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    • MPCC: Strong stability of M-stationary points 

      Rückmann, Jan-Joachim; Hernández Escobar, Daniel; Günzel, Harald (Journal article; Peer reviewed, 2021)
      In this paper we study the class of mathematical programs with complementarity constraints MPCC. Under the Linear Independence constraint qualification MPCC-LICQ we state a topological as well as an equivalent algebraic ...

    • MPT64 antigen detection test improves diagnosis of pediatric extrapulmonary tuberculosis in Mbeya, Tanzania 

      Grønningen, Erlend; Nanyaro, Marywinnie; Sviland, Lisbet; Ngadaya, Esther; Muller, William; Torres, Lisete; Mfinanga, Sayoki; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)
      Pediatric extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. A new immunochemistry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests. The aim of this study ...

    • MRI adipose tissue segmentation and quantification in R (RAdipoSeg) 

      Haugen, Christine; Lysne, Vegard; Haldorsen, Ingfrid S.; Tjora, Erling; Gudbrandsen, Oddrun Anita; Sagen, Jørn Vegard; Dankel, Simon N; Mellgren, Gunnar (Journal article; Peer reviewed, 2022-10-08)
      Background: Excess adipose tissue is associated with increased cardiovascular and metabolic risk, but the volume of visceral and subcutaneous adipose tissue poses different metabolic risks. MRI with fat suppression can be ...

    • MRI-assessed tumor-free distance to serosa predicts deep myometrial invasion and poor outcome in endometrial cancer 

      Dybvik, Julie Andrea; Fasmer, Kristine Eldevik; Ytre-Hauge, Sigmund; Husby, Jenny Hild Aase; Salvesen, Øyvind; Stefansson, Ingunn Marie; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2022)
      Objectives To explore the diagnostic accuracy of preoperative magnetic resonance imaging (MRI)-derived tumor measurements for the prediction of histopathological deep (≥ 50%) myometrial invasion (pDMI) and prognostication ...

    • An mri-based radiomic prognostic index predicts poor outcome and specific genetic alterations in endometrial cancer 

      Jacob, Havjin; Dybvik, Julie Andrea; Ytre-Hauge, Sigmund; Fasmer, Kristine E.; Høivik, Erling Andre; Trovik, Jone; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2021)
      Integrative tumor characterization linking radiomic profiles to corresponding gene expression profiles has the potential to identify specific genetic alterations based on non-invasive radiomic profiling in cancer. The aim ...

    • MRI-based radiomic signatures for pretreatment prognostication in cervical cancer 

      Wagner-Larsen, Kari Strøno; Hodneland, Erlend; Fasmer, Kristine Eldevik; Lura, Njål; Woie, Kathrine; Bertelsen, Bjørn; Salvesen, Øyvind Olav; Halle, Mari Kyllesø; Smit, Noeska Natasja; Krakstad, Camilla; Haldorsen, Ingfrid S. (Journal article; Peer reviewed, 2023)
      Background Accurate pretherapeutic prognostication is important for tailoring treatment in cervical cancer (CC). Purpose To investigate whether pretreatment MRI-based radiomic signatures predict disease-specific ...

    • MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes 

      Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary; Valla, Marit (Journal article; Peer reviewed, 2020-01-16)
      Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy ...

    • MRTF specifies a muscle-like contractile module in Porifera 

      Colgren, Jeffrey John; Nichols, S.A. (Journal article; Peer reviewed, 2022)
      Muscle-based movement is a hallmark of animal biology, but the evolutionary origins of myocytes are unknown. Although believed to lack muscles, sponges (Porifera) are capable of coordinated whole-body contractions that ...

    • MtDNA sequence features associated with 'selfish genomes' predict tissue-specific segregation and reversion 

      Røyrvik, Ellen Christine; Johnston, Iain (Journal article; Peer reviewed, 2020)
      Mitochondrial DNA (mtDNA) encodes cellular machinery vital for cell and organism survival. Mutations, genetic manipulation, and gene therapies may produce cells where different types of mtDNA coexist in admixed populations. ...

    • Mucosal immune and stress responses of Neoparamoeba perurans-infected Atlantic salmon (Salmo salar) treated with peracetic acid shed light on the host-parasite-oxidant interactions 

      Lazado, Carlo C.; Strand, David; Breiland, Mette Serine Wesmajervi; Furtado, Francisco; Timmerhaus, Gerrit; Gjessing, Mona Cecilie; Hytterød, Sigurd; Merkin, Grigory; Pedersen, Lars Flemming; Pittman, Karin Anna; Krasnov, Aleksei (Journal article; Peer reviewed, 2022)
      Treatment development for parasitic infestation is often limited to disease resolution as an endpoint response, and physiological and immunological consequences are not thoroughly considered. Here, we report the impact of ...

