Blar i University of Bergen Library på forfatter "Nagot, Nicolas"
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Clinical and Biological Factors Associated with Early Epstein-Barr Virus Infection in Human Immunodeficiency Virus-Exposed Uninfected Infants in Eastern Uganda
Montoya-Ferrer, Ana; Sanosyan, Armen; Fayd'Herbe De Maudave, Alexis; Pisoni, Amandine; Bollore, Karine; Molès, Jean-Pierre; Peries, Marianne; Tylleskär, Thorkild; Tumwine, James K.; Ndeezi, Grace; Gorgolas, Miguel; Nagot, Nicolas; Van De Perre, Philippe; Tuaillon, Edouard (Journal article; Peer reviewed, 2021)Background Immune control of Epstein-Barr virus (EBV) infection is impaired in individuals with HIV. We explored maternal factors associated with EBV acquisition in HIV-exposed uninfected (HEU) infants and the relationship ... -
Design and challenges of a large HIV prevention clinical study on mother-to-child transmission: ANRS 12397 PROMISE-EPI study in Zambia and Burkina Faso
Mennecier, Anaïs; Kankasa, Chipepo; Fao, Paulin; Molès, Jean-Pierre; Eymard-Duvernay, Sabrina; Mwiya, Mwiya; Kania, Dramane; Chunda-Liyoka, Catherine; Sakana, Leticia; Rutagwera, David; Tassembedo, Souleymane; Wilfred-Tonga, Maria Melany; Mosqueira, Beatriz; Tylleskär, Thorkild; Nagot, Nicolas; Van De Perre, Philippe (Journal article; Peer reviewed, 2021)Post-natal HIV infection through breastfeeding remains a challenge in many low and middle-income countries, particularly due to non-availability of alternative infant feeding options and the suboptimal Prevention of Mother ... -
Eliminating HIV transmission through breast milk from women taking antiretroviral drugs
Goga, Ameena; Van de Perre, Philippe; Ngandu, Nobubelo; Nagot, Nicolas; Abrams, Elaine J; Moodley, Dhayendre; King, Rachel; Molès, Jean-Pierre; Chirinda, Witness; Scarlatti, Gabriella; Tylleskär, Thorkild; Sherman, Gayle G; Pillay, Yogan; Dabis, François; Gray, Glenda (Journal article; Peer reviewed, 2021) -
Eliminating postnatal HIV transmission in high incidence areas: need for complementary biomedical interventions
Van de Perre, Philippe; Goga, Ameena; Ngandu, Nobubelo; Nagot, Nicolas; Moodley, Dhayendre; King, Rachel; Molès, Jean-Pierre; Mosqueira, Beatriz; Chirinda, Witness; Scarlatti, Gabriella; Tylleskär, Thorkild; Dabis, François; Gray, Glenda (Journal article; Peer reviewed, 2021)The rate of mother-to-child transmission (MTCT) of HIV from breastfeeding is increasing relative to other causes of MTCT. Early effective preconception and antenatal antiretroviral therapy (ART) reduces intrauterine and ... -
Growth, clinical and neurodevelopmental outcomes at school age are similar for children who received 1‑year lamivudine or lopinavir/ritonavir HIV prophylaxis in early life
Nagot, Nicolas; Singata-Madliki, Mandisa; Cournil, Amandine; Nalugya, Joyce; Tassembedo, Soleymane; Quillet, Catherine; Tonga, Melany W.; Tumwine, James K; Meda, Nicolas; Kankasa, Chipepo; Mwiya, Mwiya; Bangirana, Paul; Peries, Marianne; Batting, Joanne; Engebretsen, Ingunn Marie Stadskleiv; Tylleskär, Thorkild; Van de Perre, Philippe; Ndeezi, Grace; Molès, Jean-Pierre (Journal article; Peer reviewed, 2021)In the ANRS 12174 trial, HIV-exposed uninfected African neonates who received lopinavir-ritonavir (LPV/r) prophylaxis for 1 year exhibited slower growth from birth to week 50 compared with those receiving lamivudine (3TC). ... -
Long-term persistence of mitochondrial DNA instability in HIV-exposed uninfected children during and after exposure to antiretroviral drugs and HIV
Desquiret-Dumas, Valérie; D’Ottavi, Morgana; Monnin, Audrey; Goudenège, David; Méda, Nicolas; Vizeneux, Amélie; Kankasa, Chipepo; Tylleskär, Thorkild; Bris, Céline; Procaccio, Vincent; Nagot, Nicolas; Van de Perre, Philippe; Reynier, Pascal; Molès, Jean-Pierre (Journal article; Peer reviewed, 2022)HIV-exposed uninfected (HEU) children show impaired health outcomes during childhood. A high rate of mitochondrial DNA (mtDNA) instability was reported in the blood of HEU at birth. We aimed to explore the relationship ... -
Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as Prophylaxis
Monnin, Audrey; Vizeneux, Amélie; Nagot, Nicolas; Eymard-Duvernay, Sabrina; Meda, Nicolas; Singata-Madliki, Mandisa; Ndeezi, Grace; Tumwine, James K; Kankasa, Chipepo; Goga, Ameena; Tylleskär, Thorkild; Van de Perre, Philippe; Molès, Jean-Pierre (Journal article; Peer reviewed, 2021)Telomere shortening can be enhanced upon human immunodeficiency virus (HIV) infection and by antiretroviral (ARV) exposures. The aim of this study was to evaluate the acute and long-term effect on telomere shortening of ... -
Mitochondrial DNA Instability Is Common in HIV-Exposed Uninfected Newborns
Monnin, Audrey; Desquiret-Dumas, Valérie; Meda, Nicolas; Goudenège, David; Bris, Céline; Kankasa, Chipepo; Singata-Madliki, Mandisa; Tylleskär, Thorkild; Procaccio, Vincent; Nagot, Nicolas; Van De Perre, Philippe; Reynier, Pascal; Molès, Jean-Pierre (Journal article; Peer reviewed, 2021)Worldwide, one million HIV-exposed uninfected (HEU) children are born yearly, and chronic health impairments have been reported in these children. Mitochondrial DNA (mtDNA) instability and altered mtDNA content have been ... -
Recurrent Severe Subclinical Mastitis and the Risk of HIV Transmission Through Breastfeeding
Rutagwera, David Gatsinzi; Molès, Jean-Pierre; Kankasa, Chipepo; Mwiya, Mwiya; Tuaillon, Edouard; Peries, Marianne; Nagot, Nicolas; Van de Perre, Philippe; Tylleskär, Thorkild (Journal article; Peer reviewed, 2022)Subclinical mastitis (SCM) is an important risk factor of postnatal HIV-1 transmission that is still poorly understood. A longitudinal sub-study of the ANRS12174 trial including 270 breastfeeding mothers in Lusaka, Zambia ...