Now showing items 21-40 of 88

    • Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults 

      Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Journal article; Peer reviewed, 2021)
      Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ...
    • EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection 

      Lee, Yunsung; Riskedal, Espen; Kalleberg, Karl Trygve; Istre, Mette Stausland; Lind, Andreas; Lund-Johansen, Fridtjof; Reiakvam, Olaug Marie; Søraas, Arne Vasli; Harris, Jennifer Ruth; Dahl, John Arne; Lund Hadley, Cathrine; Jugessur, Astanand (Journal article; Peer reviewed, 2022)
      Although substantial progress has been made in managing COVID-19, it is still difficult to predict a patient’s prognosis. We explored the epigenetic signatures of COVID-19 in peripheral blood using data from an ongoing ...
    • The expansion of Acheulean hominins into the Nefud Desert of Arabia 

      Scerri, Eleanor M. L.; Frouin, Marine; Breeze, Paul S.; Armitage, Simon James; Candy, Ian; Groucutt, Huw S.; Drake, Nick; Parton, Ash; White, Tom S.; Alsharekh, Abdullah; Petraglia, Michael D. (Journal article; Peer reviewed, 2021)
      The Arabian Peninsula is a critical geographic landmass situated between Africa and the rest of Eurasia. Climatic shifts across the Pleistocene periodically produced wetter conditions in Arabia, dramatically altering the ...
    • Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cell culture assays 

      Hellesvik, Monica; Øye, Hanne; Aksnes, Henriette (Journal article; Peer reviewed, 2020)
      3D cell culture assays are becoming increasingly popular due to their higher resemblance to tissue environment. These provide an increased complexity compared to the growth on 2D surface and therefore allow studies of ...
    • Expression and regulation of FRMD6 in mouse DRG neurons and spinal cord after nerve injury 

      Lyu, Chuang; Lyu, Gong-Wei; Mulder, Jan; Uhlén, Mathias; Cai, Xue-Hui; Hökfelt, Tomas; Shi, Tie-Jun (Journal article; Peer reviewed, 2020)
      FRMD6, a member of the group of FERM-domain proteins, is involved both in communication between cells, interactions with extracellular matrix, cellular apoptotic and regenerative mechanisms. FRMD6 was first discovered in ...
    • Fatigue: a frequent and biologically based phenomenon in newly diagnosed celiac disease 

      Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Journal article; Peer reviewed, 2022)
      Fatigue is increasingly recognized as a major complaint in patients with chronic inflammatory and autoimmune diseases. Although fatigue is assumed to represent a significant problem in celiac disease, existing knowledge ...
    • Forest fragmentation modifes the composition of bumblebee communities and modulates their trophic and competitive interactions for pollination 

      Gómez-Martínez, Carmelo; Aase, Anne Lene Thorsdatter Orvedal; Totland, Ørjan; Rodríguez-Pérez, Javier; Birkemoe, Tone; Sverdrup-Thygeson, Anne; Lázaro, Amparo (Journal article; Peer reviewed, 2020)
      Understanding the effects of landscape fragmentation on global bumblebee declines requires going beyond estimates of abundance and richness and evaluating changes in community composition and trophic and competitive ...
    • Functional connectome differences in individuals with hallucinations across the psychosis continuum 

      Schutte, Maya J. L.; Bohlken, Marc M.; Collin, Guusje; Abramovic, Lucija; Boks, Marco P. M.; Cahn, Wiepke; Dauwan, Meenakshi; van Dellen, Edwin; van Haren, Neeltje E. M.; Hugdahl, Kenneth; Koops, Sanne; Mandl, René C. W.; Sommer, Iris E. C. (Journal article; Peer reviewed, 2021)
      Hallucinations may arise from an imbalance between sensory and higher cognitive brain regions, reflected by alterations in functional connectivity. It is unknown whether hallucinations across the psychosis continuum exhibit ...
    • Gene expression alterations in salivary gland epithelia of Sjögren’s syndrome patients are associated with clinical and histopathological manifestations 

