Browsing University of Bergen Library by Journals "Schizophrenia Bulletin"
Now showing items 1-12 of 12
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Clustering Schizophrenia Genes by Their Temporal Expression Patterns Aids Functional Interpretation
(Journal article; Peer reviewed, 2024)Background Schizophrenia is a highly heritable brain disorder with a typical symptom onset in early adulthood. The 2-hit hypothesis posits that schizophrenia results from differential early neurodevelopment, predisposing ... -
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response
(Journal article; Peer reviewed, 2021)Astrocytes are the most abundant cell type in the human brain and are important regulators of several critical cellular functions, including synaptic transmission. Although astrocytes are known to play a central role in ... -
Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder
(Journal article; Peer reviewed, 2021)Several lines of research suggest that impairments in long-term potentiation (LTP)-like synaptic plasticity might be a key pathophysiological mechanism in schizophrenia (SZ) and bipolar disorder type I (BDI) and II (BDII). ... -
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
(Journal article; Peer reviewed, 2023)Low vitamin D (vitD) levels have been consistently reported in schizophrenia (SCZ) suggesting a role in the etiopathology. However, little is known about the role of underlying shared genetic mechanisms. We applied a ... -
Hallucinations in older adults: A practical review
(Journal article; Peer reviewed, 2020)By 2050, it is estimated that 16% of people will be aged above 65 years, compared with 9% in 2019.1 Population aging is driving increased attention to the physical and mental health needs of older adults. Here, our focus ... -
Hallucinations under psychedelics and in the schizophrenia spectrum: An interdisciplinary and multiscale comparison
(Journal article; Peer reviewed, 2020)The recent renaissance of psychedelic science has reignited interest in the similarity of drug-induced experiences to those more commonly observed in psychiatric contexts such as the schizophrenia-spectrum. This report ... -
Modular-Level Functional Connectome Alterations in Individuals With Hallucinations Across the Psychosis Continuum
(Journal article; Peer reviewed, 2022)Functional connectome alterations, including modular network organization, have been related to the experience of hallucinations. It remains to be determined whether individuals with hallucinations across the psychosis ... -
Neural activation in the ventromedial prefrontal cortex precedes conscious experience of being in or out of a transient hallucinatory state
(Journal article; Peer reviewed, 2022)Background and Hypotheses Auditory verbal hallucinations (AVHs) is not only a common symptom in schizophrenia but also observed in individuals in the general population. Despite extensive research, AVHs are poorly understood, ... -
Neural Substrates of Psychotic Depression: Findings From the Global ECT-MRI Research Collaboration
(Journal article; Peer reviewed, 2021)Psychotic major depression (PMD) is hypothesized to be a distinct clinical entity from nonpsychotic major depression (NPMD). However, neurobiological evidence supporting this notion is scarce. The aim of this study is to ... -
A review of multimodal hallucinations: categorization, assessment, theoretical perspectives, and clinical recommendations
(Journal article; Peer reviewed, 2021)Hallucinations can occur in different sensory modalities, both simultaneously and serially in time. They have typically been studied in clinical populations as phenomena occurring in a single sensory modality. Hallucinatory ... -
Sensory and Quasi-Sensory Experiences of the Deceased in Bereavement: An Interdisciplinary and Integrative Review
(Journal article; Peer reviewed, 2020)Bereaved people often report having sensory and quasi-sensory experiences of the deceased (SED), and there is an ongoing debate over whether SED are associated with pathology, such as grief complications. Research into ... -
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
(Journal article; Peer reviewed, 2023)Background: Immune mechanisms are indicated in schizophrenia (SCZ). Recent genome-wide association studies (GWAS) have identified genetic variants associated with SCZ and immune-related phenotypes. Here, we use cutting ...