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The selenium content of SEPP1 versus selenium requirements in vertebrates

dc.contributor.authorPenglase, Samuel
dc.contributor.authorHamre, Kristin
dc.contributor.authorEllingsen, Ståle
dc.date.accessioned2016-07-05T11:41:18Z
dc.date.available2016-07-05T11:41:18Z
dc.date.issued2015-09-10
dc.PublishedPeerJ 2015, 3:e1244eng
dc.identifier.issn2167-8359en_US
dc.identifier.urihttp://hdl.handle.net/1956/12270
dc.description.abstractSelenoprotein P (SEPP1) distributes selenium (Se) throughout the body via the circulatory system. For vertebrates, the Se content of SEPP1 varies from 7 to 18 Se atoms depending on the species, but the reason for this variation remains unclear. Herein we provide evidence that vertebrate SEPP1 Sec content correlates positively with Se requirements. As the Se content of full length SEPP1 is genetically determined, this presents a unique case where a nutrient requirement can be predicted based on genomic sequence information.en_US
dc.language.isoengeng
dc.publisherPeerJen_US
dc.rightsAttribution CC BYeng
dc.rights.urihttp://creativecommons.org/licenses/by/4.0eng
dc.subjectSelenoprotein Peng
dc.subjectSelenium requirementseng
dc.subjectNutritioneng
dc.subjectSEPP1eng
dc.subjectSelenoproteineng
dc.titleThe selenium content of SEPP1 versus selenium requirements in vertebratesen_US
dc.typePeer reviewed
dc.typeJournal article
dc.date.updated2016-04-11T12:49:01Z
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2015 The Authorsen_US
dc.identifier.doihttps://doi.org/10.7717/peerj.1244
dc.identifier.cristin1303765


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