      Dela Cruz, Ariana; Kartha, Vinay; Tilston-Lunel, Andrew; Mi, Rongjuan; Reynolds, Taylor L.; Mingueneau, Michael; Monti, Stefano; Jensen, Janicke Liaaen; Skarstein, Kathrine; Varelas, Xaralabos; Kukuruzinska, Maria A. (Journal article; Peer reviewed, 2021)
      Sjögren’s syndrome (SS) is a complex autoimmune disease associated with lymphocytic infiltration and secretory dysfunction of salivary and lacrimal glands. Although the etiology of SS remains unclear, evidence suggests ...
    • Genome- and transcriptomederived microsatellite loci in lumpfsh Cyclopterus lumpus: molecular tools for aquaculture, conservation and fsheries management 

      Maduna, Simo; Vivian-Smith, Adam; Jónsdóttir, Ólöf Dóra Bartels; Imsland, Albert; Klutsch, Cornelya; Nyman, Tommi; Eiken, Hans Geir; Hagen, Snorre (Journal article; Peer reviewed, 2020)
      The lumpfish Cyclopterus lumpus is commercially exploited in numerous areas of its range in the North Atlantic Ocean, and is important in salmonid aquaculture as a biological agent for controlling sea lice. Despite the ...
    • Global phylogeography suggests extensive eucosmopolitanism in Mesopelagic Fishes (Maurolicus: Sternoptychidae) 

      Rees, David John; Poulsen, Jan Yde; Sutton, Tracey T.; Costa, Paulo A C; Landaeta, Mauricio F (Journal article; Peer reviewed, 2020)
      Fishes in the mesopelagic zone (200–1000 m) have recently been highlighted for potential exploitation. Here we assess global phylogeography in Maurolicus, the Pearlsides, an ecologically important group. We obtained new ...
    • Glutamatergic modulation of auditory cortex connectivity with attentional brain networks in unpredictable perceptual environment 

      Kompus, Kristiina; Volehaugen, Vegard; Craven, Alexander R.; Specht, Karsten (Journal article; Peer reviewed, 2020)
      In a stable environment the brain can minimize processing required for sensory input by forming a predictive model of the surrounding world and suppressing neural response to predicted stimuli. Unpredicted stimuli lead to ...
    • Growth, clinical and neurodevelopmental outcomes at school age are similar for children who received 1‑year lamivudine or lopinavir/ritonavir HIV prophylaxis in early life 

      Nagot, Nicolas; Singata-Madliki, Mandisa; Cournil, Amandine; Nalugya, Joyce; Tassembedo, Soleymane; Quillet, Catherine; Tonga, Melany W.; Tumwine, James K; Meda, Nicolas; Kankasa, Chipepo; Mwiya, Mwiya; Bangirana, Paul; Peries, Marianne; Batting, Joanne; Engebretsen, Ingunn Marie Stadskleiv; Tylleskär, Thorkild; Van de Perre, Philippe; Ndeezi, Grace; Molès, Jean-Pierre (Journal article; Peer reviewed, 2021)
      In the ANRS 12174 trial, HIV-exposed uninfected African neonates who received lopinavir-ritonavir (LPV/r) prophylaxis for 1 year exhibited slower growth from birth to week 50 compared with those receiving lamivudine (3TC). ...
    • Helicobacter pylori was not detected in oral squamous cell carcinomas from cohorts of Norwegian and Nepalese patients 

      Pandey, Sushma; Follin-Arbelet, Benoit; Bahadur Pun, Chin; K. Gautam, Dej; Johannessen, Anne Christine; Petersen, Fernanda Cristina; Costea, Daniela Elena; Sapkota, Dipak (Journal article; Peer reviewed, 2020)
      Helicobacter pylori (HP) infection is an established causative agent for gastric cancer. Although the oral cavity is a part of the gastrointestinal system, the presence and possible causative role of HP in oral squamous ...
    • High expression of miR‑17‑5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients 

      Støen, Maria Jenvin; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona Irene; Ingebriktsen, Lise Martine; Bremnes, Roy M.; Dønnem, Tom; Lombardi, Ana Paola; Kilvær, Thomas Karsten; Rasmussen Busund, Lill-Tove; Richardsen, Elin (Journal article; Peer reviewed, 2021)
      MicroRNAs (miRs) are small non-coding RNA molecules, which are involved in the development of various malignancies, including prostate cancer (PCa). miR-17-5p is considered the most prominent member of the miR-17-92 cluster, ...
    • Human Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) 

