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Profiling of Small Ribosomal Subunits Reveals Modes and Regulation of Translation Initiation
(Journal article; Peer reviewed, 2020)Translation initiation is often attributed as the rate-determining step of eukaryotic protein synthesis and key to gene expression control. Despite this centrality, the series of steps involved in this process is poorly ... -
Prognosis in asymptomatic patients with discordantly graded aortic valve stenosis based on pressure recovery adjusted valve area
(Journal article; Peer reviewed, 2022)Objective: We hypothesised that patients with asymptomatic aortic stenosis (AS) who remain with discordantly graded aortic valve stenosis (DGAS) after adjustment for pressure recovery in the aortic root represents a subgroup ... -
Prognostic and predictive impact of stroma cells defned by PDGFRb expression in early breast cancer: results from the randomized SweBCG91RT trial
(Journal article; Peer reviewed, 2021)Purpose Predictive biomarkers are needed to aid the individualization of radiotherapy (RT) in breast cancer. Cancer-associated fibroblasts have been implicated in tumor radioresistance and can be identified by platelet-derived ... -
Prognostic value of baseline functional status measures and geriatric screening in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy – The randomized NORDIC9-study
(Journal article; Peer reviewed, 2023)Introduction Appropriate patient selection based on functional status is crucial when considering older adults for palliative chemotherapy. This pre-planned analysis of the randomized NORDIC9-study explored the prognostic ... -
The prognostic value of pre-treatment circulating biomarkers of systemic inflammation (CRP, dNLR, YKL-40, and IL-6) in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy—The Randomized NORDIC9-Study
(Journal article; Peer reviewed, 2022)Appropriate patient selection for palliative chemotherapy is crucial in patients with metastatic colorectal cancer (mCRC). We investigated the prognostic value of C-reactive protein (CRP), derived neutrophil-to-lymphocyte ... -
Prognostic value of the diversity of nuclear chromatin compartments in gynaecological carcinomas
(Journal article; Peer reviewed, 2020)Statistical texture analysis of cancer cell nuclei stained for DNA has recently been used to develop a pan-cancer prognostic marker of chromatin heterogeneity. In this study, we instead analysed chromatin organisation by ... -
Progress towards the 2020 fast track HIV/ AIDS reduction targets across ages in Ethiopia as compared to neighboring countries using global burden of diseases 2017 data
(Journal article; Peer reviewed, 2021)Background Sustainable Development Goal (SDG) 3.3, targets to eliminate HIV from being a public health threat by 2030. For better tracking of this target interim Fast Track milestones for 2020 and composite complementary ... -
The progression of acute myeloid leukemia from first diagnosis to chemoresistant relapse: A comparison of proteomic and phosphoproteomic profiles
(Journal article; Peer reviewed, 2020)Acute myeloid leukemia (AML) is an aggressive hematological malignancy. Nearly 50% of the patients who receive the most intensive treatment develop chemoresistant leukemia relapse. Although the leukemogenic events leading ... -
Progressive Changes in Magma Transport at the Active Serreta Ridge, Azores
(Journal article; Peer reviewed, 2019)Volcanism in the Eastern Azores Plateau occurs at large central volcanoes and along subaerial and submarine fissure zones, resulting from a mantle melting anomaly combined with transtensional stresses. Volcanic structures ... -
Progressive modulation of resting‑state brain activity during neurofeedback of positive‑social emotion regulation networks
(Journal article; Peer reviewed, 2021)Neurofeedback allows for the self-regulation of brain circuits implicated in specific maladaptive behaviors, leading to persistent changes in brain activity and connectivity. Positive-social emotion regulation neurofeedback ... -
Progressive Motor and Non-Motor Symptoms in Park7 Knockout Zebrafish
(Journal article; Peer reviewed, 2023)DJ-1 is a redox sensitive protein with a wide range of functions related to oxidative stress protection. Mutations in the park7 gene, which codes for DJ-1 are associated with early onset familial Parkinson’s disease and ... -
The proinflammatory cytokines TNF-α and IL-6 in lumpfish (Cyclopterus lumpus L.) -identification, molecular characterization, phylogeny and gene expression analyses
(Journal article; Peer reviewed, 2020)The proinflammatory cytokines TNF-α and IL-6 are important mediators of inflammatory reactions and orchestrators of the immune system in vertebrate. In this study, we have identified TNF-α and IL-6 in lumpfish, molecular ... -
Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa
(Journal article; Peer reviewed, 2023)Children recovering from severe malarial anaemia (SMA) remain at high risk of readmission and death after discharge from hospital. However, a recent trial found that post-discharge malaria chemoprevention (PDMC) with ... -
Prolonged grief, post-traumatic stress, and functional impairment in parents and siblings 8 years after the 2011 Utøya terror attack
(Journal article; Peer reviewed, 2022)Background: Research on bereavement after terrorism is limited and primarily aiming on short-term consequences. Objective: To better understand the long-term health consequences of terrorism, we studied bereaved parents ... -
Prolonging the delivery of influenza virus vaccine improves the quantity and quality of the induced immune responses in mice
(Journal article; Peer reviewed, 2023)Introduction: Influenza vaccines play a vital role in protecting individuals from influenza virus infection and severe illness. However, current influenza vaccines have suboptimal efficacy, which is further reduced in cases ... -
A Promise of Inclusion: On the Social Imaginary of Organised Encounters between Locals and Refugees
(Journal article; Peer reviewed, 2022)The present study contributes an empirical analysis that makes explicit a central social imaginary underpinning organised cultural encounters between ‘locals’ and immigrants: that contact between individuals who would not ... -
The promise of music therapy for Alzheimer's disease: A review
(Journal article; Peer reviewed, 2022)Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with cognitive decline. Memory problems are typically among the first signs of cognitive impairment in AD, and they worsen considerably as the ... -
Promoters and inhibitors for quality improvement work in general practice: a qualitative analysis of 2715 free-text replies
(Journal article; Peer reviewed, 2022)Background Continuous quality improvement (QI) is necessary to develop and maintain high quality general practice services. General Practitioners (GPs’) motivation is an important factor in the success of QI initiatives. ... -
Promoting 21st century skills through classroom encounters with English language literature in Norway: Theoretical and practical considerations
(Chapter, 2022)The present chapter explores the affordances of literature as an educational medium in the School of the Future, more specifically in relation to the teaching and learning of English as a Foreign Language (EFL) in Norway. ... -
Promoting aesthetical values to education
(Journal article; Peer reviewed, 2020)With a pressure on schools to meet the requirements of a knowledge-based global economy, human development, critical thinking and imagination seem to be given lower priority. This article argues for including the aesthetic ...