• Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response 

      Akkouh, Ibrahim; Hribkova, Hana; Grabiec, Marta; Budinska, Eva; Szabo, Attila; Kasparek, Tomas; Andreassen, Ole Andreas; Sun, Yuh-Man; Djurovic, Srdjan (Journal article; Peer reviewed, 2021)
      Astrocytes are the most abundant cell type in the human brain and are important regulators of several critical cellular functions, including synaptic transmission. Although astrocytes are known to play a central role in ...
    • Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder 

      Valstad, Mathias; Roelfs, Daniel; Slapø, Nora Berz; Timpe, Clara Marie Fides; Rai, Ahsan; Matziorinis, Anna Maria; Beck, Dani; Richard, Geneviève; Sæther, Linn Sofie; Haatveit, Beathe; Nordvik, Jan Egil; Hatlestad-Hall, Christoffer; Einevoll, Gaute T.; Mäki-Marttunen, Tuomo; Haram, Marit; Ueland, Torill; Lagerberg, Trine V.; Steen, Nils Eiel; Melle, Ingrid; Westlye, Lars T.; Jönsson, Erik Gunnar; Andreassen, Ole A.; Moberget, Torgeir; Elvsåshagen, Torbjørn (Journal article; Peer reviewed, 2021)
      Several lines of research suggest that impairments in long-term potentiation (LTP)-like synaptic plasticity might be a key pathophysiological mechanism in schizophrenia (SZ) and bipolar disorder type I (BDI) and II (BDII). ...
    • Hallucinations in older adults: A practical review 

      Badcock, Johanna C.; Larøi, Frank; Kamp, Karina; Kelsall-Foreman, India; Bucks, Romola S.; Weinborn, Michael; Begemann, Marieke; Taylor, John-Paul; Collerton, Daniel; O'Brien, John T.; El Haj, Mohamad; Ffytche, Dominic; Sommer, Iris Else Clara (Journal article; Peer reviewed, 2020)
      By 2050, it is estimated that 16% of people will be aged above 65 years, compared with 9% in 2019.1 Population aging is driving increased attention to the physical and mental health needs of older adults. Here, our focus ...
    • Hallucinations under psychedelics and in the schizophrenia spectrum: An interdisciplinary and multiscale comparison 

      Leptourgos, Pantelis; Fortier-Davy, Martin; Carhart-Harris, Robin; Corlett, Philip; Dupuis, David; Halberstadt, Adam L.; Kometer, Michael; Kozakova, Eva; Larøi, Frank; Noorani, Tehseen N.; Preller, Katrin H.; Waters, Flavie; Zaytseva, Yuliya; Jardri, Renaud (Journal article; Peer reviewed, 2020)
      The recent renaissance of psychedelic science has reignited interest in the similarity of drug-induced experiences to those more commonly observed in psychiatric contexts such as the schizophrenia-spectrum. This report ...
    • Modular-Level Functional Connectome Alterations in Individuals With Hallucinations Across the Psychosis Continuum 

      Schutte, Maya J. L.; Voppel, Alban; Collin, Guusje; Abramovic, Lucija; Boks, Marco P. M.; Cahn, Wiepke; van Haren, Neeltje E. M.; Hugdahl, Kenneth Jan; Koops, Sanne; Mandl, René C. W.; Sommer, Iris E. C. (Journal article; Peer reviewed, 2022)
      Functional connectome alterations, including modular network organization, have been related to the experience of hallucinations. It remains to be determined whether individuals with hallucinations across the psychosis ...
    • Neural activation in the ventromedial prefrontal cortex precedes conscious experience of being in or out of a transient hallucinatory state 

      Hugdahl, Kenneth; Craven, Alexander R.; Johnsen, Erik; Ersland, Lars; Stoyanov, Drozdstoy; Kandilarova, Sevdalina; Sandøy, Lydia Brunvoll; Kroken, Rune A.; Løberg, Else-Marie; Sommer, Iris E. (Journal article; Peer reviewed, 2022)
      Background and Hypotheses Auditory verbal hallucinations (AVHs) is not only a common symptom in schizophrenia but also observed in individuals in the general population. Despite extensive research, AVHs are poorly understood, ...
    • Neural Substrates of Psychotic Depression: Findings From the Global ECT-MRI Research Collaboration 

      Takamiya, Akihiro; Dols, Annemiek; Emsell, Louise; Abbott, Christopher; Yrondi, Antoine; Soriano-Mas, Carles; Jørgensen, Martin Balslev; Nordanskog, Pia; Rhebergen, Didi; van Exel, Eric; Oudega, Mardien L.; Bouckaert, Filip; Vandenbulcke, Mathieu; Sienaert, Pascal; Péran, Patrice; Cano, Marta; Cardoner, Narcis; Jørgensen, Anders; Paulson, Olaf B.; Hamilton, Paul; Kampe, Robin; Bruin, Willem; Bartsch, Hauke; Ousdal, Olga Therese; Kessler, Ute; van Wingen, Guido; Oltedal, Leif; Kishimoto, Taishiro (Journal article; Peer reviewed, 2021)
      Psychotic major depression (PMD) is hypothesized to be a distinct clinical entity from nonpsychotic major depression (NPMD). However, neurobiological evidence supporting this notion is scarce. The aim of this study is to ...
    • A review of multimodal hallucinations: categorization, assessment, theoretical perspectives, and clinical recommendations 

      Montagnese, Marcella; Leptourgos, Pantelis; Fernyhough, Charles; Waters, Flavie; Larøi, Frank; Jardri, Renaud; McCarthy-Jones, Simon; Thomas, Neil; Dudley, Rob; Taylor, John-Paul; Collerton, Daniel; Urwyler, Prabitha (Journal article; Peer reviewed, 2021)
      Hallucinations can occur in different sensory modalities, both simultaneously and serially in time. They have typically been studied in clinical populations as phenomena occurring in a single sensory modality. Hallucinatory ...
    • Sensory and Quasi-Sensory Experiences of the Deceased in Bereavement: An Interdisciplinary and Integrative Review 

      Kamp, Karina; Steffen, Edith Maria; Alderson-Day, Ben; Allen, Paul; Austad, Anne; Hayes, Jacqueline; Larøi, Frank; Ratcliffe, Matthew; Sabucedo, Pablo (Journal article; Peer reviewed, 2020)
      Bereaved people often report having sensory and quasi-sensory experiences of the deceased (SED), and there is an ongoing debate over whether SED are associated with pathology, such as grief complications. Research into ...