    • Muddying the waters: reconsidering migration in the Neolithic of Britain, Ireland and Denmark 

      Cummings, Victoria; Hofmann, Daniela; Bjørnevad-Ahlkvist, Mathias; Iversen, Rune (Journal article; Peer reviewed, 2022)
      This paper explores the current narratives of migration for the start and spread of the Neolithic with a particular focus on the role that the new ancient DNA data have provided. While the genetic data are important and ...

    • Multi-, Cross-, Inter-, Transdisciplinarity – Fact or Fiction? Does Archaeology Need a Hand Blender? 

      Lindstrøm, Torill Christine (Journal article; Peer reviewed, 2022)
      The concepts multidisciplinarity, interdisciplinarity (crossdisciplinarity), and transdisciplinarity are defined, and examples are given. Whether interdisciplinarity is a novel development, a “new buzzword”, or a “new ...

    • Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk 

      Shrine, Nick; Izquierdo, Abril G.; Chen, Jing; Packer, Richard; Hall, Robert J.; Guyatt, Anna L.; Batini, Chiara; Thompson, Rebecca J.; Pavuluri, Chandan; Malik, Vidhi; Hobbs, Brian D.; Moll, Matthew; Kim, Wonji; Tal-Singer, Ruth; Bakke, Per S.; Fawcett, Katherine A.; John, Catherine; Coley, Kayesha; Piga, Noemi Nicole; Pozarickij, Alfred; Lin, Kuang; Millwood, Iona Y.; Chen, Zhengming; Li, Liming; Wijnant, Sara R A; Lahousse, Lies; Brusselle, Guy; Uitterlinden, Andre G.; Manichaikul, Ani; Oelsner, Elizabeth C.; Rich, Stephen S.; Barr, R Graham; Kerr, Shona M.; Vitart, Veronique; Brown, Michael R.; Wielscher, Matthias; Imboden, Medea; Jeong, Ayoung; Bartz, Traci M.; Gharib, Sina A.; Flexeder, Claudia; Karrasch, Stefan; Gieger, Christian; Peters, Annette; Stubbe, Beate; Hu, Xiaowei; Ortega, Victor E.; Meyers, Deborah A.; Bleecker, Eugene R.; Gabriel, Stacey B.; Gupta, Namrata; Smith, Albert Vernon; Luan, Jian'an; Zhao, Jing-Hua; Hansen, Ailin Falkmo; Langhammer, Arnulf; Willer, Cristen; Bhatta, Laxmi; Porteous, David; Smith, Blair H.; Campbell, Archie; Sofer, Tamar; Lee, Jiwon; Daviglus, Martha L.; Yu, Bing; Lim, Elise; Xu, Hanfei; O'Connor, George T.; Thareja, Gaurav; Albagha, Omar M E; Suhre, Karsten; Granell, Raquel; Faquih, Tariq O.; Hiemstra, Pieter S.; Slats, Annelies M.; Mullin, Benjamin H.; Hui, Jennie; James, Alan; Beilby, John; Patasova, Karina; Hysi, Pirro; Koskela, Jukka T.; Wyss, Annah B.; Jin, Jianping; Sikdar, Sinjini; Lee, Mikyeong; May-Wilson, Sebastian; Pirastu, Nicola; Kentistou, Katherine A.; Joshi, Peter K.; Timmers, Paul R H J; Williams, Alexander T.; Free, Robert C.; Wang, Xueyang; Morrison, John L.; Gilliland, Frank D.; Chen, Zhanghua; Wang, Carol A.; Foong, Rachel E.; Harris, Sarah E.; Taylor, Adele; Redmond, Paul; Cook, James P.; Mahajan, Anubha; Lind, Lars; Palviainen, Teemu; Lehtimäki, Terho; Raitakari, Olli T.; Kaprio, Jaakko; Rantanen, Taina; Pietiläinen, Kirsi H.; Cox, Simon R.; Pennell, Craig E.; Hall, Graham L.; Gauderman, W James; Brightling, Chris; Wilson, James F.; Vasankari, Tuula; Laitinen, Tarja; Salomaa, Veikko; Mook-Kanamori, Dennis O.; Timpson, Nicholas J.; Zeggini, Eleftheria; Dupuis, Josée; Hayward, Caroline; Brumpton, Ben Michael; Langenberg, Claudia; Weiss, Stefan; Homuth, Georg; Schmidt, Carsten Oliver; Probst-Hensch, Nicole; Jarvelin, Marjo-Riitta; Morrison, Alanna C.; Polasek, Ozren; Rudan, Igor; Lee, Joo-Hyeon; Sayers, Ian; Rawlins, Emma L.; Dudbridge, Frank; Silverman, Edwin K.; Strachan, David P.; Walters, Robin G.; Morris, Andrew P.; London, Stephanie J.; Cho, Michael H.; Wain, Louise V.; Hall, Ian P.; Tobin, Martin D. (Journal article; Peer reviewed, 2023)
      Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 ...

