri; Haavik, Jan (Journal article; Peer reviewed, 2019)Tyrosine hydroxylase (TH) is a multi-domain, homo-oligomeric enzyme that catalyses the rate-limiting step of catecholamine neurotransmitter biosynthesis. Missense variants of human TH are associated with a recessive ...