      Lande, Asgeir; Fluge, Øystein; Strand, Elin Bolle; Flåm, Siri Tennebø; Sosa, Daisy Duarte; Mella, Olav; Egeland, Torstein; Saugstad, Ola Didrik; Lie, Benedicte Alexandra; Viken, Marte K (Journal article; Peer reviewed, 2020)
      The etiology and pathogenesis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) are unknown, and autoimmunity is one of many proposed underlying mechanisms. Human Leukocyte Antigen (HLA) associations are ...
    • Impact of the APOBEC3A/B deletion polymorphism on risk of ovarian cancer 

      Gansmo, Liv Beathe; Sofiyeva, Nigar; Bjørnslett, Merete Pauline; Romundstad, Pål Richard; Hveem, Kristian; Vatten, Lars Johan; Dørum, Anne; Lønning, Per Eystein; Knappskog, Stian (Journal article; Peer reviewed, 2021)
      A germline 29.5-kb deletion variant removes the 3’ end of the APOBEC3A gene and a large part of APOBEC3B, creating a hybrid gene that has been linked to increased APOBEC3 activity and DNA damage in human cancers. We genotyped ...
    • Incidence trends of airflow obstruction among European adults without asthma: a 20-year cohort study 

      Accordini, Simone; Calciano, Lucia; Marcon, Alessandro; Pesce, Giancarlo; Antó, Josep M.; Beckmeyer-Borowko, Anna B.; Carsin, Anne-Elie; Corsico, Angelo G.; Imboden, Medea; Janson, Christer; Keidel, Dirk; Locatelli, Francesca; Svanes, Cecilie; Burney, Peter G.J.; Jarvis, Deborah L.; Probst-Hensch, Nicole M.; Minelli, Cosetta (Journal article; Peer reviewed, 2020)
      Investigating COPD trends may help healthcare providers to forecast future disease burden. We estimated sex- and smoking-specific incidence trends of pre-bronchodilator airflow obstruction (AO) among adults without asthma ...
    • Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19 

      Jørgensen, Marthe Jøntvedt; Holter, Jan Cato; Christensen, Erik; Schjalm, Camilla; Tonby, Kristian; Pischke, Soeren; Jenum, Synne; Skeie, Linda Gail; Nur, Sarah; Lind, Andreas; Opsand, Hanne; Enersen, Tone Burvald; Grøndahl, Ragnhild; Hermann, Anne; Dudman, Susanne Gjeruldsen; Müller, Fredrik; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Heggelund, Lars; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma (Journal article; Peer reviewed, 2020-12)
      In SARS-CoV-2 infection there is an urgent need to identify patients that will progress to severe COVID-19 and may benefit from targeted treatment. In this study we analyzed plasma cytokines in COVID-19 patients and ...
    • An infant burial from Arma Veirana in northwestern Italy provides insights into funerary practices and female personhood in early Mesolithic Europe 

      Hodgkins, Jamie; Orr, Caley M.; Gravel-Miguel, Claudine; Riel-Salvatore, Julien; Miller, Christopher; Bondioli, Luca; Nava, Alessia; Lugli, Federico; Talamo, Sahra; Hajdinjak, Mateja; Cristiani, Emanuela; Romandini, Matteo; Meyer, Dominique; Drohobytsky, Danylo; Kuester, Falko; Pothier-Bouchard, Geneviève; Buckley, Mike; Mancini, Lucia; Baruffaldi, Fabio; Silvestrini, Sara; Arrighi, Simona; Keller, Hannah M.; Griggs, Rocío Belén; Peresani, Marco; Strait, David S.; Benazzi, Stefano; Negrino, Fabio (Journal article; Peer reviewed, 2021)
      The evolution and development of human mortuary behaviors is of enormous cultural significance. Here we report a richly-decorated young infant burial (AVH-1) from Arma Veirana (Liguria, northwestern Italy) that is directly ...