    • A multi-decadal record of oceanographic changes of the past ~165 years (1850-2015 AD) from Northwest of Iceland 

      Simon, Margit Hildegard; Muschitiello, Francesco; Tisserand, Amandine Aline; Olsen, Are; Moros, Matthias; Perner, Kerstin; Bårdsnes, Siv Tone; Dokken, Trond Martin; Jansen, Eystein (Journal article; Peer reviewed, 2020)
      Extending oceanographic data beyond the instrumental period is highly needed to better characterize and understand multi-decadal to centennial natural ocean variability. Here, a stable isotope record at unprecedented ...

    • Multi-Instrument Observations of the Evolution of Polar Cap Patches Associated With Flow Shears and Particle Precipitation 

      Zhang, Duan; Zhang, Qing-He; Oksavik, Kjellmar; Xing, Zan-Yang; Lyons, L.R.; Yang, Hui-Gen; Li, Guo-Jun; Hosokawa, Keisuke; Shinbori, Atsuki; Ma, Yu-Zhang; Wang, Yong; Wang, Xiang-Yu (Journal article; Peer reviewed, 2023)
      Simultaneous observations from Defense Meteorological Satellite Program, Swarm, Resolute Bay all-sky imagers, GPS Total Electron Content and Super Dual Auroral Radar Network, are used to investigate the evolution and key ...

    • A multi-layer perceptron network for perfusion parameter estimation in DCE-MRI studies of the healthy kidney 

      Klepaczko, Artur; Strzelecki, Michał; Kociołek, Marcin; Eikefjord, Eli Bjøvad; Lundervold, Arvid (Journal article; Peer reviewed, 2020)
      Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is an imaging technique which helps in visualizing and quantifying perfusion—one of the most important indicators of an organ’s state. This paper ...

    • Multi-level governance in a “Europe with the regions”. 

      Schakel, Arjan Hille (Journal article; Peer reviewed, 2020-08)
      The concept of multilevel governance was introduced to reveal the impact of regions on European Union (EU) policy making in Brussels. In this contribution, I show that multilevel governance also exposes regional involvement ...

    • A multi-model CMIP6-PMIP4 study of Arctic sea ice at 127 ka: sea ice data compilation and model differences 

      Kageyama, Masa; Sime, Louise C.; Sicard, Marie; Guarino, Maria-Vittoria; De Vernal, A; Stein, Ruediger; Schroeder, david; Malmierca-Vallet, Irene; Abe-Ouchi, Ayako; Bitz, Cecilia M.; Braconnot, Pascale; Brady, Esther C.; Cao, Jian; Chamberlain, Matthew; Feltham, Danny; Guo, Chuncheng; Legrande, Allegra N.; Lohmann, Gerrit; Meissner, Katrin; Menviel, Laurie; Nisancioglu, Kerim Hestnes; Otto-Bliesner, Bette L.; O'ishi, Ryouta; Ramos Buarque, Silvan; Salas y Mélia, David; Sherriff-Tadano, Sam; Stroeve, Julienne C.; Shi, Xiaoxu; Sun, Bo; Thomas, Robert; Volodin, Evgeny; Yeung, Nicholas K.H.; Zhang, Qiong; Zhang, Zhongshi; Zheng, Weipeng; Ziehn, Tilo (Journal article; Peer reviewed, 2021)
      The Last Interglacial period (LIG) is a period with increased summer insolation at high northern latitudes, which results in strong changes in the terrestrial and marine cryosphere. Understanding the mechanisms for this ...

    • Multi-omics and machine learning for the prevention and management of female reproductive health 

      Kharb, Simmi; Joshi, Anagha (Journal article; Peer reviewed, 2023)
      Females typically carry most of the burden of reproduction in mammals. In humans, this burden is exacerbated further, as the evolutionary advantage of a large and complex human brain came at a great cost of women’s ...

    • Multi-partonic medium induced cascades in expanding media 

      Adhya, Souvik Priyam; Salgado, Carlos A.; Spousta, Martin; Tywoniuk, Konrad (Journal article; Peer reviewed, 2022)
      Going beyond the simplified gluonic cascades, we introduce both gluon and quark degrees of freedom for partonic cascades inside the medium. We then solve the set of coupled evolution equations numerically with splitting ...