Blar i University of Bergen Library på tidsskrift "Pharmaceutics"

Viser treff 1-9 av 9

    • Application of Antisolvent Precipitation Method for Formulating Excipient-Free Nanoparticles of Psychotropic Drugs 

      Wu, Carina; Wang, Wei (Journal article; Peer reviewed, 2022)
      The aim of the present study was to systematically examine the effects of variations in the process parameters of the antisolvent precipitation method employed in the preparation of excipient-free pure nanoparticles of ...

    • Low Molecular Weight Hydrogel for Wound Healing 

      Gu, Shangyan; Lu, Yu; Wang, Yuji; Lu, Wensheng; Wang, Wei (Journal article; Peer reviewed, 2023)
      Octadecylazanediyl dipropionic acid (C18ADPA) is a zwitterionic amphiphile with a dendritic headgroup. C18ADPA self-assembles to lamellar networks, which encompasses water and forms a low-molecular-weight hydrogel (LMWG). ...

    • Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells 

      Haugse, Ragnhild; Langer, Anika; Murvold, Elsa Thodesen; Costea, Daniela Elena; Gjertsen, Bjørn Tore; Gilja, Odd Helge; Kotopoulis, Spiros; Ruiz de Garibay, Gorka; McCormack, Emmet (Journal article; Peer reviewed, 2020)
      The use of ultrasound (US) and microbubbles (MB), usually referred to as sonoporation, has great potential to increase the efficacy of chemotherapy. However, the molecular mechanisms that mediate sonoporation response are ...

    • An NMR Study on Hydration and Molecular Interaction of Phytantriol‐Based Liquid Crystals 

      Lu, Yu; Zhu, Di; Le, Quynh Bao Truong; Wang, Yuji; Wang, Wei (Journal article; Peer reviewed, 2022-10-27)
      Phytantriol-based lyotropic liquid crystals (LLCs) have emerged as a new nanodrug delivery system. However, the understanding of phytantriol-based LLCs is lacking. In this study, we use NMR technology to characterize LLC ...

    • Pharmacokinetics and pharmacodynamics of t-cell bispecifics in the tumour interstitial fluid 

      Eigenmann, Miro Julian; Karlsen, Tine Veronica; Wagner, Marek; Tenstad, Olav; Weinzierl, Tina; Fauti, Tanja; Grimm, Hans Peter; Skogstrand, Trude; Klein, Christian; Sam, Johannes; Umana, Pablo; Bacac, Marina; Wiig, Helge; Walz, Antje-Christine (Journal article; Peer reviewed, 2021)
      The goal of this study is to investigate the pharmacokinetics in plasma and tumour interstitial fluid of two T-cell bispecifics (TCBs) with different binding affinities to the tumour target and to assess the subsequent ...

    • Review of Clinical Questions Submitted to Norwegian Drug Information Centres Concerning Administration and Dosage to Older Patients of Relevance to Patient-Centric Care 

      Schjøtt, Jan; Andreassen, Lillan Mo; Dale, Gro Helen; Stokes, Charlotte L. (Journal article; Peer reviewed, 2021)
      Patient-centric care entails optimising healthcare provision to patients based on their perspective and opinion. It involves appropriate treatment at a reasonable cost and a focus on patient characteristics in the ...

    • SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma? 

      Kotopoulis, Spiros; Popa, Mihaela-Lucia; Mayoral Safont, Mireia; Murvold, Elsa Thodesen; Haugse, Ragnhild; Langer, Anika; Dimcevski, Georg Gjorgji; Lam, Christina; Bjånes, Tormod Karlsen; Gilja, Odd Helge; Mccormack, Emmet Matin (Journal article; Peer reviewed, 2022)
      The use of ultrasound and microbubbles to enhance therapeutic efficacy (sonoporation) has shown great promise in cancer therapy from in vitro to ongoing clinical studies. The fastest bench-to-bedside translation involves ...

    • Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys 

      Eikrem, Øystein Solberg; Kotopoulis, Spiros; Popa, Mihaela-Lucia; Safont, Mireia Mayoral; Fossan, Kjell Ove; Leh, Sabine; Landolt, Lea; Babickova, Janka; Gudbrandsen, Oddrun Anita; Gilja, Odd Helge; Riedel, Bettina Maria Ingeborg; Schjøtt, Jan Didrik; McCormack, Emmet; Marti, Hans-Peter (Journal article; Peer reviewed, 2021-11-29)
      The use of ultrasound and microbubble-enhanced drug delivery, commonly referred to as sonoporation, has reached numerous clinical trials and has shown favourable results. Nevertheless, the microbubbles and acoustic path ...

    • Ultrasound- and Microbubble-Assisted Gemcitabine Delivery to Pancreatic Cancer Cells 

      Bjånes, Tormod Karlsen; Kotopoulis, Spiros; Murvold, Elsa Thodesen; Kamceva, Tina; Gjertsen, Bjørn Tore; Gilja, Odd Helge; Schjøtt, Jan; Riedel, Bettina; McCormack, Emmet (Journal article; Peer reviewed, 2020)
      Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death worldwide. Poor drug delivery to tumours is thought to limit chemotherapeutic treatment efficacy. Sonoporation combines ultrasound (US) and microbubbles ...