Browsing University of Bergen Library by Journals "FEBS Open Bio"
Now showing items 1-4 of 4
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Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function
(Journal article; Peer reviewed, 2022)Hydroxymethylbilane synthase (HMBS) is the third enzyme involved in haem biosynthesis, in which it catalyses the formation of tetrapyrrole 1-hydroxymethylbilane (HMB). In this process, HMBS binds four consecutive substrate ... -
Functional characterization of all-trans retinoic acid-induced differentiation factor (ATRAID)
(Journal article; Peer reviewed, 2023)All-trans retinoic acid-induced differentiation (ATRAID) factor was first identified in HL60 cells. Several mRNA isoforms exist, but the respective proteins have not been fully characterized. In transfected cells expressing ... -
Structural insights into Charcot–Marie–Tooth disease-linked mutations in human GDAP1
(Journal article; Peer reviewed, 2022)Charcot–Marie–Tooth disease (CMT) is the most common inherited peripheral polyneuropathy in humans, and its different subtypes are linked to mutations in dozens of different genes. Mutations in ganglioside-induced ... -
Structure prediction of honey bee vitellogenin: a multi-domain protein important for insect immunity
(Journal article; Peer reviewed, 2022)Vitellogenin (Vg) has been implicated as a central protein in the immunity of egg-laying animals. Studies on a diverse set of species suggest that Vg supports health and longevity through binding to pathogens. Specific ...